Category: 119-36-8

Cheng, Chi-Yuan; Brinzari, Tatiana V.; Hao, Zhigang; Wang, Xiaotai; Pan, Long published an article in 2021. The article was titled 《Understanding Methyl Salicylate Hydrolysis in the Presence of Amino Acids》, and you may find the article in Journal of Agricultural and Food Chemistry.SDS of cas: 119-36-8 The information in the text is summarized as follows:

Me salicylate, the major flavor component in wintergreen oil, is commonly used as food additives. It was found that amino acids can unexpectedly expedite Me salicylate hydrolysis in an alk. environment, while the detailed mechanism of this reaction merits investigation. Herein, the role of amino acid, more specifically, glycine, in Me salicylate hydrolysis in aqueous solution was explored. 1H NMR spectroscopy, combined with d. functional theory calculations, was employed to investigate the Me salicylate hydrolysis in the presence and absence of glycine at pH 9. The addition of glycine was found to accelerate the hydrolysis by an order of magnitude at pH 9, compared to that at pH 7. The end hydrolyzed product was confirmed to be salicylic acid, suggesting that glycine does not directly form an amide bond with Me salicylate via aminolysis. Importantly, our results indicate that the ortho-hydroxyl substituent in Me salicylate is essential for its hydrolysis due to an intramol. hydrogen bond, and the carboxyl group of glycine is crucial to Me salicylate hydrolysis. This study gains a new understanding of Me salicylate hydrolysis that will be helpful in finding ways of stabilizing wintergreen oil as a flavorant in consumer food products that also contain amino acids. The experimental part of the paper was very detailed, including the reaction process of Methyl Salicylate(cas: 119-36-8SDS of cas: 119-36-8)

Methyl Salicylate(cas: 119-36-8) has been used: as a component of clarifying solution for treating Mongolian gerbil cochlea intact for immunofluorescence analysis, as a plant elicitor to test its effect on reducing the whitefly population from tomato plants.SDS of cas: 119-36-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Seed treatment and foliar application of methyl salicylate (MeSA) as a defense mechanism in rice plants against the pathogenic bacterium, Xanthomonas oryzae pv. oryzae》 was written by Kalaivani, Kandasamy; Maruthi-Kalaiselvi, Marimuthu; Senthil-Nathan, Sengottayan. Quality Control of Methyl SalicylateThis research focused onXanthomonas oryzae methyl salicylate seed treatment foliar application; Blight; Induced defense; PR-protein; Plant-hormone; Rice. The article conveys some information:

Me salicylate (MeSA) is a volatile biol. compound synthesized from salicylic acid (SA) and is a plant hormone that helps defend against pests and pathogens. A major bacterial pathogen of rice, Xanthomonas oryzae pv. oryzae (Xoo) causes severe disease. Seed and plant treatments with MeSA can stimulate the defense enzyme peroxidase (POD) in plants. Response of peroxidase activity in rice (Oryza sativa L) cultivars IR 20, IR 50, IR 64, ASD 16, ASD 19 and ADT 46 to MeSA were measured under greenhouse conditions. Treatments of rice seedlings with MeSA at 50 and 100 mg L-1 significantly upregulated POD expression in the plants. The activity of POD was also significantly upregulated when plants were inoculated with bacterial blight. Effects were stronger in ASD 16, ASD 19 and ADT 46 and were more pronounced in high dose treatment (100 mg L-1) when inoculated with bacterial blight condition and the effects were dose dependent, although the relationship between dose and rice varieties were not always linear. The pathogenic related (PR) protein bands at 33 kDa and 14 kDa were identified in treatments of 100 mg L-1 MeSA in the presence of bacterial blight disease. Band intensity was estimated to be twice that of those from pathogen induce MeSA levels in rice plants. These results suggest that treatment with MeSA can significantly increase the POD defense related enzyme by altering the plant physiol. in ways that may be beneficial for crop protection. The results came from multiple reactions, including the reaction of Methyl Salicylate(cas: 119-36-8Quality Control of Methyl Salicylate)

Methyl Salicylate(cas: 119-36-8) is a natural herbivore-induced plant volatile. It is a naturally occurring product in trees, legumes, exotic plants, vegetables, berries, and the primary constituent of the oil of wintergreen.Methyl Salicylate is produced from salicylic acid.Quality Control of Methyl Salicylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Green synthesis of methyl salicylate using novel sulfated iron oxide-zirconia catalyst》 were Molleti, Jayaram; Yadav, Ganapati D.. And the article was published in Clean Technologies and Environmental Policy in 2019. Product Details of 119-36-8 The author mentioned the following in the article:

Esters of salicylic acid are in demand for the synthesis of drugs, food preservatives, pharmaceuticals, perfumes and solvents. A novel sulfated Fe2O3-ZrO2 catalyst with different iron loadings was prepared by the combustion technique and used in the preparation of Me salicylate from salicylic acid and di-Me carbonate. This process is a viable and safe substitute to other esterification processes, involving harmful alkylating agents and chems. The activity of sulfated Fe2O3-ZrO2 was evaluated for the esterification of salicylic acid with di-Me carbonate. No solvent was used and hence the quality of the product was excellent. The product Me salicylate is extensively used in the food and pharma industries. Catalysts with different loadings of iron on zirconia (5, 10, 15, 20 weight%) were synthesized, and their activities evaluated vis-a-́vis ZrO2 and sulfated zirconia. The catalysts were characterized using SEM, XRD, FTIR, TGA, NH3-TPD and BET surface area anal. The activity of the catalysts increases after the loading of iron on zirconia and 10 weight% sulfated Fe2O3-ZrO2 gave the highest acidity and activity for the synthesis of Me salicylate. The effect of various kinetic parameters on the rate of esterification of salicylic acid was studied. The optimum conditions for 99% conversion of salicylic acid with 100% selectivity was 120 °C after 150 min at a 1:10 molar ratio of salicylic acid to di-Me carbonate and catalyst loading of 0.03 g/cm3. The reaction mechanism and kinetics were studied. The activation energy for this reaction was found to be 13.82 kcal/mol.Methyl Salicylate(cas: 119-36-8Product Details of 119-36-8) was used in this study.

Methyl Salicylate(cas: 119-36-8) is a natural herbivore-induced plant volatile. It is a naturally occurring product in trees, legumes, exotic plants, vegetables, berries, and the primary constituent of the oil of wintergreen.Methyl Salicylate is produced from salicylic acid.Product Details of 119-36-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Virgen, Camila A.; Fox, James D.; Santariello, Peter; Winfield, Jaime L.; Wright, Kenneth C.; Verbeck, Guido F. published an article in 2021. The article was titled 《Portable membrane inlet mass spectrometric detection and analysis of chemical warfare agent simulants at the U.S. Army Dugway Proving Ground S/K challenge event》, and you may find the article in International Journal of Mass Spectrometry.Product Details of 119-36-8 The information in the text is summarized as follows:

There has been a significant demand for the development and improvement of technol. used for the detection and identification of Chem. Warfare Agents (CWAs). Some of the current detection technol. being used by the U. S. government includes multipass gas cell coupled Fourier Transform IR (FTIR) spectroscopy and Lightweight Chem. Detectors (LCD) systems. While these systems possess adequate sensitivity to detect CWAs in general, their anal. times are not considered rapid nor are they able to identify the specific CWA. The U. S. Army Dugway Proving Grounds annual S/K Challenge event provides the opportunity to assess the performance and reliability of prospective detection instrumentation being developed by researchers worldwide to optimize their performance. To do so, trial testing of CWA simulants in both indoor and outdoor environments was performed, mimicking past attack scenarios. Membrane Inlet Mass Spectrometric (MIMS) technol. on a portable system was successful in performing a rapid anal. along with identification of each CWA simulant utilized during the trials. The MIMS system can detect and quantify low-mass permeable compounds with parts-per-trillion limits of detection. This allows for anal. to be achieved within seconds after the initial exposure time, which is significantly faster than the FTIR and LCD systems currently used. In the experimental materials used by the author, we found Methyl Salicylate(cas: 119-36-8Product Details of 119-36-8)

Methyl Salicylate(cas: 119-36-8) is a natural herbivore-induced plant volatile. It is a naturally occurring product in trees, legumes, exotic plants, vegetables, berries, and the primary constituent of the oil of wintergreen.Methyl Salicylate is produced from salicylic acid.Product Details of 119-36-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Green synthesis of methyl salicylate using novel sulfated iron oxide-zirconia catalyst》 were Molleti, Jayaram; Yadav, Ganapati D.. And the article was published in Clean Technologies and Environmental Policy in 2019. Product Details of 119-36-8 The author mentioned the following in the article:

Esters of salicylic acid are in demand for the synthesis of drugs, food preservatives, pharmaceuticals, perfumes and solvents. A novel sulfated Fe2O3-ZrO2 catalyst with different iron loadings was prepared by the combustion technique and used in the preparation of Me salicylate from salicylic acid and di-Me carbonate. This process is a viable and safe substitute to other esterification processes, involving harmful alkylating agents and chems. The activity of sulfated Fe2O3-ZrO2 was evaluated for the esterification of salicylic acid with di-Me carbonate. No solvent was used and hence the quality of the product was excellent. The product Me salicylate is extensively used in the food and pharma industries. Catalysts with different loadings of iron on zirconia (5, 10, 15, 20 weight%) were synthesized, and their activities evaluated vis-a-́vis ZrO2 and sulfated zirconia. The catalysts were characterized using SEM, XRD, FTIR, TGA, NH3-TPD and BET surface area anal. The activity of the catalysts increases after the loading of iron on zirconia and 10 weight% sulfated Fe2O3-ZrO2 gave the highest acidity and activity for the synthesis of Me salicylate. The effect of various kinetic parameters on the rate of esterification of salicylic acid was studied. The optimum conditions for 99% conversion of salicylic acid with 100% selectivity was 120 °C after 150 min at a 1:10 molar ratio of salicylic acid to di-Me carbonate and catalyst loading of 0.03 g/cm3. The reaction mechanism and kinetics were studied. The activation energy for this reaction was found to be 13.82 kcal/mol.Methyl Salicylate(cas: 119-36-8Product Details of 119-36-8) was used in this study.

Methyl Salicylate(cas: 119-36-8) is a natural herbivore-induced plant volatile. It is a naturally occurring product in trees, legumes, exotic plants, vegetables, berries, and the primary constituent of the oil of wintergreen.Methyl Salicylate is produced from salicylic acid.Product Details of 119-36-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Virgen, Camila A.; Fox, James D.; Santariello, Peter; Winfield, Jaime L.; Wright, Kenneth C.; Verbeck, Guido F. published an article in 2021. The article was titled 《Portable membrane inlet mass spectrometric detection and analysis of chemical warfare agent simulants at the U.S. Army Dugway Proving Ground S/K challenge event》, and you may find the article in International Journal of Mass Spectrometry.Product Details of 119-36-8 The information in the text is summarized as follows:

There has been a significant demand for the development and improvement of technol. used for the detection and identification of Chem. Warfare Agents (CWAs). Some of the current detection technol. being used by the U. S. government includes multipass gas cell coupled Fourier Transform IR (FTIR) spectroscopy and Lightweight Chem. Detectors (LCD) systems. While these systems possess adequate sensitivity to detect CWAs in general, their anal. times are not considered rapid nor are they able to identify the specific CWA. The U. S. Army Dugway Proving Grounds annual S/K Challenge event provides the opportunity to assess the performance and reliability of prospective detection instrumentation being developed by researchers worldwide to optimize their performance. To do so, trial testing of CWA simulants in both indoor and outdoor environments was performed, mimicking past attack scenarios. Membrane Inlet Mass Spectrometric (MIMS) technol. on a portable system was successful in performing a rapid anal. along with identification of each CWA simulant utilized during the trials. The MIMS system can detect and quantify low-mass permeable compounds with parts-per-trillion limits of detection. This allows for anal. to be achieved within seconds after the initial exposure time, which is significantly faster than the FTIR and LCD systems currently used. In the experimental materials used by the author, we found Methyl Salicylate(cas: 119-36-8Product Details of 119-36-8)

Methyl Salicylate(cas: 119-36-8) is a natural herbivore-induced plant volatile. It is a naturally occurring product in trees, legumes, exotic plants, vegetables, berries, and the primary constituent of the oil of wintergreen.Methyl Salicylate is produced from salicylic acid.Product Details of 119-36-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

HPLC of Formula: 119-36-8In 2019 ,《Methyl salicylate delays peel yellowing of ‘Zaosu’ pear (Pyrus bretschneideri) during storage by regulating chlorophyll metabolism and maintaining chloroplast ultrastructure》 appeared in Journal of the Science of Food and Agriculture. The author of the article were Zhang, Huaiyu; Wang, Rui; Wang, Tian; Fang, Chunxia; Wang, Junjie. The article conveys some information:

BACKGROUND : In some cultivars, yellowing resulting from chlorophyll breakdown has a direct and neg. effect on food supply and health. The ‘Zaosu’ pear (Pyrus bretschneideri Rehd.), a com. Asian pear cultivar in China, rapidly turns yellow when stored at room temperature after harvest. To develop techniques that delay or suppress chlorophyll degradation, the effects of Me salicylate (MeSA) on yellowing in ‘Zaosu’ pear fruit during storage were evaluated. RESULTS : Compared with the untreated fruit, the application of 0.05 mmol L-1 MeSA delayed the decline of the total chlorophyll, chlorophyll a and chlorophyll b content, and maintained more intact chloroplasts with fewer and smaller plastoglobuli. Me salicylate suppressed enzyme activities, including chlorophyllase, chlorophyll-degrading peroxidase, Mg dechelatase, and pheophytinase, and the expression levels of NYC, NOL, CLH, SGR, PPH, PAO and RCCR in treated fruit. CONCLUSION : Me salicylate could delay chlorophyll breakdown in the fruit. The results also suggested that the conversion from chlorophyll a to pheophorbide a could proceed via two pathways, and that alternative pathways for the breakdown of chlorophyll a exist in ‘Zaosu’ pears. © 2019 Society of Chem. Industry. After reading the article, we found that the author used Methyl Salicylate(cas: 119-36-8HPLC of Formula: 119-36-8)

Methyl Salicylate(cas: 119-36-8) is a natural herbivore-induced plant volatile. It is a naturally occurring product in trees, legumes, exotic plants, vegetables, berries, and the primary constituent of the oil of wintergreen.Methyl Salicylate is produced from salicylic acid.HPLC of Formula: 119-36-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Biosensing with Insect Odorant Receptor Nanodiscs and Carbon Nanotube Field-Effect Transistors》 were Murugathas, Thanihaichelvan; Zheng, Han Yue; Colbert, Damon; Kralicek, Andrew V.; Carraher, Colm; Plank, Natalie O. V.. And the article was published in ACS Applied Materials & Interfaces in 2019. Synthetic Route of C8H8O3 The author mentioned the following in the article:

Insect odorant receptors have been reconstituted into lipid nanodiscs and tethered to carbon nanotube field-effect transistors to function as a biosensor. Here, four different insect odorant receptors (ORs) from Drosophila melanogaster (DmelOR10a, DmelOR22a, DmelOR35a, and DmelOR71a) were expressed in Sf9 cells, purified, and reconstituted into lipid nanodiscs. We have demonstrated that each of these ORs produce a selective and highly sensitive elec. response to their resp. pos. ligands, Me salicylate, Me hexanoate, trans-2-hexen-1-al, and 4-ethylguaiacol, with limits of detection in the low femtomolar range. No detection was observed for each OR against control ligands, and empty nanodiscs showed no specific sensor signal for any of the odorant mols. Our results are the first evidence that insect ORs can be integrated into lipid nanodiscs and used as primary sensing elements for bioelectronic nose technologies. In the experiment, the researchers used Methyl Salicylate(cas: 119-36-8Synthetic Route of C8H8O3)

Methyl Salicylate(cas: 119-36-8) has been used: as a component of clarifying solution for treating Mongolian gerbil cochlea intact for immunofluorescence analysis, as a plant elicitor to test its effect on reducing the whitefly population from tomato plants.Synthetic Route of C8H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2022,Xu, Pingxi; Choo, Young-Moo; Leal, Walter S. published an article in Biochemical and Biophysical Research Communications. The title of the article was 《Odorant inhibition in mosquito olfaction mediated by inverse agonists》.Category: esters-buliding-blocks The author mentioned the following in the article:

The insect repellent Me salicylate elicits excitatory responses upon interaction with CquiOR32, an odorant receptor (OR) from the southern house mosquito, Culex quinquefasciatus. By contrast, eucalyptol binds to CquiOR32 to generate electrophysiol. and behavioral inhibitory responses. In an attempt to identify CquiOR32 variants displaying more robust inhibitory responses for more accurate current-voltage anal., we sequenced 31 CquiOR32 clones. In the Xenopus oocyte recording system, CquiOR32V2/CquiOrco-expressing oocytes yielded eucalyptol-elicited outward (inhibitory) currents relatively larger than Me salicylate-generated inward (excitatory) currents. Rescuing experiments showed that two of the amino acid substitutions in CquiOR32V2 located in a predicted transmembrane helix of the receptor are determinants of the outward/inward ratios. These findings, along with co-stimulus assays, suggest that odorant and inhibitor may bind to the same binding pocket. Current-voltage relationships obtained with standard perfusion buffer and those devoid of Na+ or Cl- indicated that both excitatory and inhibitory currents are mediated, at least in part, by cation. We then concluded that eucalyptol is an inverse agonist, which shifts the open closed equilibrium of the receptor toward the closed conformation, thus reducing the spontaneous activity. By contrast, the binding of Me salicylate shifts the equilibrium towards the open conformation and, consequently, leads to an increase in cation influx.Methyl Salicylate(cas: 119-36-8Category: esters-buliding-blocks) was used in this study.

Methyl Salicylate(cas: 119-36-8) has been used: as a component of clarifying solution for treating Mongolian gerbil cochlea intact for immunofluorescence analysis, as a plant elicitor to test its effect on reducing the whitefly population from tomato plants.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2019,Journal of the Science of Food and Agriculture included an article by Habibi, Fariborz; Ramezanian, Asghar; Rahemi, Majid; Eshghi, Saeid; Guillen, Fabian; Serrano, Maria; Valero, Daniel. Quality Control of Methyl Salicylate. The article was titled 《Postharvest treatments with γ-aminobutyric acid, methyl jasmonate, or methyl salicylate enhance chilling tolerance of blood orange fruit at prolonged cold storage》. The information in the text is summarized as follows:

Blood orange is sensitive to chilling injury (CI) depending on cultivar and storage temperature Postharvest treatments with γ-aminobutyric acid (GABA), Me jasmonate (MeJA), or Me salicylate (MeSA) are known to alleviate CI.γ-Aminobutyric acid aqueous solution, applied at 20 and 40 mM, was vacuum-infiltrated at 30 kPa for 8 min at 20°C. Me jasmonate or MeSA vapor treatments were applied seperately at 50 and 100μM by putting the fruit in 20 L plastic containers for 18 h at 20°C. There have been no reports about postharvest treatments of GABA, MeJA, or MeSA on enhancing the tolerance of ‘Moro’ blood orange to chilling during long-term cold storage at 3°C for 150 days, which was the subject of this study. All treatments significantly alleviated CI symptoms of blood orange manifested by lower electrolyte leakage (EL), malondialdehyde (MDA), hydrogen peroxide (H2O2) concentration, and higher proline content in flavedo during storage. The largest effects were obtained with 100, 50μM, and 40 mM for MeSA, MeJA, and GABA, resp., which enhanced the activity of the antioxidant enzymes catalase (CAT), ascorbate peroxidase (APX) and superoxide dismutase (SOD), and phenylalanine ammonia-lyase (PAL). On the other hand, these treatments suppressed peroxidase (POD) and polyphenol oxidase (PPO) activities. The mechanisms involved in enhancing the tolerance of ‘Moro’ blood orange to chilling could involve scavenging H2O2 by increasing the activity of antioxidant enzymes, higher PAL/PPO activity ratio, and osmoregulation by increasing proline content. These changes led to the maintenance of the epidermis structure. This was confirmed by SEM (SEM) micrographs. In the part of experimental materials, we found many familiar compounds, such as Methyl Salicylate(cas: 119-36-8Quality Control of Methyl Salicylate)

Methyl Salicylate(cas: 119-36-8) has been used: as a component of clarifying solution for treating Mongolian gerbil cochlea intact for immunofluorescence analysis, as a plant elicitor to test its effect on reducing the whitefly population from tomato plants.Quality Control of Methyl Salicylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics