Category: esters-buliding-blocks

An Immunoassay To Evaluate Human/Environmental Exposure to the Antimicrobial Triclocarban was written by Ahn, Ki Chang;Kasagami, Takeo;Tsai, Hsing-Ju;Schebb, Nils Helge;Ogunyoku, Temitope;Gee, Shirley J.;Young, Thomas M.;Hammock, Bruce D.. And the article was included in Environmental Science & Technology in 2012.Quality Control of Methyl 4-(4-aminophenyl)butanoate This article mentions the following:

A sensitive, competitive indirect ELISA for the detection of the antimicrobial triclocarban (TCC) was developed. The haptens were synthesized by derivatizing the para position of a Ph moiety of TCC. The rabbit antisera were screened and the combination of antiserum 1648 and a heterologous competitive hapten containing a piperidine was further characterized. The IC₅₀ and detection range for TCC in buffer were 0.70 and 0.13-3.60 ng/mL, resp. The assay was selective for TCC, providing only low cross-reactivity to TCC-related compounds and its major metabolites except for the closely related antimicrobial 3-trifluoromethyl-4,4′-dichlorocarbanilide. A liquid-liquid extraction for sample preparation of human body fluids resulted in an assay that measured low part per billion levels of TCC in small volumes of the samples. The limits of quantification of TCC were 5 ng/mL in blood/serum and 10 ng/mL in urine, resp. TCC in human urine was largely the N- or N’-glucuronide. TCC concentrations of biosolids measured by the ELISA were similar to those determined by LC-MS/MS. This immunoassay can be used as a rapid, inexpensive, and convenient tool to aid researchers monitoring human/environmental exposure to TCC to better understand the health effects. In the experiment, the researchers used many compounds, for example, Methyl 4-(4-aminophenyl)butanoate (cas: 20637-09-6Quality Control of Methyl 4-(4-aminophenyl)butanoate).

Methyl 4-(4-aminophenyl)butanoate (cas: 20637-09-6) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Quality Control of Methyl 4-(4-aminophenyl)butanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Environmental implications from the priority pollutants screening in impoundment reservoir along the eastern route of China′s South-to-North Water Diversion Project was written by Zhao, Zhonghua;Gong, Xionghu;Ding, Qiqi;Jin, Miao;Wang, Zhaode;Lu, Shaoyong;Zhang, Lu. And the article was included in Science of the Total Environment in 2021.SDS of cas: 84-61-7 This article mentions the following:

Screening priority pollutants from vast anthropogenic contaminants discharged into aquatic environment is urgent for protecting water quality definitely. The multi-criteria scoring method involved in the occurrence (O), persistence (P), bioaccumulation (B), ecol. risk (Eco-T), and human health risk (Hum-T), was established for pollutants prioritization in waters and applied in Dongping Lake, the final impoundment reservoir along the eastern route of China′s South-to-North Water Diversion Project (SNWDP). A total of 170 chems. including heavy metals (HMs), volatile organic chems. (VOCs), polycyclic aromatic hydrocarbons (PAHs), organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), phthalate esters (PAEs), and antibiotics (ANTs) were investigated as the candidates. Accordingly, 42 chems. including 8 PAEs, 7 OCPs, 7 PCBs, 5 PAHs, 13 HMs, and 2 VOCs were made up the list of priority pollutants for Dongping Lake, suggesting the necessity of routine monitoring high priority groups and revising the existing list. Multiple risk assessment indicated higher ecol. and human health risks induced by HMs than by organic pollutants. Spatial distribution of risks stressed the retention of toxic organic chems. by the lake body and the accumulation of HMs along the transfer route, resp., thus triggering ecosystem responses and potential effects on the water-receiving areas as expected. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7SDS of cas: 84-61-7).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.SDS of cas: 84-61-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Trace analysis of multiple synthetic phenolic antioxidants in foods by liquid chromatography-tandem mass spectrometry with complementary use of electrospray ionization and atmospheric pressure chemical ionization was written by Du, Bibai;Shen, Mingjie;Pan, Zibin;Zhu, Chunyou;Luo, Dan;Zeng, Lixi. And the article was included in Food Chemistry in 2022.Name: 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) This article mentions the following:

This study presented a universal LC-MS/MS method for trace anal. of multiple synthetic phenolic antioxidants (SPAs) in foods by complementary use of electrospray ionization (ESI) and atm. pressure chem. ionization (APCI). The analytes included not only the well-known BHT and BHA but also 18 high mol. weight SPAs. The method utilized APCI to achieve sensitive anal. of BHT, Irganox 1010, Irganox 330, and Irganox 3125 based on the finding that APCI significantly improved the sensitivity of these weakly acidic or slightly polar SPAs, and utilized ESI to obtain sensitive anal. of other SPAs. Addnl., the method avoided background contamination by using effective measures including installation of a trapping column in the LC system. Method performance assessment showed satisfactory sensitivity, linearity, accuracy, and precision for anal. of SPAs in vegetable oil, milk powder, and baby fruit puree. Method application revealed widespread contamination of foods with BHT, Irganox 1010, and Irganox 1076. In the experiment, the researchers used many compounds, for example, 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8Name: 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate)).

2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Name: 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis, DNA binding, topoisomerases inhibition, and cytotoxic properties of 4-arylcarboxamidopyrrolo-2-carboxyanilides was written by Dudouit, Fabienne;Goossens, Jean-Francois;Houssin, Raymond;Henichart, Jean-Pierre;Colson, Pierre;Houssier, Claude;Gelus, Nathalie;Bailly, Christian. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2000.Application of 5930-92-7 This article mentions the following:

N-aryl-4-benzamidopyrrolecarboxamides I (R = H, Me, PhCH₂) were synthesized and evaluated for their capacities to bind to specific sequences within the minor groove of DNA and to inhibit human topoisomerases I and II in vitro. The cytotoxicity of the drugs correlates with their DNA binding affinities. Compounds I (R = Me, PhCH₂) stabilize topoisomerase I-DNA complexes. In the experiment, the researchers used many compounds, for example, Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7Application of 5930-92-7).

Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application of 5930-92-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and evaluation of phospholipid analogs as inhibitors of cobra venom phospholipase A₂ was written by Yuan, Wei;Berman, Richard J.;Gelb, Michael H.. And the article was included in Journal of the American Chemical Society in 1987.Name: Ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate This article mentions the following:

Analogs of phospholipids that contain fluoro ketone, ketone, and alc. replacements for the ester at the 2-position of the glycerol backbone were prepared and analyzed as inhibitors of phospholipase A₂ from Naja naja naja venom. Phospholipid analogs were studied that contain two alkyl chains, e.g., I as well as single chain compounds, e.g., II that lack C(1) of the glycerol backbone and the attached acyl unit. Compounds that contain both long and medium length alkyl chains were studied. All of the potential inhibitors were tested in a well-defined mixed micelle system in which both the substrates and the inhibitors were incorporated into Triton X-100 micelles. The best inhibitors studied were the single chain fluoro ketones despite the fact that the enzyme has a strong preference for two-chain lipids. The most potent compound was found to have a dissociation constant some 1000-3000-fold lower than the Michaelis constant for dipalmitoyl phosphatidylcholine substrate. ¹⁹F-NMR studies of the fluoro ketone phospholipid analogs in micelles show that whereas the single chain compounds are partially in the hydrated-ketone form, the two-chain compounds are less than 0.1% hydrated. In every case studied, potent inhibition of phospholipase A₂ was observed only with those compounds that are significantly hydrated in the micelle, and it is suggested that the hydrated fluoro ketone containing phospholipid analogs are the species responsible for the inhibition. In addition, the single chain fluoro ketones were better inhibitors than single and double chain alc. and ketone analogs. Previous studies have shown that the cobra venom enzyme is activated by choline-containing lipids, and evidence is presented for the binding of the hydrated fluoro ketone inhibitors selectively to the activated enzyme. In the experiment, the researchers used many compounds, for example, Ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate (cas: 82962-54-7Name: Ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate).

Ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate (cas: 82962-54-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Name: Ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Controlled free-radical copolymerization of maleic anhydride and divinyl ether in the presence of reversible addition-fragmentation chain-transfer agents¹ was written by Serbin, A. V.;Karaseva, E. N.;Dunaeva, I. V.;Krut’ko, E. B.;Talyzenkov, Yu. A.;Filatova, M. P.;Chernikova, E. V.. And the article was included in Polymer Science, Series B in 2011.COA of Formula: C14H12S2 This article mentions the following:

The free-radical alternating cyclocopolymn. of maleic anhydride and divinyl ether is studied at 60-80° in the presence of benzyl dithiobenzoate and dibenzyl trithiocarbonate as reversible addition-fragmentation chain-transfer agents. The structure of the repeating unit of the cyclocopolymer prepared in the presence of a reversible addition-fragmentation chain-transfer agent coincides with the structure of the repeating unit of the copolymer synthesized under the conditions of conventional free-radical cyclocopolymn. When the cyclocopolymer is used as a reversible addition-fragmentation chain transfer agent, a successive increase in the mol. mass of the copolymer with conversion and formation of the block copolymer in the polymerization of styrene are unambiguous evidence that the copolymerization proceeds according to the pseudoliving radical mechanism. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7COA of Formula: C14H12S2).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. COA of Formula: C14H12S2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Key volatile compounds of ‘Fuji Kiku’ apples as affected by the storage conditions and shelf life: Correlation between volatile emission by intact fruit and juice extracted from the fruit was written by Donadel, Jossie Zamperetti;Thewes, Fabio Rodrigo;Anese, Rogerio de Oliveira;Schultz, Erani Eliseu;Berghetti, Magno Roberto Pasquetti;Ludwig, Vagner;Klein, Bruna;Cichoski, Alexandre Jose;Barin, Juliano Smanioto;Both, Vanderlei;Brackmann, Auri;Wagner, Roger. And the article was included in Food Research International in 2019.Related Products of 868-57-5 This article mentions the following:

For the ‘Fuji Kiku’ apple, this study aimed: (i) to evaluate the volatile compounds (VCs) from headspace storage chambers with static controlled atm. (CA) and with dynamic controlled atm. based on chlorophyll fluorescence (DCA-CF) and based on RQ (DCA-RQ1.5) at ninth month of storage, during 1 and 7 days of shelf life of intact fruit, and in apple juice headspace and (ii) to determine the correlation of the VCs in the headspace from storage chambers and fruit during shelf life with the headspace VCs from apple juice as markers of quality. The VCs were isolated by solid phase microextraction (HS-SPME) and analyzed by gas chromatog. In the storage chambers, Et linear chain esters were detected mainly in DCA-RQ1.5, while acetaldehyde and (E)-2-hexenal were more abundant in DCA-CF. At seven days of shelf life, fermentative metabolic compounds had reduced emissions given the opening time of the chamber, while there were higher emissions of branched chain esters, especially Et 2-Me butanoate in DCA-RQ1.5. The correlation was high and pos. between the VCs present in the juice and those emitted by the intact fruit during seven days of shelf life, demonstrating that the concentration of VCs in juice can be used to estimate the emissions from whole fruit. DCA-RQ1.5 storage promoted the synthesis of VCs typical of the ‘Fuji’ apple aroma after a prolonged storage period, even under extremely low partial pressure of oxygen (average 0.15 kPa), contributing to better quality control of characteristic fruit odor and aroma. In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5Related Products of 868-57-5).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Related Products of 868-57-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of Nine-Membered Carbocycles by the [4+3+2] Cycloaddition Reaction of Ethyl Cyclopropylideneacetate and Dienynes was written by Saito, Shinichi;Maeda, Kyotaro;Yamasaki, Ryu;Kitamura, Takuya;Nakagawa, Minami;Kato, Korehito;Azumaya, Isao;Masu, Hyuma. And the article was included in Angewandte Chemie, International Edition in 2010.Safety of Diethyl 2-(prop-2-yn-1-yl)malonate This article mentions the following:

In presence of [Ni(cod)₂] and PPh₃, [4+3+2] cycloaddition reactions of Et cyclopropylideneacetate and dienynes gave nine-membered carbocyclic compounds E.g., reaction of Et cyclopropylideneacetate and (E)-2-[2-methyl-2,4-pentadienyl]-2-(2-propynyl)malonic acid di-Et ester gave 57% bicyclic compound I. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Safety of Diethyl 2-(prop-2-yn-1-yl)malonate).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Safety of Diethyl 2-(prop-2-yn-1-yl)malonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Some intermediate bio-transformants during biodegradation of high molecular weight phenanthrene and fluoranthene by cyanobacterial species – Aulosira fertilissima ghose was written by Nirmal Kumar, J. I.;Barot, Megha;Khan, Shamiyan R.. And the article was included in International Journal of Applied Sciences and Biotechnology in 2013.Quality Control of Dimethyl decanedioate This article mentions the following:

The PAHs compounds are known to be carcinogenic, teratogenic, mutagenic and toxic to all living organism. Handful of literature is available on biodegradation of these compounds by bacteria and fungi, however, scanty work is done by using microalgae on biodegradation of these two PAHs. In this investigation, the efficiency of Aulosira fertilissima Ghose to remove fluoranthene (0.001gm.ml-1), phenanthrene (0.001gm.ml-1) and a mixture of both (each at concentration of 0.0005gm.ml-1) were evaluated for intermediate bio-transformants during biodegradation by using GCMS. The result showed that the efficiency of Aulosira fertilissima for removal and biodegradation of phenanthrene was higher than fluoranthene, indicate fluoranthene was more stable and recalcitrant. PAHs uptake after 7-days of treatment was 80% and 66% of these phenanthrene and fluoranthene ,resp. by the cyanobacteria .The synergetic effect of fluoranthene on phenanthrene was observed, presence of fluoranthene stimulate the degradation of phenanthrene due to which phenanthrene produce more bio-transformants . Some intermediates were observed like Me linoleate, 4-(2,2- dimethyl-6-methylenecyclohexylidene)-3-methyl-,(Z)- etc. for phenanthrene biodegradation process while 2,3-dihydrofluoranthene, (1R,5R)-2-isopropyl-5-methylcyclohexanol, for fluoranthene degradation Moreover, 3-isopropylidene-2,2-dimethyl-6-phenyl-1,4-oxathiane, 7- phenyltridecane, diphenylacetylene, for mixture of two PAHs applied. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Quality Control of Dimethyl decanedioate).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Quality Control of Dimethyl decanedioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Comprehensive chemical characterisation of Durio zibethinus was written by Chua, L. S.;Lee, Y. C.. And the article was included in Acta Alimentaria in 2020.SDS of cas: 868-57-5 This article mentions the following:

This study investigated the chem. properties of Durio zibethinus (Durian) in Malaysia. The cultivars included in the present study were D101, D197, and Kampung. A wide range of chem. properties such as proximate nutritional content, minerals, total phenolic content was analyzed using established anal. methods. The antioxidant capacity in term of free radical scavenging activity was determined using colorimetric assay, whereas metabolite profiles of samples were analyzed by hyphenated high throughput tool like GC-MS. The results showed that D197 durian had the highest content of ash, protein, fat, and carbohydrate, but the lowest moisture level. Potassium was found to be the highest mineral (8.68-11.36 mg g^-1), followed by sodium (3.2-7.6 mg g^-1), magnesium (0.86-1.88 mg g^-1), and calcium (2.74-3.80 mg g^-1) in the tested cultivars. The major sulfur containing compounds (% relative peak area) such as hydrogen sulfide (5.0-8.3%), methanethiol (0.5-1.0%), ethanethiol (20.7-35.0%), 1-propanethiol (2.7-9.5%), and di-Et disulfide (0.6-1.9%), and esters, especially Et 2-methylbutanoate (10.0-15.0%), Me 2-methylbutanoate (1.0%), and Pr 2-methylbutanoate (1.5%) were detected when fresh samples were heated in headspace GC-MS. However, those compounds evaporated during ultrasound assisted extraction and oven drying even at 40°C. In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5SDS of cas: 868-57-5).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.SDS of cas: 868-57-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics