Category: 86549-27-1

Padwa, Albert published the artcileA Rh(II)-catalyzed cycloaddition approach toward the synthesis of komaroviquinone, Safety of Ethyl 2,2-dimethylpent-4-enoate, the main research area is komaroviquinone icetexane core synthesis cyclization cycloaddition rhodium catalyzed.

Using a rhodium(II)-catalyzed cyclization/cycloaddition sequence as the key reaction step, the icetexane core of komaroviquinone (I) was constructed by an intramol. dipolar-cycloaddition of a carbonyl ylide dipole across a tethered π-bond. The ylide was arrived at by cyclization of a rhodium carbenoid intermediate onto a proximal ester group. Efforts toward the preparation of the required precursor for elaboration to the natural product are discussed.

Tetrahedron published new progress about Cyclization. 86549-27-1 belongs to class esters-buliding-blocks, name is Ethyl 2,2-dimethylpent-4-enoate, and the molecular formula is C9H16O2, Safety of Ethyl 2,2-dimethylpent-4-enoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Padwa, Albert published the artcileEfficient Construction of the Oxatricyclo[6.3.1.00,0]dodecane Core of Komaroviquinone Using a Cyclization/Cycloaddition Cascade of a Rhodium Carbenoid Intermediate, Formula: C9H16O2, the main research area is oxatricyclododecane core komaroviquinone preparation cyclization cycloaddition cascade rhodium carbenoid.

The rhodium(II)-catalyzed cyclization/cycloaddition cascade of a o-carbomethoxyaryl diazo dione is described as a potential route to the oxatricyclo[6.3.1.00,0]dodecane substructure I (R = H, Me) of the icetexane diterpene komaroviquinone. The initially formed carbonyl ylide dipole prefers to cyclize to an epoxide at 25 °C but can be induced to undergo cycloaddition across the tethered π-bond at higher temperatures

Organic Letters published new progress about Cyclization. 86549-27-1 belongs to class esters-buliding-blocks, name is Ethyl 2,2-dimethylpent-4-enoate, and the molecular formula is C9H16O2, Formula: C9H16O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mocny, Piotr published the artcileSynthesis of Loop Poly(Methyl Methacrylate) Brushes via Chain-End Postpolymerization Modification, Application In Synthesis of 86549-27-1, the main research area is polymethyl methacrylate brush postpolymn.

Polymer brushes are typically densely grafted assemblies of polymer chains that are tethered via one end group to a solid substrate. Anchoring linear polymer chains via both end groups to a surface results in loop-type polymer brushes. Although loop polymer brushes have been shown to be able to outperform their linear, single-chain-end tethered analogs, for example, with respect to the prevention of biofouling or reducing friction, this brush architecture has received only relatively limited attention. Loop-type polymer brushes are mostly prepared following grafting-onto approaches using α,ω-heterobifunctional polymers. Grafting-from strategies, so far, have been rarely explored, but could further expand the range of accessible polymer mol. weights and brush grafting densities and allow the preparation of surface-attached polymer loops from a wider scope of monomers. This manuscript reports an alternative grafting-from strategy for the preparation of loop-type poly(Me methacrylate) (PMMA) brushes. The strategy presented here starts with the preparation of linear polymer grafts using conventional surface-initiated atom transfer radical polymerization The free chain-ends of the linear PMMA grafts are modified with an allyl group and subsequently subjected to a metathesis reaction to induce loop closure. The formation of the loop PMMA brushes was monitored by gel permeation chromatog. anal. after cleavage of the polymer from the silica nanoparticles.

Macromolecules (Washington, DC, United States) published new progress about Nanoparticles. 86549-27-1 belongs to class esters-buliding-blocks, name is Ethyl 2,2-dimethylpent-4-enoate, and the molecular formula is C9H16O2, Application In Synthesis of 86549-27-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Satake, Akiharu published the artcileNovel η3-Allylpalladium-Pyridinylpyrazole Complex: Synthesis, Reactivity, and Catalytic Activity for Cyclopropanation of Ketene Silyl Acetal with Allylic Acetates, Safety of Ethyl 2,2-dimethylpent-4-enoate, the main research area is allyl palladium pyridinyl pyrazole preparation catalyst; cyclopropanation ketene silyl acetal allylic acetate; catalysis cyclopropanation ketene silyl acetal allylic.

Novel cationic η3-allylpalladium-pyridinylpyrazole complexes I (R = Me, But) were synthesized from 3-alkyl-5-(2-pyridinyl)pyrazole and η3-allylpalladium chloride dimer in the presence of AgBF4. Cationic complexes I were converted into neutral complexes II under basic conditions. These complexes were characterized by 1H, 13C, and 15N NMR studies. Neutral complexes II have high catalytic activity for cyclopropanation of ketene silyl acetals with allylic acetates. Comparison of the cationic and neutral complexes and the reaction mechanism of cyclopropanation were discussed.

Journal of the American Chemical Society published new progress about Cyclopropanation. 86549-27-1 belongs to class esters-buliding-blocks, name is Ethyl 2,2-dimethylpent-4-enoate, and the molecular formula is C9H16O2, Safety of Ethyl 2,2-dimethylpent-4-enoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Deng, Billy published the artcileNeopentyl Esters as Robust Linkers for Introducing Functionality to Bis-MPA Dendrimers, Quality Control of 86549-27-1, the main research area is neopentyl ester linker functionality bisMPA dendrimer.

A series of neopentyl carboxylic acids bearing functionality amenable to click chem. were prepared and then appended to high-generation bis-MPA dendrons via fluoride-promoted esterification. The nucleophilic stability of neopentyl and non-neopentyl dendrons in acidic to basic phosphate buffers was compared by monitoring degradation via quant. 1H NMR. The neopentyl periphery dendrons were found to be highly resistant to hydrolysis under all exptl. conditions. The neopentyl groups also did not impede click functionalization onto the dendrons.

Macromolecules (Washington, DC, United States) published new progress about Dendrimers Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 86549-27-1 belongs to class esters-buliding-blocks, name is Ethyl 2,2-dimethylpent-4-enoate, and the molecular formula is C9H16O2, Quality Control of 86549-27-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Jeong, Yun-Kyung published the artcileIntramolecular hydroalkoxylation in Bronsted acidic ionic liquids and its application to the synthesis of (±)-centrolobine, Computed Properties of 86549-27-1, the main research area is sulfonic acid substituted triazolium imidazolium ionic liquid preparation; cyclic ether preparation; racemic centrolobine stereoselective preparation; hydroalkoxylation unsaturated alc sulfonic acid substituted ionic liquid catalyst; stereoselective cyclization unsaturated alc sulfonic acid substituted ionic liquid; Bronsted acidic ionic liquid preparation catalyst stereoselective cyclization.

Sulfonic acid-substituted triazolium and imidazolium ionic liquids such as I·CF3SO3- (X = N, CH) are prepared; I·CF3SO3- (X = N, CH) act as catalysts for the cyclization reactions of alkenyl alcs. such as HOCH2CMe2CH2CH:CH2 to give cyclic ethers such as 2,4,4-trimethyltetrahydrofuran. (±)-Centrolobine II (R = H) is prepared using the stereoselective cyclization of III to II (R = PhCH2) in the presence of I·CF3SO3- (X = N or CH) as the key step; III is prepared in three steps from p-anisaldehyde and 4-benzyloxyphenylethyl bromide. I·CF3SO3- (X = N) can be used three times for the cyclization of 2,2-diphenyl-4-penten-1-ol to 2-methyl-4,4-diphenyltetrahydrofuran.

Organic & Biomolecular Chemistry published new progress about Cyclic ethers Role: SPN (Synthetic Preparation), PREP (Preparation). 86549-27-1 belongs to class esters-buliding-blocks, name is Ethyl 2,2-dimethylpent-4-enoate, and the molecular formula is C9H16O2, Computed Properties of 86549-27-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Vadola, Paul A. published the artcileC-H Bond Functionalization via Hydride Transfer: Formation of α-Arylated Piperidines and 1,2,3,4-Tetrahydroisoquinolines via Stereoselective Intramolecular Amination of Benzylic C-H Bonds, Name: Ethyl 2,2-dimethylpent-4-enoate, the main research area is arylated piperidine tetrahydroisoquinoline benzyl stereoselective intramol amination hydride transfer.

We here report a study of the intramol. amination of sp3 C-H bonds via the hydride transfer cyclization of N-tosylimines (HT-amination). In this transformation, 5-aryl aldehydes are subjected to N-toluenesulfonamide in the presence of BF3·OEt2 to effect imine formation and HT-cyclization, leading to 2-arylpiperidines and 3-aryl-1,2,3,4-tetrahydroisoquinolines in a one-pot procedure. We examined the reactivity of a range of aldehyde substrates as a function of their conformational flexibility. Substrates of higher conformational rigidity were more reactive, giving higher yields of the desired products. However, a single substituent on the alkyl chain linking the N-tosylimine and the benzylic sp3 C-H bonds was sufficient for HT-cyclization to occur. In addition, an examination of various arenes revealed that the electronic character of the hydridic C-H bonds dramatically affects the efficiency of the reaction. We also found that this transformation is highly stereoselective; 2-substituted aldehydes yield cis-2,5-disubstituted piperidines, while 3-substituted aldehydes afford trans-2,4-disubstituted piperidines. The stereoselectivity is a consequence of thermodn. control. The pseudoallylic strain between the arene and tosyl group on the piperidine ring is proposed to rationalize the greater stability of the isomer with the aryl ring in the axial position. This preferential placement of the arene is proposed to affect the observed stereoselectivity.

Journal of Organic Chemistry published new progress about Amination, stereoselective (intramol.). 86549-27-1 belongs to class esters-buliding-blocks, name is Ethyl 2,2-dimethylpent-4-enoate, and the molecular formula is C9H16O2, Name: Ethyl 2,2-dimethylpent-4-enoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics