Category: 6038-19-3

Mertens, Chiel; Soete, Matthieu; Sleczkowski, Marcin L.; Palmans, Anja R. A.; Meijer, E. W.; Badi, Nezha; Du Prez, Filip E. published an article in 2020, the title of the article was Stereocontrolled, multi-functional sequence-defined oligomers through automated synthesis.Category: esters-buliding-blocks And the article contains the following content:

In contrast to biomacromols., synthetic polymers generally lack a defined monomer sequence, therefore one of the challenges of polymer chemists these days is gaining more control over the primary structure of synthetic polymers and oligomers. In this work, stereocontrolled sequence-defined oligomers were synthesized using a thiolactone-based platform. Step-wise elongation of the oligomer occurs via ring-opening of the thiolactone, resulting in the formation of stereocenters along the backbone. These initial studies indicate remarkable differences in the strength of non-covalent interactions in isotactic and atactic oligomers. Different side-chain moieties were introduced using alkyl halide building blocks and the synthetic protocol was successfully optimized and automated. Furthermore, the possible post-synthesis modification of the oligomers was demonstrated using ‘click’ chem. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Category: esters-buliding-blocks

The Article related to stereocontrolled multifunctional sequence automated oligomer, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mommer, Stefan; Truong, Khai-Nghi; Keul, Helmut; Moeller, Martin published an article in 2016, the title of the article was An epoxy thiolactone on stage: four component reactions, synthesis of poly(thioether urethane)s and the respective hydrogels.Category: esters-buliding-blocks And the article contains the following content:

The synthesis of an epoxy thiolactone is described. The reactivity of this epoxy thiolactone towards amines is evaluated and presented in a four component reaction. Upon ring opening of the thiolactone with an amine an AB-type epoxy thiol monomer is generated which in situ starts a thiol-epoxy polymerization The polymerization mechanism and kinetics are investigated: the influence of different parameters such as solvent, substrate concentration, and catalyst on the reaction course is explored. Finally, concepts for the formation of reactive hydrogels are presented. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Category: esters-buliding-blocks

The Article related to epoxy thiol lactone monomer polythioetherurethane synthesis, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On May 18, 2021, Soete, Matthieu; Mertens, Chiel; Aksakal, Resat; Badi, Nezha; Du Prez, Filip published an article.Recommanded Product: 3-Aminodihydrothiophen-2(3H)-one hydrochloride The title of the article was Sequence-Encoded Macromolecules with Increased Data Storage Capacity through a Thiol-Epoxy Reaction. And the article contained the following:

Sequence-encoded oligo(thioether urethane)s with two different coding monomers per backbone unit were prepared via a solid phase, two-step iterative protocol based on thiolactone chem. The first step of the synthetic cycle consists of the thiolactone ring opening with a primary amine, whereby the in situ released thiol is immediately reacted with an epoxide. In the second step, the thiolactone group is reinstalled to initiate the next cycle. This strategy allows to introduce two different coding monomers per synthetic cycle, rendering the resulting macromols. especially attractive in the area of (macro)mol. data storage because of their increased data storage capacity. Subsequently, the efficiency of the herein reported synthesis route and the applicability of the dual-encoded sequence-defined macromols. as a potential data storage platform were demonstrated by unraveling the exact monomer order using tandem mass spectrometry techniques. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Recommanded Product: 3-Aminodihydrothiophen-2(3H)-one hydrochloride

The Article related to sequence encoded macromol data storage thiol epoxy reaction, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Recommanded Product: 3-Aminodihydrothiophen-2(3H)-one hydrochloride

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Rong-Rong; Yan, Jun-Jie; Yang, Run-Lin; Pan, Dong-Hui; Li, Wen; Xu, Yu-Ping; Wang, Li-Zhen; Wang, Xin-Yu; Yang, Min published an article in 2017, the title of the article was One-pot synthesis of soluble and fluorescent aliphatic hyperbranched poly(amide-imide) with solvent-dependent emission.Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride And the article contains the following content:

Aliphatic hyperbranched poly(amide-imide) was facilely prepared by employing a functional thiolactone-maleimide monomer. Highly efficient, selective and quant. properties of amine-maleimide Michael addition and aminolysis of a thiolactone guaranteed the generation of an ABB’ thiol-yne intermediate without side products, followed by consecutive thiol-yne click reaction in one-pot. The hyperbranched structure of the poly(amide-imide) was confirmed by NMR spectroscopy and triple-detector GPC/SEC anal. Addnl., due to the presence of aminosuccinimide fluorophores and intrinsic phys. property of hyperbranched polymers, this aliphatic hyperbranched poly(amide-imide) possessed solvent-dependent emission and presented good solubility in various organic solvents. © 2017 Wiley Periodicals, Inc. A J. Polym. Sci., Part A: Polym. Chem. 2017. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

The Article related to aliphatic hyperbranched polyamideimide solvent emission, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 30, 2018, Yu, Lei; Zhang, Ze; You, Ye-Zi; Hong, Chun-Yan published an article.Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride The title of the article was Synthesis of sequence-controlled polymers via sequential thiol-ene and amino-yne click reactions in one pot. And the article contained the following:

Sequence-controlled polymers are prepared by the combination of thiol-ene click reaction and amino-yne click reaction. Due to the high selectivity of the amine unit and thiol unit toward thiolactone, methacrylate, propiolate, etc., the sequence of the resulting polymers can be easily controlled by monomer-addition sequence. Moreover, thiol-ene click reaction and amino-yne click reaction can be carried out under mild conditions without need of any catalyst. Different kinds of sequence-controlled copolymers have been prepared by the combination of thiol-ene click reaction and amino-yne click reaction in one pot. NMR spectra and GPC traces confirmed the formation of polymers with high mol. weight and controlled sequence structure. Therefore, we provide a new method for the preparation of functional polymers with well-controlled sequences. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

The Article related to synthesis sequential thiol ene amino yne click polymer, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 15, 2022, Yan, Junjie; Wang, Xinyu; Xiong, Jianjun; Wang, Lizhen; Pan, Donghui; Xu, Yuping; Yang, Min published an article.Application of 6038-19-3 The title of the article was Uncovering divergent fluorescence of aliphatic polyamides: Synthesis, dual polymerization-induced emissions, and organelle-specific imaging. And the article contained the following:

Amides, essential structural units to construct aliphatic polyamides, peptides and proteins, have been lately demonstrated with non-traditional intrinsic luminescence (NTIL). However, diversified compositions, structures and environments in current research render aliphatic polyamides with significant divergences in NTILs and obfuscate the fluorescent nature. Herein, we construct a library of aliphatic polyamides by thiolactone chem. This versatile approach equips the resultant polyamides with tunable amide category, amide distribution, and chem. environment, facilitating to uncover the structure-NTILs relationship of aliphatic fluorescent polyamides. Unexpectedly, aliphatic polyamides possess dual polymerization-induced emissions (PIEs) due to different self or non-self hydrogen bonding interactions, which result in distinct fluorescence quenching effect upon various metal ions. Addnl., in-situ generated sulfhydryl can simplify the hetero-atom doping strategy and regulate the PIEs of aliphatic polyamides by modulating the intermol. forces among the system or with the environment. Furthermore, the introduction of a piperazine unit provides the resultant fluorescent polyamide with lysosome-specific anchoring, which lights up the organelle. These findings not only elucidate the origin of divergent fluorescence in aliphatic polyamides, but also afford fundamental basis to develop new kinds of aliphatic polymers with controllable fluorescence and functionality. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Application of 6038-19-3

The Article related to aliphatic polyamide polymerization induced emission thiolactone chem fluorescence, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Application of 6038-19-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Ze; Tan, Zi-Bin; Hong, Chun-Yan; Wu, De-Cheng; You, Ye-Zi published an article in 2016, the title of the article was One-pot sequential multicomponent reaction and a multicomponent polymerization method for the synthesis of topologically different polymers.Application In Synthesis of 3-Aminodihydrothiophen-2(3H)-one hydrochloride And the article contains the following content:

Reactions combining two or more multicomponent reactions performed sequentially in a single pot have attracted great interest due to the fact that they enable more step- and time economic conversions of simple starting materials into complex targets. However, so far, no such reaction has been applied in the synthesis of topol. different polymers. Here, we first report a novel strategy combining the sequential multicomponent reaction (MCR) of a primary amine, a thiolactone and an alkene and the multicomponent polymerization (MCP) of an azide, an alkyne and a secondary amine in one-pot for the syntheses of topol. different polymers (linear, hyperbranched, core-shell polymers). This strategy provides an effective method that can control the sequence and topol. of the obtained polymers simultaneously. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Application In Synthesis of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

The Article related to amine thiolactone alkene multicomponent reaction azide multicomponent polymerization topol, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Application In Synthesis of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 31, 2018, Paenkaew, Sujittra; Rutnakornpituk, Metha published an article.SDS of cas: 6038-19-3 The title of the article was Effect of alkyl chain lengths on the assemblies of magnetic nanoparticles coated with multi-functional thiolactone-containing copolymer. And the article contained the following:

This work presents the synthesis of magnetite nanoparticle (MNP) coated with poly(N,N-diethylaminoethyl methacrylate)-b-poly(N-iso-Pr acrylamide-st-thiolactone acrylamide) [PDEAEMA-b-P(NIPAAm-st-TlaAm)] copolymer and its use in controlled drug release and bio-conjugation. TlaAm units in the copolymer were ring-opened with various alkyl amines to form thiol groups (-SH), followed by thiol-ene coupling reactions with acrylamide-coated MNP and then quaternized to obtain cationic copolymer-MNP assemblies (the size < 200 nm/cluster). The use of alkyl amines having various chain lengths (e.g., 1-propylamine, 1-octylamine, or 1-dodecylamine) in the nucleophilic ring-opening reactions of the thiolactone rings affected their magnetic separation ability, water dispersibility, and release rate of doxorubicin model drug. In all cases, when increasing the temperature, they showed a thermo-responsive behavior as indicated by the decrease in hydrodynamic size and the accelerated drug release rate. These copolymer-MNP assemblies could be used as a novel platform with thermal-triggering controlled drug release and capability for adsorption with any neg. charged biomols. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).SDS of cas: 6038-19-3

The Article related to magnetite nanoparticle coating diblock copolymer controlled drug release, Plastics Manufacture and Processing: Formulating Procedures and Compositions and other aspects.SDS of cas: 6038-19-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mertens, Chiel; Aksakal, Resat; Badi, Nezha; Du Prez, Filip E. published an article in 2021, the title of the article was Sequence-defined oligoampholytes using hydrolytically stable vinyl sulfonamides: design and UCST behavior.Related Products of 6038-19-3 And the article contains the following content:

Polyampholytes, widely investigated for their distinct properties, are typically prepared via conventional polymerization techniques. This results in an ensemble of polymer chains with variation in mol. parameters such as length, ratio of charged groups and monomer order, which could influence their behavior. Here, uniform oligoampholytes with precisely positioned neg. charged carboxylate and pos. charged ammonium side-chains were synthesized using an iterative solid-phase synthesis strategy based on thiolactone chem. The amine side-chains were initially introduced via an acrylate, resulting in an amino-functionalized β-thioester that was shown to be susceptible to transesterification and hydrolysis, even under ambient conditions. While increasing the spacer length between the β-thioester and amine functionality could slow down this undesired side-reaction, it could not be completely suppressed. On the other hand, a tertiary amine-bearing vinyl sulfonamide proved to be a viable, hydrolytically stable alternative to introduce this moiety. The resulting uniform oligoampholytes are soluble in water and show UCST-type thermo responsive behavior in 85 vol% isopropanol/water mixtures The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Related Products of 6038-19-3

The Article related to hydrolytically stable vinyl sulfonamide sequence defined oligo ampholyte, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Related Products of 6038-19-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Espeel, Pieter; Goethals, Fabienne; Driessen, Frank; Nguyen, Le-Thu T.; Du Prez, Filip E. published an article in 2013, the title of the article was One-pot, additive-free preparation of functionalized polyurethanes via amine-thiol-ene conjugation.COA of Formula: C4H8ClNOS And the article contains the following content:

A one-pot, isocyanate-free method for synthesis of functionalized polyurethanes based on amine-thiol-ene conjugation is presented. Aminolysis of a readily available AB’-urethane monomer, containing both an acrylate (A) and a thiolactone unit (B’), facilitates the preparation of various reactive thiol-acrylates. In situ polymerization via Michael addition proceeds under ambient conditions, yielding polyurethanes with a large variety of chem. functionalities. Side-chain functionality originates from the modular use of different amines, allowing for the introduction of pendent functional groups (e.g. double bond, triple bond, furfuryl, tertiary amine, morpholine) along the polyurethane backbone. Extensive model studies revealed the kinetic profile of this reaction sequence and excluded the occurrence of competing reactions, such as aza-Michael addition and disulfide formation. This mild one-pot reaction requires no additives or external trigger, and the obtained polyurethanes remain soluble throughout the process, enabling post-polymerization modification in the same reaction medium. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).COA of Formula: C4H8ClNOS

The Article related to amine thiol acrylate reaction isocyanate free polyurethane synthesis, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.COA of Formula: C4H8ClNOS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics