Category: 609-14-3

《Total synthesis of (S)-(+)-ent-phomapyrones B and surugapyrone B》 was written by Ohmukai, Hiroaki; Sugiyama, Yasumasa; Hirota, Akira; Kirihata, Mitsunori; Tanimori, Shinji. Application In Synthesis of Ethyl 2-methyl-3-oxobutanoate And the article was included in Journal of Heterocyclic Chemistry in 2020. The article conveys some information:

Phomapyrone B, the 2-pyrone isolated from the phytopathogenic fungus Leptosphaeria maculans, has been synthesized as the enantiomeric form (I) starting from (S)-2-methylbutanol. Surugapyrone B (II) isolated from Streptmyces sp. USF-6280 as an antioxidant has also been synthesized as the natural form. The absolute configuration of natural phomapyrone B was estimated to be the (R)-form and that of surugapyrone B (II) being the (S)-form. A series of 2-pyrone derivatives have been synthesized through the established procedure and their DPPH radical-scavenging activities have also been evaluated. After reading the article, we found that the author used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Application In Synthesis of Ethyl 2-methyl-3-oxobutanoate)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Application In Synthesis of Ethyl 2-methyl-3-oxobutanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Qi; Li, Yao; Zhang, Long; Luo, Sanzhong published their research in Angewandte Chemie, International Edition in 2021. The article was titled 《Catalytic Asymmetric Disulfuration by a Chiral Bulky Three-Component Lewis Acid-Base》.Application of 609-14-3 The article contains the following contents:

A three-component Lewis acid-base (Lewis trio) involving a bulky chiral primary amine, B(C6F5)3 and a bulky tertiary amine has been developed as an effective enamine catalyst for enantioselective disulfuration reactions. The bulky tertiary amine was found to activate a bulky primary-tertiary diamine-borane Lewis pair for enamine catalysis via frustrated interaction. The resulted chiral bulky Lewis trio (BLT) allows for the construction of chiral disulfides via direct disulfuration with β-ketocarbonyls or α-branched aldehydes in a practical and highly stereocontrolled manner. After reading the article, we found that the author used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Application of 609-14-3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Application of 609-14-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2022,Wang, Fei; Nishimoto, Yoshihiro; Yasuda, Makoto published an article in Angewandte Chemie, International Edition. The title of the article was 《Lewis Acid-Catalyzed Diastereoselective C-C Bond Insertion of Diazo Esters into Secondary Benzylic Halides for the Synthesis of α,β-Diaryl-β-haloesters》.Related Products of 609-14-3 The author mentioned the following in the article:

A formal carbon-carbon (C-C) bond insertion via the reaction of secondary benzylic halides (fluorides, chlorides, and bromides) with α-diazo esters catalyzed by Lewis acid catalysts was reported. Secondary benzylic halides underwent elongation to afford α,β-diaryl-β-haloesters diastereoselectively. D. functional theory calculation revealed that the present formal C-C bond insertion was the result of Lewis acid-promoted cleavage and the re-formation of a carbon-halogen bond and that the aryl-migration step determined the diastereoselectivity. Various diarylmethyl halides and α-diazo esters were applicable to this reaction system. In addition, ring expansion in cyclic benzylic chlorides was accomplished. In addition to this study using Ethyl 2-methyl-3-oxobutanoate, there are many other studies that have used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Related Products of 609-14-3) was used in this study.

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Related Products of 609-14-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recommanded Product: 609-14-3In 2021 ,《Sulfonium Salts Enable the Direct Sulfenylation of Activated C(sp3)-H Bonds》 was published in European Journal of Organic Chemistry. The article was written by Zhang, Liang; Nagaraju, Sakkani; Paplal, Banoth; Lin, Yunliang; Liu, Shuhua. The article contains the following contents:

Herein, the direct α-sulfenylation of a series of β-dicarbonyl, β-ketophosphonate, and β-ketonitrile compounds, mediated by sulfonium salts has been described. Traditionally, sulfonium salts which are synthesized by activation of dialkylsulfoxides serve as oxidizing agents or precursors of sulfur ylide. In this transformation, sulfonium salts as readily prepared and operationally simple sulfenylation reagents firstly achieved alkylsulfenylation of various activated C(sp3)-H bonds with the formation of tetra-substituted carbon center. Thus, e.g., sulfenylation of Me 2-oxocyclopentanecarboxylate with DMSO in presence of AcCl as activator and NaSbF6 in MeCN afforded I (79%). The experimental part of the paper was very detailed, including the reaction process of Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Recommanded Product: 609-14-3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Recommanded Product: 609-14-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Ming; Wu, Zheng-Jian; Song, Jinshuai; Xu, Hai-Chao published an article in 2022. The article was titled 《Electrocatalytic Allylic C-H Alkylation Enabled by a Dual-Function Cobalt Catalyst》, and you may find the article in Angewandte Chemie, International Edition.Application In Synthesis of Ethyl 2-methyl-3-oxobutanoate The information in the text is summarized as follows:

An electrocatalytic allylic C-H alkylation reaction with carbon nucleophiles RCH(R1)(C(O)R2) (R = H, F, Me, Bn, etc. ; R1 = H, CN, Me, Et; R2 = Me, OEt, pyrrolidin-1-yl, etc.) employing an easily available cobalt-salen complex as the mol. catalyst was reported. These C(3)-H/C(sp3)-H cross-coupling reactions proceed through H2 evolution and require no external chem. oxidants. Importantly, the mild conditions and unique electrocatalytic radical process ensure excellent functional group tolerance and substrate compatibility with both linear and branched terminal alkenes e.g., (hex-5-en-1-yloxy)benzene. The synthetic utility of the electrochem. method is highlighted by its scalability (up to 200 mmol scale) under low loading of electrolyte (down to 0.05 equiv) and its successful application in the late-stage functionalization of complex structures. In the part of experimental materials, we found many familiar compounds, such as Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Application In Synthesis of Ethyl 2-methyl-3-oxobutanoate)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Application In Synthesis of Ethyl 2-methyl-3-oxobutanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Liu, Xigong; Zhao, Changyin; Zhu, Rongxiu; Liu, Lei published their research in Angewandte Chemie, International Edition in 2021. The article was titled 《Construction of Vicinal Quaternary Carbon Stereocenters Through Diastereo- and Enantioselective Oxidative 1,6-Conjugate Addition》.Reference of Ethyl 2-methyl-3-oxobutanoate The article contains the following contents:

The asym. construction of vicinal quaternary carbon stereocenters with at least one moiety in acyclic systems is a formidable challenge. A solution involving diastereo- and enantioselective oxidative 1,6-conjugate addn was disclosed. The practical asym. cross-dehydrogenative coupling of 2,2-diarylacetonitriles and diverse α-substituted cyclic 1,3-dicarbonyls proceeds, for vicinal quaternary carbon stereocenters with one center in acyclic systems, in excellent yields and stereoselectivities. The generality of the approach was further demonstrated by the stereoselective creation of vicinal quaternary carbon stereocenters with both centers in acyclic systems using acyclic β-ketoesters as coupling partners. Computational studies elucidate the origins of both diastereo- and enantioselectivity. The experimental part of the paper was very detailed, including the reaction process of Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Reference of Ethyl 2-methyl-3-oxobutanoate)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Reference of Ethyl 2-methyl-3-oxobutanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2022,Jia, Zongbin; Zhang, Long; Luo, Sanzhong published an article in Journal of the American Chemical Society. The title of the article was 《Asymmetric C-H Dehydrogenative Allylic Alkylation by Ternary Photoredox-Cobalt-Chiral Primary Amine Catalysis under Visible Light》.Recommanded Product: 609-14-3 The author mentioned the following in the article:

Herein, an asym. C-H dehydrogenative allylic alkylation by a synergistic catalytic system involving a chiral primary amine, a photoredox catalyst and a cobaloxime cocatalyst was reported. The ternary catalytic system enabled the coupling of β-ketocarbonyls and olefins to afford oxo(allyl)carboxylates with good yields and high enantioselectivities. Mechanism studies disclosed a cooperative radical addition process with a chiral α-imino radical and Co(II)-metalloradical wherein the chiral primary aminocatalyst and the cobaloxime catalyst work in concert to control the stereoinduction. The experimental part of the paper was very detailed, including the reaction process of Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Recommanded Product: 609-14-3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Recommanded Product: 609-14-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《π-Coordinating Chiral Primary Amine/Palladium Synergistic Catalysis for Asymmetric Allylic Alkylation》 was written by Wang, Yaning; Chai, Junli; You, Chang; Zhang, Jie; Mi, Xueling; Zhang, Long; Luo, Sanzhong. Synthetic Route of C7H12O3 And the article was included in Journal of the American Chemical Society in 2020. The article conveys some information:

We report an arene-containing chiral primary amine as a dual aminocatalyst and ligand: the π-coordinating aminocatalyst/palladium synergistic catalysis for asym. allylic alkylation of α-branched β-ketocarbonyls. The use of arene-containing chiral primary amine catalyst led to not only enhanced reaction rate but also reversed chiral induction compared with its sterically bulky derivative Both enantiomers of the allylic adducts bearing acyclic all-carbon quaternary stereocenters could be obtained from the same configured chiral aminocatalysts with high efficiency and excellent regio-, stereo-, and enantioselectivity. Mechanistic studies revealed a distinctive Pd-arene π-coordination mode for effective catalysis. The π-coordinating chiral primary amine catalyst could be successfully applied in the asym. allylation reactions of vinylethylene carbonates, vinyl epoxides, or simple allylic alcs. In the experimental materials used by the author, we found Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Synthetic Route of C7H12O3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Synthetic Route of C7H12O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Synthesis, characterization, and determination of photophysicochemical properties of peripheral and nonperipheral tetra-7-oxy-3,4-dimethylcoumarin substituted zinc, indium phthalocyanines》 was written by Artuc, Gamze Oezguel; Karapinar, Beguemhan; Oezdemir, Muecahit; Bulut, Mustafa. Computed Properties of C7H12O3This research focused onzinc indium tetraoxydimethylcoumarinylphthalocyanine complex preparation fluorescence lifetime photodynamic therapy. The article conveys some information:

The photochem. and photophys. properties of peripheral and nonperipheral zinc and indium phthalocyanines containing 7-oxy-3,4-dimethylcoumarin synthesized were investigated in this study. 7-Hydroxy-3,4-dimethylcoumarin (1) was synthesized via Pechmann condensation reaction and then the phthalonitrile derivatives [4-(7-oxy-3,4-dimethylcoumarino)phthalonitrile (2) and 3-(7-oxy-3,4-dimethylcoumarino)phthalonitrile (3)] were synthesized by nucleophilic aromatic substitution. Phthalocyanine compounds containing coumarin units on peripheral (4 and 5) and nonperipheral (6 and 7) positions were prepared via cyclotetramerization of phthalonitrile compounds All compounds’ characterizations were performed by spectroscopic methods and elemental anal. The phthalocyanine derivatives (4-7) photochem. and photophys. properties were studied in DMF. The photophys. (fluorescence quantum yields and lifetimes) and photochem. (singlet oxygen and photodegradation quantum yields) properties of these novel phthalocyanines (4-7) were studied in DMF. They produced good singlet oxygen (e.g., ΦΔ = 0.93 for 7) and showed appropriate photodegradation (in the order of 10-5), which is very important for photodynamic therapy applications. The experimental process involved the reaction of Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Computed Properties of C7H12O3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Computed Properties of C7H12O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Synthesis and Functionalization of 5-Alkyl-6-methyl-2-thiouracils》 was published in Russian Journal of General Chemistry in 2020. These research results belong to Babushkina, A. A.; Egorov, D. M.; Kaskevich, K. I.. Formula: C7H12O3 The article mentions the following:

Number of 5-alkyl-6-methyl-2-thiouracils were obtained, the further introduction of which into the reaction with dialkyl chloroethynylphosphonates afforded a series of new dialkyl (6-alkyl-5-oxo-7-methyl-5H-thiazolo[3,2-a]pyrimidin- 3-yl)phosphonates. In addition to this study using Ethyl 2-methyl-3-oxobutanoate, there are many other studies that have used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Formula: C7H12O3) was used in this study.

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Formula: C7H12O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics