Category: 112-63-0

Bebell, Lisa M.; Parks, Kalynn; Le, Mylinh H.; Ngonzi, Joseph; Adong, Julian; Boatin, Adeline A.; Bassett, Ingrid V.; Siedner, Mark J.; Gernand, Alison D.; Roberts, Drucilla J. published the artcile< Placental decidual arteriopathy and vascular endothelial growth factor A expression among women with or without human immunodeficiency virus>, Reference of 112-63-0, the main research area is placental decidual arteriopathy HIV infection VEGFA; Africa; Malperfusion; histology; immunohistochemistry; intra-uterine growth restriction; pathology; pregnancy; pregnant; resource-limited; small for gestational age.

Women with human immunodeficiency virus (HIV) (WHIV) are at higher risk of adverse birth outcomes. Proposed mechanisms for the increased risk include placental arteriopathy (vasculopathy) and maternal vascular malperfusion (MVM) due to antiretroviral therapy and medical comorbid conditions. However, these features and their underlying pathophysiol. mechanisms have not been well characterized in WHIV. We performed gross and histol. examination and immunohistochem. staining for vascular endothelial growth factor A (VEGF-A), a key angiogenic factor, on placentas from women with ≥1 MVM risk factors including: weight below the fifth percentile, histol. infarct or distal villous hypoplasia, nevirapine-based antiretroviral therapy, hypertension, and preeclampsia/eclampsia during pregnancy. We compared pathol. characteristics by maternal HIV serostatus. Twenty-seven of 41 (placentas 66%) assessed for VEGF-A were from WHIV. Mean maternal age was 27 years. Among WHIV, median CD4 T-cell count was 440/μL, and the HIV viral load was undetectable in 74%. Of VEGF-A-stained placentas, both decidua and villous endothelium tissue layers were present in 36 (88%). VEGF-A was detected in 31 of 36 (86%) with decidua present, and 39 of 40 (98%) with villous endothelium present. There were no differences in VEGF-A presence in any tissue type by maternal HIV serostatus (P = .28 to >.99). MVM was more common in placentas selected for VEGF-A staining (51 vs 8%; P < .001). VEGF-A immunostaining was highly prevalent, and staining patterns did not differ by maternal HIV serostatus among those with MVM risk factors, indicating that the role of VEGF-A in placental vasculopathy may not differ by maternal HIV serostatus. Journal of Infectious Diseases published new progress about Anti-HIV agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Douarre, Maxime; Marti-Centelles, Vicente; Rossy, Cybille; Pianet, Isabelle; McClenaghan, Nathan D. published the artcile< Regulation of Macrocycle Shuttling Rates in [2]Rotaxanes by Amino-Acid Speed Bumps in Organic-Aqueous Solvent Mixtures>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is amino acid rotaxane preparation mol shuttle steric effect.

A homologous series of two-station [2]rotaxanes incorporating amino-acid units in the mol. thread has been developed. The degenerate [2]rotaxanes exhibit amino-acid specific shuttling rates between two fumaric stations related to the steric factor associated to the amino-acid side chain, as demonstrated by variable-temperature 1H NMR spectroscopy and exchange spectroscopy (EXSY). This allows tuning of the macrocycle shuttling rate over 4 orders of magnitude, which has a relatively small solvent dependency.

European Journal of Organic Chemistry published new progress about Activation energy. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kongprawes, Grittima; Wongsawaeng, Doonyapong; Hosemann, Peter; Ngaosuwan, Kanokwan; Kiatkittipong, Worapon; Assabumrungrat, Suttichai published the artcile< Improvement of oxidation stability of fatty acid methyl esters derived from soybean oil via partial hydrogenation using dielectric barrier discharge plasma>, Computed Properties of 112-63-0, the main research area is fatty acid methyl ester soybean oil hydrogenation dielec barrier.

Oxidation stability is an important biodiesel property. One of the methods to improve oxidation stability is partially hydrogenated fatty acid Me esters (H-FAME). The present research studied the novel production technique of H-FAME derived from soybean FAME using non-thermal parallel-plate dielec. barrier discharge (DBD) plasma. This green hydrogenation method does not require a catalyst and can be performed under atm. pressure and at room temperature The reaction using DBD plasma could effectively initiate the hydrogenation reaction, and the results showed similar performance to catalysis technique. The optimized process parameters for 35 mL of FAME were 25% H2, 5.5 h of reaction time, and ambient temperature This condition exhibited the highest conversion of polyunsaturated FAMEs (C18:2 and C18:3) and the highest yield of C18:1. DBD plasma hydrogenation resulted in the reduction of iodine value from 128 to 67.4. The oxidation stability was enhanced from 2.13 to 10 h while the cloud point increased from -1°C to 11°C (still within the ASTM D6751 standard). This plasma process is a new alternative and eco-friendly method for H-FAME production

International Journal of Energy Research published new progress about Biodiesel fuel. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Computed Properties of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kobbelgaard, Sara; Brandes, Sebastian; Jorgensen, Karl Anker published the artcile< Asymmetric organocatalyzed [1,3]-sigmatropic rearrangements>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is beta amino acid asym preparation organocatalysis; sigmatropic rearrangement beta hydroxy ester cinchona alkaloid catalyst.

The first organocatalyzed enantioselective [1,3]-sigmatropic O- to N-rearrangement reactions are presented. The reactions take place under regio- and enantioselective control, and are catalyzed by cinchona alkaloids. Two reactions have been developed; the first one is the rearrangement of imidates to amides, while the other rearrangement occurs from carbamates to amines via a decarboxylation. Both transformations give nitrogen protected β-amino acid derivatives as the product. These novel asym. organocatalyzed [1,3]-sigmatropic O- to N-rearrangement reactions provide a reliable and efficient synthetic method for obtaining enantio-enriched β-amino acid derivatives in good yields from racemic starting materials.

Chemistry – A European Journal published new progress about [1,3]-Sigmatropic rearrangement (asym., O- to N-rearrangement reaction). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Castro-Granell, Vanessa; Garin, Noe; Jaen, Angeles; Cenoz, Santiago; Galindo, Maria Jose; Fuster-RuizdeApodaca, Maria Jose published the artcile< Prevalence, beliefs and impact of drug-drug interactions between antiretroviral therapy and illicit drugs among people living with HIV in Spain>, HPLC of Formula: 112-63-0, the main research area is drug interaction antiretroviral illicit agent HIV infection population.

Drug use implies important challenges related to HIV management, particularly due to an increased risk of potential interactions between antiretroviral therapy (ART) and illicit drugs (pDDIs). This study analyses the prevalence and severity of pDDIs among people living with HIV (PLHIV). It also explores their awareness of pDDIs and their beliefs about the toxicity that they may cause, as well as the impact of pDDIs on selected health variables. We conducted an online cross-sectional survey across 33 Spanish hospitals and NGOs to collect demographics and clin. data. pDDIs were checked against the Interaction Checker developed by Liverpool University. The sample of the present study was composed of 694 PLHIV who used illicit drugs. They represented 49.5% of the 1,401 PLHIV that participated in the survey. After excluding 38 participants due to lack of information on their ART or illicit drug use, 335 (51.1%) participants consuming drugs presented with some potentially significant pDDIs between their ART and illicit drugs, with a mean of 2.1±1.7 (1-10) pDDIs per patient. The drugs most frequently involved in pDDIs were cocaine, cannabis, MDMA and nitrates (“”poppers””). The prevalence of pDDIs across ART regimens was: protease inhibitors (41.7%); integrase inhibitor-boosted regimens (32.1%), and non-nucleoside reverse transcriptase inhibitors (26.3%). An awareness of pDDIs and beliefs about their potential toxicity correlated pos. with intentional non-adherence (p<0.0001). Participants with pDDIs exhibited a higher prevalence of intentional non-adherence (2.19±1.04 vs. 1.93±0.94; p = 0.001). The presence of pDDIs was not associated with poorer results in the clin. variables analyzed. A significant proportion of PLHIV who use drugs experience pDDIs, thereby requiring close monitoring. pDDIs should be considered in the clin. management of HIV patients. Adequate information about pDDIs and indicators about how to manage ART when PLHIV use drugs could improve ART non-adherence. PLoS One published new progress about Antiviral agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cheng, Bingxu; Wang, Chuanxi; Chen, Feiran; Yue, Le; Cao, Xuesong; Liu, Xiaofei; Yao, Yusong; Wang, Zhenyu; Xing, Baoshan published the artcile< Multiomics understanding of improved quality in cherry radish (Raphanus sativus L. var. radculus pers) after foliar application of selenium nanomaterials>, Category: esters-buliding-blocks, the main research area is selenium nanofertilizer crop yield Raphanus nanomaterial soil amendment metabolism; Crop yield and quality; Nano-enabled agriculture; Nanofertilizers; RNA-Seq and metabolomics; Radish; Selenium nanomaterials.

A selenium (Se)-nanoenabled agriculture strategy was established in this work to improve crop yield and quality. The results demonstrated that Se engineering nanomaterials (Se ENMs, 10 mg·L-1) were absorbed and translocated in cherry radish (Raphanus sativus L. var. radculus pers) from shoots to taproots after foliar application. RNA-Seq and metabolomic results indicated that the glucolysis, pyruvate and tricarboxylic acid (TCA) cycle metabolism pathways were accelerated by exposure to Se ENMs, resulting in increased production of flavonoids (3.2-fold), amino acids (1.4-fold), and TCA (2.5-fold) compared with the control. Moreover, Se content was enhanced by 5.4 and 2.6 times in pericarp and pulp upon Se ENMs exposure, resp., which was more efficient (2.2 and 1.1 times) than SeO32- treatment. Addnl., the yield of cherry radish was increased by 67.6% under Se ENMs, whereas SeO32- exposure only led to an increase of 7.4%. Therefore, the application of Se ENMs could reduce the amount of fertilizer used to minimize the environmental impact in agriculture while improve crop production and quality. These findings highlighted the significant potential of Se ENMs-enabled agriculture practices as an eco-friendly and sustainable crop strategy.

Science of the Total Environment published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Annapooranan, Raja; Wang, Yang; Cai, Shengqiang published the artcile< Highly Durable and Tough Liquid Crystal Elastomers>, Quality Control of 112-63-0, the main research area is polyurethane elastomer RM257 liquid crystal diethanethiol polymer; fatigue; fracture; interpenetrating networks; liquid crystal elastomer.

Liquid crystal elastomers (LCEs) are soft materials that exhibit interesting anisotropic and actuation properties. The emerging applications of thermally actuatable LCEs demand sufficient mech. durability under various thermomech. cycles. Although LCEs are tough at room temperature, they become very brittle at high temperature (above their actuation temperature), which can cause unexpected failure. We demonstrate a strategy to improve the high temperature fracture and fatigue properties of LCEs by designing interpenetrating polymer networks using a second polyurethane network. By selecting the appropriate composition of the polyurethane networks, the high temperature fracture and fatigue properties of LCEs were significantly enhanced, while retaining their actuation properties. The strategy from this work will help fabricate LCE-based actuators that are tough and durable at high temperatures and under cyclic loading.

ACS Applied Materials & Interfaces published new progress about Breaking strength. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Braun, Manfred; Devant, Ralf published the artcile< The (R)- and (S)-2-acetoxy-1,1,2-triphenylethanols - effective synthetic equivalents of a chiral acetate enolate>, Formula: C19H34O2, the main research area is aldehyde addition enolate stereochem; acetoxytriphenylethanol chiral acetate equivalent; carboxylic acid hydroxy.

The enolate I, easily available by double deprotonation of (R)-AcOCHPhCPh2OH, adds in a highly stereoselective manner to aldehydes RCHO (R = Ph, Me2CH, Pr). Hydrolysis of the adducts II and III affords the acids IV.

Tetrahedron Letters published new progress about Addition reaction. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lucchetti, Nicola; Tkacheva, Anastasia; Fantasia, Serena; Muniz, Kilian published the artcile< Radical C-H-Amination of Heteroarenes using Dual Initiation by Visible Light and Iodine>, COA of Formula: C19H34O2, the main research area is aminated heteroarene preparation crystal structure mol; heteroarene bis benzoisothiazolone dioxide iodobenzene photochem amination.

A novel light-induced C-H amination of heteroarenes was accomplished with preformed iodine(III) reagents as the combined oxidant and nitrogen source to obtain aminated heteroarenes I [R = Me, Bn, Boc, etc.; R1 = H, (CH2)2Br, Ph, etc.; R2 = H, 5-F, 4-Br, etc.] and II [Ar = 2-furyl, 1-Boc-2-pyrrolyl, 1-Boc-5-Et-2-pyrrolyl, etc.]. The reaction required the use of a small amount of mol. iodine, which under photochem. activation generated in situ an iodine(I) reagent as the initiator of the radical amination reaction.

Advanced Synthesis & Catalysis published new progress about Crystal structure. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mo, Nan; Zhu, Dan-dan; Liu, Jia-xin; Feng, Tianyi; Cui, Zhaoxia published the artcile< Metabolic responses to air-exposure stress of the Chinese mitten crab (Eriocheir sinensis) revealed by a combined analysis of metabolome and transcriptome>, COA of Formula: C19H34O2, the main research area is metabolic response air exposure stress Eriocheir sinensis combined analysis; metabolome transcriptome.

Air-exposure stress (AES) caused by aquacultural practises is detrimental to physiol. fitness and can lower the survival rate of cultured animals. Previous studies showed that AES could induce the readjustment of energy utilization, respiration, antioxidant production, and immune activity. To further understand the AES coping mechanism of Chinese mitten crabs, we applied an integrated metabolomic and transcriptomic anal. to study the hepatic metabolic responses when crabs were exposed to air at room temperature for 30 h or at lower temperature for 97 h. The metabolomic anal. showed that AES caused an increase in five carbohydrate-metabolism related metabolites and five lipid-metabolism related metabolites. Correspondingly, the transcriptomic anal. revealed the changed expression of eight genes which were related to carbohydrate or lipid metabolism In addition, our results showed that lowering temperature could alleviate the impacts of AES by depressing metabolic rates. Finally, our results demonstrated sexual dimorphism of lipid metabolism in Eriocheir sinensis.

Aquaculture published new progress about Air. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics