Category: 5340-78-3

Wuckelt, Jorg published the artcileLactam analogs of pentalene. A new one-pot synthesis of pyrrolo[3,2-b]pyrrole-2,5-diones deriving from pulvinic acid, Name: Ethyltert-butylacetate, the publication is Tetrahedron Letters (1997), 38(30), 5269-5272, database is CAplus.

A new and convenient one-pot synthesis of a variety of N-aryl lactam analogs I (R¹ = Ph, 4-MeOC₆H₄, 4-O₂NC₆H₄, 3-F₃CC₆H₄, 4-MeC₆H₄, R² = Ph, CH₂Ph, CMe₃, 2-thienyl, etc.) of pentalene has been developed. Pulvinic acid dilactams I are of interest due to their electronic and optical features and as synthetic pigments.

Tetrahedron Letters published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C9H7NO2, Name: Ethyltert-butylacetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Randriamahefa, S. published the artcileImproved synthesis of tertiary alkylacetic acids and esters, SDS of cas: 5340-78-3, the publication is Synthesis (1985), 493-5, database is CAplus.

RR¹MeCCH₂CO₂H (R, R¹ = Me, Et) were prepared in 13-90% yield by treating CH₂:CCl₂ with RR¹MeCOH, H₂SO₄, and then H₂O. Similar treatment of CH₂:CCl₂ with Me₃COMe and Me₃CCl gave 55 and 77% Me₃CCH₂CO₂H resp. with some Me₃CCH₂CO₂Me also being formed when the ether was used. Addition of R²OH (R² = Me, Et, Pr, Me₂CH, Bu, Me₂CHCH₂, pentyl) to the reaction-mixture prior to H₂O yielded 13-76% RR¹CMeCH₂CO₂R².

Synthesis published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, SDS of cas: 5340-78-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Lynch, Denis published the artcileExploring the Scope of Asymmetric Synthesis of β-Hydroxy-γ-lactams via Noyori-type Reductions, Category: esters-buliding-blocks, the publication is Organic Letters (2016), 18(19), 4978-4981, database is CAplus and MEDLINE.

Enantio- and diastereoselective hydrogenation of β-keto-γ-lactams with a ruthenium-BINAP catalyst, involving dynamic kinetic resolution, has been employed to provide a general, asym. approach to β-hydroxy-γ-lactams, a structural motif common to several bioactive compounds Full conversion to the desired β-hydroxy-γ-lactams was achieved with high diastereoselectivity (up to >98% de) by addition of catalytic HCl and LiCl, while β-branching of the ketone substituent demonstrated a pronounced effect on the modest to excellent enantioselectivity (up to 97% ee) obtained.

Organic Letters published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Stack, Jeffrey G. published the artcileA new chiral auxiliary for asymmetric thermal reactions: high stereocontrol in radical addition, allylation, and annulation reactions, Formula: C8H16O2, the publication is Journal of the American Chemical Society (1992), 114(18), 7007-18, database is CAplus.

A new imide chiral auxiliary, endo-7-(2-benzoxazolyl)-1,5,7-trimethyl-3-azabicyclo[3.3.1]nonan-2-one (I), is prepared from Kemp’s triacid and resolved via its menthyl carbamate. Mixed fumarate derivatives of the auxiliary show unprecedented control of regiochem. and β-stereochem. in representative radical addition reactions. Chiral radicals derived from I also show extremely high levels of stereoselectivity in representative radical allylation and cyclization reactions. Structural features of the chiral auxiliary and features of radical addition are integrated into a model for stereoselection.

Journal of the American Chemical Society published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C18H28N2O7, Formula: C8H16O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Yang, Wenge published the artcileEffect of electron beam irradiation on volatile flavors in Tegillarca granosa meat, Category: esters-buliding-blocks, the publication is Zhongguo Shipin Xuebao (2012), 12(3), 176-184, database is CAplus.

The effect of electron beam irradiation on the volatile flavors in Tegillarca granosa meat was investigated. The volatile flavors in Tegillarca granosa meat were isolated by solid-phase microextraction and analyzed by gas chromatog./mass spectrometry after irradiation of different doses. After irradiation of 1 9kGy, the sorts of volatile flavors increased from 46 to 55, 57, 52, 58 and 66, resp. Volatile carbonyl compounds were the principal parts of volatiles, among which ketones made the contribution of sweet flower scent, while some aldehydes provided the lipid-like and fruity aromas. The unusual smell of 7 kGy group samples should be relevant to the abundant volatile carbonyl compounds The relative content of volatile alcs. increased after irradiation of 3, 5 kGy, containing some enols which might make the flavors softer. However, some kinds of olefins could to a certain extent remove the fishy smell. Electron beam irradiation brought about the increases of heterocyclic compounds Furan contributed to the fruity aromas in Tegillarca granosa meat. Besides, (S-and N-containing compounds including) pyridines and thiazoles provided the flavors of fried meat and nuts. Compared with the other exptl. groups, aromatic compounds exhibited the highest relative content with the dose of 5 kGy, among which benzaldehyde had the almond aroma, making the whole flavor of Tegillarca granosa meat better, to some degree. Electron beam irradiation with the doses of 3-5 kGy produced no significant impact on the original aromas of Tegillarca granosa meat. Furthermore, the irradiation might improve the whole flavors, to some extent.

Zhongguo Shipin Xuebao published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C11H8F2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Pritykin, L. M. published the artcileTo evaluation of the steric effect in organic compounds, Synthetic Route of 5340-78-3, the publication is Journal of Structural Chemistry (Translation of Zhurnal Strukturnoi Khimii) (2001), 41(5), 901-904, database is CAplus.

A new approach was developed to calculation of solid angles, which are a measure of steric effect in organic mols.; the approach is based on the geometrical model. The solution is implemented as a computer program.

Journal of Structural Chemistry (Translation of Zhurnal Strukturnoi Khimii) published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Synthetic Route of 5340-78-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Nishimoto, Yoshihiro published the artcileCoupling reaction of enol derivatives with silyl ketene acetals catalyzed by gallium trihalides, Recommanded Product: Ethyltert-butylacetate, the publication is Chemistry – A European Journal (2016), 22(33), 11837-11845, database is CAplus and MEDLINE.

A cross-coupling reaction between enol derivatives and silyl ketene acetals catalyzed by GaBr₃ took place to give the corresponding α-alkenyl esters. GaBr₃ showed the most effective catalytic ability, whereas other metal salts such as BF₃·OEt₂, AlCl₃, PdCl₂, and lanthanide triflates were not effective. Various types of enol ethers and vinyl carboxylates as enol derivatives are amenable to this coupling. The scope of the reaction with silyl ketene acetals was also broad. We successfully observed an alkylgallium intermediate by using NMR spectroscopy, suggesting a mechanism involving anti-carbogallation among GaBr₃, an enol derivative, and a silyl ketene acetal, followed by syn-β-alkoxy elimination from the alkylgallium. Based on kinetic studies, the turnover-limiting step of the reaction using a vinyl ether and a vinyl carboxylate involved syn-β-alkoxy elimination and anti-carbogallation, resp. Therefore, the leaving group had a significant effect on the progress of the reaction. Theor. calculations anal. suggest that the moderate Lewis acidity of gallium would contribute to a flexible conformational change of the alkylgallium intermediate and to the cleavage of the carbon-oxygen bond in the β-alkoxy elimination process, which is the turnover-limiting step in the reaction between a vinyl ether and a silyl ketene acetal.

Chemistry – A European Journal published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Recommanded Product: Ethyltert-butylacetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hirashita, Tsunehisa published the artcileA facile preparation of indium enolates and their Reformatskii- and Darzens-type reactions, Synthetic Route of 5340-78-3, the publication is Perkin 1 (2000), 825-828, database is CAplus.

Indium enolates were readily prepared by transmetalation of lithium enolates, e.g., EtO₂CCH₂R (R = H, Me, CHMe₂, CMe₃), with indium trichloride, and were subsequently reacted with aldehydes R¹CHO [R¹ = Ph, 2-HOC₆H₄, Me(CH₂)₆, (E)-PhCH:CH] to give β-hydroxy esters EtO₂CCHRCH(OH)R¹ in 48-88% yields and with moderate stereoselectivities of from 86:14 anti:syn to 67:33 syn:anti. Enolates derived from Me bromoacetate undergo deprotonation with LDA in the presence of indium trichloride followed by addition to aldehydes R¹CHO [R¹ = Ph, Me(CH₂)₆, (E)-PhCH:CH] or acetophenone to give epoxy esters such as I [R = H, Me; R¹ = Ph, Me(CH₂)₆, (E)-PhCH:CH] in 23-80% yields with selectivities of 52:48 to 82:18 for the trans-epoxide stereoisomers. Phenacyl bromide undergoes self-condensation in the presence of indium trichloride under the standard coupling conditions; when lithium dicyclohexylamide was added to benzaldehyde, phenacyl chloride, and indium trichloride in THF, the Darzens condensation product was isolated solely as the trans stereoisomer in 77% yield.

Perkin 1 published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Synthetic Route of 5340-78-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sjoholm, Asa published the artcileInvestigation of the Lewis acid mediated stereoselective cyclization of cationic aminyl radicals leading to substituted pyrrolidines, Formula: C8H16O2, the publication is Journal of the Chemical Society, Perkin Transactions 1 (2001), 891-899, database is CAplus.

Stereoselective Lewis acid mediated radical cyclizations of variously substituted N-chloropentenylamines afforded the corresponding pyrrolidines with good to excellent diastereoselectivities and in high yields. Several Lewis acids have been screened in an attempt to find an efficient and stereoselective protocol for the formation of pyrrolidines; no apparent correlation between the different Lewis acids and the selectivities obtained was observed

Journal of the Chemical Society, Perkin Transactions 1 published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C16H24BF4Ir, Formula: C8H16O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ha, Deok Chan published the artcileN-Trimethylsilylimines: applications to the syntheses of β-lactams, Formula: C8H16O2, the publication is Journal of the American Chemical Society (1984), 106(17), 4819-25, database is CAplus.

Ester enolates and N-trimethylsilylimines react to afford β-lactams. The stereochem. course of the reaction depends on the ester enolate geometry. Thus, (E)-enolates give mainly cis β-lactams while (Z)-enolates give ∼1:1 mixtures of cis and trans β-lactams. The use of HOCHMeCH₂CO₂Et as the ester component gives β-lactams of potential use in carbapenem synthesis. The differences in the behavior of N-trimethylsilyl and N-arylimines in the ester-imine condensations are also discussed.

Journal of the American Chemical Society published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Formula: C8H16O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics