Category: 6038-19-3

Dippe, M.; Brandt, W.; Rost, H.; Porzel, A.; Schmidt, J.; Wessjohann, L. A. published an article in 2015, the title of the article was Rationally engineered variants of S-adenosylmethionine (SAM) synthase: reduced product inhibition and synthesis of artificial cofactor homologues.Name: 3-Aminodihydrothiophen-2(3H)-one hydrochloride And the article contains the following content:

S-Adenosylmethionine (SAM) synthase was engineered for biocatalytic production of SAM and long-chain analogs by rational re-design. Substitution of two conserved isoleucine residues extended the substrate spectrum of the enzyme to artificial S-alkylhomocysteines. The variants proved to be beneficial in preparative synthesis of SAM (and analogs) due to a much reduced product inhibition. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Name: 3-Aminodihydrothiophen-2(3H)-one hydrochloride

The Article related to adenosylmethionine synthase bacillus protein engineering sam analog methylation, Enzymes: Substrates-Cofactors-Inhibitors-Activators-Coenzymes-Products and other aspects.Name: 3-Aminodihydrothiophen-2(3H)-one hydrochloride

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 18, 2018, Wilkins, Laura E.; Badi, Nezha; Du Prez, Filip; Gibson, Matthew I. published an article.Reference of 3-Aminodihydrothiophen-2(3H)-one hydrochloride The title of the article was Double-Modified Glycopolymers from Thiolactones to Modulate Lectin Selectivity and Affinity. And the article contained the following:

Multivalent glycomaterials show high affinity toward lectins but are often nonselective as they lack the precise 3-D presentation found in native glycans. Here, thiolactone chem. is exploited to enable the synthesis of glycopolymers with both a primary binding (galactose) and a variable secondary binding unit in close proximity to each other on the linker. These polymers are used to target the Cholera toxin B subunit, CTxB, inspired by its native branched glycan target, GM-1. The secondary, nonbinding unit was shown to dramatically modulate affinity and selectivity toward the Cholera toxin. These increasingly complex glycopolymers, assembled using accessible chem., can help breach the synthetic/biol. divide to obtain future glycomimetics. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Reference of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

The Article related to modified glycopolymer thiolactone lectin selectivity affinity, Chemistry of Synthetic High Polymers: Chemical Transformation Of Polymers and other aspects.Reference of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Montolio, Silvia; Zagorodko, Oleksandr; Porcar, Raul; Isabel Burguete, M.; Luis, Santiago V.; Tenhu, Heikki; Garcia-Verdugo, Eduardo published an article in 2017, the title of the article was Poly(acrylamide-homocysteine thiolactone) as a synthetic platform for the preparation of polymeric ionic liquids by post ring-opening-orthogonal modifications.Electric Literature of 6038-19-3 And the article contains the following content:

Poly(Acrylamide-Homocysteine Thiolactone) (PAHT) obtained by RAFT polymerization can be used as a starting material for the synthesis, through its post modification, of a variety of advanced polymeric materials with different morphologies and a significant structural diversity. The examples here presented illustrate the utility of this approach for the preparation of functionalized polymers containing Ionic Liquid-like units (IL-like). These Polymeric Ionic Liquids (PILs) can be designed and obtained with a careful control of their structural elements according to the needs for a specific application. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Electric Literature of 6038-19-3

The Article related to acrylamide homocysteine thiolactone polymer ionic liquid post modification, Chemistry of Synthetic High Polymers: Chemical Transformation Of Polymers and other aspects.Electric Literature of 6038-19-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 18, 2013, Reinicke, Stefan; Espeel, Pieter; Stamenovic, Milan M.; Du Prez, Filip E. published an article.HPLC of Formula: 6038-19-3 The title of the article was One-Pot Double Modification of p(NIPAAm): A Tool for Designing Tailor-Made Multiresponsive Polymers. And the article contained the following:

A quant., additive-free, and one-pot reaction cascade involving the ring-opening of a thiolactone by primary amine treatment and subsequent conversion of the released thiol groups via Michael addition to an acrylate was utilized for the double modification/functionalization of poly(N-iso-Pr acrylamide), yielding tailor-made thermoresponsive polymers. After proving a quant. double functionalization, different amine/acrylate combinations were employed to demonstrate the general applicability of the concept. Cloud points can be tuned by adjusting the amount of ring-opening amine in the reaction mixture, which enables to control the degree of modification. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).HPLC of Formula: 6038-19-3

The Article related to double modification polyacrylamide designing tailor multiresponsive polymer, Chemistry of Synthetic High Polymers: Chemical Transformation Of Polymers and other aspects.HPLC of Formula: 6038-19-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Reese, Cassandra M.; Thompson, Brittany J.; Logan, Phillip K.; Stafford, Christopher M.; Blanton, Michael; Patton, Derek L. published an article in 2019, the title of the article was Sequential and one-pot post-polymerization modification reactions of thiolactone-containing polymer brushes.Application In Synthesis of 3-Aminodihydrothiophen-2(3H)-one hydrochloride And the article contains the following content:

Thiolactone chem. has garnered significant attention as a powerful post-polymerization modification (PPM) route to mutlifunctional polymeric materials. Here, we apply this versatile chem. to the fabrication of ultrathin, multifunctional polymer surfaces via aminolysis and thiol-mediated double modifications of thiolactone-containing polymer brushes. Polymer brush surfaces were synthesized via microwave-assisted surface-initiated polymerization of DL-homocysteine thiolactone acrylamide. Aminolysis and thiol-Michael double modifications of the thiolactone-functional brush were explored using both sequential and one-pot reactions with bromobenzyl amine and 1H,1H-perfluoro-N-decyl acrylate. XPS and argon gas cluster ion sputter depth profiling enabled quant. comparison of the sequential and one-pot PPM routes with regard to conversion and spatial distribution of functional groups immobilized throughout thickness of the brush. While one-pot conditions proved to be more effective in immobilizing the amine and acrylate within the brush, the sequential reaction enabled the fabrication of multifunctional, micropatterned brush surfaces using reactive microcontact printing. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Application In Synthesis of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

The Article related to homocysteine thiolactone acrylamide polymer brush amine post polymerization, surface property wettability, Chemistry of Synthetic High Polymers: Chemical Transformation Of Polymers and other aspects.Application In Synthesis of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 2, 2020, Tian, Yi; Liu, Yibin; Su, Zhengzhou; Wang, Shenqiang; Zhang, Baoliang; Zhang, Hepeng; Zhang, Qiuyu published an article.Related Products of 6038-19-3 The title of the article was Biomimetic Brushlike Slippery Coatings with Mechanically Robust, Self-Cleaning, and Icephobic Properties. And the article contained the following:

In this work, a facile strategy was proposed to prepare a series of brushlike thermoplastic polyurethane (TPU) coatings with mech. robust, self-cleaning, and icephobic performance. Through a simple multicomponent click reaction of thiolactone with a diamine compound and mono-ethenyl-terminated polydimethylsiloxane (mono-ethenyl-PDMS), a diol with amide groups and flexible PDMS was synthesized, and a novel TPU could be obtained productively by a reaction of isocyanate and diol. The unique chain structure endowed TPU films with ascendant self-stratifying properties. During solvent vapor annealing, flexible PDMS chains migrated and enriched to the surface while urethane linkages with a strong interaction tended to locate at the substrate. Based on this, TPU-PDMS films exhibited mech. robust property, and the tensile strength value of TPU-PDMS-3 showed a sharp increase to 48.62 MPa. The resultant TPU-PDMS-10 coatings exhibited a water repellent behavior and possessed superior movability of droplet water, and also the dirt on it could be readily removed by rinsing with water without leaving any traces. Furthermore, three different criteria were used to characterize the icephobic performance. The coatings exhibited a significantly lower f.p. (approx. -27°C) of supercooled water, longer delay-icing time, and less ice adhesion shear strength. Therefore, these novel brushlike TPU coatings have tremendous potential applications. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Related Products of 6038-19-3

The Article related to biomimetic brushlike slippery coating self cleaning icephobic, pdms brushes, icephobic, liquidlike, mechanically robust, self-cleaning, thiolactone, Coatings, Inks, and Related Products: Coating Properties and Test Methods and other aspects.Related Products of 6038-19-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Celasun, Sensu; Du Prez, Filip E.; Boerner, Hans G. published an article in 2017, the title of the article was PEGylated Precision Segments Based on Sequence-Defined Thiolactone Oligomers.Application In Synthesis of 3-Aminodihydrothiophen-2(3H)-one hydrochloride And the article contains the following content:

A straightforward access route to multifunctional block copolymers, combining a poly(ethylene glycol) (PEG) block and a monodisperse segment with discrete monomer sequence based on thiolactone chem., is described. Exploiting an inverse conjugation strategy on a PEG preloaded poly(styrene) synthesis resin enables the convenient introduction of a predefined PEG-block at the α-terminus of thiolactone-based sequence-defined oligomers. Reaction conditions for the stepwise, submonomer synthesis at polar solid supports are optimized, using sequential synthesis on a model resin that enables to isolate and determine the purity of the oligomer segments by liquid chromatog.-electrospray ionization mass spectrometry anal. The reaction conditions are used to synthesize PEGylated 5mer precision polymers with defined monomer sequence in good yields and high purity to offer an interesting platform of macromols. with potential for biomedical applications. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Application In Synthesis of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

The Article related to peg conjugate thiolactone oligomer solid phase synthesis, peg conjugates, pegylation, precision polymers, sequence-defined oligomers, solid phase synthesis, Chemistry of Synthetic High Polymers: Chemical Transformation Of Polymers and other aspects.Application In Synthesis of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Driessen, Frank; Martens, Steven; De Meyer, Bernhard; Du Prez, Filip E.; Espeel, Pieter published an article in 2016, the title of the article was Double Modification of Polymer End Groups through Thiolactone Chemistry.COA of Formula: C4H8ClNOS And the article contains the following content:

A straightforward synthetic procedure for the double modification and polymer-polymer conjugation of telechelic polymers is performed through amine-thiol-ene conjugation. Thiolactone end-functionalized polymers are prepared via two different methods, through controlled radical polymerization of a thiolactone-containing initiator, or by modification of available end-functionalized polymers. Next, these different linear polymers are treated with a variety of amine/acrylate-combinations in a one-pot procedure, creating a library of tailored end-functionalized polymers. End group conversions are monitored via SEC, NMR, and MALDI-TOF anal., confirming the quant. modification after each step. Finally, this strategy is applied for the synthesis of block copolymers via polymer-polymer conjugation and the successful outcome is analyzed via LCxSEC measurements. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).COA of Formula: C4H8ClNOS

The Article related to double modification polymer end group thiolactone chem, amine-thiol-ene conjugation, end group functionalities, one-pot double modification, polymer-polymer conjugation, Chemistry of Synthetic High Polymers: Chemical Transformation Of Polymers and other aspects.COA of Formula: C4H8ClNOS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On September 14, 2021, Zhang, Jian; Li, Siyu; Wang, Zhigang; Liu, Peng; Zhao, Youliang published an article.Application of 6038-19-3 The title of the article was Multitunable Thermoresponsive and Aggregation Behaviors of Linear and Cyclic Polyacrylamide Copolymers Comprising Heterofunctional Y Junctions. And the article contained the following:

The incorporation of asym. Y junctions into thermoresponsive polymers allows access to hierarchical self-assembly, and self-assembly of cyclic polymers can further amplify the topol. effect. At present, systematic insights into the influence of Y junctions on physicochem. properties remain at the early stage. A diversity of linear and cyclic polyacrylamide copolymers with substituent-variable Y junctions are designed to reveal the effects of topol., chain length, composition, concentration, and temperature With the increasing size of substituents, copolymer aqueous solutions gradually shift from dual upper and lower critical solution temperatures (UCST/LCST) to a single LCST until the lack of phase transition. The LCST can be elevated by introduction of a cyclic architecture, longer polymer chain, and smaller substituent. Owing to the changes in degree of hydration of subunits, heat can induce sphere-vesicle-nanosheet-nanoribbon-sphere (linear copolymer) and sphere-nanosheet-nanoribbon (cyclic copolymer) transitions. In addition, the cyclization effect is also reflected in cooperative hydration of distinct subunits upon heating, higher ceiling temperatures to form stable lamellae, and more pronounced hysteresis of the turbidity curve upon cooling. This research using Y junction bearing thermoresponsive copolymers may provide a promising platform to achieve on-demand phase transitions and nanostructures. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Application of 6038-19-3

The Article related to multitunable thermoresponsive aggregation behavior linear cyclic polyacrylamide copolymer, Physical Properties of Synthetic High Polymers: Polymer Solutions and Gels and other aspects.Application of 6038-19-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On September 26, 2018, Fu, Liangbing; Zhang, Tianqi; Fu, Guanyao; Gutekunst, Will R. published an article.Name: 3-Aminodihydrothiophen-2(3H)-one hydrochloride The title of the article was Relay Conjugation of Living Metathesis Polymers. And the article contained the following:

The covalent coupling of complex macromols. is a modern challenge in both chem. and biol. The development of efficient and chemoselective methods for polymer coupling and functionalization are increasingly important for designing new advanced materials and interfacing with biochem. systems. Herein, we present a new strategy to directly conjugate living polymers prepared using ring-opening metathesis polymerization (ROMP) to both small mols. and synthetic macromols. Central to this methodol. is a terminal alkyne that serves as a directing group to promote a rapid, intramol. reaction with an otherwise unreactive olefin. This highly chemoselective relay conjugation is compatible with a range of monomer families and uses a bench-stable enyne motif that can be easily introduced to functional targets. The rapid rate of the conjugation reaction paves the way for greatly streamlined construction of complex macromol. systems derived from metathesis polymerization techniques without the need for specialized equipment. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Name: 3-Aminodihydrothiophen-2(3H)-one hydrochloride

The Article related to relay conjugation living metathesis polymer, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Name: 3-Aminodihydrothiophen-2(3H)-one hydrochloride

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics