Category: 19788-49-9

Liu, Gang published the artcileBenzofused tricycles based on 2-quinoxalinol. [Erratum to document cited in CA146:251809], Application In Synthesis of 19788-49-9, the publication is Journal of Combinatorial Chemistry (2008), 10(2), 343, database is CAplus.

The quinoxalin-2-ol mol. structure published in the article has been recently corrected to be quinoxalin-2-one by X-ray single-crystal anal. of an unambiguous configuration of chem. compound 1, which indicated that it was a 3,4-dihydroquinoxalin-2-one but not a quinoxalin-2-ol. The correct chem. structure for Compound 1 as synthesized by a published standard method is given in supplemental Figure 1.

Journal of Combinatorial Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, Application In Synthesis of 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Liu, Gang published the artcileBenzofused Tricycles Based on 2-Quinoxalinol, Application of Ethyl 2-mercaptopropanoate, the publication is Journal of Combinatorial Chemistry (2007), 9(1), 70-78, database is CAplus and MEDLINE.

This paper describes our recent efforts to synthesize novel compound scaffolds integrating 2-quinoxalinol with privileged structures of 1,3-dihydrobenzoimidazol-2-one, 1,3-dihydrobenzoimidazole-2-thione, 3-hydroxy-1H-quinoxalin-2-one, 2H-benzo[1,4]oxazin-3-ol, 2H-benzo[1,4]thiazin-3-ol, and 1,3,4,5-tetrahydro-benzo[1,4]diazepin-2-one, resp. Eight novel benzofused tricycles and their substituent diversity points were developed. These include pyrazino[2,3-g]quinoxaline-2,8-diol, 3-hydroxy-6,8,9,10-tetrahydro-1,4,6,10-tetraazacyclohepta[b]naphthalen-7-one, 6-hydroxy-4H-1-oxa-4,5,8-triazaanthracen-3-one, 6-hydroxy-4H-1-thia-4,5,8-triazaanthracen-3-one, 6-hydroxy-1,1-dioxo-1,4-dihydro-2H-1λ⁶-thia-4,5,8-triazaanthracen-3-one, 6-hydroxy-1,3-dihydroimidazo[4,5-g]quinoxalin-2-one, 6-hydroxy-1,3-dihydroimidazo[4,5-g]quinoxaline-2-thione, and 7-hydroxy-1,4-dihydropyrazino[2,3-g]quinoxaline-2,3-dione. This strategy of integrating two benzofused privileged structures into one mol. may provide a greater chance for the discovery of novel lead compounds

Journal of Combinatorial Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, Application of Ethyl 2-mercaptopropanoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Bi, Xiaojing published the artcileDCDMH-promoted synthesis of thiophosphates by coupling of H-phosphonates with thiols, Product Details of C5H10O2S, the publication is Tetrahedron (2016), 72(5), 706-711, database is CAplus.

DCDMH-mediated (1,3-dichloro-5,5-dimethylhydantoin) phosphorylation of versatile thiols with H-phosphonates for the preparation of synthetically and biol. important thiophosphates was demonstrated. Without metal catalysts and other additives, phosphorylation occurred to give the desired products with good to excellent yields within 10 min at ambient temperature in the air.

Tetrahedron published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, Product Details of C5H10O2S.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tan, Shaobo published the artcileBase Catalyzed Thiol-Ene Click Chemistry toward Inner -CH=CF- Bonds for Controlled Functionalization of Poly(vinylidene fluoride), HPLC of Formula: 19788-49-9, the publication is Macromolecular Chemistry and Physics (2018), 219(11), n/a, database is CAplus.

A facile and controlled base catalyzed thiol-ene click chem. toward electron-deficient -CH-CF- double bonds in poly(vinylidene fluoride) PVDF (P(VDF-DB)) is reported in present contribution for the first time. The addition reaction is carefully conducted under varied conditions including at the elevated temperature, in the different solvents, and with the altered catalysts and thiols. The addition reaction is well confirmed to follow the base catalyzed route and exhibits close dependence onto the reaction conditions. Besides the addition reaction, the other two side reactions catalyzed by alkylamines, including the further main chain degradation of P(VDF-DB) substrates together with the nucleophilic substitution of thiols to -CH=CF- units, can be completely avoided by choosing a catalyst with a proper pK_a value. With respect to the universality and well controlled feature of the reaction, the low cost and readily prepared P(VDF-DB) substrate and the mild reaction conditions, this strategy may offer a robust tool for attaching various functional groups into PVDF side chain.

Macromolecular Chemistry and Physics published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C8H11BO2, HPLC of Formula: 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Huang, Lily published the artcileIdentification of Potent and Selective Mechanism-Based Inhibitors of the Cysteine Protease Cruzain Using Solid-Phase Parallel Synthesis, Recommanded Product: Ethyl 2-mercaptopropanoate, the publication is Journal of Medicinal Chemistry (2002), 45(3), 676-684, database is CAplus and MEDLINE.

Targeted libraries of ketone-based cysteine protease inhibitors were synthesized and screened against cruzain, a cysteine protease implicated in Chagas’ disease. A number of single digit nanomolar, low mol. weight inhibitors were identified and optimized for solubility and potency. Specifically, the best inhibitors identified have K_i values of 0.9-10 nM and mol. weights between 499 and 609 Da. The most effective inhibitor was also greater than 1000-fold selective for cruzain relative to cathepsin B and 100-fold selective for cruzain relative to cathepsin L.

Journal of Medicinal Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, Recommanded Product: Ethyl 2-mercaptopropanoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Severac, Romain published the artcileReversible addition-fragmentation chain-transfer (RAFT) copolymerization of vinylidene chloride and methyl acrylate, Product Details of C5H10O2S, the publication is Polymer International (2002), 51(10), 1117-1122, database is CAplus.

The reversible addition-fragmentation chain-transfer (RAFT) copolymerization of vinylidene chloride with Me acrylate was investigated at 70°C in benzene. Three benzodithioate chain-transfer agents were synthesized in high yield by a simple and straightforward transesterification method. These dithioesters were successfully used as reversible chain-transfer agents, as demonstrated by the increase of mol. weight with conversion, a relatively low polydispersity index (I_p = 1.5) in comparison with a blank experiment (I_p = 1.9), first-order polymerization kinetics, and efficient chain extension. Nevertheless, a transfer reaction to vinylidene chloride monomer was considered to address the limitations of the RAFT process for this system. Moreover, a retardation effect was noticeable on the kinetics, depending on the structure and concentration of the transfer agent, leading to lower rate of polymerization for lower targeted mol. weights

Polymer International published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C18H34N4O5S, Product Details of C5H10O2S.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Itobe, Takafumi published the artcileNew Factor Characterizing the In-Mouth Release of Odorants (Volatile Thiols): Compositional Changes in Odorants Exhaled from the Human Nose during Drinking, Synthetic Route of 19788-49-9, the publication is Journal of Agricultural and Food Chemistry (2009), 57(23), 11297-11301, database is CAplus and MEDLINE.

The aim of this research was to investigate the relationship between the odorants in the model drink and the odorants reaching the olfactory epithelium using the Retronasal Flavor Impression Screening System (R-FISS). By application of the R-FISS to the odorants in the model drink, it was found that a methylthio ether [1-methoxy-3-methyl-3-(methylthio)butane] was detected with the original volatile thiol (4-methoxy-2-methyl-2-mercaptobutane) in the air exhaled through the nostrils via the nasal cavity after the model drink (including the original thiol) had been swallowed. In addition, this phenomenon was also observed in other volatile thiols (furfuryl mercaptan, Et 2-mercaptopropionate, 2-methyl-1-mercaptobutane, and 4-mercapto-4-methyl-2-pentanone). These compositional changes in thiols that were observed in the air exhaled through the nostrils could be affected by the chem. structure of each tested thiol and individual differences. These results pointed to a possibility that the odorants reaching the olfactory receptor via the throat during consumption of foods could not always retain their original chem. structures and compositions in foodstuffs. Therefore, the characteristic odor of volatile thiols might be perceived due to the stimuli of multiple compounds To understand in detail flavor perception during the consumption of foods, not only the compositions or amounts of odorants in foodstuffs but also the compositional changes in odorants induced by biol. reactions (reduction or methylation) need to be taken into consideration.

Journal of Agricultural and Food Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, Synthetic Route of 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Meng, Qi published the artcileContribution of 2-methyl-3-furanthiol to the cooked meat-like aroma of fermented soy sauce, Safety of Ethyl 2-mercaptopropanoate, the publication is Bioscience, Biotechnology, and Biochemistry (2017), 81(1), 168-172, database is CAplus and MEDLINE.

The cooked meat-like aroma compound, 2-methyl-3-furanthiol (2M3F), was detected in fermented soy sauce (FSS) by GC-olfactometry and GC-MS. 2M3F was present in FSS at a concentration considerably greater than the perception threshold, and the 2M3F concentration increased with heating temperature Sensory anal. indicated that with the addition of only 0.2 μg/L of 2M3F to the soy sauce sample, the cooked meat-like aroma is significantly stronger than that of sample without the addition of 2M3F. Hence, 2M3F contributes to the cooked meat-like aroma of FSS, which constitutes the key aroma component of FSS. In addition, 2M3F was generated from the addition of ribose and cysteine in FSS by heating at 120 °C, but it was not detected in a phosphate buffer under the same condition. Furthermore, 2M3F was not detected in acid-hydrolyzed vegetable-protein-mixed soy sauce (ASS) and heated ASS. These results indicated that fermentation by micro-organisms facilitates the generation of 2M3F in FSS.

Bioscience, Biotechnology, and Biochemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, Safety of Ethyl 2-mercaptopropanoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hero, Devid published the artcileFree- and reversible deactivation radical (co)polymerization of isobutylene in water under environmentally benign conditions, COA of Formula: C5H10O2S, the publication is European Polymer Journal (2021), 110336, database is CAplus.

The synthesis of a linear polyisobutylene is achieved for the first time by free radical polymerization The reaction was performed in environmentally friendly conditions, i.e., in an aqueous medium using cyclodextrin solubilizer, around room temperature This mild and straightforward radical polymerization resulted in a predominantly linear polymer with low dispersity. Isobutylene was also copolymerized with acrylamide via this cyclodextrin assisted aqueous free-radical polymerization, leading to new poly(isobutylene-co-acrylamide) amphiphilic copolymers. The feed composition of copolymerization had a huge effect on the composition and, therefore, the resulting copolymers solubility Reversible addition-fragmentation chain transfer radical polymerization (RAFT) of isobutylene was also carried out using a PEG-based sym. macro chain transfer agent. Poly(PEG-b-isobutylene-b-PEG) block-copolymer was formed in this one-pot reaction. This novel polymerization method for isobutylene opens new, environmentally benign routes to produce novel copolymers for various applications.

European Polymer Journal published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, COA of Formula: C5H10O2S.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Shejul, Pravin B. published the artcileSynthesis of (Z)-2-alkylidene-4-oxo-thiazolidine derivatives under microwave irradiation, Recommanded Product: Ethyl 2-mercaptopropanoate, the publication is Asian Journal of Chemistry (2008), 20(7), 5427-5433, database is CAplus.

In comparison to conventional technique, exptl. evidence reveals the benefits of the microwave-promoted synthesis of functionalized 4-oxo-thiazolidine derivatives in terms of simple workup, efficiency and safe reproducibility.

Asian Journal of Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C20H12N2O2, Recommanded Product: Ethyl 2-mercaptopropanoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics