Category: esters-buliding-blocks

Characterization of odor-active volatile compounds of jambolan [Syzgium cumini (L.) Skeels] wine was written by Pino, Jorge A.;Espinosa, Sixsy;Duarte, Cira. And the article was included in Journal of Food Science and Technology (New Delhi, India) in 2022.Computed Properties of C10H20O2 This article mentions the following:

Volatile constituents in jambolan [Syzgium cumini (L.) Skeels] wine were isolated by headspace-solid phase microextraction (HS-SPME) and analyzed by gas chromatog.-flame ionization detector (GC-FID), gas chromatog.-mass spectrometry (GC-MS), and gas chromatog.-olfactometry (GC-O). The composition of the jambolan wine included 52 esters, 20 terpenes, 13 alcs., 12 acids, 11 aldehydes, 4 ketones, 4 oxides, and 5 miscellaneous compounds Aroma extract dilution anal. and odor activity units were used for the determination of odor-active compounds A total of 19 odor-active compounds were found as odor-active volatiles, from which (E)-β-ionone, phenylacetaldehyde, Et acetate, Et hexanoate, and Et benzoate were the most important. The similar results of the GC-O and OAV approaches suggests that HS-SPME-GC-O could be used as a fast and simple tool to quality control of the jambolan wine aroma. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Computed Properties of C10H20O2).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Computed Properties of C10H20O2

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and cytotoxic activity of 4-O-β-D-galactopyranosyl derivatives of phenolic acids esters was written by Al Bujuq, Nader;Arar, Sharif;Khalil, Raida. And the article was included in Natural Product Research in 2018.Safety of (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate This article mentions the following:

The glycosylation of naturally occurring phenolic acids has a significant impact on their solubility, stability and physiochem. properties. D-Galactose residue was found to form a part of glycoconjugates in several tissues and involved in a variety of physiol. process. To the best of our knowledge, we have noticed a little information about the glycosylation of the phenolic acids with galactose residue. In this work, we describe the glycosylation of Me vanillate and Me ferulate with peracetylated-β-D-galactopyranose in the presence of BF₃·OEt₂. The coupling reaction yielded efficiently and selectively only the acetylated β-D-galactopyranosides and . Removal of the acetyl groups using sodium methoxide afforded the corresponding β-D-galactopyranosides and in good yields. Anticancer activity in vitro was evaluated against two human cancer cell lines (MCF-7 breast cancer cell lines and PC-3 prostate cancer cell lines). β-D-galactopyranosides and demonstrated improved cytotoxic activity compared to the parental esters. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4Safety of (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Safety of (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Characterization of key odor-active compounds in commercial high-salt liquid-state soy sauce by switchable GC/GC x GC-olfactometry-MS and sensory evaluation was written by Wang, Xiaojun;Guo, Mengyao;Song, Huanlu;Meng, Qi;Guan, Xiaosheng. And the article was included in Food Chemistry in 2021.Application In Synthesis of 5-Hexyldihydrofuran-2(3H)-one This article mentions the following:

Activity of odor compounds of soy sauces has not been fully determined so far. Herein, a new switchable GC/GC x GC-olfactometry-mass spectrometry system for simultaneous GC x GC-MS anal. and sniffing of each odor-active substance through a single injection was used for the aroma extract dilution anal. of five regular high-salt liquid-state soy sauces (HLS). Methional, maltol, guaiacol, 4-ethylguaiacol, 2-acetylpyrrole, 2-acetylfuran, 2-phenylethanol, and 4-hydroxy-2,5-dimethyl-3(2H)-furanone showed high flavor dilution (FD) factors. The FD factors of all odor-active compounds in different odor attributes were summed up (score) to evaluate the odor characteristics of the samples. Cooked potato-like odor was the most important characteristic. The difference in the odor characteristics were mainly reflected in the balance of caramel-like/sweet, roasted/roasted nut-like, spicy/burnt, and unpleasant odor intensity; the fruity odor intensity was the weakest. This study will provide a better understanding of the odor characteristics and key odor-active compounds in Chinese regular com. HLS. In the experiment, the researchers used many compounds, for example, 5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9Application In Synthesis of 5-Hexyldihydrofuran-2(3H)-one).

5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Application In Synthesis of 5-Hexyldihydrofuran-2(3H)-one

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Combination of epigallocatechin gallate with L-cysteine in inhibiting Maillard browning of concentrated orange juice during storage was written by Chen, Yangyang;Zhang, Min;Mujumdar, Arun S.;Liu, Yaping. And the article was included in LWT–Food Science and Technology in 2022.Safety of (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate This article mentions the following:

Orange juice is popular with consumers because of its unique taste, flavor as well as nutritional value which accounts for a large proportion of the global juice market. Concentrated orange juice (COJ), undergoes browning during storage seriously affecting its quality and com. This study was the first to evaluate the effects of epigallocatechin gallate (EGCG) and L-cysteine (L-cys) on Maillard browning of COJ during storage. The results show that EGCG and L-cys reduce significantly the production of 5-hydroxymethylfurfural (5-HMF), the characteristic product of Maillard reaction (MR), and the combined use of EGCG and L-cys was even more effective. Furthermore, the color of the treated COJ displayed negligible change after storage, with higher L* and b* values and marginally lower a* values. The flavor, taste, main volatile substances as well as rheol. properties of the treated COJ were also determined; none of these properties were affected adversely during storage. This treatment method ensures that the key sensory quality and material properties of COJ are preserved by the proposed treatment while inhibiting Maillard browning during storage. In the experiment, the researchers used many compounds, for example, (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3Safety of (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate).

(E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Safety of (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Optically active γ-hydroxy sulfone Julia reagents for the synthesis of peptidyl olefin peptidomimetics was written by Mirilashvili, Sima;Chasid-Rubinstein, Naama;Albeck, Amnon. And the article was included in European Journal of Organic Chemistry in 2008.Recommanded Product: 10203-58-4 This article mentions the following:

Peptidyl olefin peptidomimetics serve as biol. active compounds or as intermediates for other peptidyl isosteres. We developed a chemoenzymic stereoselective approach to optically active γ-hydroxy sulfones to be assembled into peptidyl olefins by the Julia reaction. Key enzymic hydrolysis of prochiral diesters to the corresponding hydroxy esters introduces optical activity. The sequence of the subsequent chem. reactions, either protection-hydrolysis-functionalization or functionalization-hydrolysis-protection, determines the absolute stereochem. of the final sulfone building block. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Recommanded Product: 10203-58-4).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: 10203-58-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effects of different exaction methods on constituents of volatile oil from Idesia polycarpa maxim was written by Ye, Yang;Wang, Xiao-meng;Bu, Gui-xian;Xiao, Ping;Chen, Fang;Tang, Lin. And the article was included in Sichuan Daxue Xuebao, Ziran Kexueban in 2013.Related Products of 106-79-6 This article mentions the following:

The volatile oils of Idesia polycarpa Maxim fruits were extracted by different methods such as steam distillation, ultrasonic and Soxhlet extraction The chem. compounds were separated and identified by capillary GC-MS method. The relative content of each component was calculated by area normalization. 64, 50 And 57 volatile components as listed in Table 1 were identified, and 38 components were owned by all. The main components are linoleic acid, palmitic acid, oleic acid, squalene, γ-nonalactone and γ-Tocopherol etc. The components extracted by steam distillation were much more compared with other methods, while the extract rate by Soxhlet extraction was the highest. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Related Products of 106-79-6).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Related Products of 106-79-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and Antileukemia Activity Evaluation of Benzophenanthridine Alkaloid Derivatives was written by Tang, Yaling;Xu, Xinglian;Li, Jiang;Deng, Lulu;Mu, Shuzhen. And the article was included in Molecules in 2022.Reference of 1190-39-2 This article mentions the following:

Thirty_–three benzophenanthridine alkaloid derivatives (1a_–1u and 2a_–2l) were synthesized, and their cytotoxic activities against two leukemia cell lines (Jurkat Clone E6_–1 and THP_–1) were evaluated in vitro using a Cell Counting Kit_–8 (CCK_–8) assay. Nine of these derivatives (1i_–l, 2a, and 2i_–l) with IC₅₀ values in the range of 0.18_–7.94 μM showed significant inhibitory effects on the proliferation of both cancer cell lines. Anal. of the primary structure_–activity relationships revealed that different substituent groups at the C_–6 position might have an effect on the antileukemia activity of the corresponding compounds In addition, the groups at the C_–7 and C_–8 positions could influence the antileukemia activity. Among these compounds, 2j showed the strongest in vitro antiproliferative activity against Jurkat Clone E6_–1 and THP_–1 cells with good IC50 values (0.52 ± 0.03 μM and 0.48 ± 0.03 μM, resp.), slightly induced apoptosis, and arrested the cell-cycle, all of which suggests that compound 2j may represent a potentially useful start point to undergo further optimization toward a lead compound In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Reference of 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Reference of 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Certified Reference Material for the Quantification of Phthalates in Polyvinyl Chloride Resin (NMIJ CRM 8152) was written by Hanari, Nobuyasu;Orihara, Yukari;Matsuyama, Shigetomo. And the article was included in Analytical Letters in 2021.Formula: C20H26O4 This article mentions the following:

Phthalates are primary industrial chems. used as polyvinyl chloride (PVC) plasticizers. However, certain phthalates are controlled as restricted substances listed under Annex II of Directive 2011/65/EU, (EU)2015/863. Since an accurate quantification of phthalates is essential to monitoring their concentration levels, quality assurance during their analyses using certified reference materials (CRMs) is required. A PVC CRM for the quantification of phthalates (NMIJ CRM 8152) was provided by the National Metrol. Institute of Japan. This CRM was in the form of grayish-white pellets (3-mm diameter x 3-mm length). The anal. procedures adopted were isotope-dilution mass spectrometry, which was the primary method of measurement, and gas chromatog./mass spectrometry; these procedures were optimized and applied to the characterization. The mass fractions of five target phthalates calculated using the mean values were determined as the certified values of the CRM. The relative standard uncertainties attributed to the certification were combined, e.g., those for the characterization, inhomogeneity, and instability. The mass fractions of five phthalates were certified, and those of three phthalates and one adipate were acquired and are reported as tech. information. The CRM is shown to be applicable to assessing the validity of anal. methods during the quantification of phthalates in PVC resin and similar materials. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Formula: C20H26O4).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Formula: C20H26O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of adamantane derivatives with potential antiviral activity was written by Arya, V. P.;Fernandes, F.;Ghate, S. P.;Costa-Pereira, F. X. R.;Wasaiwalla, Y. H.. And the article was included in Indian Journal of Chemistry in 1972.Electric Literature of C8H6FNS This article mentions the following:

Adamantane derivatives (I; R = e.g., NHEt, NHSO2NMe2, NHCH2(NH2)C:NOH, NHCSNHR1, R1 = e.g., allyl, CMe3, CH2C6H4F-p; CONH(CH2)3R2, R2 = e.g., piperidino, morpholino, 4-methyl-1-piperazinyl) were prepared by treating I (R = NH2) with isothiocyanates, isocyanates and Me2NSO2NHCl. Some 1-(alkylamino)adamantanes and substituted adamantane-1-carboxamides were also prepared Antiviral activity of these compounds against influenza PR3 virus was described. In the experiment, the researchers used many compounds, for example, 4-Fluorobenzylisothiocyanate (cas: 2740-88-7Electric Literature of C8H6FNS).

4-Fluorobenzylisothiocyanate (cas: 2740-88-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Electric Literature of C8H6FNS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The hydrolysis of carboxylic anhydrides. IV. Succinic and tetramethylsuccinic anhydrides was written by Bunton, C. A.;Fendler, J. H.;Fuller, N. A.;Perry, S.;Rocek, J.. And the article was included in Journal of the Chemical Society in 1963.Electric Literature of C10H11FO2 This article mentions the following:

Hydrolysis of succinic and tetramethylsuccinic anhydride is retarded by aqueous mineral acids (except for dilute H₂SO₄ and HCl). It is acid-catalyzed in aqueous dioxane. Hydrolysis of succinic anhydride in water is accelerated by bivalent electrolytes, but retarded by univalent electrolytes (except for NaHSO₄). In water the feeble catalysis by protons is opposed by a sp. neg. salt effect, but the rate in aqueous acid is always greater than that in solutions of the alkali-metal salts. In the experiment, the researchers used many compounds, for example, Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2Electric Literature of C10H11FO2).

Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Electric Literature of C10H11FO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics