Category: 707-07-3

On December 18, 2020, Mong, Kwok-Kong Tony; Cheng, Kuang-Chun; Lu, I-Chen; Pan, Chia-Wei; Wang, Yi-Fang; Shen, Li-Ching published an article.Application In Synthesis of (Trimethoxymethyl)benzene The title of the article was Cascade In Situ Phosphorylation and One-Pot Glycosylation for Rapid Synthesis of Heptose-Containing Oligosaccharides. And the article contained the following:

We report a one-pot glycosylation strategy for achieving rapid syntheses of heptose (Hep)-containing oligosaccharides. The reported procedure was designed to incorporate an in situ phosphorylation step into an orthogonal one-pot glycosylation. Hep-containing oligosaccharides were assembled directly from building blocks with minimal effort expended on manipulation of protecting and aglycon leaving groups. The utility of our one-pot procedure was illustrated by synthesizing partial core oligosaccharide structure present in the lipopolysaccharide of Ralstonia solanacearum. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Application In Synthesis of (Trimethoxymethyl)benzene

The Article related to oligosaccharide containing phosphorylation heptose protecting group lipopolysaccharide ralstonia solanacearum, Carbohydrates: Oligosaccharides and other aspects.Application In Synthesis of (Trimethoxymethyl)benzene

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On July 1, 2013, Picard, Sebastien; Crich, David published an article.Product Details of 707-07-3 The title of the article was Improved methods for the stereoselective synthesis of mannoheptosyl donors and their glycosides: toward the synthesis of the trisaccharide repeating unit of the Campylobacter jejuni RM1221 capsular polysaccharide. And the article contained the following:

In view of the importance of 6-deoxymannoheptosides as structural units in the Campylobacter jejuni RM1221 capsular polysaccharide, the development of effective synthetic protocols for 4-O-6-S-α-cyanobenzylidene thio-d-mannoheptapyranoside donors carrying either 3-O-naphthylmethyl or 3-O-acetyl groups is described starting from d-mannose. In particular, tris(phenylthio)methyllithium is found to undergo highly stereoselective addition to a mannose-6-aldehyde in sharp contrast to the vinyl Grignard reagent whose reactions were essentially devoid of selectivity. A brief survey of coupling reactions with the two donors indicted the 3-O-acetyl system to be highly α-selective whereas the 3-O-naphthylmethyl congener was highly β-selective indicating that the presence of the seventh carbon atom in these donors is not detrimental to coupling selectivity in either instance. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Product Details of 707-07-3

The Article related to mannoheptosyl glycoside donor stereoselective synthesis campylobacter jejuni capsular polysaccharide, Carbohydrates: Oligosaccharides and other aspects.Product Details of 707-07-3

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Ester – Wikipedia,
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On March 25, 2020, Xiao, Xiong; Zeng, Jing; Fang, Jing; Sun, Jiuchang; Li, Ting; Song, Zejin; Cai, Lei; Wan, Qian published an article.Safety of (Trimethoxymethyl)benzene The title of the article was One-Pot Relay Glycosylation. And the article contained the following:

A novel one-pot relay glycosylation has been established. The protocol is characterized by the construction of two glycosidic bonds with only one equivalent of triflic anhydride. This method capitalizes on the in situ generated cyclic-thiosulfonium ion as the relay activator, which directly activates the newly formed thioglycoside in one pot. A wide range of substrates are well-accommodated to furnish both linear and branched oligosaccharides. The synthetic utility and advantage of this method have been demonstrated by rapid access to naturally occurring phenylethanoid glycoside kankanoside F and resin glycoside merremoside D. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Safety of (Trimethoxymethyl)benzene

The Article related to triflic anhydride glycosylation glycoside merremoside oligosaccharide thioglycoside, Carbohydrates: Oligosaccharides and other aspects.Safety of (Trimethoxymethyl)benzene

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sarkar, Vikramjit; Mukhopadhyay, Balaram published an article in 2016, the title of the article was Synthesis of the Pentasaccharide Repeating Unit Related to the Exopolysaccharide from Lactobacillus plantarum C88 in the Form of its 2-Aminoethyl Glycoside.Electric Literature of 707-07-3 And the article contains the following content:

Chem. synthesis of the pentasaccharide, β-D-Galp-(1â†?)-α-D-Galp-3-O-(β-D-Glcp)-(1â†?)-α-D-Glcp-(1â†?)-β-D-Glcp, is reported by following a convenient [2+2+1] strategy. Two disaccharides α-D-Galp-(1â†?)-β-D-Glcp and α-D-Galp-(1â†?)-β-D-Galp were synthesized from com. available monosaccharides through rational protecting group manipulations and coupled to make a tetrasaccharide. The last Glc unit was coupled with the tetrasaccharide to furnish the target pentasaccharide. Stereoselective glycosylation was achieved by the activation of thioglycosides using N-iodosuccinimide and H2SO4-silica or activation of trichloroacetimidate using H2SO4-silica alone. Finally, global deprotection furnished the target mol. The target pentasaccharide has been synthesized in the form of its 2-aminoethyl glycoside to facilitate further glycoconjugate formation using the terminal free amine. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Electric Literature of 707-07-3

The Article related to aminoethyl glycoside glycoconjugate stereoselective glycosylation, oligosaccharide preparation repeating unit exopolysaccharide lactobacillus plantarum protecting group, Carbohydrates: Oligosaccharides and other aspects.Electric Literature of 707-07-3

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On November 9, 2017, Huang, Zhenhua; Li, Heran; Zhang, Qian; Lu, Fangzheng; Hong, Mei; Zhang, Zhigang; Guo, Xiaocui; Zhu, Yuanju; Li, Sanming; Liu, Hongzhuo published an article.Product Details of 707-07-3 The title of the article was Discovery of Indolinone-Based Multikinase Inhibitors as Potential Therapeutics for Idiopathic Pulmonary Fibrosis. And the article contained the following:

Idiopathic pulmonary fibrosis (IPF) is a serious and deadly disease for which treatment options are limited. The recent approval of antifibrosis agent nintedanib represents one of the first therapeutic approaches for the treatment of IPF. Here, the authors report novel indolinone-based multikinase inhibitors that target angiogenesis and fibrosis pathways and may serve as potential therapeutics for IPF. KBP-7018 is a novel, tyrosine kinase-selective inhibitor with potent effects on three fibrotic kinases (c-KIT, PDGFR, and RET). The pharmacokinetics (PK) properties of KBP-7018 were favorable in mice, rats, and dogs. In a bleomycin (BLM)-induced mouse pulmonary fibrosis model, 10, 30, and 100 mg/kg daily doses (q.d.) of KBP-7018 improved the 28-day survival rate in a dose-dependent manner. The improved efficacy of KBP-7018 compared to nintedanib provided a certain level of chem. validation for the involvement of PDGFR, c-KIT, and RET in IPF. Thus, KBP-7018 represents a novel multikinase inhibitor with differentiated activity, highly enhanced selectivity, and acceptable PK profiles that will enter phase I clin. trials. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Product Details of 707-07-3

The Article related to indolinone preparation multikinase inhibitor antifibrotic idiopathic lung fibrosis, Pharmacology: Structure-Activity and other aspects.Product Details of 707-07-3

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yu, Hui; Ma, Wenping; Liu, Yanping; Li, Jianxin; Liu, Junmin published an article in 2015, the title of the article was Analysis of volatile components in peony essence oil by headspace gas chromatography-mass spectrometry.Application of 707-07-3 And the article contains the following content:

The volatile components of 6 essential oils from peony flowers extracted by 4 different methods, namely supercritical CO2 extraction, subcritical fluid extraction, steam distillation extraction and organic solvent extraction (with three different solvents, resp.), were analyzed by headspace gas chromatog.-mass spectrometry (HS-GCMS) with a TG-5MS capillary column. A total of 32 volatile components were detected, including arenes, aleohols, esters, alkanes, ethers, ketones and aldehydes. The composition and relative contents of volatile components were significantly different among six peony essential oils. 1,3,5-Trimethoxybenzene, γ-nonanolactone and cetane were common to these 6 samples. 1,3,5-Trimethoxybenzene was the most abundant volatile component for all these oils. The peony essential oil extracted by supercritical CO2 extraction emitted a heavy flowery scent and showed the highest yield among the four extraction methods suggesting supercritical CO2 extraction is suitable for industrial production of peony essential oil. Although steam distillation extraction provided the lowest yield of peony essential oil, the oil extracted by this method contained the most abundant natural flavor components and thus it is suitable for the production of peony flower water. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Application of 707-07-3

The Article related to volatile component peony essence oil, Food and Feed Chemistry: Analysis and other aspects.Application of 707-07-3

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Porcu, Stefania; Luridiana, Alberto; Martis, Alberto; Frongia, Angelo; Sarais, Giorgia; Aitken, David J.; Boddaert, Thomas; Guillot, Regis; Secci, Francesco published an article in 2018, the title of the article was Acid-catalyzed synthesis of functionalized arylthio cyclopropane carbaldehydes and ketones.Related Products of 707-07-3 And the article contains the following content:

A general strategy for the synthesis of arylthio cyclopropyl carbaldehydes I (R = H, 4-Me, 3-Me, etc.) and ketones II (R = Et, Ph, n-Pr; R1 = H, Me, OBn) via a Bronsted acid catalyzed arylthiol addition/ring contraction reaction sequence has been exploited. The procedure led to a wide panel of cyclopropyl carbaldehydes in generally high yields and with broad substrate scope. Mechanistic aspects and synthetic applications of this procedure were investigated. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Related Products of 707-07-3

The Article related to arylthio cyclopropyl carbaldehyde ketone preparation bronsted acid catalyst, arylthiol hydroxycyclobutanone ring contraction reaction, Alicyclic Compounds: Cyclopropanes and other aspects.Related Products of 707-07-3

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Ester – an overview | ScienceDirect Topics

On May 15, 2020, Garcia, Anthony D.; Leech, Matthew C.; Petti, Alessia; Denis, Camille; Goodall, Iain C. A.; Dobbs, Adrian P.; Lam, Kevin published an article.Name: (Trimethoxymethyl)benzene The title of the article was Anodic Oxidation of Dithiane Carboxylic Acids: A Rapid and Mild Way to Access Functionalized Orthoesters. And the article contained the following:

A new electrochem. methodol. has been developed for the preparation of a wide variety of functionalized orthoesters under mild and green conditions from easily accessible dithiane derivatives The new methodol. also offers an unprecedented way to access tri(fluorinated) orthoesters, a class of compound that has never been studied before. This provides the community with a rapid and general method to prepare libraries of functionalized orthoesters from simple and readily available starting materials. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Name: (Trimethoxymethyl)benzene

The Article related to dithianecarboxylic acid alc electrochem oxidation orthoesterification green chem, ortho ester preparation, Aliphatic Compounds: Ethers and Sulfides and other aspects.Name: (Trimethoxymethyl)benzene

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 19, 2022, Peterson, Joshua W.; Burt, Scott R.; Yuan, Yu; Harper, James K. published an article.Quality Control of (Trimethoxymethyl)benzene The title of the article was Rapid, quantitative nuclear magnetic resonance test for oxygen-17 enrichment in water. And the article contained the following:

NMR (NMR) studies involving 17O are increasingly important in mol. biol., material science, and other disciplines. A large number of these studies employ H217O as a source of 17O, and this reliance can be limiting because the high cost of H217O. To overcome this constraint, a recent study proposed a distillation scheme capable of producing significant quantities of H217O at a low cost. Although this method is reported to be effective, the reactions proposed to quantify percent of 17O enrichment are either time intensive or have a risk of errors due to the isotope effect. Here, an alternative reaction scheme is described to measure 17O water that ultimately creates Me benzoate as the sole 17O-containing product. The proposed reaction is completed in a matter of minutes at room temperature, produces only one 17O product, and requires no clean-up step. The large isotope shift observed in solution NMR between the 13C=16O and 13C=17O resonances allows for integration of the individual peaks. This 13C NMR anal. is found to be highly accurate over a wide enrichment range and is accessible to most NMR spectroscopists. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Quality Control of (Trimethoxymethyl)benzene

The Article related to rapid quant nmr test oxygen enrichment water, Placeholder for records without volume info and other aspects.Quality Control of (Trimethoxymethyl)benzene

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Ester – an overview | ScienceDirect Topics

Wang, Zhenzhen; Jork, Nikolaus; Bittner, Tamara; Wang, Huanchen; Jessen, Henning J.; Shears, Stephen B. published an article in 2020, the title of the article was Rapid stimulation of cellular Pi uptake by the inositol pyrophosphate InsP8 induced by its photothermal release from lipid nanocarriers using a near infra-red light-emitting diode.Synthetic Route of 707-07-3 And the article contains the following content:

Inositol pyrophosphates (PP-InsPs), including diphospho-myo-inositol pentakisphosphate (5-InsP7) and bis-diphospho-myo-inositol tetrakisphosphate (1,5-InsP8), are highly polar, membrane-impermeant signaling mols. that control many homeostatic responses to metabolic and bioenergetic imbalance. To delineate their mol. activities, there is an increasing need for a toolbox of methodologies for real-time modulation of PP-InsP levels inside large populations of cultured cells. Here, we describe procedures to package PP-InsPs into thermosensitive phospholipid nanocapsules that are impregnated with a near infra-red photothermal dye; these liposomes are readily accumulated into cultured cells. The PP-InsPs remain trapped inside the liposomes until the cultures are illuminated with a near infra-red light-emitting diode (LED) which permeabilizes the liposomes to promote PP-InsP release. Addnl., so as to optimize these procedures, a novel stably fluorescent 5-InsP7 analog (i.e., 5-FAM-InsP7) was synthesized with the assistance of click-chem.; the delivery and deposition of the analog inside cells was monitored by flow cytometry and by confocal microscopy. We describe quant.-controlled PP-InsP release inside cells within 5 min of LED irradiation, without measurable effect upon cell integrity, using a collimated 22 mm beam that can irradiate up to 106 cultured cells. Finally, to interrogate the biol. value of these procedures, we delivered 1,5-InsP8 into HCT116 cells and showed it to dose-dependently stimulate the rate of [33P]-Pi uptake; these observations reveal a rheostatic range of concentrations over which 1,5-InsP8 is biol. functional in Pi homeostasis. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Synthetic Route of 707-07-3

The Article related to inositol pyrophosphate cellular pi uptake photothermal release, Placeholder for records without volume info and other aspects.Synthetic Route of 707-07-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics