Category: 1985-51-9

On September 30, 2013, Shehata, Mohamed; Durner, Juergen; Eldenez, Ayce; Van Landuyt, Kirsten; Styllou, Panorea; Rothmund, Lena; Hickel, Reinhard; Scherthan, Harry; Geurtsen, Werner; Kaina, Bernd; Carell, Thomas; Reichl, Franz X. published an article.Safety of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate) The title of the article was Cytotoxicity and induction of DNA double-strand breaks by components leached from dental composites in primary human gingival fibroblasts. And the article contained the following:

The public interest steadily increases in the biol. adverse effects caused by components released from resin-based dental restorations. In this study, the cytotoxicity and the genotoxicity were investigated of following released components from dental resin restorations in human gingival fibroblasts (HGF): tetraethyleneglycol dimethacrylate (TEEGDMA), neopentylglycol dimethacrylate (Neopen), diphenyliodoniumchloride (DPIC), triphenyl-stibane (TPSB) and triphenylphosphane (TPP). XTT based cell viability assay was used for cytotoxicity screening of substances. γ-H2AX assay was used for genotoxicity screening. In the γ-H2AX assay, HGFs were exposed to the substances for 6 h. Induced foci represent double DNA strand breaks (DSBs), which can induce ATM-dependent phosphorylation of the histone H2AX. Cell death effects (apoptosis and necrosis), induced by the substances were visually tested by the same investigator using the fluorescent microscope. All tested substances induced a dose-dependent loss of viability in HGFs. Following toxicity ranking among the substances at EC50-concentration were found in the XTT assay (mM, mean ± SEM; n = 5): DPIC > Neopen > TPSB > TPP > TEEGDMA. DSB-foci per HGF-cell were obtained, when HGFs were exposed to the EC50-concentration of each substance in the following order (mean ± SEM; n = 3): DPIC > Neopen > TPSB > TPP > TEEGDMA. Multi-foci cells (cells that contain more than 40 foci each) in 80 HGF-cells at EC50-concentration of each substance were found as follow (mean ± SEM; n = 3): DPIC > Neopen > TPP > TPSB > TEEGDMA. Cell apoptosis contained in each substance at EC50-concentration in the following order (mean ± SEM; n = 3): DPIC > Neopen > TPSB > TPP >TEEGDMA. Cell necrosis contained in each substance at EC50-concentration in the following order (mean ± SEM; n = 3): DPIC > Neopen > TPSB > TPP > TEEGDMA. Leached components from dental resin restorations can induce DNA DSBs and cell death effects in HGFs. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Safety of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

The Article related to cytotoxicity genotoxicity gingival fibroblast dental composite resin restorative material, teegdma neopen dpic tpsb tpp dna double strand break, composite, dpic, hgf, neopen, teegma, tpp, tpsb, γ-h2ax assay and other aspects.Safety of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Makuuchi, Keizo; Yoshii, Fumio; Abe, Toshihiko published an article in 1975, the title of the article was Radiation effects on poly(vinylidene fluoride). V. Radiation-induced crosslinking of poly(vinylidenefluoride) in the presence of polyfunctional monomers.Reference of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate) And the article contains the following content:

When poly(vinylidene fluoride) (I) [24937-79-9] containing 10% mono- or polyfunctional acrylate or methacrylate was compression-molded at 210° and the sheets were irradiated with electron beams, the crosslinking efficiency of the monomers (14 used) increased in the order of monofunctional monomers < linear difunctional monomers < branched difunctional monomers < trifunctional monomers. Among a group of monomers with similar functionality, monomers having greater compatibility with I had higher crosslinking efficiency, and acrylates were poorer crosslinking agents than corresponding methacrylates because of the homopolymerization during molding. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Reference of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

The Article related to polyvinylidene fluoride crosslinking, acrylate crosslinking polyvinylidene fluoride, methacrylate crosslinking polyvinylidene fluoride, radiochem crosslinking polyvinylidene fluoride, electron beam crosslinking and other aspects.Reference of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 31, 1989, Sivergin, Yu. M.; Grachev, A. V.; Shashkova, V. T.; Usmanov, S. M. published an article.Application of 1985-51-9 The title of the article was Investigation of the compressibility of oligoester (meth)acrylates. And the article contained the following:

The compressibility of oligoester (meth)acrylates, such as CH2:C(R)CO2(CH2)nOCOC(R):CH2 (R = H, Me; n = 2, 4, 6, 10) and diethylene glycol dimethacrylate, and the compressibility isotherms of the monomers were determined with respect to polymerization The pressure necessary for crystallization of the monomers decreased with increasing length of the (CH2) chain. Compression of the liquid monomers resulted not only in reduction of the free volume, but also in reduction of the volume of the mol. The effects of loading cycles on the compressibility isotherms are discussed briefly. The begin of polymerization ethylene glycol dimethacrylate was at 0.2-0.25 GPa and was reflected in the compressibility isotherm curves. The suitability of polymerization of oligoester (meth)acrylates is discussed briefly. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Application of 1985-51-9

The Article related to compressibility oligoester methacrylate polymerization, acrylate oligoester compressibility polymerization, isotherm compressibility oligoester methacrylate monomer, ethylene glycol dimethacrylate polymerization and other aspects.Application of 1985-51-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 31, 1984, Fujisawa, Seiichiro; Kadoma, Yoshinori; Masuhara, Eiichi published an article.Related Products of 1985-51-9 The title of the article was A calorimetric study of the interaction of synthetic phospholipid liposomes with vinyl monomers, acrylates and methacrylates. And the article contained the following:

Mono-, di-, and trimethacrylates (monomers) are widely used in dentistry as restorative materials, adhesives, prosthetic devices, etc. Residual monomers released from the cured resin have been implicated in toxicol. effects. To monitor the biol. actions at the membrane level induced by monomers, the changes in the phase transition temperature (T) and enthalpy (ΔH) of dipalmitoylphosphatidylcholine  [2644-64-6] liposomes induced by 37 different monomers were studied by DSC. The monomers that caused large changes in the T and ΔH were vinyl monomers, acrylates, monomethacrylates that contain hydroxy, carbonyl, amino, and Ph groups, dimethacrylates with short-chain substituents, and aliphatic trimethacrylates. The changes in the T and ΔH values may be due not only to hydrophobic interactions, but also to interactions induced by the double bonds or the functional groups in the monomers. On the other hand, methacrylates with simple alkyl ester linkage and dimethacrylates with bisphenol A groups exhibited the smallest effects. The changes in the T and ΔH induced by highly hydrophobic methacrylates were small due to their slower interaction. These changes in transition properties of liposomes seem to be related to biol. activities. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Related Products of 1985-51-9

The Article related to monomer phospholipid liposome interaction, vinyl monomer phospholipid liposome interaction, acrylate phospholipid liposome interaction, methacrylate phospholipid liposome interaction, dental monomer interaction liposome and other aspects.Related Products of 1985-51-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 5, 1992, Sugitani, Hatsuo; Fukasawa, Masato; Katou, Kouichi published an article.Electric Literature of 1985-51-9 The title of the article was Analysis of poly-functional acrylates and methacrylates by reversed-phase liquid chromatography with photodiode-array detector. And the article contained the following:

Identification and quant. determination of crosslinking agents in photosensitive materials were studied by reversed-phase liquid chromatog. using a photodiode-array detector. Thirty-two kinds of polyfunctional acrylates and methacrylates (crosslinking agents) were studied. As a result of this study, 30 kinds of the polyfunctional (meth)acrylates were successfully identified and determined by the gradient elution method using MeCN-H2O as the eluent. This method provided good reproducibilities in the elution volumes (0.20∼3.09%) and peak areas (0.34∼0.32%) in each sample. This method was applied to the anal. of crosslinking agents in com. available solid-type and liquid-type photosensitive materials and proved to be a rapid and very accurate method. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Electric Literature of 1985-51-9

The Article related to reverse phase hplc crosslinking agent determination, photosensitive composition hardener determination hplc, acrylate crosslinking agent determination hplc, methacrylate crosslinking agent determination hplc, liquid chromatog acrylate crosslinking agent determination and other aspects.Electric Literature of 1985-51-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cermak, Vladimir; Trnecka, Vladimir published an article in 1980, the title of the article was Photopolymer compounds with a higher degree of flexibility. II. Compounds based upon epoxyacrylates.Quality Control of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate) And the article contains the following content:

All cured epoxy-acrylate compositions based on epoxy resin ChS 15 [25068-38-6] and various acrylates had a higher flexibility and lower hardness than epoxy-methacrylate compositions Of the several acrylate monomers studied, only 2-ethylhexyl acrylate (I) [103-11-7] at concentration >20% exhibited a plasticizing influence. The composition having the best mech. properties and a high curing rate contained 10% I and 20% trimethylolpropane triacrylate [15625-89-5]. Diacrylates did not significantly affect the mech. properties. of the compositions but favorably influenced their viscosity. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Quality Control of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

The Article related to epoxy acrylate composition flexibility hardness, methacrylate epoxy composition flexibility hardness, ethylhexyl acrylate epoxy composition, flexibility epoxy acrylate photopolymerized composition, trimethylolpropane triacrylate photopolymerization composition, photopolymerization composition epoxy acrylate and other aspects.Quality Control of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics