Category: esters-buliding-blocks

Nickel-selective coated disk electrode based on carbon nanotube composite modified with a new Schiff base was written by Tashkhourian, J.;Ghaderizadeh, S. M.;Montazerozohori, M.. And the article was included in Russian Journal of Electrochemistry in 2015.Application of 106-79-6 This article mentions the following:

A coated disk polyvinyl chloride (PVC) matrix membrane ion-selective electrode for detection of nickel ion was fabricated based on multiwalled carbon nanotube composite modified with bis(2-hydroxyacetophenone)-1,2-propandiimine (BHAPN) as ionophore. The electrode showed a Nernstian slope of 29.7 ± 0.45 mV decade^-1 over a wide concentration range of 9.1 × 10^-7 to 2.0 x 10^-2 mol L^-1 of Ni(NO₃)₂ with detection limit of 3.2 x 10^-7 mol L^-1. This electrode was applicable in the pH range of 3.0-7.9 and had a short response time of approx. 6.0 s. The electrode exhibited good selectivity for Ni(II) relative to other metal ions. The use of multiwalled carbon nanotube (MWCNTs) in a polymer matrix improves the linear range and sensitivity of the electrode. The practical anal. utility of the electrode was demonstrated by the using it as an indicator electrode for potentiometric titration of Ni(II) ions with EDTA solution In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Application of 106-79-6).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 106-79-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Diastereomeric (η⁴-diene)Fe(CO)₃ complexes containing chiral amide groups: a convenient method for the resolution of amino acids was written by Schumacher, Marc;Coste, Gerald;Miesch, Laurence. And the article was included in Synthesis in 2009.Electric Literature of C12H23NO4 This article mentions the following:

Diastereomeric (η⁴-N-substituted-hexa-2,4-dienamide)Fe(CO)₃ complexes bearing chiral amide groups were used for the resolution of (η⁴-dienecarboxylic acid)Fe(CO)₃ complexes. Using the latter, enantiomerically pure proteinogenic or nonproteinogenic α-amino acids were prepared In the experiment, the researchers used many compounds, for example, Boc-D-Leu-OMe (cas: 133467-01-3Electric Literature of C12H23NO4).

Boc-D-Leu-OMe (cas: 133467-01-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Electric Literature of C12H23NO4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Straightforward Enantioselective Access to γ-Butyrolactones Bearing an All-Carbon β-Quaternary Stereocenter was written by Meninno, Sara;Fuoco, Tiziana;Tedesco, Consiglia;Lattanzi, Alessandra. And the article was included in Organic Letters in 2014.Application of 33166-79-9 This article mentions the following:

An enantioselective one-pot aldol/lactonization sequence has been developed to access highly challenging γ-butyrolactones bearing an all-carbon quaternary stereocenter at the β-position by reacting acylated succinic esters with aqueous formaldehyde in the presence of 3 mol % loading of a cinchona alkaloid-derived squaramide providing direct access to paraconic acid derivatives in high yield and fairly good level of enantioselectivity (up to 88% ee). Thus, e.g., keto diester I (R¹ = 2-phenyl-2-Pr, R³ = Me) + paraformaldehyde in presence of epi-hydroquinine-derived squaramide afforded lactone II in 79% yield and 78% ee. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Application of 33166-79-9).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 33166-79-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Stereocontrolled Alkylative Construction of Quaternary Carbon Centers was written by Kummer, David A.;Chain, William J.;Morales, Marvin R.;Quiroga, Olga;Myers, Andrew G.. And the article was included in Journal of the American Chemical Society in 2008.Related Products of 10203-58-4 This article mentions the following:

Protocols for the stereodefined formation of α,α-disubstituted enolates of pseudoephedrine amides are presented followed by the implementation of these in diastereoselective alkylation reactions. Direct alkylation of α,α-disubstituted pseudoephedrine amide substrates is demonstrated to be both efficient and diastereoselective across a range of substrates, as exemplified by alkylation of the diastereomeric pseudoephedrine α-methylbutyramides, where both substrates are found to undergo stereospecific replacement of the α-C-H bond with α-C-alkyl, with retention of stereochem. This is shown to arise by sequential stereospecific enolization and alkylation reactions, with the alkyl halide attacking a common π-face of the E- and Z-enolates, proposed to be opposite the pseudoephedrine alkoxide side chain. Pseudoephedrine α-phenylbutyramides are found to undergo highly stereoselective but not stereospecific α-alkylation reactions, which evidence suggests is due to facile enolate isomerization. Also α,α-disubstituted pseudoephedrine amide enolates can be generated in a highly stereocontrolled fashion by conjugate addition of an alkyllithium reagent to the s-cis-conformer of an α-alkyl-α,β-unsaturated pseudoephedrine amide, providing α,α-disubstituted enolate substrates that undergo alkylation in the same sense as those formed by direct deprotonation. Methods are presented to transform the α-quaternary pseudoephedrine amide products into optically active carboxylic acids, ketones, primary alcs., and aldehydes. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Related Products of 10203-58-4).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Related Products of 10203-58-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Minor groove DNA binders as antimicrobial agents. 1. Pyrrole tetraamides are potent antibacterials against vancomycin resistant enterococci and methicillin resistant Staphylococcus aureus was written by Dyatkina, Natalia B.;Roberts, Christopher D.;Keicher, Jesse D.;Dai, Yuqin;Nadherny, Joshua P.;Zhang, Wentao;Schmitz, Uli;Kongpachith, Ana;Fung, Kevin;Novikov, Alexander A.;Lou, Lillian;Velligan, Mark;Khorlin, Alexander A.;Chen, Ming S.. And the article was included in Journal of Medicinal Chemistry in 2002.COA of Formula: C7H8N2O4 This article mentions the following:

A new series of short pyrrole tetraamides are described whose submicromolar DNA binding affinity is an essential component for their strong antibacterial activity. This class of compounds is related to the linked bis-netropsins and bis-distamycins, but here, only one amino-pyrrole-carboxamide unit and an amidine tail is connected to either side of a central dicarboxylic acid linker. The highest degree of DNA binding, measured by compound-induced changes in UV melting temperatures of an AT-rich DNA oligomer, was observed for flat, aromatic linkers with no inherent bent, i.e., terephthalic acid or 1,4-pyridine-dicarboxylic acid. However, the antibacterial activity is critically linked to the size of the N-alkyl substituent of the pyrrole unit. None of the tetraamides with the commonly used methyl-pyrrole showed antibacterial activity. Isoamyl- or cyclopropylmethylene-substituted dipyrrole derivatives have the min. inhibitory concentrations in the submicromolar range. In vitro toxicity against human T-cells was studied for all compounds The degree to which compounds inhibited cell growth was neither directly correlated to DNA binding affinity nor directly correlated to antibacterial activity but seemed to depend strongly on the nature of the N-alkyl pyrrole substituents. In the experiment, the researchers used many compounds, for example, Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7COA of Formula: C7H8N2O4).

Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.COA of Formula: C7H8N2O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

I₂Cu-mediated self-sorting domino reaction of aryl β-ketoesters into symmetrical 2-carboalkoxy-1,4-enediones: application to synthesis of pyrazine, β-carboline and quinoxalines was written by Satish, Gandhesiri;Ilangovan, Andivelu. And the article was included in RSC Advances in 2015.Name: Ethyl 3-oxo-3-(thiophen-2-yl)propanoate This article mentions the following:

A self-sorting domino reaction of aryl β-ketoesters RC₆H₄C(O)CH₂C(O)OCH₂CH₃ into sym. E:Z mixture of 1,4-enediones RC(O)C(CO₂CH₂CH₃):CHC(O)R was reported by an I₂/Cu system. The reaction proceeds through tandem iodination, self-dimerization and Krapcho dealkoxycarbonylation in one pot under open air condition. Further, E:Z mixture of 1,4-enediones RC(O)C(CO₂CH₂CH₃):CHC(O)R were successfully employed for the synthesis of bioactive pyrazine, β-carboline and quinoxalines I via aza-Michael addition, intramol. cyclization and C-C bond cleavage of 1,3-dicarbonyl unit under mild reaction condition. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Name: Ethyl 3-oxo-3-(thiophen-2-yl)propanoate).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Name: Ethyl 3-oxo-3-(thiophen-2-yl)propanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Network Analysis of the Herb-Drug Interactions of Citrus Herbs Inspired by the “Grapefruit Juice Effect” was written by Lu, Jintao;Zhang, Dan;Zhang, Xiaomeng;Sa, Rina;Wang, Xiaofang;Wu, Huanzhang;Lin, Zhijian;Zhang, Bing. And the article was included in ACS Omega in 2022.Related Products of 105-87-3 This article mentions the following:

This study was performed to investigate the herb-drug interactions (HDIs) of citrus herbs (CHs), which was inspired by the “grapefruit (GF) juice effect”. Based on network anal., a total of 249 components in GF and 159 compounds in CHs exhibited great potential as active ingredients. Moreover, 360 GF-related genes, 422 CH-related genes, and 111 genes associated with drug transport and metabolism were collected, while 25 and 26 overlapping genes were identified. In compound-target networks, the degrees of naringenin, isopimpinellin, apigenin, sinensetin, and isoimperatorin were higher, and the results of protein-protein interaction indicated the hub role of UGT1A1 and CYP3A4. Conventional drugs such as erlotinib, nilotinib, tamoxifen, theophylline, venlafaxine, and verapamil were associated with GF and CHs via multiple drug transporters and drug-metabolizing enzymes. Remarkably, GF and CHs shared 48 potential active compounds, among which naringenin, tangeretin, nobiletin, and apigenin possessed more interactions with targets. Drug metabolism by cytochrome P 450 stood out in the mutual mechanism of GF and CHs. Mol. docking was utilized to elevate the protein-ligand binding potential of naringenin, tangeretin, nobiletin, and apigenin with UGT1A1 and CYP3A4. Furthermore, in vitro experiments demonstrated their regulating effect. Overall, this approach provided predictions on the HDIs of CHs, and they were tentatively verified through mol. docking and cell tests. Moreover, there is a demand for clin. and exptl. evidence to support the prediction. In the experiment, the researchers used many compounds, for example, (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3Related Products of 105-87-3).

(E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Related Products of 105-87-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Impact of Water on Odor-Active Compounds in Fermented and Dried Cocoa Beans and Chocolates Made thereof was written by Ullrich, Lisa;Neiens, Silva;Huhn, Tilo;Steinhaus, Martin;Chetschik, Irene. And the article was included in Journal of Agricultural and Food Chemistry in 2021.Related Products of 706-14-9 This article mentions the following:

The impact of water on odor-active compounds in fermented and dried cocoa beans as well as in chocolate either produced by a novel processing (NPC) or a traditional processing (TPC) technol. from the same batch of cocoa beans was investigated in this study. Quantitation of selected key odorants revealed significantly higher concentrations of Strecker aldehydes such as 3-(methylsulfanyl)propanal (66-fold) and phenylacetaldehyde (50-fold) after water treatment of the cocoa beans. The comparison of the two chocolates showed that higher amounts of the Strecker aldehydes 2-methylbutanal, 3-methylbutanal, and phenylacetaldehyde are released with water in the NPC (24-fold to 39-fold), compared to the TPC (7.3-fold-11-fold). In addition to Strecker aldehydes, the concentrations of many further characteristic key odorants of cocoa and chocolate increased after water treatment. Based on the results, a more intense retronasal odor perception of the analyzed compounds is expected due to their release during consumption in contact with saliva. In the experiment, the researchers used many compounds, for example, 5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9Related Products of 706-14-9).

5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Related Products of 706-14-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tuning Azoheteroarene Photoswitch Performance through Heteroaryl Design was written by Calbo, Joaquin;Weston, Claire E.;White, Andrew J. P.;Rzepa, Henry S.;Contreras-Garcia, Julia;Fuchter, Matthew J.. And the article was included in Journal of the American Chemical Society in 2017.Category: esters-buliding-blocks This article mentions the following:

A systematic computational and exptl. study to elucidate the origin of the long thermal half-lives and excellent addressability of the arylazopyrazoles is reported, and this understanding is used to determine important structure-property relationships for a wide array of comparable azoheteroaryl photoswitches. The authors identify compounds with Z isomer half-lives ranging from seconds to hours, to days and to years, and variable absorption characteristics, all through tuning of the heteroaromatic ring. Conformation perhaps plays the largest role in determining such properties: the compounds with the longest isomerization half-lives adopt a T-shaped ground state Z isomer conformation and proceed through a T-shaped isomerization pathway, whereas the most complete photoswitching is achieved for compounds that have a twisted (rather than T-shaped) Z isomer conformation. By balancing these factors, the authors report a new azopyrazole 3pzH, which can be quant. switched to its Z isomer ( > 98%) with 355 nm irradiation, near-quant. (97%) switched back to the E isomer with 532 nm irradiation, and has a very long half-life for thermal isomerization (t_1/2 = 74 d at 25 °C). In the experiment, the researchers used many compounds, for example, Ethyl 4-methyl-1H-pyrrole-3-carboxylate (cas: 2199-49-7Category: esters-buliding-blocks).

Ethyl 4-methyl-1H-pyrrole-3-carboxylate (cas: 2199-49-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of aromatic azomethines from 4′-aminopropiophenone, vanillin, vanillal, and their derivatives was written by Dikusar, E. A.;Potkin, V. I.;Kozlov, N. G.. And the article was included in Vestsi Natsyyanal’nai Akademii Navuk Belarusi, Seryya Khimichnykh Navuk in 2006.Reference of 20665-85-4 This article mentions the following:

New aromatic azomethines containing keto, ether and ester groups, e.g., (E)-I, were synthesized by reaction of vanillin, vanillal, and their esters with 4′-aminopropiophenone in anhydrous methanol. In the experiment, the researchers used many compounds, for example, 4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4Reference of 20665-85-4).

4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Reference of 20665-85-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics