Category: 2253-73-8

4-(N-Boc-amino)-1H-1,2,3-triazolecarbothioamides in the synthesis of a new heterocyclic [1,2,3]triazolo[4,5-e][1,4]thiazepine system was written by Syrota, Natalia A.;Kemskiy, Sergiy V.;Bol’but, Andriy V.;Chernobaev, Igor I.;Liavinets, Oleksandr S.;Vovk, Mykhailo V.. And the article was included in Chemistry of Heterocyclic Compounds in 2021.Synthetic Route of C4H7NS The following contents are mentioned in the article:

4-(N-Boc-amino)-1H-1,2,3-triazolecarbothioamides I [R¹ = Me, Ph, 2-MeOC₆H₄, H₂CH₂CPh; R² = Et, i-Pr, t-Bu, cyclohexyl] , obtained by a sequential treatment of 4-(N-Boc-amino)-1H-1,2,3-triazoles with n-BuLi and alkyl isothiocyanates at -78 and -60°C, reacted with Et bromoacetate, forming the resp. 4-(N-Boc-amino)-5-thioimidates II , which underwent intramol. cyclocondensation upon treatment in saturated HCl solution in dioxane, producing 8-(alkylimino)-4,8-dihydro-1H-[1,2,3]triazolo[4,5-e][1,4]thiazepin-5(6H)-ones III. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Synthetic Route of C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Synthetic Route of C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

H₂O₂-Mediated Synthesis of 1,2,4-Thiadiazole Derivatives in Ethanol at Room Temperature was written by Cao, Xian-Ting;Zheng, Zuo-Ling;Liu, Jie;Hu, Yu-He;Yu, Hao-Yun;Cai, Shasha;Wang, Guannan. And the article was included in Advanced Synthesis & Catalysis in 2022.COA of Formula: C4H7NS The following contents are mentioned in the article:

Herein, the H₂O₂-mediated synthesis of 1,2,4-thiadiazole derivatives under metal-free conditions at room temperature with ethanol as the sole solvent was reported. Various substrates could undergo the reaction smoothly, providing the expected yields of the desired products. Moreover, the target products were obtained by filtration or extraction instead of column chromatog., which requires a large amount of organic solution and silica gel during purification The developed synthetic method can be potentially applied in the large-scale preparation of 1,2,4-thiadiazole derivatives as agrochems., pharmaceuticals, and functional materials. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8COA of Formula: C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.COA of Formula: C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

H₂O₂-Mediated Synthesis of 1,2,4-Thiadiazole Derivatives in Ethanol at Room Temperature was written by Cao, Xian-Ting;Zheng, Zuo-Ling;Liu, Jie;Hu, Yu-He;Yu, Hao-Yun;Cai, Shasha;Wang, Guannan. And the article was included in Advanced Synthesis & Catalysis in 2022.COA of Formula: C4H7NS The following contents are mentioned in the article:

Herein, the H₂O₂-mediated synthesis of 1,2,4-thiadiazole derivatives under metal-free conditions at room temperature with ethanol as the sole solvent was reported. Various substrates could undergo the reaction smoothly, providing the expected yields of the desired products. Moreover, the target products were obtained by filtration or extraction instead of column chromatog., which requires a large amount of organic solution and silica gel during purification The developed synthetic method can be potentially applied in the large-scale preparation of 1,2,4-thiadiazole derivatives as agrochems., pharmaceuticals, and functional materials. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8COA of Formula: C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.COA of Formula: C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bioorthogonal Click and Release Reaction of Iminosydnones with Cycloalkynes was written by Bernard, Sabrina;Audisio, Davide;Riomet, Margaux;Bregant, Sarah;Sallustrau, Antoine;Plougastel, Lucie;Decuypere, Elodie;Gabillet, Sandra;Kumar, Ramar Arun;Elyian, Jijy;Trinh, Minh Nguyet;Koniev, Oleksandr;Wagner, Alain;Kolodych, Sergii;Taran, Frederic. And the article was included in Angewandte Chemie, International Edition in 2017.Product Details of 2253-73-8 The following contents are mentioned in the article:

We report the discovery of a new bioorthogonal click-and-release reaction involving iminosydnones and strained alkynes (e.g., I + II �III + N-benzylurea). This transformation leads to two products resulting from the ligation and fragmentation of iminosydnones under physiol. conditions. Optimized iminosydnones were successfully used to design innovative cleavable linkers for protein modification, thus opening up new areas in the fields of drug release and target-fishing applications. This click-and-release technol. offers the possibility of exchanging tags on proteins for functionalized cyclooctynes under mild and bioorthogonal conditions. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Product Details of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Product Details of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chemical composition of essential oil of Excoecaria acerifolia collected from Kumaun Himalayas was written by Rawat, Kavita;Parasad, Kundan;Bisht, Ganga. And the article was included in World Journal of Pharmaceutical Research in 2017.Computed Properties of C4H7NS The following contents are mentioned in the article:

The hydro-distilled essential oil of Excocaria acerifolia has been examined by means of gas chromatog.-mass spectrometry (GC-MS). The oil constituents were identified according to their mass spectra and their relative retention indexes determined on a non-polar stationary phase capillary column. Fifty-seven constituents have been identified representing 93.37% of the total oil. The main compounds in major amounts were Iso-Pr isothiocyanate (14.03%), (E)- Caryophyllen (11.65%), Benzyl isothiocyanate (9.32%), 1, 3, 8- paramenthatriene (6.61%), the compound in trace or in minor amount were n-hexanol (0.06%), 2-Ethyl-5-Me THF (0.06%), the oil was found rich in oxygenated mono and sesquiterpene hydrocarbons. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Computed Properties of C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Computed Properties of C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and Coordination Chemistry of 3,4-Ethylene-Bridged 1,1,2,5-Tetrasubstituted Biguanides was written by Dehmel, Maximilian;Vass, Valentin;Prock, Lukas;Goerls, Helmar;Kretschmer, Robert. And the article was included in Inorganic Chemistry in 2020.COA of Formula: C4H7NS The following contents are mentioned in the article:

The synthesis of 3,4-ethylene-bridged 1,1,2,5-tetrasubstituted biguanides is reported, which are accessible by three alternative routes. Exemplary mol. structures of the ligand and an observed side product have been elucidated by x-ray diffraction anal. Mono- and dinuclear complexes of the biguanide in both its neutral and monoanionic forms were obtained, including examples of aluminum, copper, magnesium, potassium, tin, and zinc, indicating a versatile coordination behavior, as evidenced by single-crystal x-ray diffraction anal. A new class of electron-rich N,N’-bidentate ligands is reported, and mono- and dinuclear complexes of the new ligand in both its neutral and monoanionic form were obtained. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8COA of Formula: C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.COA of Formula: C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and Coordination Chemistry of 3,4-Ethylene-Bridged 1,1,2,5-Tetrasubstituted Biguanides was written by Dehmel, Maximilian;Vass, Valentin;Prock, Lukas;Goerls, Helmar;Kretschmer, Robert. And the article was included in Inorganic Chemistry in 2020.Name: Isopropylisothiocyanate The following contents are mentioned in the article:

The synthesis of 3,4-ethylene-bridged 1,1,2,5-tetrasubstituted biguanides is reported, which are accessible by three alternative routes. Exemplary mol. structures of the ligand and an observed side product have been elucidated by x-ray diffraction anal. Mono- and dinuclear complexes of the biguanide in both its neutral and monoanionic forms were obtained, including examples of aluminum, copper, magnesium, potassium, tin, and zinc, indicating a versatile coordination behavior, as evidenced by single-crystal x-ray diffraction anal. A new class of electron-rich N,N’-bidentate ligands is reported, and mono- and dinuclear complexes of the new ligand in both its neutral and monoanionic form were obtained. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Name: Isopropylisothiocyanate).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Name: Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Efficient synthesis of unsymmetrical trisubstituted 1,3,5-triazines catalyzed by hemoglobin was written by Li, Fengxi;Wang, Chunyu;Xu, Yaning;Zhao, Zixian;Su, Jiali;Luo, Chenhan;Ning, Yujie;Li, Zhengqiang;Li, Chen;Wang, Lei. And the article was included in Molecular Catalysis in 2021.Category: esters-buliding-blocks The following contents are mentioned in the article:

In this work, a green and efficient process for the synthesis of unsym. trisubstituted 1,3,5-triazines from isothiocyanate with amidines and 1,1,3,3-tetramethylguanidine was developed. Under optimal conditions (isothiocyanate (0.1 mmol), amidines (0.1 mmol), 1,1,3,3-tetramethylguanidine (0.1 mmol), DMSO (1 mL), hemeprotein (heme concentration: 0.05 mol%), TBHP (3 equiv), room temperature, 10 min), high yields of 1,3,5-triazines (81%-96%) was obtained when HbRb (Hb from rabbit blood) was used as the catalyst. This enzymic method demonstrates the great potential for the synthesis of unsym. trisubstituted 1,3,5-triazines and extends the application of enzyme catalytic promiscuity in organic synthesis. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Category: esters-buliding-blocks).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Efficient synthesis of unsymmetrical trisubstituted 1,3,5-triazines catalyzed by hemoglobin was written by Li, Fengxi;Wang, Chunyu;Xu, Yaning;Zhao, Zixian;Su, Jiali;Luo, Chenhan;Ning, Yujie;Li, Zhengqiang;Li, Chen;Wang, Lei. And the article was included in Molecular Catalysis in 2021.Synthetic Route of C4H7NS The following contents are mentioned in the article:

In this work, a green and efficient process for the synthesis of unsym. trisubstituted 1,3,5-triazines from isothiocyanate with amidines and 1,1,3,3-tetramethylguanidine was developed. Under optimal conditions (isothiocyanate (0.1 mmol), amidines (0.1 mmol), 1,1,3,3-tetramethylguanidine (0.1 mmol), DMSO (1 mL), hemeprotein (heme concentration: 0.05 mol%), TBHP (3 equiv), room temperature, 10 min), high yields of 1,3,5-triazines (81%-96%) was obtained when HbRb (Hb from rabbit blood) was used as the catalyst. This enzymic method demonstrates the great potential for the synthesis of unsym. trisubstituted 1,3,5-triazines and extends the application of enzyme catalytic promiscuity in organic synthesis. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Synthetic Route of C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mass spectra of new heterocycles: XV. Fragmentation of 1-substituted 3-alkoxy-2-(propargylsulfanyl)- and 3-alkoxy-2-(allenylsulfanyl)-1H-pyrroles under electron impact was written by Klyba, L. V.;Tarasova, O. A.;Nedolya, N. A.. And the article was included in Russian Journal of Organic Chemistry in 2016.Name: Isopropylisothiocyanate The following contents are mentioned in the article:

The electron impact mass spectra of 1-R-substituted 3-alkoxy-2-(propargylsulfanyl)- and 3-alkoxy-2-(allenylsulfanyl)-1H-pyrroles (R = Me, i-Pr, s-Bu, Ph) have been studied for the first time. These compounds give rise to stable mol. ions whose primary fragmentation follows three competing pathways: cleavage of the C-O bonds with expulsion of alkyl radical, cleavage of the C-S bonds with formation of [M-C₃H₃]⁺ ions, and cleavage of the C-N bonds with synchronous hydrogen transfer to give odd-electron [M-C_nH_2n]+ · ion. The main fragmentation pathway of 2-(propargylsulfanyl) derivatives is cleavage of the C-S bond with formation of [M-C₃H₃]⁺ ion. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Name: Isopropylisothiocyanate).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Name: Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics