Category: 112-63-0

Basova, Liana; Lindsey, Alexander; McGovern, Anne Marie; Ellis, Ronald J.; Marcondes, Maria Cecilia Garibaldi published the artcile< Detection of H3K4me3 identifies neurohiv signatures, genomic effects of methamphetamine and addiction pathways in postmortem HIV+ brain specimens that are not amenable to transcriptome analysis>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is histone detection chromatin gene expression transcriptional profiling; H3K4me3; HIV; brain; methamphetamine; postmortem interval.

Human postmortem specimens are extremely valuable resources for investigating translational hypotheses. Tissue repositories collect clin. assessed specimens from people with and without HIV, including age, viral load, treatments, substance use patterns and cognitive functions. One challenge is the limited number of specimens suitable for transcriptional studies, mainly due to poor RNA quality resulting from long postmortem intervals. We hypothesized that epigenomic signatures would be more stable than RNA for assessing global changes associated with outcomes of interest. We found that H3K27Ac or RNA Polymerase (Pol) were not consistently detected by Chromatin Immunoprecipitation (ChIP), while the enhancer H3K4me3 histone modification was abundant and stable up to the 72 h postmortem. We tested our ability to use H3K4me3 in human prefrontal cortex from HIV+ individuals meeting criteria for methamphetamine use disorder or not (Meth +/-) which exhibited poor RNA quality and were not suitable for transcriptional profiling. Systems strategies that are typically used in transcriptional metadata were applied to H3K4me3 peaks revealing consistent genomic activity differences in regions where addiction and neuronal synapses pathway genes are represented, including genes of the dopaminergic system, as well as inflammatory pathways. The resulting comparisons mirrored previously observed effects of Meth on suppressing gene expression and provided insights on neurol. processes affected by Meth. The results suggested that H3K4me3 detection in chromatin may reflect transcriptional patterns, thus providing opportunities for anal. of larger numbers of specimens from cases with substance use and neurol. deficits. In conclusion, the detection of H3K4me3 in isolated chromatin can be an alternative to transcriptome strategies to increase the power of association using specimens with long postmortem intervals and low RNA quality.

Viruses published new progress about Activating transcription factor 2 Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lv, Hongyang; Zhang, Xiaorui; Ren, Yuanyuan; Zeng, Yijia; Fang, Qian; Fu, Qinwen; He, Dongmei; Yan, Zhuyun published the artcile< Title The Use of GC-MS and Network Pharmacology to Analyze the Material Basis and Mechanism of Ligusticum chuanxiong Hort. in Treating Chronic Cerebral Circulation Insufficiency>, Product Details of C19H34O2, the main research area is GCMS network pharmacol Ligusticum chuanxiong chronic cerebral circulation insufficiency.

Use Gas chromatog.-mass spectrometry technol. (GC-MS) to identify volatile chem. components in Ligusticum chuanxiong Hort. (LCH). The TCMSP and Swiss Target Prediction online platform were used to screen and predict the potential targets of the chem. components of LCH, and GeneCards, CTD, OMIM, DisGeNET, GEO databases were used to collect the potential targets of chronic cerebral circulation insufficiency (CCCI). A total of 50 volatile chem. components in LCH were analyzed and identified, and 126 potential targets for LCH treatment of CCCI were screened on this basis. Through further network topol. anal., 33 core components and 36 potential core targets were screened out. GO and KEGG enrichment anal. revealed that LCH played a therapeutic role through signaling pathways such as Neuroactive ligand-receptor interaction, Alzheimer disease, Pathways of neurodegeneration-multiple diseases, Proteoglycans in cancer, and Chem. carcinogenesis-receptor activation. The mol. docking results showed the top 4 active ingredients, Ligustilide, Terpineol, 3-Butylidenephthalide, and Linalool, and the top 5 core targets CREBBP, HSP90AA1, ESR1, VEGFA, and NR3 C1 all have good binding activity. The free energy is less than ≤-5 kcal/mol, and the mol. docking conformation is stable. LCH may improve the symptoms of CCCI by acting on inhibiting inflammatory factors, protecting nerve cells, and promoting angiogenesis pathways.

ChemistrySelect published new progress about Aliphatic compounds Role: ANT (Analyte), PKT (Pharmacokinetics), PUR (Purification or Recovery), THU (Therapeutic Use), ANST (Analytical Study), BIOL (Biological Study), PREP (Preparation), USES (Uses). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Janeeshma, Edappayil; Puthur, Jos T.; Wrobel, Jacek; Kalaji, Hazem M. published the artcile< Metabolic alterations elicited by Cd and Zn toxicity in Zea mays with the association of Claroideoglomus claroideum>, HPLC of Formula: 112-63-0, the main research area is Claroideoglomus claroideum Cadmium Zinc toxicity metabolic alterations Zea mays; Arbuscular Mycorrhiza – AM; Cadmium; GC-MS; Mycorrhiza; Phytochemistry; Zinc.

The concentrations of cadmium (Cd) and zinc (Zn) in arable lands exceed the maximum permissible levels due to the excessive use of phosphorus fertilizers and fungicides by farmers. The increasing issues related to the application of agrochems. have lead to the demand for the implementation of sustainable agricultural approaches. Association of arbuscular mycorrhizae with crop plants is an appropriate strategy due to the potential of these microorganisms to augment the metals tolerance of plants through the immobilization of Cd and Zn in an eco-friendly manner. In the present study, 45 d old Zea mays (var. CoHM6) plants inoculated with AM fungi (Claroideoglomus claroideum) were exposed to 1.95 g Zn Kg-1 soil and 0.45 g Cd Kg-1 soil. The major objective of this study was to determine the metabolic alterations in the leaves and roots of mycorrhizal and non-mycorrhizal plants exposed to CdCl2 and ZnSO4. Both non AM and AM plants exhibited alterations in the quantity of primary and secondary metabolites on exposure to Zn and Cd toxicity. Moreover, Zn and Cd-induced accumulation of gamma-sitosterol reduced the quantity of neophytadiene (a well-known terpenoid) and aided the production of 3-beta-acetoxystigmasta-4,6,22-triene in maize leaves. Mycorrhization and heavy metal toxicity induced significant metabolic changes in the roots by producing 4,22-stigmastadiene-3-one, eicosane, 9,19-cyclolanost-24-en-3-ol, pentacosane, oxalic acid, heptadecyl hexyl ester, l-norvaline, and n-(2-methoxyethoxycarbonyl). In addition, the metal-induced variations in leaf and root lignin composition were characterized with the aid of the FTIR technique. Mycorrhization improved the tolerance of maize plants to Cd and Zn toxicity by stabilizing these metal ions in the soil and/or limiting their uptake into the plants, thus ensuring normal metabolic functions of their roots and shoots.

Ecotoxicology published new progress about Claroideoglomus claroideum. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gale, Philip A.; Hiscock, Jennifer R.; Moore, Stephen J.; Caltagirone, Claudia; Hursthouse, Michael B.; Light, Mark E. published the artcile< Anion-anion proton transfer in hydrogen bonded complexes>, Product Details of C19H34O2, the main research area is dihydrogen phosphate anion proton transfer hydrogen bonded complex; crystallog dihydrogen phosphate hydrogen bond complex indolecarboxamide derivative.

Complexation of dihydrogen phosphate by an anion receptor containing six hydrogen bond donor groups (I,II,III,IV) has been shown to reduce the pKa of the bound anionic species to such an extent that addition of further aliquots of dihydrogen phosphate result in deprotonation of the bound species with the resultant formation of a monohydrogen phosphate receptor complex. X-ray crystallog. studies confirm monohydrogen phosphate complex formation in the solid state. In this way, this study explains the formation of complexes with unusual stoichiometries when investigating the binding of dihydrogen phosphate anion to hydrogen-bonding receptors.

Chemistry – An Asian Journal published new progress about Complexation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wu, Jingjie; Bao, Fengda; Ye, Xiaoxia; Li, Juan; Jiang, Jun published the artcile< Asymmetric Construction of Highly Functionalized Cyclobutanones Bearing Three Contiguous Stereogenic Centers by an Amino Acid Salt-Catalyzed Desymmetrization Reaction>, Formula: C19H34O2, the main research area is functionalized cyclobutanone preparation; cyclobutanone keto ester desymmetrization amino acid salt catalyzed.

An amino acid salt-catalyzed direct desymmetrization of 3-substituted cyclobutanones through a direct aldol reaction under mild reaction conditions was reported. The developed method provided an array of highly functionalized cyclobutanones bearing three contiguous stereogenic centers I [R = H, CO2Et; Ar = Ph, 2-FC6H4, 2-naphthyl, etc.; n = 1,2,3] in high yields and stereoselectivities with varied functional-group compatibility. Furthermore, the obtained adducts could be smoothly converted into polyfunctional 1,4-butyrolactones with maintained enantioselectivity.

Synlett published new progress about Cyclobutanones Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sun, Shiqin; Cheng, Xueli; Ma, Meiyuan; Liu, Yue; Wang, Guanghao; Yu, Hailong; Liu, Shiwei; Yu, Shitao published the artcile< High-efficient esterification of rosin and glycerol catalyzed by novel rare earth Lewis acidic ionic liquid: Reaction development and mechanistic study>, Product Details of C19H34O2, the main research area is ionic liquid catalyst rosin esterification glycerol reaction development.

As one of the most important modified products of rosin, rosin glyceride was widely used in many aspects. However, the preparation of rosin glyceride is always unfriendly due to the use of liquid catalyst, such as H2SO4 and H3PO4. The rosin glyceride with low acid value was synthesized in vacuum conditions using a novel Lewis acidic ionic liquid 1-butyl-3-methylimidazolium chloroscandinate[BuMeim][Sc2Cl7] as catalyst. The [BuMeim][Sc2Cl7] is of excellent catalytic activity and stability. The efficient catalytic activity was studied via the combined D. Functional Theory (DFT) and exptl. conditions. The DFT proved the free energy of the esterification could reach to 31.6 Kcal/mol, which illuminates that the excellent coordination of the anions and cations in the [BuMeim][Sc2Cl7] greatly reduces the reaction energy barrier and promotes the efficient progress of the reaction. As a result, [BuMeim][Sc2Cl7] is a good catalyst for the esterification of rosin and glycerol to prepare rosin glyceride. Furthermore, [BuMeim][Sc2Cl7] could be a potential catalysts for the other esterification.

Journal of the Taiwan Institute of Chemical Engineers published new progress about Esterification. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Huang, Wei-Ming; Liao, Wei-Sheng; Lai, Yan-Ming; Chen, I-Wen Peter published the artcile< Tuning the surface charge density of exfoliated thin molybdenum disulfide sheets via non-covalent functionalization for promoting hydrogen evolution reaction>, HPLC of Formula: 112-63-0, the main research area is molybdenum sulfide sheet electrocatalyst exfoliation surface charge density tuning.

The scalable and facile generation of hydrogen fuel via water splitting requires robust and cost-effective earth-abundant electrocatalysts for hydrogen evolution reaction (HER). It is reported for the first time that the surface charge d. of exfoliated monolayer molybdenum disulfide (MoS2) sheets can be successfully tuned with the assistance of exfoliants, such as pyridinium tribromide (py), imidazole (i.m.), and chlorophyll (ch), and thereby significantly affect the kinetics of the HER. The surface charge potential of the exfoliated monolayer py-MoS2, i.m.-MoS2, and ch-MoS2 sheets are -33 mV, -22 mV, and -2 mV, resp. As the surface charge potential approaches zero, the Tafel slope required varies from 140 mV dec-1 for py-MoS2 to 45 mV dec-1 for ch-MoS2. Moreover, to achieve real-world applications, the exfoliated thin ch-MoS2 sheets were fabricated to form flexible composite papers, and they exhibited excellent electrocatalytic activity with further enhanced Tafel slope of 35 mV dec-1, which is nearly identical to that of bulk Pt, “”the gold standard”” for HER, an ultra-low onset potential of -42 mV and over 100 h of electrochem. durability. This convenient non-covalent functionalization method provides opportunities for many other applications of exfoliated thin MoS2 sheets and other two-dimensional transition metal dichalcogenides (2D-TMDCs).

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about Carbon nanotubes. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sobhani, Sara; Fielenbach, Doris; Marigo, Mauro; Wabnitz, Tobias C.; Joergensen, Karl Anker published the artcile< Direct organocatalytic asymmetric α-sulfenylation of activated C-H bonds in lactones, lactams, and β-dicarbonyl compounds>, SDS of cas: 112-63-0, the main research area is cinchona alkaloid catalyst stereoselective sulfenylation lactone lactam dicarbonyl compound.

The application of cinchona alkaloid derivatives as catalysts for enantioselective α-sulfenylation of activated C-H bonds in lactones, lactams, and β-dicarbonyl compounds by different electrophilic sulfur reagents is presented. Optically active products are obtained in good to excellent yields and up to 91 % ee. Furthermore, the diastereoselective reduction of α-sulfenylated β-keto esters to give optically active α-sulfenylated β-hydroxy esters has been studied. A model for the intermediate is presented, in which the protonated cinchona alkaloid interacts with the substrate leading to face-shielding in accordance with the enantioselective α-sulfenylation step.

Chemistry – A European Journal published new progress about 1,3-Dicarbonyl compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Shi, Xiangyang; Cassagneau, Thierry; Caruso, Frank published the artcile< Electrostatic Interactions between Polyelectrolytes and a Titania Precursor: Thin Film and Solution Studies>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is electrostatic adsorption polyelectrolyte titania precursor; layer by layer self assembly titania film formation.

A facile approach, based on the polyelectrolyte-mediated electrostatic adsorption of a H2O-soluble TiO2 precursor, Ti (IV) bis (ammonium lactato) dihydroxide (TALH), is presented for the formation of multilayered thin films of defined thickness and composition The thin films were formed by the alternate deposition of TALH and pos. charged polyelectrolyte [poly(diallyldimethylammonium chloride), PDADMAC, poly(allylamine hydrochloride), PAH, and chitosan, CH] using electrostatic interactions for film formation. Layer-by-layer film growth was monitored by UV-visible spectrophotometry, ellipsometry, and by a quartz crystal microbalance (QCM). The UV-visible, ellipsometric, and QCM data all showed that a uniform amount of TALH was deposited with each alternate deposition cycle of polyelectrolyte and TALH, indicating that TALH binds to pos. charged polyelectrolytes. Using PDADMAC/TALH as a model system, the influence of drying on multilayer film formation was examined by QCM. These experiments showed that H2O-equilibrated multilayers facilitated the binding of TALH to PDADMAC. The electrostatic nature of the binding between TALH and pos. charged polyelectrolytes was confirmed by fluorescence studies in aqueous solution Removal of the anionic probe, pyrenetetrasulfonic acid (4-PSA), precomplexed to PDADMAC in aqueous solution, was observed upon the addition of TALH. PDADMAC/TALH multilayers were also constructed on colloid particles to gain insight into the binding behavior between the deposited species. The results suggest that multilayer film formation is facilitated via the deposition of oligomeric species of TALH. The approach presented here may be exploited for the fabrication of novel advanced TiO2-based materials (e.g. thin films, porous structures, and composite colloids).

Langmuir published new progress about Adsorption (electrostatic). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Okumura, Takefumi; Kawaji, Jun published the artcile< Research and development of thermally durable electrolyte for lithium ion battery>, Product Details of C19H34O2, the main research area is thermally durable electrolyte lithium ion battery.

For ensuring safety of lithium ion batteries (LIBs), we have extensively investigated the quasi-solid electrolyte where lithium ion conducive liquid is quasi-solidified at silica surfaces as thermally durable electrolyte, and applied it to high capacity and high energy d. LIB. For the liquid phase, a solvate ionic liquid, which is an equimolar complex of lithium bis(trifluoromethanesulfonyl)amide (LiTFSA) and tetraethylene glycol di-Me ether (G4), Li(G4)TFSA, was used. For enhancing discharge capability at a higher rate, Li(G4)TFSA was diluted by low viscos solvent such as propylene carbonate (PC). The developed electrolyte possessed a favorable volatilization temperature higher than 373 K. A 100-Wh-class laminated LIB with energy d. of 363 WhL-1 was fabricated by employing the electrolyte to graphite-LiNixCoyMnzO2 chem., and it generated neither fire nor smoke in a nail-penetration test. The result suggest that the developed LIB has high safety compared to a LIB comprised of a conventional organic liquid electrolyte. In addition, to enhance the cycle life of the LIB, the formation and growth mechanism of a solid-electrolyte interphase on a graphite-based neg. electrode was investigated. NMR and hard XPS revealed that the decompositions of LiTFSA, PC, and G4 contributed to the SEI formation at the initial charge, and that continuous decompositions of G4 and PC were a major reason for the SEI growth during charge-discharge cycles. Based on these anal., we have substituted a highly concentrated sulfolane based liquid which exhibits a high Li ion conductivity with less amount of the low viscos solvent, for the G4 based liquid The modification effectively improved the electrochem. durability of the electrolyte, leading to a higher capacity retention after charge-discharge cycle test.

Electrochemistry (Tokyo, Japan) published new progress about Battery electrolytes (Thermally Durable). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics