Category: 19788-49-9

Li, Jiajia published the artcilePhotoinduced controlled radical polymerization of methyl acrylate and vinyl acetate by xanthate, Quality Control of 19788-49-9, the publication is Polymer Chemistry (2018), 9(21), 2897-2904, database is CAplus.

A novel fluoro-xanthate, 2-((4-fluorophenoxycarbonothioyl)thio)ethyl propanoate, was developed and successfully used as a mediator in the photoinduced controlled radical polymerization of more-activated monomers (Me acrylate (MA), Bu acrylate, and N-isopropylacrylamide) and a less-activated monomer (vinyl acetate (VAc)). The controlled characteristics of the polymerization were demonstrated by the linearly increasing molar mass with conversion, producing polymers with narrow molar mass distributions (1.14-1.37) for MA and VAc. Furthermore, the block copolymer of PMA-b-PVAc was successfully synthesized through chain-extension using PMA as the macro-RAFT agent and VAc as the second monomer.

Polymer Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, Quality Control of 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Naumov, Pance published the artcileStructure and Spectroscopy of Oxyluciferin, the Light Emitter of the Firefly Bioluminescence, Application In Synthesis of 19788-49-9, the publication is Journal of the American Chemical Society (2009), 131(32), 11590-11605, database is CAplus and MEDLINE.

The crystal structures of the pure, unsubstituted firefly emitter oxyluciferin (OxyLH₂) and its 5-Me analog (MOxyLH₂) were determined for the first time to reveal that both mols. exist as pure trans-enol forms, enol-OxyLH₂ and enol-MOxyLH₂, assembled as head-to-tail hydrogen-bonded dimers. Their steady-state absorption and emission spectra (in solution and in the solid state) and nanosecond time-resolved fluorescence decays (in solution) were recorded and assigned to the six possible trans chem. forms of the emitter and its anions. The spectra of the pure emitter were compared to its bioluminescence and fluorescence spectra when it is complexed with luciferase from the Japanese firefly (Luciola cruciata) and interpreted in terms of the intermol. interactions based on the structure of the emitter in the luciferase active site. The wavelengths of the emission spectral maxima of the six chem. forms of OxyLH₂ are generally in good agreement with the theor. predicted energies of the S-S₁ transitions and range from the blue to the red regions, while the resp. absorption maxima range from the UV to the green regions. It was confirmed that both neutral forms, phenol-enol and phenol-keto, are blue emitters, whereas the phenolate-enol form is yellow-green emitter. The phenol-enolate form, which probably only exists as a mixture with other species, and the phenolate-enolate dianion are yellow or orange emitters with close position of their emission bands. The phenolate-keto form always emits in the red region. The concentration ratio of the different chem. species in solutions of OxyLH₂ is determined by several factors which affect the intricate triple chem. equilibrium, most notably the pH, solvent polarity, hydrogen bonding, presence of addnl. ions, and π-π stacking. Due to the stabilization of the enol group of the 4-hydroxythiazole ring by hydrogen bonding to the proximate adenosine monophosphate, which according to the d. functional calculations is similar to that due to the dimerization of two enol mols. observed in the crystal, the phenolate ion of the enol tautomer, which is the predominant ground-state species within the narrow pH interval 7.44-8.14 in buffered aqueous solutions, is the most probable emitter of the yellow-green bioluminescence common for most wild-type luciferases. This conclusion is supported by the bioluminescence/fluorescence spectra and the NMR data, as well the crystal structures of OxyLH₂ and MOxyLH₂, where the conjugated acid (phenol) of the emitter exists as pure enol tautomer.

Journal of the American Chemical Society published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, Application In Synthesis of 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Katritzky, Alan R. published the artcileNovel Syntheses of 2,3-Dihydro-1,5-benzothiazepin-4(5H)-ones and 2H-1,4-Benzothiazin-3(4H)-ones, SDS of cas: 19788-49-9, the publication is Journal of Organic Chemistry (2001), 66(20), 6792-6796, database is CAplus and MEDLINE.

Nucleophilic additions of α-mercaptoalkanoate esters and β-mercaptoalkanoate acids to benzoquinone diimines, followed by cyclization with trifluoroacetic acid or 1,3-dicyclohexylcarbodiimide (DCC), provide novel, high-yielding syntheses of 2H-1,4-benzothiazin-3(4H)-ones and 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones, resp.

Journal of Organic Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, SDS of cas: 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zapol’skii, Viktor A. published the artcileChemistry of polyhalogenated nitrobutadienes, 14: efficient synthesis of functionalized (Z)-2-allylidenethiazolidin-4-ones, Name: Ethyl 2-mercaptopropanoate, the publication is Beilstein Journal of Organic Chemistry (2014), 1638-1644, 7 pp., database is CAplus and MEDLINE.

The reaction of mercaptoacetic acid esters with pentachloro-2-nitro-1,3-butadiene provides an appropriate precursor for the synthesis of special thiazolidin-4-ones. Applying different anilines as the second constituent for the requisite cyclization step, a series of (Z)-2-allylidenethiazolidin-4-ones I (Ar = 4-ClC₆H₄, 4-MeOC₆H₄, 4-MeC₆H₄) was obtained in yields up to 81%. Some subsequent reactions have been examined too, such as the formation of perfunctionalized 1H-pyrazoles upon treatment with hydrazine. Thiazolidinones are as well known for their physiol. activities as for their application in optoelectronics.

Beilstein Journal of Organic Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C16H29BO2, Name: Ethyl 2-mercaptopropanoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Teng, Shuang published the artcileTogni-II Reagent Mediated Selective Hydrotrifluoromethylation and Hydrothiolation of Alkenes, Category: esters-buliding-blocks, the publication is Chinese Journal of Chemistry (2021), 39(12), 3429-3434, database is CAplus.

Based on the redox reactions of Togni-II reagent and thiols (such as propane-2-thiol, cyclohexanethiol, dodecan-1-thiol, p-toluenethiol, etc.), a thiol-tuned selective functionalization of unactivated olefins was disclosed. In combination with aryl thiol (p-toluenethiol), stoichiometric amount of Togni-II reagent prompted a hydrotrifluoromethylation of alkenes (such as N-allyl-benzamide, 1-phenyl-but-3-en-1-ol, 4-chloro-benzoic acid pent-4-enyl ester, etc.), in which, aryl thiol played as reductant and hydrogen source; while by utilization of alkyl thiols (such as propane-2-thiol, cyclohexanethiol, dodecan-1-thiol, etc.), catalytic amount of Togni-II reagent initiated thiol-ene and thiol-yne reactions. The reported applications are characterized by their operational simplicity and wide functional group tolerance.

Chinese Journal of Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C14H19NO8, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Marchand, Patrice published the artcileSynthesis and characterization of diaminodithio- and aminotrithiophosphoric acid esters, HPLC of Formula: 19788-49-9, the publication is Phosphorus, Sulfur and Silicon and the Related Elements (2007), 182(6), 1233-1244, database is CAplus.

The synthesis and characterization of a series of five new diaminodithiophosphoric acid esters (R¹R²N)₂P(S)SR and five new aminotrithiophosphoric acid esters (R¹R²N)P(S)(SR)₂ are described. The structure of two of these compounds, the diaminodithio derivative (iPr₂N)₂P(S)SCH₂Ph and the aminotrithio derivative (iPr₂N)P(S)(SCH₂Ph)₂, has been determined by single crystal X-ray diffraction. These series of compounds are potentially usable as agents for reversible addition-fragmentation chain transfer polymerization

Phosphorus, Sulfur and Silicon and the Related Elements published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, HPLC of Formula: 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Boyle, Sean Michael published the artcileExpanding the olfactory code by in silico decoding of odor-receptor chemical space, Recommanded Product: Ethyl 2-mercaptopropanoate, the publication is eLife (2013), e01120/1-e01120/17, 17 pp., database is CAplus and MEDLINE.

Coding of information in the peripheral olfactory system depends on two fundamental factors: interaction of individual odors with subsets of the odorant receptor repertoire and mode of signaling that an individual receptor-odor interaction elicits, activation or inhibition. We develop a cheminformatics pipeline that predicts receptor-odorant interactions from a large collection of chem. structures (>240,000) for receptors that have been tested to a smaller panel of odorants (∼100). Using a computational approach, we first identify shared structural features from known ligands of individual receptors. We then use these features to screen in silico new candidate ligands from >240,000 potential volatiles for several Odorant receptors (Ors) in the Drosophila antenna. Functional experiments from 9 Ors support a high success rate (∼71%) for the screen, resulting in identification of numerous new activators and inhibitors. Such computational prediction of receptor-odor interactions has the potential to enable systems level anal. of olfactory receptor repertoires in organisms.

eLife published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, Recommanded Product: Ethyl 2-mercaptopropanoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Abel, Brooks A. published the artcile“One-Pot” Aminolysis/Thiol-Maleimide End-Group Functionalization of RAFT Polymers: Identifying and Preventing Michael Addition Side Reactions, Product Details of C5H10O2S, the publication is Macromolecules (Washington, DC, United States) (2016), 49(17), 6193-6202, database is CAplus.

We show that many of the nucleophiles (catalysts, reducing agents, amines, thiols) present during “one-pot” aminolysis/thiol-maleimide end-group functionalization of RAFT polymers can promote side reactions that substantially reduce polymer end-group functionalization efficiencies. The nucleophilic catalyst 1,8-diazabicyclo[5.4.0]undec-7-ene and the reducing agent tributylphosphine were shown to initiate anionic polymerization of N-methylmaleimide (NMM) in both polar and nonpolar solvents whereas hexylamine-initiated polymerization of NMM occurred only in high-polarity solvents. Furthermore, triethylamine-catalyzed Michael reactions of the representative thiol Et 2-mercaptopropionate (E2MP) and NMM in polar solvents resulted in anionic maleimide polymerization when [NMM]₀ > [E2MP]₀. Base-catalyzed enolate formation on the α-carbon of thiol-maleimide adducts was also shown as an alternative initiation pathway for maleimide polymerization in polar solvents. Ultimately, optimal “one-pot” reaction conditions were identified allowing for up to 99% maleimide end-group functionalization of dithiobenzoate-terminated poly(N,N-dimethylacrylamide). Much of the work described herein can also be used to ensure near-quant. conversion of small mol. thiol-maleimide reactions while preventing previously unforeseen side reactions.

Macromolecules (Washington, DC, United States) published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, Product Details of C5H10O2S.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tandon, Vishnu K. published the artcileNaphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: Synthesis and biological evaluation as potential antibacterial and antifungal agents, SDS of cas: 19788-49-9, the publication is Bioorganic & Medicinal Chemistry Letters (2006), 16(22), 5883-5887, database is CAplus and MEDLINE.

A series of 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thio-alkanoate derivatives and naphtho[2,3-b][1,4]-thiazine-5,10-diones, e.g. I, were synthesized and evaluated for their antibacterial and antifungal activities. The structure-activity relationships of these compounds were studied and the results show that I exhibited better antibacterial activity than Gentamycin in vitro against Staphylococcus aureus. In addition I also imparted marked antifungal activity in vitro against Cryptococcus neoformans, Sporothrix schenckii, and Trichophyton mentagrophytes when compared with Fluconazole. Some other compounds also exhibited significant antibacterial activity in vitro against S. aureus.

Bioorganic & Medicinal Chemistry Letters published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C4H6N2, SDS of cas: 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tandon, Vishnu K. published the artcile“On water” assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents, Recommanded Product: Ethyl 2-mercaptopropanoate, the publication is European Journal of Medicinal Chemistry (2010), 45(6), 2418-2426, database is CAplus and MEDLINE.

2-Chloro-3-(4-methylpiperazin-1-yl)naphthalene-1,4-dione, 2-chloro-3-(pyrrolidin-1-yl)naphthalene-1,4-dione, 2-chloro-3-(piperidin-1-yl)naphthalene-1,4-dione, 2-chloro-3-morpholinonaphthalene-1,4-dione, 2-chloro-3-(2-phenylhydrazinyl)naphthalene-1,4-dione, 2-(allylamino)-3-chloronaphthalene-1,4-dione, 2-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-ylthio)acetic acid, 2-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-ylthio)succinic acid, Me 2-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-ylthio)acetate, 2-chloro-3-(2-mercaptoethylthio)naphthalene-1,4-dione (I), 3-hydroxy-4-methyl-4H-naphtho[2,3-b][1,4]thiazine-5,10-dione, etc, have been synthesized by a green methodol. approach using water as solvent and evaluated for their antifungal and antibacterial activities. Several compounds, e.g., I, were found to have better antifungal activity than clin. prevalent antifungal drugs Fluconazole and Amphotericin-B against Trichophyton mentagrophytes and compounds

European Journal of Medicinal Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H11NO2S, Recommanded Product: Ethyl 2-mercaptopropanoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics