Category: 2253-73-8

Biosynthesis of Cu/KF/Clinoptilolite@MWCNTs nanocomposite and its application as a recyclable nanocatalyst for the synthesis of new Schiff base of benzoxazine derivatives and reduction of organic pollutants was written by Hamedani, Naghmeh Faal;Hargalani, Fariba Zamani;Rostami-Charati, Faramarz. And the article was included in Molecular Diversity in 2022.Electric Literature of C4H7NS The following contents are mentioned in the article:

A new Schiff base of benzoxazine derivativesI (R = ethoxycarbonyl, CN; R¹ = i-Pr, Ph, Bn, etc.; R² = Me, Et; R³ = H, OMe, Me, OH; R⁴ = H, Me) in excellent yields using multicomponent reactions of phthalaldehyde or its derivatives2-CHO3-R³-5-R⁴-C₆H₂CHO primary amines RCH₂NH₂, isothiocyanates R¹N=C=S, 2,4-dihydroxyacetophenone, isopropenylacetylene and Me or Et amine in the presence of catalytic amount of Cu/KF/CP@MWCNTs NCs in water at room temperature were synthesized. Also, the catalytic activity of the green synthesized Cu/KF/CP@MWCNTs NCs was evaluated in the reduction in organic pollutants such as 4-nitrophenol (4-NP) in water at mild conditions. The results indicated that the biosynthesized NCs have very high and effective catalytic activity for organic pollutants within few seconds. As well the antioxidant activity of some synthesized benzoxazine was studied using trapping of radical by DPPH and ferric reduction activity potential (FRAP) experiment The short time of reaction, high yields of product, easy separation of catalyst and products are some benefits of this procedure. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Electric Literature of C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Electric Literature of C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Biosynthesis of Cu/KF/Clinoptilolite@MWCNTs nanocomposite and its application as a recyclable nanocatalyst for the synthesis of new Schiff base of benzoxazine derivatives and reduction of organic pollutants was written by Hamedani, Naghmeh Faal;Hargalani, Fariba Zamani;Rostami-Charati, Faramarz. And the article was included in Molecular Diversity in 2022.SDS of cas: 2253-73-8 The following contents are mentioned in the article:

A new Schiff base of benzoxazine derivativesI (R = ethoxycarbonyl, CN; R¹ = i-Pr, Ph, Bn, etc.; R² = Me, Et; R³ = H, OMe, Me, OH; R⁴ = H, Me) in excellent yields using multicomponent reactions of phthalaldehyde or its derivatives2-CHO3-R³-5-R⁴-C₆H₂CHO primary amines RCH₂NH₂, isothiocyanates R¹N=C=S, 2,4-dihydroxyacetophenone, isopropenylacetylene and Me or Et amine in the presence of catalytic amount of Cu/KF/CP@MWCNTs NCs in water at room temperature were synthesized. Also, the catalytic activity of the green synthesized Cu/KF/CP@MWCNTs NCs was evaluated in the reduction in organic pollutants such as 4-nitrophenol (4-NP) in water at mild conditions. The results indicated that the biosynthesized NCs have very high and effective catalytic activity for organic pollutants within few seconds. As well the antioxidant activity of some synthesized benzoxazine was studied using trapping of radical by DPPH and ferric reduction activity potential (FRAP) experiment The short time of reaction, high yields of product, easy separation of catalyst and products are some benefits of this procedure. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8SDS of cas: 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. SDS of cas: 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as possible anticancer agents was written by Cevik, Ulviye Acar;Osmaniye, Derya;Levent, Serkan;Saglik, Begum Nurpelin;Cavusoglu, Betul Kaya;Karaduman, Abdullah Burak;Ozkay, Yusuf;Kaplancikli, Zafer Asim. And the article was included in Acta Pharmaceutica (Warsaw, Poland) in 2020.Name: Isopropylisothiocyanate The following contents are mentioned in the article:

The synthesis of new N-(5-substituted-1,3,4-thiadiazol-2-yl)-2-[(5-(substituted amino)-1,3,4-thiadiazol-2-yl)thio]acetamide derivatives and investigation of their anticancer activities were the aims of this work. All the new compounds′ structures were elucidated by elemental analyses, IR, ¹H NMR, ¹³C NMR and MS spectral data. Anticancer activity studies of the compounds were evaluated against MCF-7 and A549 tumor cell lines. In addition, with the purpose of determining the selectivity of cytotoxic activities, the most active compound was screened against a noncancer NIH3T3 cell line (mouse embryonic fibroblast cells). Among the tested compounds, compound 4y (N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-((5-(p-tolylamino)-1,3,4-thiadiazol-2-yl)thio)acetamide), showed promising cytotoxic activity against MCF7 cancer cell with an IC₅₀ value of 0.084 ± 0.020 mmol L^-1 and against A549 cancer cell with IC₅₀ value of 0.034 ± 0.008 mmol L^-1, compared with cisplatin. The aromatase inhibitory activity was evaluated for compound 4y on MCF-7 cell line showing promising activity with IC₅₀ of 0.062 ± 0.004 mmol L^-1. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Name: Isopropylisothiocyanate).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Name: Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as possible anticancer agents was written by Cevik, Ulviye Acar;Osmaniye, Derya;Levent, Serkan;Saglik, Begum Nurpelin;Cavusoglu, Betul Kaya;Karaduman, Abdullah Burak;Ozkay, Yusuf;Kaplancikli, Zafer Asim. And the article was included in Acta Pharmaceutica (Warsaw, Poland) in 2020.Related Products of 2253-73-8 The following contents are mentioned in the article:

The synthesis of new N-(5-substituted-1,3,4-thiadiazol-2-yl)-2-[(5-(substituted amino)-1,3,4-thiadiazol-2-yl)thio]acetamide derivatives and investigation of their anticancer activities were the aims of this work. All the new compounds′ structures were elucidated by elemental analyses, IR, ¹H NMR, ¹³C NMR and MS spectral data. Anticancer activity studies of the compounds were evaluated against MCF-7 and A549 tumor cell lines. In addition, with the purpose of determining the selectivity of cytotoxic activities, the most active compound was screened against a noncancer NIH3T3 cell line (mouse embryonic fibroblast cells). Among the tested compounds, compound 4y (N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-((5-(p-tolylamino)-1,3,4-thiadiazol-2-yl)thio)acetamide), showed promising cytotoxic activity against MCF7 cancer cell with an IC₅₀ value of 0.084 ± 0.020 mmol L^-1 and against A549 cancer cell with IC₅₀ value of 0.034 ± 0.008 mmol L^-1, compared with cisplatin. The aromatase inhibitory activity was evaluated for compound 4y on MCF-7 cell line showing promising activity with IC₅₀ of 0.062 ± 0.004 mmol L^-1. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Related Products of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Related Products of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Glucosinolates in Sisymbrium officinale (L.) Scop.: comparative analysis in cultivated and wild plants and in vitro assays with T2Rs bitter taste receptors was written by Borgonovo, Gigliola;Zimbaldi, Nathan;Guarise, Marta;Bedussi, Floriana;Winnig, Marcel;Vennegeerts, Timo;Bassoli, Angela. And the article was included in Molecules in 2019.HPLC of Formula: 2253-73-8 The following contents are mentioned in the article:

Sisymbrium officinale (L.) Scop., commonly known as “hedge mustard” or “the singer’s plant” is a wild plant common in Eurasian regions. Its cultivation is mainly dedicated to herboristic applications and it has only recently been introduced into Italy. The active botanicals in S. officinale are glucosinolates, generally estimated by using UV or high-performance liquid chromatog. (HPLC). Using both techniques, we measured the total glucosinolates from S. officinale in different parts of the plant as roots, leaves, seeds, and flowers. A comparison was made for cultivated and wild samples, and for samples obtained with different pre-treatment and fresh, frozen, and dried storage conditions. Cultivated and wild plants have a comparable amount of total glucosinolates, while drying procedures can reduce the final glucosinolates content. The content in glucoputranjivin, which is the chem. marker for glucosinolates in S. officinale, has been determined using HPLC and a pure reference standard Glucoputranjivin and two isothiocyanates from S. officinale have been submitted to in vitro assays with the platform of bitter taste receptors of the T2Rs family. The results show that glucoputranjivin is a selective agonist of receptor T2R16. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8HPLC of Formula: 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.HPLC of Formula: 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Glucosinolates in Sisymbrium officinale (L.) Scop.: comparative analysis in cultivated and wild plants and in vitro assays with T2Rs bitter taste receptors was written by Borgonovo, Gigliola;Zimbaldi, Nathan;Guarise, Marta;Bedussi, Floriana;Winnig, Marcel;Vennegeerts, Timo;Bassoli, Angela. And the article was included in Molecules in 2019.Related Products of 2253-73-8 The following contents are mentioned in the article:

Sisymbrium officinale (L.) Scop., commonly known as “hedge mustard” or “the singer’s plant” is a wild plant common in Eurasian regions. Its cultivation is mainly dedicated to herboristic applications and it has only recently been introduced into Italy. The active botanicals in S. officinale are glucosinolates, generally estimated by using UV or high-performance liquid chromatog. (HPLC). Using both techniques, we measured the total glucosinolates from S. officinale in different parts of the plant as roots, leaves, seeds, and flowers. A comparison was made for cultivated and wild samples, and for samples obtained with different pre-treatment and fresh, frozen, and dried storage conditions. Cultivated and wild plants have a comparable amount of total glucosinolates, while drying procedures can reduce the final glucosinolates content. The content in glucoputranjivin, which is the chem. marker for glucosinolates in S. officinale, has been determined using HPLC and a pure reference standard Glucoputranjivin and two isothiocyanates from S. officinale have been submitted to in vitro assays with the platform of bitter taste receptors of the T2Rs family. The results show that glucoputranjivin is a selective agonist of receptor T2R16. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Related Products of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Related Products of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Saturated red iridium(III) complexes containing a unique four-membered Ir-S-C-N backbone: mild synthesis and application in OLEDs was written by Lu, Guangzhao;Yao, Jingwen;Chen, Zhanxiang;Ma, Dongge;Yang, Chuluo. And the article was included in Journal of Materials Chemistry in 2020.Application of 2253-73-8 The following contents are mentioned in the article:

New Ir(III) cyclometalated complexes (4tfmpiq)₂Ir(tiptha), (4tfmpiq)₂Ir(phdiptha), (4tfmpiq)₂Ir(fphdiptha) and (4tfmpiq)₂Ir(ipdptha) (4tfmpiq = 4-(4-(trifluoromethyl)phenyl)isoquinoline, tiptha = 1,1,3-triisopropylthiourea, phdiptha = 1,1-diisopropyl-3-phenylthiourea, fphdiptha = 3-(4-fluorophenyl)-1,1-diisopropylthiourea, ipdptha = 3-isopropyl-1,1-diphenylthiourea) containing a unique four-membered ring Ir-S-C-N backbone were facilely synthesized under mild conditions. By introducing different substituents such as iso-Pr, Ph, 4-fluorophenyl, diisopropylamine and diphenylamine on the thiourea ancillary ligands, not only the S-C-N ligands can be extensively derived, but also the emission colors (λ_peak = 627-636 nm) and photoluminescence quantum efficiencies (Φ_P = 38.0-42.0%) can be regulated. Employing these complexes as emitters, the organic light emitting diodes (OLEDs) exhibited good performances with a maximum external quantum efficiency (EQE_max) of 13.1% for saturated red emission with CIE coordinates of (0.68, 0.32). These results demonstrate the great potential of the S-C-N ancillary ligands for developing new Ir(III) complexes towards OLED applications. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Application of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Application of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Saturated red iridium(III) complexes containing a unique four-membered Ir-S-C-N backbone: mild synthesis and application in OLEDs was written by Lu, Guangzhao;Yao, Jingwen;Chen, Zhanxiang;Ma, Dongge;Yang, Chuluo. And the article was included in Journal of Materials Chemistry in 2020.Product Details of 2253-73-8 The following contents are mentioned in the article:

New Ir(III) cyclometalated complexes (4tfmpiq)₂Ir(tiptha), (4tfmpiq)₂Ir(phdiptha), (4tfmpiq)₂Ir(fphdiptha) and (4tfmpiq)₂Ir(ipdptha) (4tfmpiq = 4-(4-(trifluoromethyl)phenyl)isoquinoline, tiptha = 1,1,3-triisopropylthiourea, phdiptha = 1,1-diisopropyl-3-phenylthiourea, fphdiptha = 3-(4-fluorophenyl)-1,1-diisopropylthiourea, ipdptha = 3-isopropyl-1,1-diphenylthiourea) containing a unique four-membered ring Ir-S-C-N backbone were facilely synthesized under mild conditions. By introducing different substituents such as iso-Pr, Ph, 4-fluorophenyl, diisopropylamine and diphenylamine on the thiourea ancillary ligands, not only the S-C-N ligands can be extensively derived, but also the emission colors (λ_peak = 627-636 nm) and photoluminescence quantum efficiencies (Φ_P = 38.0-42.0%) can be regulated. Employing these complexes as emitters, the organic light emitting diodes (OLEDs) exhibited good performances with a maximum external quantum efficiency (EQE_max) of 13.1% for saturated red emission with CIE coordinates of (0.68, 0.32). These results demonstrate the great potential of the S-C-N ancillary ligands for developing new Ir(III) complexes towards OLED applications. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Product Details of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Product Details of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Design, synthesis and fungicidal activity of novel strobilurin-1,2,4-triazole derivatives containing furan or thiophene rings was written by Liu, Yang;Liu, Ming;Zhang, Dongkai;Hua, Xuewen;Wang, Baolei;Zhou, Sha;Li, Zhengming. And the article was included in Chemical Research in Chinese Universities in 2016.Safety of Isopropylisothiocyanate The following contents are mentioned in the article:

A series of strobilurin-1,2,4-triazole derivatives containing a furan or thiophene ring I (R¹ = H, Br; R² = Me, i-Pr, Ph, Bn, etc.; X = O, S) was designed and synthesized. The bioassays indicated that the fungicidal activities of compounds I [R¹ = H, R² = Et, X = O (II)] (EC₅₀ = 14.82 mg/L) and I [R¹ = H, R² = i-Pr, X = O (III)] (EC₅₀ = 18.72 mg/L) against Cercospora arachidicola Hori in vitro were much higher than that of Azoxystrobin as control (EC₅₀ = 40.54 mg/L) and the fungicidal activities of compounds I (R¹ = H, R² = i-Bu, X = S) (EC₅₀ = 8.66 mg/L) and I [R¹ = Br, R² = n-Bu, X = O (IV)] (EC₅₀ = 9.89 mg/L) against Rhizoctonia cerealis in vitro were higher than that of the same control (EC₅₀ = 10.86 mg/L). Compounds I (R¹ = Br, R² = i-Pr, X = O), II, III, and IV could be considered as the leading compounds for further investigation. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Safety of Isopropylisothiocyanate).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Safety of Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effects of horseradish oil and eight isothiocyanates vapour treatment on postharvest disease control and their efficacy as preservatives of mature green tomato was written by Ren, Jing-Jing;Zhang, Dan;Hou, Pu-Xing;Wu, Hua. And the article was included in Plant Disease in 2020.Related Products of 2253-73-8 The following contents are mentioned in the article:

This study evaluated the potential of horseradish (Armoracia rusticana) oil (ARO) and eight isothiocyanates (Pr ITC [ProITC], iso-Pr ITC [IsoproITC], Bu ITC [n-BuITC], 3-butenyl ITC [3-BeITC], Ph ITC [PhITC], benzyl ITC [BzITC], 2-phenylethyl ITC [PhEITC], and allyl ITC [AITC]) as preservatives and antifungal agents for postharvest tomato disease control. Results showed that ARO and eight ITCs demonstrated antifungal activities against Botrytis cinerea, Alternaria alternata, Rhizopus stolonifer, and Geotrichum candidum, which can cause the decay of mature green tomato during storage. Allyl-ITC (AITC) had the lowest EC50 values of mycelia growth suppression, with 0.18, 0.44, 0.29, and 0.43μg/mL air for B. cinerea, A. alternata, R. stolonifer, and G. candidum, resp. ARO, 2-PhEITC, BzITC, and AITC exhibited better efficacy as preservatives of mature green tomato than other ITCs on the basis of some parameters, such as low decay rate, slow reduction in weight loss, slight change in hardness, slow decrease in acidity, and total soluble solid content of treated tomatoes. GC-MS revealed that 2-PhEITC (77.78%) and AITC (15.87%) were the major components of ARO. These results can be used as a basis to develop preservative products composed of ITCs. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Related Products of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Related Products of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics