Category: esters-buliding-blocks

Targeted and suspect screening of plasticizers in house dust to assess cumulative human exposure risk was written by Demirtepe, Hale;Melymuk, Lisa;Codling, Garry;Murinova, Lubica Palkovicova;Richterova, Denisa;Rasplova, Vladimira;Trnovec, Tomas;Klanova, Jana. And the article was included in Science of the Total Environment in 2021.Application In Synthesis of Dicyclohexyl phthalate This article mentions the following:

Indoor dust is an important exposure route to anthropogenic chems. used in consumer products. Plasticizers are common product additives and can easily leach out of the product and partition to dust. Investigations of plasticizers typically focus on a subset of phthalate esters (PEs), but there are many more PEs in use, and alternative plasticizers (APs) are seeing greater use after recognition of adverse health effects of PEs. In this study we use full scan high resolution mass spectrometry for targeted and suspect screening of PEs and APs in house dust and to assess the potential risk of human exposure. House dust samples from Eastern Slovakia were investigated and concentrations of âˆ?sub>12PEs and âˆ?sub>5APs ranged 12-2765μg/g and 45-13,260μg/g, resp. APs were at similar levels to PEs, indicating common usage of these compounds in products in homes. Evaluation of individual compound toxicity combined with human intake via dust ingestion suggested PEs are of lower priority compared to semivolatile organic compounds such as polychlorinated biphenyls due to their lower toxicity. However, cumulative risk assessment (CRA) is a more appropriate evaluation of risk, considering the presences of many PEs in dust and their similar toxic mode of action. CRA based on median toxicity reference values (TRVs) suggested acceptable risks for dust ingestion, however, the wide range of literature-derived TRVs is a large uncertainty, especially for the APs. Use of newer TRVs suggest risk from dust ingestion alone, i.e. not even considering diet, inhalation, and dermal contact. Addnl., screening of full-scan instrumental spectra identified a further 40 suspect PE compounds, suggesting the CRA based on the 12 target PEs underestimates the risk. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Application In Synthesis of Dicyclohexyl phthalate).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application In Synthesis of Dicyclohexyl phthalate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of (E)-azomethines from 4-aminobenzenesulfonamide (streptocide) derivatives was written by Dikusar, E. A.;Petkevich, S. K.;Potkin, V. I.;Stepin, S. G.. And the article was included in Vestsi Natsyyanal’nai Akademii Navuk Belarusi, Seryya Khimichnykh Navuk in 2015.Reference of 20665-85-4 This article mentions the following:

Synthesis of (E)-azomethines, derivatives of 4-aminobenzenesulfonamide (Streptocidum), by condensation of substituted vanillin-like benzaldehydes with streptocide in methanol, has been described. In the experiment, the researchers used many compounds, for example, 4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4Reference of 20665-85-4).

4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Reference of 20665-85-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effect of Monochamus galloprovincialis feeding on Pinus pinaster and Pinus pinea, oleoresin and insect volatiles was written by Goncalves, Elsa;Figueiredo, A. Cristina;Barroso, Jose G.;Henriques, Joana;Sousa, Edmundo;Bonifacio, Luis. And the article was included in Phytochemistry (Elsevier) in 2020.Product Details of 659-70-1 This article mentions the following:

In Portugal, the pine black sawyer Monochamus galloprovincialis is the principal vector of the pinewood nematode, Bursaphelenchus xylophilus, the causal agent of pine wilt disease (PWD), a lethal phyopathogen with major ecol. and economic consequences to European forestry. The aim of this study was to determine the influence of M. galloprovincialis feeding on the volatiles emitted by pine trees. This study focused on the pine species which are most relevant to Portugal, i.e., Pinus pinaster (maritime pine) and Pinus pinea (stone or umbrella pine), assessing to what extent pine chemotypes might influence feeding by the insect vector. Preliminary evaluation of each maritime pine essential oil allowed recognizing the existence of two main chemotypes (C1 and C2) and absence of chem. variability in P. pinea. Emission of volatiles from pine trees was evaluated before and during 24 h of feeding by a mixed-sex pair of newly emerged, unfed M. galloprovincialis. Volatiles were also collected from the oleoresin released from the feeding wounds as well as from the insects after feeding. Pine volatiles were collected by solid phase microextraction (SPME) and insect volatiles extracted with pentane, and all analyzed by gas chromatog.-mass spectrometry (GC-MS) and by GC for component identification and quantification, resp. Of the seventeen emitted volatiles detected in SPME analyses of P. pinaster, β-pinene, α-pinene, β-caryophyllene, and germacrene D showed the highest average fold increases as a result of M. galloprovincialis feeding. When grouped by P. pinaster chemotype, C1 and C2 groups of trees showed different patterns of responses. β-Caryophyllene and germacrene D showed the highest fold increase in C1 trees, whereas β-pinene and α-pinene clearly dominated in C2 trees. Likewise, the oleoresin volatiles from C1 trees were dominated by δ-3-carene and/or β-pinene, whereas α-pinene and β-pinene were the main volatile components from oleoresin of C2 trees. Nine components were detected in P. pinea volatiles, of which limonene showed the highest fold increase as a result of insect feeding. The volatiles collected from the insects after they had fed on P. pinaster included α-pinene, β-pinene, and abietic acid, and by the straight-chain n-alkanes n-C27, n-C29, and n-C25, together with the methyl-branched hydrocarbons 3-meC29, 2-meC28, and 3-meC27. A better understanding of the responses of different P. pinaster chemotypes to feeding by M. galloprovincialis may be helpful in the development of new lures to improve pine sawyer trapping in integrated pest management for control of PWD. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Product Details of 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Product Details of 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and in Vitro and in Vivo Evaluation of MMP-12 Selective Optical Probes was written by Bordenave, Thomas;Helle, Marion;Beau, Fabrice;Georgiadis, Dimitris;Tepshi, Livia;Bernes, Mylene;Ye, Yunpeng;Levenez, Laure;Poquet, Enora;Nozach, Herve;Razavian, Mahmoud;Toczek, Jakub;Stura, Enrico A.;Dive, Vincent;Sadeghi, Mehran M.;Devel, Laurent. And the article was included in Bioconjugate Chemistry in 2016.HPLC of Formula: 17920-23-9 This article mentions the following:

In designing new tracers consisting of a small peptide conjugated to a reporter of comparable size, particular attention needs to be paid to the selection of the reporter group, which can dictate both the in vitro and the in vivo performances of the whole conjugate. In the case of fluorescent tracers, this is particularly true given the large numbers of available dye moieties differing in their structures and properties. Here, the authors have studied the in vitro and in vivo properties of a novel series of MMP-12 selective probes composed of cyanine dyes varying in their structure, net charge, and hydrophilic character, tethered through a linker to a potent and specific MMP-12 phosphinic pseudopeptide inhibitor. The impact of linker length has been also explored. The crystallog. structure of one tracer in complex with MMP-12 has been obtained, providing the first crystal structure of a Cy5.5-derived probe and confirming that the binding of the targeting moiety is unaffected. MMP-12 remains the tracers’ privileged target, as attested by their affinity selectivity profile evaluated in solution toward a panel of 12 metalloproteases. In vivo assessment of four selected probes has highlighted not only the impact of the dye structure but also that of the linker length on the probes’ blood clearance rates and their biodistributions. These experiments also provided valuable data on the stability of the dye moieties in vivo. This has permitted the identification of one probe, which combines favorable binding to MMP-12 in solution and on cells with optimized in vivo performance including blood clearance rate suitable for short-time imaging. Through this series of tracers, the authors have identified various critical factors modulating the tracers’ in vivo behavior, which is both useful for the development and optimization of MMP-12 selective radiolabeled tracers and informative for the design of fluorescent probes in general. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9HPLC of Formula: 17920-23-9).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.HPLC of Formula: 17920-23-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Aromatic Profiles and Enantiomeric Distributions of Chiral Volatile Compounds in Pu-Erh Tea was written by Zhu, JianCai;Niu, YunWei;Xiao, ZuoBing. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Electric Literature of C9H10O3 This article mentions the following:

Pu-Erh tea, as a typical post-fermented tea, can be divided into raw Pu-Erh tea (RAPT) and ripened Pu-Erh tea (RIPT) according to the processing technol. It is famous for its unique aroma after aging. Although previous research on the aroma characteristics of Pu-Erh tea mostly focused on the aroma compounds, little research on chiral compounds in RAPT and RIPT has been performed. Therefore, the current work aims to explore the aroma characteristics of Pu-Erh tea from the perspective of enantiomers of chiral compounds A total of 15 enantiomers were determined in this study, among which (R)-(-)-2,2,6-trimethylcyclohexanone, (R)-(-)-linalool, (S)-(+)-linalool, (R)-(+)-δ-octanolactone, (R)-(+)-γ-nonanolactone, (2R,5R)-(+)-theaspirone A, and (R)-(-)-dihydroactinidiolide were identified as enantiomeric compounds that play an important role in the aroma of RAPT and RIPT. Furthermore, (2S,5R)-trans-linalool oxide and (R)-(+)-α-terpineol were important contributors to the aroma profile of RAPT, while (S)-(+)-2-methylbutanal, (S)-(-)-limonene, S-(-)-α-terpineol, and (1R,2R)-(-)-Me jasmonate contributed to the characteristic aroma of RIPT. The addition of these enantiomeric compounds brings the aroma closer to that of the original tea sample. In addition, the anal. of chiral enantiomers of linalool, limonene, theaspirone A, and γ-nonanolactone can provide guidance for the quality and flavor control of Pu-Erh tea aroma. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxybenzoate (cas: 118-61-6Electric Literature of C9H10O3).

Ethyl 2-hydroxybenzoate (cas: 118-61-6) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Electric Literature of C9H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Luminescence and Configurations of Perylene Dimers in a Langmuir-Blodgett Film was written by Mahrt, J.;Willig, F.;Storck, W.;Weiss, D.;Kietzmann, R.;Schwarzburg, K.;Tufts, B.;Troesken, B.. And the article was included in Journal of Physical Chemistry in 1994.Quality Control of 12-Methoxy-12-oxododecanoic acid This article mentions the following:

Luminescence and excitation spectra of a Langmuir-Blodgett multilayer with a high concentration of densely packed perylene chromophores are measured at 2 K. They are compared with corresponding spectra of the dimeric α-perylene crystal and of perylene dimers formed in a glass. The majority of the perylene chromophores are arrested in the Langmuir-Blodgett film in the form of open metastable dimer configurations with monomer-like spectra. They dominate the absorption spectrum and excitation spectrum of luminescence. From these open dimers the excitation energy is rapidly transferred to the lower excited state of a stable dimer species functioning as a trap. Luminescence from this excited g-state leads to the peak at 550 nm in the luminescence spectrum. A second peak at 630 nm and the red side of the luminescence spectrum are due to E-excimer luminescence. The wide spectral range of the luminescence, extending from below 500 nm up to 800 nm, reflects sub-angstrom differences in the configurations of the dimers. In the experiment, the researchers used many compounds, for example, 12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0Quality Control of 12-Methoxy-12-oxododecanoic acid).

12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Quality Control of 12-Methoxy-12-oxododecanoic acid

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Studies on Cyclic Ketones. I was written by Ruhemann, Siegfried. And the article was included in Journal of the Chemical Society, Transactions in 1912.Product Details of 39163-39-8 This article mentions the following:

(CO₂Et)₂, NaOEt, and cyclopentanone, in Et₂O, gave ethyl cyclopentanone-2,5-dioxalate (I), deep yellow plates, m. 114-5°, and ethyl cyclopentanone-2-oxalate, yellow, b₁₅ 152-3°; needles, m. 26-7°. Both esters give deep red colors with FeCl₃. (I) gives a salt containing 2 mols. PhNHNH₂; colorless crystals. Cyclopentanone 2,5-dioxalic acid, yellow needles, m. 210° (decompose). (CO₂Et)₂, NaOEt, and 1-methyl-cyclopentane-3-one form only ethyl 1-methylcyclopentane-3-one-4-oxalate, pale yellow oil, b₁₄ 150°. Ethyl 1,3-dimethyl-Δ³-cyclohexene-5-one-6-oxalate (II), yellow needles, m. 132-3°. Acid, yellow prisms, m. 178° (decompose). Ethyl 1-hydrindone-2-oxalate (III), colorless needles, m. 74-5°. Salt with 1 PhNHNH₂, colorless crystals; unstable. Acid, faintly yellow needles, m. 214° (decompose). 5,6-Methylenedioxy-1-hydrindone-β-oxalic acid, using C₆H₆ as solvent and hydrolyzing the ester, which could not be purified, yellow needles, m. 260° (decompose). (III), heated in EtOH with PhNHNH₂.HCl and a little HCl, gave ethyl 1-phenyl-4,5-indenopyrazole-3-carboxylate (IV), pale yellow needles, m. 117-8°. Acid, needles, m. 250-1° (decompose); also prepared direct from the acid of (III). Silver salt, curdy, not attacked by light. Ethyl 4,5-indenopyrazole-3-carboxylate, colorless prisms, m. 174°. Acid, very slightly soluble, m. 310° (decompose). α-Hydrindone, NaOEt, and PhC îŒ?CCO₂Et yielded 6-phenyl-2,3-indeno-4-pyrone (V), needles, with 1 H₂O, m. 169° (for this reaction cf. C. A., 2, 1830, 3062). Chloroplatinate, plates. p-ONC₆H₄NMe₂ acts on 1,3-dimethyl-Δ³-cyclohexene-5-one and succinylosuccinic ester as an oxidizing agent, instead of condensing with these. An additional double bond is introduced into the cyclic ketone and the base is reduced to Me₂NC₆H₄N₂OC₆H₄NMe₂. In the experiment, the researchers used many compounds, for example, Ethyl 2-oxo-2-(2-oxocyclopentyl)acetate (cas: 39163-39-8Product Details of 39163-39-8).

Ethyl 2-oxo-2-(2-oxocyclopentyl)acetate (cas: 39163-39-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Product Details of 39163-39-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Compound-Specific Radiocarbon Analysis of Low Molecular Weight Dicarboxylic Acids in Ambient Aerosols Using Preparative Gas Chromatography: Method Development was written by Xu, Buqing;Cheng, Zhineng;Gustafsson, Orjan;Kawamura, Kimitaka;Jin, Biao;Zhu, Sanyuan;Tang, Tiangang;Zhang, Bolong;Li, Jun;Zhang, Gan. And the article was included in Environmental Science & Technology Letters in 2021.Recommanded Product: 1190-39-2 This article mentions the following:

Low mol. weight dicarboxylic acids constitute a large fraction of atm. organic aerosols, which impact atm. radiative forcing and hence Earth’s climate. Radiocarbon (¹⁴C) is a unique approach to unambiguously distinguishing the relative contributions of biomass-derived and fossil sources. Here, we developed a compound-specific radiocarbon anal. (CSRA) method for individual dicarboxylic acids in atm. particulates. Specifically, the method starts with a di-Bu ester derivatization technique, followed by separation and harvesting of single compounds employing a preparative capillary gas chromatog. in sufficient amounts for offline ¹⁴C measurement with accelerator mass spectrometry. The optimized preparative steps yielded recoveries of >60% and purities of >99% for target mols. The radiocarbon isotope compositions determined for reference standards taken through the entire method agree well with the original composition of each standard (R² = 0.9998). The applicability of the approach was demonstrated with ambient aerosol samples representing contrasting air mass regimes. This yielded two radically different yet system-consistent precursor sources. A min. size of 50μg of C of ambient dicarboxylic acids is needed for credible ¹⁴C measurement. The established method for CSRA of dicarboxylic acids demonstrates a new anal. dimension for studies of the source and evolution of atm. secondary organic aerosols. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Recommanded Product: 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Metal-free Catalytic Esterification of Aryl Alkyl Ketones with Alcohols via Free-radical Mediated C(sp³)-H Bond Oxygenation was written by Rammurthy, Banothu;Peraka, Swamy;Vasu, Amrutham;Krishna Sai, Gajula;Divya Rohini, Yennamaneni;Narender, Nama. And the article was included in Asian Journal of Organic Chemistry in 2021.Safety of Methyl 4-(2-hydroxyphenyl)butanoate This article mentions the following:

A novel metal-free catalytic one-pot approach has been developed for the esterification of aralkyl ketones RC(O)R¹ (R = Ph, naphth-2-yl, 2-bromophenyl, etc.; R¹ = Me, Et, benzyl) with alcs. R²OH (R² = Me, Et, i-Pr, n-Bu) under open-air atm. conditions. The inexpensive iodide/oxone reagent system allowed the cascade C(sp₃)-H bond oxygenation, selective C-C bond cleavage and esterification through the both radical and ionic pathways in a stepwise manner in one-pot. This mild, convenient and economically viable catalytic method tolerates the various functional groups to provide the corresponding alkyl benzoates RC(O)OR² in up to 98% yields with up to 99% selectivity. The efficiency and feasibility of scale-up of the present catalytic system were demonstrated with gram scale experiments (up to 10 g scale). In the experiment, the researchers used many compounds, for example, Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7Safety of Methyl 4-(2-hydroxyphenyl)butanoate).

Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Safety of Methyl 4-(2-hydroxyphenyl)butanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Development of a multiclass method to quantify phthalates, pharmaceuticals, and personal care products in river water using ultra-high performance liquid chromatography coupled with quadrupole hybrid Orbitrap mass spectrometry was written by Rendedula, Deviprasad;Satyanarayana, Gubbala Naga Venkata;Asati, Ankita;Kaliyaperumal, Muralidharan;Mudiam, Mohana Krishna Reddy. And the article was included in Analytical Science Advances in 2021.Synthetic Route of C20H26O4 This article mentions the following:

Rationale : The organic micropollutants such as phthalates, pharmaceuticals, and personal care products (PPPCPs) enter the surface water through various routes. The aim of this study is to develop a sensitive and efficient method to identify and quantify 26 PPPCPs found in river water with acceptable accuracy and precision using a liquid chromatograph hyphenated with quadrupole hybrid Orbitrap mass spectrometry (Q-Orbitrap-MS) in a single chromatog. run. Method : The organic micropollutants were extracted from river water by solid-phase extraction (SPE) using hydrophilic-lipophilic balance sorbent and analyzed using an ultra-high performance liquid chromatograph (UHPLC) equipped with C18 stationary phase for chromatog. separation The targeted mass experiments were conducted in a Q-Orbitrap-MS system in pos. and neg. electrospray ionization mode. Results : The method was found to be linear in the concentration range of 1-125 ng/L with coefficient of determination lying in the range of 0.995-0.999. The method achieved limit of quantification in the range of 0.41-1.72 ng/L, and method recovery measured at three different concentrations was found to be in the range of 75-115%. Intra- and interday precision expressed as percent relative standard deviation was found to be <15%. Matrix effect was found to be in the range of 83.5-109.79%. The matrix match calibration was used for quantification of PPPCPs in river water sample. The method performance was evaluated by analyzing real samples collected from Ganga River, and the concentrations of 21 analytes were found to be in the range of 0.76-9.49 ng/L for pharmaceuticals, 1.49-8.67 ng/L for phthalates, and 0.9-7.58 ng/L for personal care products. Conclusions : The present method was found to be precise, sensitive, and rapid to determine 26 PPPCPs including phthalates in river water samples using SPE-UHPLC-Q-Orbitrap-MS. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Synthetic Route of C20H26O4).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Synthetic Route of C20H26O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics