Category: esters-buliding-blocks

Polystyrene/sepiolites nanocomposite foams: Relationship between composition, particle dispersion, extensional rheology, and cellular structure was written by Ballesteros, A.;Laguna-Gutierrez, E.;Puertas, M. L.;Esteban-Cubillo, A.;Santaren, J.;Rodriguez-Perez, M. A.. And the article was included in Materials Today Communications in 2021.Electric Literature of C73H108O12 This article mentions the following:

The main objective of this work is to analyze how the cellular structure of foamed polystyrene based (PS) nanocomposites, produced by gas dissolution foaming, is affected by the extensional rheol. behavior of the polymer matrix and by the dispersion degree of the particles. These composites have been produced with different types of natural and organomodified sepiolites and with different contents of these particles. The extensional behavior and the dispersion degree were characterized by extensional and shear dynamic rheol. resp. The results obtained indicate that the extensional rheol. behavior controls the foam degeneration mechanisms; meanwhile, the way in which the particles are dispersed in the PS matrix controls the nucleation mechanisms. Results also indicate that, in these systems, the characteristics of the cellular structure are mainly defined by the way in which nucleation occurs. Therefore, improving the dispersion degree is a key approach to reduce the cell size by 90%, with respect to the pure polymer. In the experiment, the researchers used many compounds, for example, 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8Electric Literature of C73H108O12).

2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C73H108O12

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rhodium(I)-catalyzed vinylation/[2+1] carbocyclization of 1,6-enynes with α-diazocarbonyl compounds was written by Huang, Junmin;Hu, Xinwei;Chen, Fengjuan;Gui, Jiao;Zeng, Wei. And the article was included in Organic & Biomolecular Chemistry in 2019.HPLC of Formula: 13669-10-8 This article mentions the following:

A sequential Rh(I)-catalyzed vinylation/[2+1]carbocyclization between enynes and diazo compounds has been developed. This transformation features a wide range of enynes and acceptor/acceptor diazo compounds, providing easy access to versatile vinyl-substituted azabicyclo[3.1.0]hexanes having a broad tolerance to functional groups. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8HPLC of Formula: 13669-10-8).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.HPLC of Formula: 13669-10-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Depolymerization mechanism of alkali lignin in sub- and supercritical ethanol was written by Chen, Meng-wei;Guo, Da-liang;Wang, Lin-fang;Xue, Guo-xin. And the article was included in Ranliao Huaxue Xuebao in 2016.Safety of Dimethyl decanedioate This article mentions the following:

The depolymerization process of wheat straw alkali lignin in sub- and supercritical ethanol was investigated with a micro autoclave reactor. The degraded product properties and the depolymerization mechanism of lignin structure were studied by SEM (SEM), gas chromatog./mass spectrometry (GC/MS) and IR spectroscopy (FT-IR). The exptl. results showed that the min. residual char yield (16.5%) was obtained at the condition of ethanol supercritical point (240°C, 7.2 MPa). Under subcritical ethanol conditions, alkali lignin firstly melted and dispersed in ethanol as 1.0-2.0 μm diameter of microspheres, then a small amount of ether linkages and benzene ring side chain C_α were broken to form phenols, esters, ketones and acids products. Under supercritical ethanol conditions, the diameter of molten microsphere was significantly reduced, and plenty of ether linkages and benzene ring side chain C_α were continuously broken, meanwhile, the lipid products were subjected to secondary decomposition reaction. The yield of lipid was decreased (11.94%), while the yield of phenolic products from depolymerization was increased (52.14%). In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Safety of Dimethyl decanedioate).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Safety of Dimethyl decanedioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bronsted Acid/Silane Catalytic System for Intramolecular Hydroalkoxylation and Hydroamination of Unactivated Alkynes was written by Shibuya, Masatoshi;Fujita, Shoji;Abe, Masanori;Yamamoto, Yoshihiko. And the article was included in ACS Catalysis in 2017.Category: esters-buliding-blocks This article mentions the following:

The Bronsted acid-catalyzed intramol. hydroalkoxylation and hydroamination of unactivated alkynes are described. We found that unactivated alkynes are electrophilically activated by a catalytic amount of bis(trifluoromethanesulfonyl)imide to undergo intramol. hydroalkoxylation and hydroamination. In the presence of silane Et₃SiH, the formed reactive exo-cyclic enol ether and exo-cyclic enamine intermediates are effectively reduced to the corresponding saturated cyclic ethers and N-protected cyclic amines. The 2,4-cis and 2,5-cis pyrrolidine derivatives are produced with high diastereoselectivity. Taking advantage of this selectivity, the 2,5-cis-disubstituted prolinol was also synthesized from glutamic acid in the optically active form. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Category: esters-buliding-blocks).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Difluoro ketone peptidomimetics suggest a large s1 pocket for Alzheimer’s γ-secretase: implications for inhibitor design was written by Moore, Chad L.;Leatherwood, Dartha D.;Diehl, Thekla S.;Selkoe, Dennis J.;Wolfe, Michael S.. And the article was included in Journal of Medicinal Chemistry in 2000.Reference of 87694-53-9 This article mentions the following:

The final step in the generation of the amyloid-β protein (Aβ), implicated in the etiol. of Alzheimer’s disease, is proteolysis within the transmembrane region of the amyloid precursor protein (APP) by γ-secretase. Although considered an important target for therapeutic design, γ-secretase has been neither well-characterized nor definitively identified. Previous studies in our laboratory using substrate-based difluoro ketone and difluoro alc. transition-state analog inhibitors suggest that γ-secretase is an aspartyl protease with loose sequence specificity. To further characterize the active site of γ-secretase, we prepared a series of difluoro ketone peptide analogs with varying steric bulkiness in the P1 position and tested the ability of these compounds to inhibit Aβ production in APP-transfected cells. Incorporation of bulky, aliphatic P1 side chains, such as sec-Bu or cyclohexylmethyl, led to increased γ-secretase inhibitory potency, suggesting a large S1 pocket to accommodate these substituents and providing further evidence for loose sequence specificity. The cyclohexylmethyl P1 substituent allowed N-terminal truncation to a low-mol.-weight compound (<600 Da) that effectively blocked Aβ production (IC₅₀ âˆ?5 μM). This finding suggests that optimal S1 binding may allow the development of potent inhibitors with ideal pharmaceutical properties. Moreover, a difluoro alc. analog with a cyclohexylmethyl P1 substituent was equipotent with its difluoro ketone counterpart, providing strong evidence that γ-secretase is an aspartyl protease. All new analogs inhibited total Aβ and Aβ₄₂ production with the same rank order of potency and increased Aβ₄₂ production at low concentrations, providing further evidence for distinct γ-secretases that are nevertheless closely similar with respect to active site topol. and mechanism. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Reference of 87694-53-9).

(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Reference of 87694-53-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bioherbicide Potential of Eucalyptus saligna Leaf Litter Essential Oil was written by Silva, Eliane R.;Igartuburu, Jose M.;Overbeck, Gerhard E.;Soares, Geraldo L. G.;Macias, Francisco A.. And the article was included in Chemistry & Biodiversity in 2020.Related Products of 659-70-1 This article mentions the following:

We aimed to evaluate the bioherbicide potential of Eucalyptus saligna leaf litter essential oil, its fractions and major compounds Six essential oil fractions were obtained by preparative thin-layer chromatog. and analyzed by gas chromatog./mass spectrometry. Effects of the oil, its fractions and major compounds (1,8-cineole and/or α-pinene) diluted in aqueous solution were assessed on germination and seedling growth. Recipient species were Lactuca sativa (model), Amaranthus viridis (weed), Eragrostis plana (weed), and Paspalum notatum (forage). The essential oil was more phytotoxic on A. viridis and L. sativa, followed by E. plana, and caused no effects on P. notatum. Amaranthus viridis was inhibited by all treatments, mainly the essential oil, α-pinene and fraction 6, whereas E. plana was more affected by the oil fractions. Results revealed the species-specific phytotoxic effects of E. saligna essential oil, indicating its potential use for controlling A. viridis and E. plana. Phytotoxic effects of essential oils or their components should not be generalized, as effects may change according to recipient species. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Related Products of 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Related Products of 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity was written by Travelli, Cristina;Aprile, Silvio;Rahimian, Reza;Grolla, Ambra A.;Rogati, Federica;Bertolotti, Mattia;Malagnino, Floriana;di Paola, Rosanna;Impellizzeri, Daniela;Fusco, Roberta;Mercalli, Valentina;Massarotti, Alberto;Stortini, Giorgio;Terrazzino, Salvatore;Del Grosso, Erika;Fakhfouri, Gohar;Troiani, Maria Pia;Alisi, Maria Alessandra;Grosa, Giorgio;Sorba, Giovanni;Canonico, Pier Luigi;Orsomando, Giuseppe;Cuzzocrea, Salvatore;Genazzani, Armando A.;Galli, Ubaldina;Tron, Gian Cesare. And the article was included in Journal of Medicinal Chemistry in 2017.Recommanded Product: Methyl 2-(4-(hydroxymethyl)phenyl)acetate This article mentions the following:

Nicotinamide phosphoribosyltransferase (NAMPT) is a key enzyme involved in the recycling of nicotinamide to maintain adequate NAD levels inside the cells. It has been postulated to be a pharmacol. target, as it is overexpressed in cancer cells as well as in inflammatory diseases. We describe the synthesis and characterization of a novel class of one-digit nanomolar NAMPT inhibitors based on in vitro characterization. The most active compound tested, I, displayed activity in xenograft and allograft models, strengthening the potential of NAMPT inhibitors as antitumoral drugs. Furthermore, in the present contribution we describe the ability of I to significantly improve the outcome of colitis in mice. Given that this is the first report of an effect of NAMPT inhibitors in colitis, this result paves the way for novel applications for this class of compounds In the experiment, the researchers used many compounds, for example, Methyl 2-(4-(hydroxymethyl)phenyl)acetate (cas: 155380-11-3Recommanded Product: Methyl 2-(4-(hydroxymethyl)phenyl)acetate).

Methyl 2-(4-(hydroxymethyl)phenyl)acetate (cas: 155380-11-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: Methyl 2-(4-(hydroxymethyl)phenyl)acetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of biocharcoal aerogel sorbent for solid-phase microextraction of polycyclic aromatic hydrocarbons in water samples was written by Ji, Xiangping;Feng, Juanjuan;Li, Chunying;Han, Sen;Sun, Min;Feng, Jiaqing;Sun, Haili;Fan, Jing;Guo, Wenjuan. And the article was included in Journal of Separation Science in 2020.Quality Control of Dicyclohexyl phthalate This article mentions the following:

A facile method was introduced for preparing a biocharcoal aerogel, which was derived from pomelo peel as the only raw material. The inner spongy layer of pomelo peel was freeze-dried for maintaining three-dimensional structure and then carbonized under high temperature and oxygen-limited conditions. The morphol. structure and graphitization degree of biocharcoal aerogel were characterized using a scanning electron microscope and Raman spectrum. After sifting and grinding, the biocharcoal aerogel as an adsorbent was coated onto the surface of stainless steel wires. Through placing the wires into a polyetheretherketone tube, the in-tube solid-phase microextraction device was obtained. Coupled with high-performance liquid chromatog., it exhibited good extraction performance for polycyclic aromatic hydrocarbons, then an online anal. method was established with low limits of detection (0.005-0.050 ng/mL), wide linear ranges (0.017-15 ng/mL) with superior correlation coefficients higher than 0.9990, high enrichment factors (1128-3425), and acceptable intra- and inter-day repeatabilities (relative standard deviations �6.7%, n = 3). The method was applied to detect polycyclic aromatic hydrocarbons in bottled water samples, environmental water samples, and soft drinks with satisfactory recoveries (83.3-120.9%). This research not only developed a new carbon aerogel but also evaluated its adsorption performance in sample preparation In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Quality Control of Dicyclohexyl phthalate).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Quality Control of Dicyclohexyl phthalate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Design of multi-phase dynamic chemical networks was written by Chen, Chenrui;Tan, Junjun;Hsieh, Ming-Chien;Pan, Ting;Goodwin, Jay T.;Mehta, Anil K.;Grover, Martha A.;Lynn, David G.. And the article was included in Nature Chemistry in 2017.Application In Synthesis of (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate This article mentions the following:

Template-directed polymerization reactions enable the accurate storage and processing of nature’s biopolymer information. This mutualistic relationship of nucleic acids and proteins, a network known as life’s central dogma, is now marvelously complex, and the progressive steps necessary for creating the initial sequence and chain-length-specific polymer templates are lost to time. Here we design and construct dynamic polymerization networks that exploit metastable prion cross-β phases. Mixed-phase environments have been used for constructing synthetic polymers, but these dynamic phases emerge naturally from the growing peptide oligomers and create environments suitable both to nucleate assembly and select for ordered templates. The resulting templates direct the amplification of a phase containing only chain-length-specific peptide-like oligomers. Such multi-phase biopolymer dynamics reveal pathways for the emergence, self-selection and amplification of chain-length- and possibly sequence-specific biopolymers. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Application In Synthesis of (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate).

(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application In Synthesis of (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Photocatalytic Hydromethylation and Hydroalkylation of Olefins Enabled by Titanium Dioxide Mediated Decarboxylation was written by Zhu, Qilei;Nocera, Daniel G.. And the article was included in Journal of the American Chemical Society in 2020.HPLC of Formula: 868-57-5 This article mentions the following:

A versatile method for the hydromethylation and hydroalkylation of alkenes at room temperature is achieved by using the photooxidative redox capacity of the valence band of anatase titanium dioxide (TiO₂). Mechanistic studies support a radical-based mechanism involving the photoexcitation of TiO₂ with 390 nm light in the presence of acetic acid and other carboxylic acids to generate Me and alkyl radicals, resp., without the need for stoichiometric base. This protocol is accepting of a broad scope of alkene and carboxylic acids, including challenging ones that produce highly reactive primary alkyl radicals and those containing functional groups that are susceptible to nucleophilic substitution such as alkyl halides. This methodol. highlights the utility of using heterogeneous semiconductor photocatalysts such as TiO₂ for promoting challenging organic syntheses that rely on highly reactive intermediates. In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5HPLC of Formula: 868-57-5).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.HPLC of Formula: 868-57-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics