1190-39-2 Archives - Page 2 of 2 - Esters-buliding-blocks

Huang, Zhusheng et al. published their research in Organic Chemistry Frontiers in 2017 | CAS: 1190-39-2

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Related Products of 1190-39-2

Phosphine-mediated domino reactions of phthalimidomalonates with allenoates or but-2-ynoate: facile entry into highly functionalized pyrroloisoindolinone derivatives was written by Huang, Zhusheng;Chen, Qingqing;Yang, Xiuqin;Liu, Yang;Zhang, Li;Lu, Tao;Zhou, Qingfa. And the article was included in Organic Chemistry Frontiers in 2017.Related Products of 1190-39-2 This article mentions the following:

A phosphine-mediated domino reaction between phthalimidomalonates and allenoates furnishes highly functionalized pyrroloisoindolinone derivatives, e.g., I, in synthetically useful yields. When Et but-2-ynoate was reacted with phthalimidomalonates under the same conditions, pyrroloisoindolinone derivatives were also obtained in good to excellent yields. The mechanism for the transformation is a tandem γ-umpolung/Wittig/γ-umpolung process. The present domino reaction not only exploits the potential of allenoates, but also extends the existing phosphine-mediated cyclization scope. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Related Products of 1190-39-2).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zou, Wenwu et al. published their research in Youji Huaxue in 2013 | CAS: 1190-39-2

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks

Synthesis of new donor-acceptor copolymer and its application in organic bulk hetero-junction solar cells was written by Zou, Wenwu;Liu, Ying;Jia, Qingming;Ge, Ziyi. And the article was included in Youji Huaxue in 2013.Category: esters-buliding-blocks This article mentions the following:

Alternative copolymer (PBDTDT) was synthesized from acceptor unit with strong electro-withdrawing structure of di-Bu malonate in branch chain and donor unit based on benzo[1,2-b:4,5-b’]dithiophene. And its thermal, optical, electrochem. properties and photovoltaic properties blending with [6,6]-phenyl-C₇₁ butyric acid Me ester as the active layer in the bulk hetero-junction devices of organic solar cells were investigated. The influence of different ratio of polymer PBDTDT and PC₇₁BM on the photovoltaic properties was also studied. And the open voltage reached 0.82 V, when the weight ratio of PBDTDT and PC₇₁BM is 1 3, and its power conversion efficiency (PCE) was 0.90%, with V_oc of 0.82 V, J_sc of 3.25 mA/cm² and FF of 33.8%. Comparing with the poly(3-hexylthiophene) (P3HT) in the same method, the solar cells with P3HT blending with PC₇₁BM as the active layer can only get 0.55 V, which can be lower about 0.29 V than that of the PBDTDT. And the possible factors resulting in low PCE and the higher open voltage than that of P3HT were analyzed. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Category: esters-buliding-blocks).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Santilli, Arthur A. et al. published their research in Journal of Medicinal Chemistry in 1987 | CAS: 1190-39-2

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Category: esters-buliding-blocks

2-Oxo-1,8-naphthyridine-3-carboxylic acid derivatives with potent gastric antisecretory properties was written by Santilli, Arthur A.;Scotese, Anthony C.;Bauer, Raymond F.;Bell, Stanley C.. And the article was included in Journal of Medicinal Chemistry in 1987.Category: esters-buliding-blocks This article mentions the following:

The syntheses of 2-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, e.g., I (R = H, Me, Et, Pr, allyl, etc.; R¹ = NH₂, 4-methylpiperazinyl, etc.; R² = H, Me), having potent gastric antisecretory properties in the Shay rat model are described. Two of the more potent compounds tested that were selected for more detailed dose-response evaluation were I (R = Et, R¹ = NH₂, R² = H; II) and I (R = Et, R¹ = 4-methylpiperazinyl, R² = Me; III). II and III lowered total acid output in a dose-related fashion, were more potent than cimetidine, and showed inhibitory activity in food-stimulated acid secretion in the Pavlov dog. The mechanism of action for this series is not known. Details of structure-activity relationships are described. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Category: esters-buliding-blocks).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The important role of 1190-39-2

At the same time, in my other blogs, there are other synthetic methods of this type of compound, malonic acid dibutyl ester, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 1190-39-2, name is malonic acid dibutyl ester, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1190-39-2, Formula: C11H20O4

General procedure: According to the literature procedure,10e a 250 mL, two-necked, round-bottomed flask was charged with diethyl malonate (40.0 mmol), water (40.0 mmol), and ethanol (45 mL), the mixture was stirred in 40 C oil bath for 2 h. After that, a solution of potassium tert-butoxide (40.0 mmol) in ethanol (45 mL) was added slowly over 30 min. After completion of addition, the reaction mixture was stirred in 40 C oil bath until consumption of the starting material (monitored by GC analysis). After removing the ethanol solvent by slow evaporation on rotary evaporator, 20 ml diethyl ether was added. The resulting solid was collected by filtration, washed sequentially with 1:1 mixture of diethyl ether and ethanol (5 mL×2) and diethyl ether (10 mL×3), transferred to a round-bottomed flask and dried under vacuum at 50 C for 10 h to provide ethyl potassium malonate in 85% yield.

At the same time, in my other blogs, there are other synthetic methods of this type of compound, malonic acid dibutyl ester, and friends who are interested can also refer to it.

Reference:
Article; Feng, Yi-Si; Wu, Wei; Xu, Zhong-Qiu; Li, Yan; Li, Ming; Xu, Hua-Jian; Tetrahedron; vol. 68; 9; (2012); p. 2113 – 2120;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

New learning discoveries about 1190-39-2

The synthetic route of 1190-39-2 has been constantly updated, and we look forward to future research findings.

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1190-39-2, name is malonic acid dibutyl ester belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C11H20O4

Exemplary Synthesis 8 Method of Synthesis of Exemplary Compound 8 (0232) (0233) Intermediate 3 (16 g), dibutylmalonate (17 g), triethylamine (7.9 g) and acetonitrile (60 ml) were placed in a flask, and the content was stirred at 100 C. for 4 hours. Acetonitrile was removed, the residue was purified by column chromatography, and the eluate was recrystallized from ethanol to obtain a target product. The crystal was dried at 50 C. under air flow, to obtain 3.2 g of Exemplary Compound 8. (0234) lambdamax=370 nm (AcOEt) (0235) 1H-NMR (CDCl3) delta: 7.95 (d, 1H), 5.31 (d, 1H), 4.07 (s, 2H), 4.22 (s, 4H), 2.74 (s, 3H), 1.62-1.35 (m, 8H), 1.27 (s, 6H), 1.02 to 0.83 (m, 6H)

The synthetic route of 1190-39-2 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; FUJIFILM CORPORATION; NORIZUKI, Yutaro; WATANABE, Yukie; TAKAHASHI, Kazutaka; (21 pag.)US2016/16919; (2016); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Introduction of a new synthetic route about 1190-39-2

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1190-39-2.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1190-39-2, name is malonic acid dibutyl ester, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: malonic acid dibutyl ester

EXAMPLE 4 Example 3 was repeated except the organic solvent was omitted and the mol ratio of trans 1,4-dichlorobutene-2 to di-n-butyl malonate was 2:1. Di-n-butyl 2-vinylcyclopropane-1,1-dicarboxylate was obtained in 69% yield.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1190-39-2.

Reference:
Patent; Emery Industries, Inc.; US4252739; (1981); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The important role of 1190-39-2

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of malonic acid dibutyl ester.

Adding some certain compound to certain chemical reactions, such as: 1190-39-2, name is malonic acid dibutyl ester, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1190-39-2. 1190-39-2

General procedure: PhIO (550 mg, 2.5 mmol), Et3N¡¤5HF (800 mg, 4 mmol), and DCE (1 mL)were placed in a Teflon test tube. After stirring at r.t. for 15 min, the appropriate malonic ester 1 (1 mmol) and DCE (1 mL) were added. The test tube was sealed with a septum rubber and heated at 70 C for 24 h with stirring. The reaction mixture was neutralized with aq NaHCO3 and the product was extracted with CH2Cl2 (3 ¡Á 10 mL). The combined organic layers were washed with brine (20 mL), dried (Na2SO4), and concentrated under reduced pressure. The product was purified by column chromatography on silica gel with hexane-CH2Cl2 as eluent.

Reference:
Article; Kitamura, Tsugio; Muta, Kensuke; Oyamada, Juzo; Synthesis; vol. 47; 20; (2015); p. 3241 – 3245;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics