Category: esters-buliding-blocks

Modified clerodanes from the essential oil of Dodonea viscosa leaves was written by Anonymous. And the article was included in Molecules in 2020.Recommanded Product: 659-70-1 This article mentions the following:

Dodonea viscosa (L.) Jacq from Reunion Island (Indian Ocean) was investigated for its leaf essential oil composition The plant was extracted by hydrodistillation and its essential oil analyzed by gas chromatog. coupled to mass spectrometry. This study revealed that oxygenated norditerpenes and diterpenes were one of the major chem. classes (> 50%) mainly consisting of three modified cyclopropylclerodanes containing a bicyclo[5.4.0]undecane ring system: one new furanoid norditerpene, dodovisate C, and two furanoid diterpenes, the known Me dodovisate A and the new Me iso-dodovisate A. These three compounds were isolated by liquid chromatog. and their structures established on the basis of spectroscopic studies. The absolute configuration of dodovisate C was elucidated through a joint exptl. and theor. (B3LYP/6-311+G(d,p)) electronic CD study. The relative configurations of Me dodovisate A and Me iso-dodovisate A were determined using linear regressions of theor. chem. shifts vs. exptl. values with the (B3LYP/6-311+G(d,p)) method. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Recommanded Product: 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Divergent Synthesis of Molecular Winch Prototypes was written by Gisbert, Yohan;Abid, Seifallah;Kammerer, Claire;Rapenne, Gwenael. And the article was included in Chemistry – A European Journal in 2021.Related Products of 41191-92-8 This article mentions the following:

We report the synthesis of conceptually new prototypes of mol. winches [(η⁵-R₄C₅-bp-XTrzR¹)(Ind₃BH)Ru] [R = 4-FcC₆H₄; bp = 1,1′-biphenyl-4,4′-diyl; X = CH₂NHCOCH₂CH₂(OCH₂CH₂)₈; Trz = 1,2,3-triazole-1,4-diyl; R¹ = 9-triptycenyl (tpc), CH₂CH₂OCOC(C₆₀)CO₂Et, 3,5-C₆H₃(CC-9-tpc)₂, 10,20-(CCtpc)₂Por-Zn] with the ultimate aim to investigate the work performed by a single ruthenium-based mol. motor anchored on a surface by probing its ability to pull a load upon elec.-driven directional rotation. According to a technomimetic design, the motor was embedded in a winch structure, with a long flexible polyethylene glycol chain terminated by an azide hook to connect a variety of mol. loads. The structure of the motor was first derivatized by means of two sequential cross-coupling reactions involving a penta(4-halogenophenyl)cyclopentadienyl hydrotris(indazolyl)borate ruthenium(II) precursor and the resulting benzylamine derivative was next exploited as key intermediate in the divergent synthesis of a family of nanowinch prototypes. A one-pot method involving sequential peptide coupling and Cu-catalyzed azide-alkyne cycloaddition was developed to yield four loaded nanowinches, with load fragments encompassing triptycene, fullerene and porphyrin moieties. In the experiment, the researchers used many compounds, for example, Ethyl 3-amino-4-methylbenzoate (cas: 41191-92-8Related Products of 41191-92-8).

Ethyl 3-amino-4-methylbenzoate (cas: 41191-92-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Related Products of 41191-92-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Immunomodulatory Constituents of Conocephalum conicum (Snake Liverwort) and the Relationship of Isolepidozenes to Germacranes and Humulanes was written by Radulovic, Niko S.;Filipovic, Sonja I.;Nesic, Milan S.;Stojanovic, Nikola M.;Mitic, Katarina V.;Mladenovic, Marko Z.;Randjelovic, Vladimir N.. And the article was included in Journal of Natural Products in 2020.Computed Properties of C6H10O2 This article mentions the following:

Structural elucidation of three new sesquiterpenoids, namely, (1Z,4E)-lepidoza-1(10),4-dien-14-ol (I), rel-(1(10)Z,4S,5E,7R)-germacra-1(10),6 diene-11,14-diol (2), and rel-(1(10)Z,4S,5E,7R)-humula-1(10),5-diene-7,14-diol (3), isolated from the liverwort Conocephalum conicum, was accomplished by a combination of extensive NMR experiments, ¹H NMR simulation, and other means. Addnl., the change of the identity of bicyclogermacren-14-al, previously reported as a C. conicum constituent, to isolepidozen-14-al is proposed. Compounds 2 and 3 appear to be related to I via hydration involving a shared intermediate, a substituted cyclopropylmethyl cation, formed by a highly regio- and stereoselective protonation of I, followed by a stereospecific fission of the three-membered ring. In other words, an isolepidozene derivative might be a branchpoint to humulanes and germacranes; this transformation could be of, up to now, unknown, biosynthetic and/or synthetic relevance. Multivariate statistical anal. of the compositional data of C. conicum extract constituents was used to probe the hypothesized biochem. relations. The immunomodulatory effect of I-3 and conocephalenol (4) was evaluated in an in vitro model on both nonstimulated and mitogen-stimulated rat splenocytes. The compounds displayed varying degrees of cytotoxicity to nonstimulated splenocytes, whereas 2 and 3 were found to exert immunosuppressive effects on Con A-stimulated splenocytes while not being cytotoxic at the same concentrations In the experiment, the researchers used many compounds, for example, 5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7Computed Properties of C6H10O2).

5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Computed Properties of C6H10O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dynamic Kinetic Resolution Enabled by Intramolecular Benzoin Reaction: Synthetic Applications and Mechanistic Insights was written by Zhang, Guoxiang;Yang, Shuang;Zhang, Xiaoyan;Lin, Qiqiao;Das, Deb. K.;Liu, Jian;Fang, Xinqiang. And the article was included in Journal of the American Chemical Society in 2016.Related Products of 33166-79-9 This article mentions the following:

The highly enantio-, diastereo-, and regioselective dynamic kinetic resolution of β-ketoesters and 1,3-diketones was achieved via a chiral N-heterocyclic carbene catalyzed intramol. cross-benzoin reaction. A variety of tetralone derivatives bearing two contiguous stereocenters and multiple functionalities were liberated in moderate to excellent yields and with high levels of stereoselectivity (>95% ee and >20:1 dr in most cases). In addition, the excellent regioselectivity control for aryl/alkyl 1,3-diketones, and the superior electronic differentiation of 1,3-diarylketones were highlighted. Moreover, a set of new mechanistic rationale that differs with the currently widely accepted understanding of intramol. benzoin reactions was established to demonstrate the superior preference of benzoin over aldol transformation. A coexistence of competitive aldol and benzoin reactions was detected, but a retro-aldol-irreversible benzoin process performs a vital role in the generation of predominant benzoin products. The most essential role of an N-electron-withdrawing substituent in triazolium catalysts was revealed to be accelerating the rate of the benzoin transformation, rather than suppressing the aldol process through reducing the inherent basicity of the catalyst. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Related Products of 33166-79-9).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Related Products of 33166-79-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Studies on ketene and its derivatives. CX. Synthesis of 1,3-dimethoxyfluoren-9-ones was written by Nakano, Jun;Katagiri, Nobuya;Kato, Tetsuzo. And the article was included in Chemical & Pharmaceutical Bulletin in 1982.Quality Control of Ethyl 3-oxo-3-(m-tolyl)propanoate This article mentions the following:

1,3-Dimethoxyfluoren-9-ones (I; R, R² = H, Me, MeO; R¹ = H; R¹R² = benzo) were prepared from dihydroxybenzoates (II; R = H, R⁴ = EtO) (III). Thus, cyclocondensation of diketene with Et 3-aryl-3-oxopropionates in the presence of NaH in THF gave III, which were treated with MeI followed by alc. NaOH to give II (R³ = Me, R⁴ = HO) (IV). Cyclization of IV with (CF₃CO)₂O gave I. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Quality Control of Ethyl 3-oxo-3-(m-tolyl)propanoate).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Quality Control of Ethyl 3-oxo-3-(m-tolyl)propanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Copper-Catalyzed Cross-Coupling of Thiols, Alcohols, and Oxygen for the Synthesis of Esters was written by Lim, Seungyeon;Ji, Miran;Wang, Xi;Lee, Chan;Jang, Hye-Young. And the article was included in European Journal of Organic Chemistry in 2015.SDS of cas: 27249-90-7 This article mentions the following:

Copper-catalyzed, one-pot, three-component coupling reactions using thiols, alcs., and oxygen to form a variety of esters in good yields were studied. In the presence of easily oxidized benzylic and allylic alcs., thiols were selectively oxidized to form thionoesters, which underwent facile S/O exchange to afford esters. Thiols may be used as an alternative benzoyl source under mild aerobic conditions. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7SDS of cas: 27249-90-7).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.SDS of cas: 27249-90-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kinetic Diastereomer Differentiation in Au(III)- and Bi(III)-Catalyzed Benzylic Arylation: Concise and Stereocontrolled Synthesis of 2-Amino-1,1-diarylalkanes was written by Chenard, Etienne;Hanessian, Stephen. And the article was included in Organic Letters in 2014.Application In Synthesis of (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate This article mentions the following:

2-Nitro- and 2-azido-1,1-diarylalkanes with electron-donating aryl groups such as I [R = 2,4-(MeO)₂C₆H₃, 4-methoxy-1-naphthyl, 4-MeOC₆H₄, 2,3,4-(MeO)₃C₆H₂, 5-methyl-2-furyl, 2,6-(MeO)₂-4-(H₂C:CH)C₆H₂; R¹ = H, Me, Et, n-Pr, i-Pr, allyl, PhCH₂; R² = O₂N, N₃] were prepared diastereoselectively as their syn diastereomers in 14-91% yields (all but one > 50% yields) and in 5:1->20:1 diastereoselectivities by nucleophilic substitution of benzylic alcs. such as I (R = HO; R¹ = H, Me, Et, n-Pr, i-Pr, allyl, PhCH₂; R² = O₂N, N₃) with arenes in the presence of either AuCl₃ or Bi(OTf)₃; an azidotosylamide I (R = TsNH; R¹ = Et; R² = O₂N; Ts = 4-MeC₆H₄SO₂) was prepared using TsNH₂ as a nucleophile instead of an arene. Nonracemic benzyl alcs. were prepared from phenylalanine and incorporated into nonracemic diarylalkyl azides; variation of the aryl group in the nitroalkyl and azidoalkyl benzyl alcs. allowed access in some cases to both syn- and anti-diastereomers of diarylalkyl azido and nitro compounds Kinetic resolution occurred in reactions of diastereomeric mixtures of nitro alcs., with the syn diastereomers of the reactants converted more rapidly to the corresponding products than the anti-diastereomers; both diastereomeric alcs. yielded the syn product. The structure of I (R = 4-MeO-1-naphthyl; R¹ = Et; R² = O₂N) was determined by X-ray crystallog. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Application In Synthesis of (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate).

(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Application In Synthesis of (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Flavor characterization of native Peruvian chili peppers through integrated aroma fingerprinting and pungency profiling was written by Morales-Soriano, Eduardo;Kebede, Biniam;Ugas, Roberto;Grauwet, Tara;Van Loey, Ann;Hendrickx, Marc. And the article was included in Food Research International in 2018.Product Details of 659-70-1 This article mentions the following:

A broad range of Peruvian chili peppers are available but not properly characterized. To increase the insight into their flavor compounds, a head space GC-MS fingerprinting (volatiles) and an HPLC-based profiling approach (pungency) was implemented to characterize twenty landraces (Capsicum annuum, C. baccatum and C. chinense). The data obtained was analyzed with powerful chemometric approaches to identify unique flavor compounds for each of the species and for each of the landraces within a specific species. The pungency profile and volatiles such as esters, terpenes and norcarotenoids distinguish Cerezo triangular (4) (C. annuum). Mainly esters provoked the separation between Chico (42), Cacho de cabra rojo (323), Amarillo de Chachapoyas (318) (C. baccatum), Arnaucho (60) and Miscucho amarillo (69) (C. chinense). This study demonstrates the potential of the integrated fingerprinting, profiling and a chemometric approach to extensively understand the unique flavor compounds in Peruvian chili peppers. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Product Details of 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Product Details of 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Comparative metabolome classification of desert truffles Terfezia claveryi and Terfezia boudieri via its aroma and nutrients profile was written by Farag, Mohamed A.;Fathi, Doaa;Shamma, Samir;Shawkat, Mohamed Sherif A.;Shalabi, Sohir M.;El Seedi, Hesham R.;Afifi, Sherif M.. And the article was included in LWT–Food Science and Technology in 2021.Category: esters-buliding-blocks This article mentions the following:

Desert truffles are popular ectomycorrhizal fungi valued worldwide for their nutritional and traditional health benefits. Herein, two chief desert truffles viz., Terfezia claveryi and T. boudieri were assessed for their metabolites heterogeneity in context of their volatile sensory and nutrients profile as analyzed via GC-MS. Primary metabolites accounting for nutritive indexes in T. claveryi and T. boudieri were investigated with 61 peaks belonging to sugars, sugar alcs. and amino acids. After headspace solid-phase microextraction (HS-SPME), a total of 106 volatiles were annotated belonging to alcs., ketones, aldehydes, esters, ethers and furans. The abundance of oxygenated monoterpenes as antimicrobials rationalizes for the folk use of desert truffles against trachoma. Benzyl isothiocyanate was detected as the sulfur containing volatile component in desert truffle and absent from truffles. Multivariate data analyses (MVA) revealed that 1-octen-3-ol and 3-octanone were the most significantly contributors in the discrimination of T. claveryi and T. boudieri specimens. Being more enriched in essential amino acids, T. claveryi provided a better sugar diet composition concurrent with lower sugars and higher sugar alcs. compared to T. boudieri. This study provides the first insight into desert truffles metabolites and sensory composition, and to account for its culinary and medicinal uses. In the experiment, the researchers used many compounds, for example, 5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7Category: esters-buliding-blocks).

5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Reaction of alkyl malonates with nitric acid was written by Glowczyk, Joanna;Lange, Jerzy;Abramski, Jan W.. And the article was included in Roczniki Chemii in 1977.Product Details of 10203-58-4 This article mentions the following:

The title reaction with fuming HNO₃ gave RC(NO₂)(CO₂Et)₂ (I; R = Me, Et, Me₂CH, Bu, Me₂CHCH₂, Me₃C) and RC(OH)(CO₂Et)₂ (II); the ratio I–II depended on the temperature At low temperature II was favored and at high temperature I was favored. The degree of conversion depended on R. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Product Details of 10203-58-4).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Product Details of 10203-58-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics