Category: esters-buliding-blocks

Effect of gamma-irradiation and extrusion on the physicochemical, thermal and aroma-active compounds of rice flour was written by Ayseli, Mehmet Turan;Coskun, Ismail. And the article was included in Radiation Physics and Chemistry in 2022.SDS of cas: 695-06-7 This article mentions the following:

Food irradiation seems to be an effective and safe method for preventing microbial and insect contamination in cereals. Interestingly, the determination of the aroma-active compounds in irradiated and extruded rice flour does not yet exist. This study aimed to investigate aroma and aroma-active compounds of non-irradiated rice flour (NIRF) and irradiated and processed rice flour (IPRF) by the SPME method combined with GC-MS-O. In the present study, twenty-three aroma-active compounds in the NIRF sample while fifteen in the IPRF sample were identified with 1.6-4.9 odor intensity scores. Hexanal [4.9], nonanal [4.4], heptanal [3.9], decanal [3.3], 3-Octen-2-one [3.1] and were detected as key odorants in all samples. Whereas, 2-penthylfuran [3.8], octanal [3.8], nonanal [4.5], and benzaldehyde [2.1] were clearly higher in the IPRF sample, considering NIRF. The amount of hexanal which can be considered as irradiation odor (IO), has been increased due to the food irradiation process. In the experiment, the researchers used many compounds, for example, 5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7SDS of cas: 695-06-7).

5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. SDS of cas: 695-06-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hydrophobically modified phosphogypsum and its application in polypropylene composites was written by Liu, Hao;Nie, Chenchen;Li, Hongping;Xie, Guiming;Cao, Jianxin. And the article was included in Construction and Building Materials in 2022.Recommanded Product: 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) This article mentions the following:

Phosphogypsum (PG) is a solid waste residue in the production of phosphoric acid by the wet process, and many deposits of this waste pollute the environment. Anhydrous Phosphogypsum (APG) was prepared by pretreatment of PG, after which its surface was hydroxylated by NaOH solution The surface hydrophobic modification of APG was achieved by grafting 3-(methacryloxy)propyltrimethoxysilane (KH570), alkoxytris(dioctyl pyrophosphate acyloxy) titanate (TCA-L38), and stearic acid (SA), resp., on hydroxylated APG surfaces. The chem. surface structure and properties of the APG materials were determined, and the mechanism of the hydrophobic surface modification was discussed. Finally, the modified APG was used as polypropylene (PP) filler to prepare PP composites by melt blending. The results showed that the hydroxyl content on the surface of APG was significantly increased after hydroxylation, which significantly increased the grafting rate of KH570, SA, and TCA-L38 on the surface of APG. KH570, SA, and TCA-L38 could react with the hydroxyl group of APG, which were closely adsorbed on the surface of APG by chem. adsorption. The water contact angles of APG-OH-KH570, APG-OH-SA, and APG-OH-TCA were 80.52鎺? 124.99鎺? and 123.77鎺? resp. The surface hydroxylation and hydrophobic modification of APG significantly improved the compatibility and interfacial interaction between APG and PP. The mech. properties APG-OH-KH570/PP, APG-OH-TCA/PP, and APG-OH-SA/PP composites were better than those of pure PP. In the experiment, the researchers used many compounds, for example, 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8Recommanded Product: 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate)).

2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Recommanded Product: 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor was written by Spencer, Emma S.;Dale, Edward J.;Gommans, Aimee L.;Rutledge, Malcolm T.;Vo, Christine T.;Nakatani, Yoshio;Gamble, Allan B.;Smith, Robin A. J.;Wilbanks, Sigurd M.;Hampton, Mark B.;Tyndall, Joel D. A.. And the article was included in European Journal of Medicinal Chemistry in 2015.Formula: C8H6FNS This article mentions the following:

Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that has roles in the innate immune response, and also contributes to inflammatory disease. While the biol. properties of MIF are closely linked to protein-protein interactions, MIF also has tautomerase activity. Inhibition of this activity interferes with the interaction of MIF with protein partners e.g. the CD74 receptor, and tautomerase inhibitors show promise in disease models including multiple sclerosis and colitis. Isothiocyanates inhibit MIF tautomerase activity via covalent modification of the N-terminal proline. We systematically explored variants of benzyl and phenethyl isothiocyanates, to define determinants of inhibition. In particular, substitution with hydroxyl, chloro, fluoro and trifluoro moieties at the para and meta positions were evaluated. In assays on treated cells and recombinant protein, the IC₅₀ varied from 250 nM to >100 娓璏. X-ray crystal structures of selected complexes revealed that two binding modes are accessed by some compounds, perhaps owing to strain in short linkers between the isothiocyanate and aromatic ring. The variety of binding modes confirms the existence of two subsites for inhibitors and establishes a platform for the development of potent inhibitors of MIF that only need to target one of these subsites. In the experiment, the researchers used many compounds, for example, 4-Fluorobenzylisothiocyanate (cas: 2740-88-7Formula: C8H6FNS).

4-Fluorobenzylisothiocyanate (cas: 2740-88-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Formula: C8H6FNS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Deuterated Clopidogrel Analogues as a New Generation of Antiplatelet Agents was written by Zhu, Yaoqiu;Zhou, Jiang;Jiao, Bo. And the article was included in ACS Medicinal Chemistry Letters in 2013.Electric Literature of C7H8O2S This article mentions the following:

Clopidogrel (CPG) is an antithrombotic prodrug that needs hepatic cytochrome P 450 (CYP) enzymes for its bioactivation. The clin. effects of CPG have been associated with high intersubject variability and a certain level of resistance. Recently, comprehensive biotransformation studies of CPG support that the observed clin. uncertainty stems from the low bioactivation efficiency, which is attributed to extensive attritional metabolism (e.g., hydrolysis of the Me ester functionality and oxidation of the piperidine moiety). With the goal of potentiating the desired thiophene 2-oxidation through minimal structural modification, we have adopted the strategy of targeted metabolism shift and have designed and synthesized deuterated piperidine analogs of CPG. In vitro studies showed that the prodrug activation percentages have been significantly increased for the deuterated analogs as a result of stability enhancement of the piperidine moiety. In a pharmacol. study with a rat model, oral administration of the deuterated analogs also demonstrated higher inhibitory activity than that of CPG against ADP (ADP) induced platelet aggregation. These deuterated analogs represent a new generation of antiplatelet agents with the potential to overcome the major clin. drawbacks of CPG. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Electric Literature of C7H8O2S).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 绾?valerolactone.Electric Literature of C7H8O2S

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Copper-Mediated Oxidative Transformation of N-Allyl Enamine Carboxylates toward Synthesis of Azaheterocycles was written by Toh, Kah Kah;Biswas, Anup;Wang, Yi-Feng;Tan, Yun Yun;Chiba, Shunsuke. And the article was included in Journal of the American Chemical Society in 2014.Formula: C9H10O3S This article mentions the following:

A method for synthesis of 3-azabicyclo[3.1.0]hex-2-enes has been developed by intramol. cyclopropanation of readily available N-allyl enamine carboxylates. Two complementary reaction conditions, CuBr-mediated aerobic and CuBr₂-catalyzed-PhIO₂-mediated systems effectively induced stepwise cyclopropanation via carbocupration of alkenes. Oxidative cyclopropane ring-opening of 5-substituted 3-azabicyclo[3.1.0]hex-2-enes was also developed for synthesis of highly substituted pyridines. In addition, diastereoselective reduction of 3-azabicyclo[3.1.0]hex-2-enes to 3-azabicyclo[3.1.0]hexanes was achieved using NaBH₃CN in the presence of acetic acid. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Formula: C9H10O3S).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Formula: C9H10O3S

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Conjugate addition of dialkylaluminum chlorides to alkylidenemalonic acid derivatives was written by Maas, Steffen;Stamm, Armin;Kunz, Horst. And the article was included in Synthesis in 1999.Related Products of 10203-58-4 This article mentions the following:

Complete regioselectivity is achieved in conjugate addition of dialkylaluminum chlorides with alkylidenemalonic esters, alkylidenecyanoacetates, and alkylidenemalononitrile to give 灏?branched carboxylate derivatives Sterically demanding products containing quaternary C atoms are obtained in good yields. In the case of Et₂AlCl, accompanying reduction of the substrates can be suppressed by application of BF₃ as an assisting Lewis acid. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Related Products of 10203-58-4).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 绾?valerolactone.Related Products of 10203-58-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Asymmetric cyclizations via a sequential Michael addition/Conia-ene reaction by combining multifunctional quaternary phosphonium salt and silver catalysis was written by Fang, Guosheng;Zheng, Changwu;Cao, Dongdong;Pan, Lu;Hong, Haoran;Wang, Hongyu;Zhao, Gang. And the article was included in Tetrahedron in 2019.HPLC of Formula: 1190-39-2 This article mentions the following:

A one-pot asym. Michael addition/Conia-ene reaction sequence, catalyzed by combination of a dipeptide-derived multifunctional quaternary phosphonium salt and Ag₂CO₃ was developed, which provided a series of synthetically important chiral methylenecyclopentane derivatives in moderate to excellent yields (up to 97%) and enantioselectivities (up to 93%). In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2HPLC of Formula: 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.HPLC of Formula: 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Thermoplastic polyurethane/butylene-styrene triblock copolymer blends: an alternative to tune wear behavior was written by Agnol, Lucas Dall;Toso, Giulio Tremea;Dias, Fernanda Trindade Gonzalez;Soares, Marcio Ronaldo Farias;Bianchi, Otavio. And the article was included in Polymer Bulletin (Heidelberg, Germany) in 2022.Application of 6683-19-8 This article mentions the following:

This work presents an interesting alternative for improving thermoplastic polyurethane’s (TPUs) tribol. properties by incorporating styrene-ethylene/butylene-styrene triblock copolymer (SEBS) via melt blending. Two TPUs with different molar masses, two compatibilizers SEBS-g-MA (C1) and SEBS-b-TPU (C2) and paraffinic oil were used in the formulated blends. The raw materials’ effect on the morphol., rheol., phys.-mech. and tribol. performance of TPU/SEBS blends was monitored. The phase morphol. achieved depended on the addition of mineral oil and compatibilizer agent type. The rheol. anal. showed a pseudo-liquid viscous behavior for all samples. However, this behavior was related to the compatibilizer type and molar mass of the TPU. No significant changes were observed between the compatibilizers C1 and C2 concerning the physicomech. properties. The fact that mineral oil is preferentially contained in the SEBS phase is the fundamental point to explain the blends phase morphol. and their rheol. and phys. behaviors. The swollen state SEBS modifies the TPU’s performance. It also allows tuning properties such as abrasion and increasing the friction coefficient, enabling promising applications for these thermoplastic elastomers blends. In the experiment, the researchers used many compounds, for example, 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8Application of 6683-19-8).

2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Application of 6683-19-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Syntheses of 5-fluorouracil-fat conjugates and evaluation of their in vitro cytotoxic activity was written by Lee, Heejoo;Chang, Pan Sup;Kim, Jae Wan;Jung, Ki Hwa;Shin, Soon Hee;Shin, Hae Soon;Jung, Soon Bog. And the article was included in Yakhak Hoechi in 1990.Category: esters-buliding-blocks This article mentions the following:

Fluorouracil amides I [R = (CH₂)₁₀Me, (CH₂)₁₆Me, (CH₂)₇(CH:CHCH₂)₂Bu, (CH₂)₇(CH:CHCH₂)₃Me, (CH₂)₁₀CO₂Me] were prepared as prodrugs by heating 5-fluorouracil in the RNCO. Preliminary testing for their antitumor effect was carried out on leukemia L1210 cells in culture. Most I, like fluorouracil, exhibited <50% inhibition growth at 1 鑴?10^-7M. Only I [R = (CH₂)₁₀CO₂Me] showed >50% inhibition at the same level. In the experiment, the researchers used many compounds, for example, 12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0Category: esters-buliding-blocks).

12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chemical composition, phenolic content and antioxidant capacity of Haloxylon scoparium extracts was written by Haida, S.;Kribii, A.. And the article was included in South African Journal of Botany in 2020.Recommanded Product: 4163-60-4 This article mentions the following:

This work is part of the valorization of the Haloxylon scoparium plant, belonging to the Chenopodiaceae family and native to southeastern of Morocco. The aim of the present work is to study the chem. composition of this plant, to estimate the phenolic compounds contents of its extracts and to evaluate their antioxidant powers. After extraction by maceration of the aerial and root part of Haloxylon scoparium, the extracts obtained are fractionated by liquid-liquid extraction using solvents of different polarities. The best extraction yield is obtained in the aerial part 23.54% against 10.99% for the root part. The anal. carried out by the coupling of gas chromatog. with mass spectrometry (GC-MS) shows that the root part contains mainly carbohydrates, however the aerial part consists mainly of alkaloids. The total polyphenol content obtained in the root part 69.86 mg/gEAG (mg/g of gallic acid) is significantly higher than that in the aerial part 56.79 mg/g EAG. The hydrolysable tannins are the predominant polyphenols of the root part of Haloxylon scoparium corresponding to 83.87 mg/g EAT (mg/g of tannic acid). The antioxidant activity of the various extracts obtained is evaluated by two methods: the DPPH (1,1-diphenyl-2-picryl hydrazyl) free radical scavenging test and the ferric reducing antioxidant power (FRAP). The examination of the inhibitory concentration values shows that the butanolic extract of the root part is the most active with values of IC₅₀ = 0.06 mg/mL and IC_0.5 = 0.19 mg/mL resp. for the DPPH and FRAP tests. The other extracts also showed a very interesting potential as antioxidants. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4Recommanded Product: 4163-60-4).

(2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: 4163-60-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics