Category: 85-91-6

Yuan, Zaifeng; Zhu, Chunyu; Ma, Zhixian; Xia, Chengfeng published an article in 2018, the title of the article was Copper-catalyzed amination of an α-C(sp3)-H bond in inactivated ethers to synthesize α-aminonitriles.Quality Control of Methyl N-Methylanthranilate And the article contains the following content:

A copper-catalyzed functionalization of inert cyclic ethers was developed to provide α-aminonitriles via a cascade oxidation/amination/ring-opening/cyanation reaction. A series of highly versatile α-aminonitriles were obtained from primary or secondary anilines, and heterocyclic and aliphatic amines with high yields. This process features excellent functional group tolerance, a broad substrate scope, and high activity under ambient conditions. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Quality Control of Methyl N-Methylanthranilate

The Article related to aminonitrile preparation, ether amine cyanide amination copper catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Nitriles, Isonitriles, and Acyl Cyanides and other aspects.Quality Control of Methyl N-Methylanthranilate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Qiao, Chang; Yao, Xiang-Yang; Liu, Xiao-Fang; Li, Hong-Ru; He, Liang-Nian published an article in 2018, the title of the article was Efficient Iron-Catalyzed Reductive N-Alkylation of Aromatic Amines with Carboxylic Acids and Phenylsilane.Application of 85-91-6 And the article contains the following content:

Herein, an earth-abundant iron-catalyzed protocol for the N-alkylation of anilines using carboxylic acid as alkyl source and phenylsilane as reducing agent was reported. With Fe2(CO)9 as a catalyst, a broad range of primary and secondary anilines are successfully converted to the corresponding tertiary anilines. Furthermore, this N-alkylation mainly goes through the amide pathway; while the aldehyde pathway can not be ruled out. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Application of 85-91-6

The Article related to tertiary aniline preparation green chem, aniline carboxylic acid reductive alkylation iron catalyst phenylsilane, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Application of 85-91-6

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 1, 2020, Abraham, Michael H.; Abraham, Raymond J.; Aghamohammadi, Amin; Afarinkia, Kamyar; Liu, Xiangli published an article.SDS of cas: 85-91-6 The title of the article was The assessment of intramolecular hydrogen bonding in ortho-substituted anilines by an NMR method. And the article contained the following:

We describe the Δlog P method for the assessment of intramol. hydrogen bonds (IMHBs), and show that it is not a very general method of distinguishing between mols. in which there is an IMHB and mols. in which there is no IMHB. The ‘double’ Δlog P method of Shalaeva et al. is a much more reliable method for the assessment of IMHB but requires the synthesis of a model compound and the determination of no less than four water-solvent partition coefficients In addition, it is difficult to apply to compounds that contain more than one hydrogen bond acidic group capable of IMHB. We then describe our NMR method of assessing IMHB, based on 1H NMR chem. shifts in solvents DMSO and CDCl3. We have determined 1H NMR chem. shifts for a number of ortho-substituted anilines and show that the only compound we have studied that forms an IMHB is Me 2-methylaminobenzoate though there is no IMHB present in Me 2-aminobenzoate. This apparently anomalous result is supported by both MM and ab initio calculations The NMR method is much simpler and less time consuming than other methods for the assessment of IMHB. It provides a quant. assessment of IMHB and can be applied to mols. with more than one hydrogen bond acidic group. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).SDS of cas: 85-91-6

The Article related to ortho aniline nmr chem shift hydrogen bond, Physical Organic Chemistry: Resonance Spectra (Electron Spin, Nuclear Magnetic and Fourier Transform Nuclear Magnetic, Quadrupole, etc.) and other aspects.SDS of cas: 85-91-6

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Ester – an overview | ScienceDirect Topics

Li, Shangda; Wang, Hang; Weng, Yunxiang; Li, Gang published an article in 2019, the title of the article was Carboxy Group as a Remote and Selective Chelating Group for C-H Activation of Arenes.HPLC of Formula: 85-91-6 And the article contains the following content:

The first example of carboxy group assisted, remote-selective C(sp2)-H activation with a PdII catalyst was developed and proceeds through a possible κ2 coordination of the carboxy group, thus suppressing the ortho-C-H activation through κ1 coordination. Besides meta-C-H olefination, direct meta-arylation of hydrocinnamic acid derivatives with low-cost aryl iodides was achieved for the first time. These findings may motivate the exploration of novel reactivities of the carboxy assisted C-H activation reactions with intriguing selectivities. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).HPLC of Formula: 85-91-6

The Article related to carboxy group remote chelating arene activation, c−h activation, arylation, coordination modes, palladium, synthetic methods, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.HPLC of Formula: 85-91-6

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wauke, Hisashi; Matsuo, Kazumasa; Matsumoto, Kenji; Shindo, Mitsuru published an article in 2016, the title of the article was Synthesis of Dissymmetric Malonic Acid Monoamides from Symmetric Dithiomalonates.Computed Properties of 85-91-6 And the article contains the following content:

A highly selective synthesis of dissym. S,N-malonates from sym. dithiomalonates under mild conditions has been reported. This reaction was accelerated using a previously developed Cu(II) catalyst. When an aliphatic amine, such as dibenzylamine, diallylamine, diisopropylamine, etc. was used as the nucleophile, the amine also worked as a base and accelerated the amination reaction. Kinetic studies indicated that the key step of this reaction is the thermal formation of an acylketene, and its stability mainly contributes to the selectivity of the reaction. The synthetic utility of dissym. S,N-malonates is also shown by the synthesis of linomide. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Computed Properties of 85-91-6

The Article related to malonic acid monoamide preparation, dithiomalonate amine amidation copper catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Computed Properties of 85-91-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On November 15, 2020, Liu, Yongquan; Xue, Ahui; Wang, Siyu; Hao, Yingbin; Cui, Meng; Liu, Lihua; Luo, Liping published an article.HPLC of Formula: 85-91-6 The title of the article was Metabolic response of Citrus limon to Asian citrus psyllid infestation revealed by EESI-MS and HPLC. And the article contained the following:

Asian citrus psyllid (ACP) causes direct and indirect damage to the citrus industry. Extractive electrospray ionization mass spectrometry (EESI-MS) and high performance liquid chromatog. (HPLC) were used to detect the metabolites of C. limon leaves at 0, 12, 24, and 72 h after ACP treatment. The EESI-MS results showed that ACP infestation significantly affected metabolites within a short feeding duration with 8 metabolites identified. The metabolites in leaves of these four groups could be distinguished, with 55 peaks showing significant differences including Me N-methylanthranilate, caffeic acid, and syringic acid. The quantification of 15 phenolic compounds with HPLC-UV method in C. limon leaves after ACP infestation showed that the total content of them reached a peak of 3504.69μg g-1 at 12 h, with 9 phenolic compounds changing significantly (P < 0.05). A total of 21 metabolites identified in this study were involved in the biosynthesis pathways of flavonoid, flavone and flavonol, isoflavonoid and phenylpropanoid, and the degradation of aminobenzoate. Contents of epicatechin and caffeic acid increased with the feeding time of ACP as detected by both EESI-MS and HPLC. This may be related to plant defense. This study provides novel insights into the biochem. relationship of ACP and its host plants. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).HPLC of Formula: 85-91-6

The Article related to citrus metabolism hplc mass spectrometry, diaphorina citri kuwayama, extractive electrospray ionization mass spectrometry, herbivore, induced resistance, phenolic compounds and other aspects.HPLC of Formula: 85-91-6

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 30, 2019, Lee, Hye Lim; Kim, Song-Yi; Kim, Eun Ji; Han, Da Ye; Kim, Bong-Gyu; Ahn, Joong-Hoon published an article.HPLC of Formula: 85-91-6 The title of the article was Synthesis of methylated anthranilate derivatives using engineered strains of Escherichia coli. And the article contained the following:

Anthranilate derivatives have been used as flavoring and fragrant agents for a long time. Recently, these compounds are gaining attention due to new biol. functions including antinociceptive and analgesic activities. Three anthranilate derivatives, N-methylanthranilate, Me anthranilate, and Me N-methylanthranilate were synthesized using metabolically engineered stains of Escherichia coli. NMT encoding N-methyltransferase from Ruta graveolens, AMAT encoding anthraniloyl-CoA (CoA):methanol acyltransferase from Vitis labrusca, and pqsA encoding anthranilate CoA ligase from Pseudomonas aeruginosa were cloned and E. coli strains harboring these genes were used to synthesize the three desired compounds E. coli mutants (metJ, trpD, tyrR mutants), which provide more anthranilate and/or S-adenosyl methionine, were used to increase the production of the synthesized compounds MS/MS anal. was used to determine the structure of the products. Approx., 185.3μM N-methylanthranilate and 95.2μM Me N-methylanthranilate were synthesized. This is the first report about the synthesis of anthranilate derivatives in E. coli. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).HPLC of Formula: 85-91-6

The Article related to escherichia methylated anthranilate derivative engineering, anthranilate, n-methyltransferase, anthraniloyl-coenzyme a (coa):methanol acyltransferase, metabolic engineering and other aspects.HPLC of Formula: 85-91-6

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gomez-Calvario, Victor; Ramirez-Cisneros, M. Angeles; Acevedo-Quiroz, Macdiel; Rios, Maria Yolanda published an article in 2019, the title of the article was Chemical composition of Helietta parvifolia and its in vitro anticholinesterase activity.Related Products of 85-91-6 And the article contains the following content:

The chem. composition of the essential oil and the n-hexane (Hex), Et Acetate (EtOAc) and butanol (BuOH) extracts from the leaves of Helietta parvifolia were determined by detailed GC-MS anal., spectroscopic and spectrometric data. Eighty-four compounds were identified, revealing a furoquinoline alkaloid-rich composition The phytochem. anal. of the extracts allowed the isolation of eigth furoquinoline alkaloids. Retention indexes in GC-MS for six of this alkaloids are reported for the first time. Furoquinoline alkaloids are acetylcholinesterase inhibitors. Thus, the essential oil and extracts were submitted to this in vitro assay. The EtOAc and BuOH extracts showed potent activity, with IC50 of 9.7 and 12.9 μg mL-1, resp. Addnl., a correlation of their chem. constituents, established by principal component anal. (PCA) demonstrated a similar profile and a high content of alkaloids. It is for these reasons that the authors can assume that the alkaloid content in these extracts could be responsible for their anticholinesterase activity. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Related Products of 85-91-6

The Article related to helietta essential oil furoquinoline alkaloid acetylcholinesterase inhibitor, gc-ms, pca, ri, anticholinesterase activity, furoquinoline alkaloids, phytochemical analysis and other aspects.Related Products of 85-91-6

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Frutos-Pedreno, Roberto; Garcia-Lopez, Jose-Antonio published an article in 2016, the title of the article was 2-Arylacetamides as Versatile Precursors for 3-Aminoisocoumarin and Homophthalimide Derivatives: Palladium-Catalyzed Cascade Double Carbonylation Reactions.Synthetic Route of 85-91-6 And the article contains the following content:

The synthesis of biol. relevant homophthalimide and 3-aminoisocoumarin nuclei via palladium-catalyzed carbonylation of 2-(2-iodoaryl)acetamides was developed. The degree of N-substitution on the starting amide substrate dictates whether C-N or C-O coupling takes place in the final step of the catalytic cycle giving rise to each type of heterocycle. The introduction of a second C-halogen bond in the starting acetamides allows a catalytic cascade double carbonylation involving a C-H activation step to give fused heterocyclic structures. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Synthetic Route of 85-91-6

The Article related to homophthalimide aminoisocoumarin preparation palladium catalyst iodoarylacetamide carbonylation, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Synthetic Route of 85-91-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 31, 2022, Miltojevic, Ana B.; Mitic, Katarina V.; Stojanovic, Nikola M.; Randjelovic, Pavle J.; Radulovic, Niko S. published an article.Recommanded Product: Methyl N-Methylanthranilate The title of the article was Methyl and Isopropyl N-Methylanthranilates Affect Primary Macrophage Function – An Insight into the Possible Immunomodulatory Mode of Action. And the article contained the following:

To complement the knowledge on the anti-inflammatory activity of Me and iso-Pr N-methylanthranilates, two natural products with panacea-like properties, we investigated their effects on thioglycolate-elicited macrophages by evaluating macrophage ability to metabolize MTT, macrophage membrane function, and macrophage myeloperoxidase and phagocytic activities. Moreover, two addnl. aspects of the inflammatory response of these compounds, their inhibitory activity on xanthine oxidase and catalase, were studied. It was found that these two compounds regulate elicited macrophage functions, most probably by interfering with the function of cell membranes and changing the reducing cellular capacity or enzyme activity of macrophages. Nonetheless, no significant inhibitory action either towards xanthine oxidase or catalase was found, suggesting that the inhibition of these enzymes is not involved in the anti-inflammatory mode of action of these two esters. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Recommanded Product: Methyl N-Methylanthranilate

The Article related to methyl isopropyl n methylanthranilate macrophage, n-methylanthranilic acid esters, anti-inflammatory activity, immunomodulatory potential, macrophage function, oxidoreductases and other aspects.Recommanded Product: Methyl N-Methylanthranilate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics