Category: esters-buliding-blocks

Zhang, Huiyuan published the artcileA Sprayable and Visible Light Rapid-Cured Strippable Film for Surface Radioactive Decontamination, SDS of cas: 10287-53-3, the publication is Polymers (Basel, Switzerland) (2022), 14(5), 1008, database is CAplus and MEDLINE.

Strippable film is effective for removing radioactive contamination. However, it still has some limitations, such as the long curing time (about 30 min∼24 h) and the requirement of organic solvents. To address these issues, we report a simple protocol to prepare strippable decontamination films using liquid polybutadiene (LPB) and tert-Bu acrylate (TBA) as the raw materials without solvent and using camphorquinone/ethyl 4-dimethylaminobenzoate (CQ/EDB) as a photoinitiator, where the film was formed under household LED panel light or daylight irradiation for about 540 s. After a thorough study of viscosity, real-time Fourier transform IR (RT-FTIR spectra), gel and volatile organic compound (VOC) contents, mech. properties and decontamination efficiency, the optimum composition and curing conditions were determined for the decontamination strippable film. VOC content is as low as 12.7 ± 0.7and the resultant strippable film exhibits good mech. performances with a tensile strength of up to 5.4 ± 0.4 MPa and elongation of up to 66.6 ± 13. Most important, the decontamination efficiencies of this strippable film for 133CsCl on glass, ceramic and metal surfaces reach up to 98.1, 94.3and 97.6, resp.

Polymers (Basel, Switzerland) published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C18H28N2O7, SDS of cas: 10287-53-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wang, Xiao-tian published the artcileSynthesis of p-guanidinobenzoic acid hydrochloride and its derivative camostat mesylate, COA of Formula: C12H15NO4, the publication is Jingxi Huagong (2004), 21(8), 597-599, database is CAplus.

P-Aminobenzoic acid is stirred with cyanamide in water-bath at 50 °C, and then aqueous HCI [w(HCI) = 5%] is dropped to precipitate p-guanidinobenzoic acid hydrochloride (I) in 76.4% yield. In the presence of DCC (N,N’-dicyclohexylcarbodiimide), I reacts at first at room temperature (25°) with N,N-dimethylcarbamoylmethyl p-hydroxyphenylacetate, then the product is purified by changing it to carbonic salt, at last methanesulfonic acid is added to adjust pH to 3 to give camostat mesylate in 64.4% yield. This method is simple, and the materials are easy to get.

Jingxi Huagong published new progress about 59721-16-3. 59721-16-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Phenol,Ester,Amide, name is 2-(Dimethylamino)-2-oxoethyl 2-(4-hydroxyphenyl)acetate, and the molecular formula is C19H17N2NaO4S, COA of Formula: C12H15NO4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhang, Xiang-Jin published the artcileCascade Wolff Rearrangement/Acylation: A Metal-Free and Eco-Friendly Approach for 4-Hydroxy-pyrazolo[3,4-b]pyridin-6-ones and N-Pyrazole Amides Synthesis from 5-Aminopyrazoles and α-Diazoketones, HPLC of Formula: 30414-53-0, the publication is Journal of Organic Chemistry (2021), 86(23), 17471-17481, database is CAplus and MEDLINE.

A highly chemoselective cascade Wolff rearrangement/acylation reaction between 5-aminopyrazoles and diazo compounds has been developed. The protocol can facilitate the switchable synthesis of 4-hydroxy-pyrazolo[3,4-b]pyridin-6-ones I (R¹ = Me, Et, Ph, etc.; R² = Ph, t-Bu, 2-naphthyl, etc.; R³ = Ph, 4-MeOC₆H₄, 3-thienyl, etc.) and N-pyrazole amides II (R¹ = Me, t-Bu, Ph; R² = Ph, 4-FC₆H₄, 2-naphthyl, etc.; R³ = Me, c-hexyl, Ph, etc.; R⁴ = Me, Et) with the merits of a broad substrate scope, high functional group compatibility, and green and sustainable performance manner. All reactions proceeded efficiently without any catalyst and additives (acid and base) and resulted in the release of benign N₂, wherein di-Et carbonate served as a green benign solvent.

Journal of Organic Chemistry published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is C12H9N3O4, HPLC of Formula: 30414-53-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Qian, Xing-Kai published the artcileDiscovery of pyrazolones as novel carboxylesterase 2 inhibitors that potently inhibit the adipogenesis in cells, Synthetic Route of 30414-53-0, the publication is Bioorganic & Medicinal Chemistry (2021), 116187, database is CAplus and MEDLINE.

Carboxylesterase 2 (CES2) is one of the most important Phase I drug metabolizing enzymes in the carboxylesterase family. It plays crucial roles in the bioavailability of oral ester prodrugs and the therapeutic effect of some anticancer drugs such as irinotecan (CPT11) and capecitabine. In addition to the well-known roles of CES2 in xenobiotic metabolism, the enzyme also participates in endogenous metabolism and the production of lipids. In this study, we synthesized a series of pyrazolones and assayed their inhibitory effects against CES2 in vitro. Structure-activity relationship anal. of these pyrazolones (I) reveals that the introduction of 4-methylphenyl unit (R¹), 4-methylbenzyl (R²) and cyclohexyl (R³) moieties are beneficial for CES2 inhibition. Guided by these SARs results, 1-cyclohexyl-4-(4-methylbenzyl)-3-p-tolyl-1H-pyrazol-5(4H)-one (27, II) was designed and synthesized. Further investigations demonstrated that the compound 27 exhibited stronger CES2 inhibition activity with a lower IC₅₀ value (0.13μM). The inhibition kinetic study demonstrated that compound 27 inhibited the hydrolysis of CES2-fluorescein diacetate (FD) through non-competitive inhibition. In addition, the mol. docking showed that the core of pyrazolone, the cyclohexane moiety, 4-methylbenzyl and 4-methylphenyl groups in compound 27 all played important roles with the amino acid residues of CSE2. Also, compound 27 could inhibit adipocyte adipogenesis induced by mouse preadipocytes. In brief, we designed and synthesized a novel pyrazolone compound with a strong inhibitory ability on CES2 and could inhibit the adipogenesis induced by mouse preadipocytes, which can be served as a promising lead compound for the development of more potent pyrazolone-type CES2 inhibitors, and also used as a potential tool for exploring the biol. functions of CES2 in human being.

Bioorganic & Medicinal Chemistry published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is C6H10O3, Synthetic Route of 30414-53-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Jiang, Tiankai published the artcileComparison of UV resistance of HDPE added with hindered amine light stabilizers with different molecular structures, Recommanded Product: Tris(2,4-di-tert-butylphenyl) phosphite, the publication is Polymers for Advanced Technologies (2021), 32(3), 1288-1300, database is CAplus.

UV resistance of versatile plastics has been received attention for a long time, especially of high-d. polyethylene (HDPE). It was studied systematically that hindered amine light stabilizer (HALS) with different mol. structures had an effect on the UV resistance of HDPE. The mol. weights of the two HALS were 423.7 and 2100-3000 g/mol, resp. It was found that the low-mol.-weight HALS outperforms the polymeric one of HDPE matrix in UV resistances due to the different mol. structures. HDPE-containing HALS with different mol. structures followed different degradation mechanisms during artificial accelerated aging. In addition, HDPE matrix composites with low-mol.-weight HALS show better mech. properties than the polymeric one because of the decrease of delay of mol. chain fracture during irradiation Therefore, HDPE matrix composites with low-mol.-weight HALS have better UV degradation resistance. However, polymeric HALS has the advantage of hard to move out of the sample surface.

Polymers for Advanced Technologies published new progress about 31570-04-4. 31570-04-4 belongs to esters-buliding-blocks, auxiliary class Mono-phosphine Ligands, name is Tris(2,4-di-tert-butylphenyl) phosphite, and the molecular formula is C42H63O3P, Recommanded Product: Tris(2,4-di-tert-butylphenyl) phosphite.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Meng, Qiaoyu published the artcileThermal shock resistance study of stereolithographic additive-manufactured Al₂O₃ ceramics by in situ digital radiography, Name: Trimethylolpropane triacrylate, the publication is Ceramics International, database is CAplus.

Thermal shock resistance is critical to ensure the service safety of ceramic hot-end components. The thermal shock performance of stereolithog. additive-manufactured ceramics has not yet been studied. In this study, a series of thermal shock experiments with various temperature differences was conducted on stereolithog. additive-manufactured Al₂O₃ ceramics. The surface cracks were analyzed based on photographs captured before and after the thermal shock experiments Three-point bending tests with in situ X-ray digital radiog. were conducted to determine the thermal shock resistance. Crack initiation, propagation, and coalescence were observed under flexural loads. The critical temperature difference of the stereolithog. additive-manufactured Al₂O₃ ceramics was determined to be 267.22 °C. The crack length increased and residual strength decreased with increasing temperature differences. The layered structure of the stereolithog. additive-manufactured ceramics slowed crack propagation. We expect that this study will serve as a reference for the performance of stereolithog. additive-manufactured Al₂O₃ ceramics in extreme environments.

Ceramics International published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C15H20O6, Name: Trimethylolpropane triacrylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Liu, Rui-Zhe published the artcilePrecise Pentamers with Diverse Monomer Sequences and Their Thermal Properties, Application of Dimethyl fumarate, the publication is Chinese Journal of Polymer Science (2022), 40(5), 447-455, database is CAplus.

Sequenced-defined oligomer has been emerged as one of the hot topics in polymer chem. due to its capability of precisely controlling both chain length and monomer sequence. Recent efforts have focused on development of synthetic methodologies using state-of-the-art chem. tools. However, investigating the impact of minor changes in monomer sequence on phys. properties of these materials is still underdeveloped. Herein, four sequenced pentamers are synthesized by a reversible addition-fragmentation chain transfer (RAFT) single unit monomer insertion technique, in which a base pentamer possesses a relatively rigid backbone comprising of five cyclic monomer units. One of the cyclic units in this base pentamer is replaced by an acyclic monomer at different locations (the 1st, 3rd and 5th unit) to produce three modified pentamers, which leads to a significant decrease of glass transition temperature (Tg) compared to the base pentamer. Meanwhile, the modified pentamers with identical primary structures but distinct monomer sequences also present different T_g values depending on the position of the acyclic monomer unit. The middle (3rd) position of the acyclic unit causes profound decrease of T_g due to its increased mol. flexibility. These synthetic pentamers have been demonstrated to be excellent oligomeric plasticizers to modulate thermal transitions of bulk polymer materials.

Chinese Journal of Polymer Science published new progress about 624-49-7. 624-49-7 belongs to esters-buliding-blocks, auxiliary class Inhibitor,Natural product, name is Dimethyl fumarate, and the molecular formula is C6H8O4, Application of Dimethyl fumarate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhao, Qin published the artcileEffect of different boiling methods on flavor components of chicken skeleton soup, COA of Formula: C20H40O2, the publication is Shipin Gongye Keji (2015), 36(7), 314-319, database is CAplus.

The effect of atm. and high-pressure boiling method on amino acids of chicken skeleton soup was analyzed, and the volatile aromatic compounds were extracted by sold-phase micro-extraction (SPME) and analyzed by GC/MS. Results showed that high-pressure boiling had a significant effect on the content of amino acids and free amino acids (p < 0.05). Sixty-two and 54 kinds of volatile aromatic components were identified in high-pressure boiling and atm. boiling chicken skeleton soup resp. The varieties of volatile aromatic components in two kinds of chicken skeleton soups were similar. However, the contents of these various aromatic components were different. There was no significant difference on sensory evaluation of the two kinds of chicken skeleton soup. High-pressure boiling was a viable boiling process.

Shipin Gongye Keji published new progress about 110-34-9. 110-34-9 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester, name is Isobutyl palmitate, and the molecular formula is C18H34N4O5S, COA of Formula: C20H40O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Liu, Chang-ling published the artcileEffects of different reaction conditions on preparation of azobenzene polymer, Formula: C23H28N2O4, the publication is Jilin Huagong Xueyuan Xuebao (2015), 32(8), 72-74, database is CAplus.

Photoresponsive azobenzene polymer has very good applications in the fields of information storage, photonics, mol. switch, etc. This is the first achieved that the azobenzene polymer was prepared by atom transfer radical polymerization (ATRP), using the trimethylolpropane as the initiator of nuclear preparation and using azobenzene as the monomer. The structure of polymer was characterized by the IR spectroscopy (FTIR) and hydrogen NMR spectrometer (¹H-NMR), which showed that the desired product had been synthesized successfully. The influences of reaction time and concentration of monomer/initiator on the polymerization were investigated.

Jilin Huagong Xueyuan Xuebao published new progress about 135529-02-1. 135529-02-1 belongs to esters-buliding-blocks, auxiliary class azo,Alkenyl,Benzene,Ester,Ether, name is 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, and the molecular formula is C23H28N2O4, Formula: C23H28N2O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wang, Hong-Gang published the artcileItaconate aggravates experimental colitis, HPLC of Formula: 617-52-7, the publication is Clinics and Research in Hepatology and Gastroenterology (2021), 45(2), 101629, database is CAplus and MEDLINE.

Itaconate (ITA) is an immunometabolite derived by activated macrophages and exhibits potential anti-inflammatory activity. Previous studies have suggested that ITA derivatives such as di-Me ITA and 4-octyl ITA can significantly inhibit LPS induced macrophage activation and reduce the secretion of pro-inflammatory factors.

Clinics and Research in Hepatology and Gastroenterology published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C18H20N2O12, HPLC of Formula: 617-52-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics