Category: 112-63-0

Chu, Kevin L.; Koley, Somnath; Jenkins, Lauren M.; Bailey, Sally R.; Kambhampati, Shrikaar; Foley, Kevin; Arp, Jennifer J.; Morley, Stewart A.; Czymmek, Kirk J.; Bates, Philip D.; Allen, Doug K. published the artcile< Metabolic flux analysis of the non-transitory starch tradeoff for lipid production in mature tobacco leaves>, Electric Literature of 112-63-0, the main research area is nontransitory starch lipid production tobacco leaf triacylglycerol; (13)C isotope Labeling; Acyl-ACPs; Carbon partitioning; Metabolic flux analysis; Nicotiana tabacum (tobacco); Starch-triacylglycerol tradeoff.

The metabolic plasticity of tobacco leaves has been demonstrated via the generation of transgenic plants that can accumulate over 30% dry weight as triacylglycerols. In investigating the changes in carbon partitioning in these high lipid-producing (HLP) leaves, foliar lipids accumulated stepwise over development. Interestingly, non-transient starch was observed to accumulate with plant age in WT but not HLP leaves, with a drop in foliar starch concurrent with an increase in lipid content. The metabolic carbon tradeoff between starch and lipid was studied using 13CO2-labeling experiments and isotopically nonstationary metabolic flux anal., not previously applied to the mature leaves of a crop. Fatty acid synthesis was investigated through assessment of acyl-acyl carrier proteins using a recently derived quantification method that was extended to accommodate isotopic labeling. Anal. of labeling patterns and flux modeling indicated the continued production of unlabeled starch, sucrose cycling, and a significant contribution of NADP-malic enzyme to plastidic pyruvate production for the production of lipids in HLP leaves, with the latter verified by enzyme activity assays. The results suggest an inherent capacity for a developmentally regulated carbon sink in tobacco leaves and may in part explain the uniquely successful leaf lipid engineering efforts in this crop.

Metabolic Engineering published new progress about Chloroplast. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kamoshita, Shione; Matsui, Saho; Suto, Nanako; Sakurai, Kaori published the artcile< Reactivity Analysis of New Multivalent Electrophilic Probes for Affinity Labeling of Carbohydrate Binding Proteins>, SDS of cas: 112-63-0, the main research area is electrophilic probe reactivity analysis affinity labeling carbohydrate binding protein; affinity labeling; carbohydrates; chemical probes; electrophiles; gold-nanoparticles; multivalency.

We have designed and synthesized six different multivalent electrophiles as carbohydrate affinity labeling probes. Evaluation of the reactivity of the electrophiles against peanut agglutinin (PNA) and Ricinus communis agglutinin (RCA) showed that p- and m-aryl sulfonyl fluoride are effective protein reactive groups that label carbohydrate binding lectins in a ligand-dependent fashion at a nanomolar probe concentration Anal. of the selectivity of affinity labeling in the presence of excess BSA as a nonspecific protein indicated that m-arylsulfonyl fluoride is a more selective protein-reactive group, albeit with attenuated reactivity. Further anal. showed that the labeling efficiency of the multivalent electrophilic probes can be improved by employing reaction conditions involving 25 °C instead of typically employed 4 °C. Both isomers of arylsulfonyl fluoride groups together represent promising affinity labels for target identification studies that could serve as more efficient alternatives to photoreactive groups.

ChemBioChem published new progress about Affinity labeling. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Majumdar, K. C.; Choudhury, P. K.; Biswas, P. published the artcile< Cyclization of 3-(2-cyclopenten-1-yl)-4-hydroxy[1]benzopyran-2-one>, Synthetic Route of 112-63-0, the main research area is cyclization cyclopentenylhydroxybenzopyranone; benzopyranone cyclopentenylhydroxy preparation cyclization; furochromone fused derivative preparation rearrangement; furocoumarin fused derivative preparation.

The title compound (I) was prepared by reaction of 3-chlorocyclopentene with 4-hydroxy[1]benzopyran-2-one. I or its acetate, on treatment with pyridine hydrotribromide in dichloromethane at 0-5° for 2 h, gave fused furochromone II in 90% yield. II, on refluxing in 50% sulfuric acid, underwent rearrangement to furnish fused furocoumarin III in 87% yield.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about Cyclization. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dutta, Arghya; Matsuda, Shoichi published the artcile< Identifying the Performance Limiters in High Areal-Capacity Li-Oxygen Battery at Subzero Temperatures>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is lithium oxygen battery subzero temperature.

Li-O2 batteries are found to show severe loss in energy d. at subzero temperatures Here we investigate and deconvolute several temperature dependent parameters of a high areal-capacity Li-O2 battery, and our analyses show that combined effects of electrode kinetics, diffusion of electroactive species in the electrolyte, and charge transport through the electrodes directly influence the temperature dependent average discharge potential of the cell. In contrast, the low capacity of Li-O2 cells at subzero temperatures is found to be the result of charge transport resistance in the Li2O2 layer and the diffusion limitation of electroactive species in the electrolyte.

ACS Applied Energy Materials published new progress about Battery electrodes. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Russell, Glen A.; Rhee, Jong Uk; Baik, Woonphil published the artcile< Electron transfer processes. Part 63. Reactions of p-nitrobenzyl halides with dialkyl phosphite anions in dimethyl sulfoxide>, COA of Formula: C19H34O2, the main research area is nitrobenzyl halide reaction dialkyl phosphite anion; solvent effect nitrobenzyl halide dialkyl phosphite.

The reactions of p-O2NC6H4CH2Cl with (RO)2PO- in Me2SO with R = Me, Et, Pr, Bu, CF3CH2, i-Pr, Ph involve the formation of p-O2NC6H4CH2P(O)(OR)2 by SN2 substitution followed by a further SRN1 p-nitro-benzylation of p-O2NC6H4CH[P(O)(OR)2]- and p-O2NC6H4C(CH2C6H4NO2-p)[P(O)(OR)2]-. With p-O2NC6H4CH2Br, the reactions proceed mainly to form p-O2NC6H4CH-2, which undergoes reaction with p-O2NC6H4CH2Br to form p-O2NC6H4CH2CH2C6H4NO2-p. Halophilic reaction of (RO)2PO- with p-O2NC6H4CH(CH3)X (X = Cl, Br) leading to the bibenzyl is the preferred reaction course. Reactions of (RO)2PO- or p-O2NC6H4CH[P(O)(OR)2]- with p-O2NC6H4CH2X in Me2SO do not form significant amounts of p-O2NC6H4CHX- that would yield p-O2NC6H4CH:CHC6H4NO2-p. However, p-Cl-C6H4CH[P(O)(OEt)]- readily abstracts the benzylic proton from p-O2NC6H4CH2X to form the stilbene, although p-O2NC6H4CH2Br reacts with p-O2NC6H4CH[P(O)(OR)2]- to form p-O2NC6H4CH(CH2C6H4No2-p)P(O)(OR)2 in a reaction mixture not inhibited by (t-Bu)2NO•.

Heteroatom Chemistry published new progress about Solvent effect. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Landwehr, Katherine R.; Hillas, Jessica; Mead-Hunter, Ryan; Brooks, Peter; King, Andrew; O’Leary, Rebecca A.; Kicic, Anthony; Mullins, Benjamin J.; Larcombe, Alexander N. published the artcile< Fuel feedstock determines biodiesel exhaust toxicity in a human airway epithelial cell exposure model>, HPLC of Formula: 112-63-0, the main research area is biodiesel fuel feedstock exhaust toxicity airway epithelial cell; Biodiesel; Exhaust exposure; Health; In vitro exposure model; Vehicle emissions.

Biodiesel is promoted as a sustainable replacement for com. diesel. Biodiesel fuel and exhaust properties change depending on the base feedstock oil/fat used during creation. The aims of this study were, for the first time, to compare the exhaust exposure health impacts of a wide range of biodiesels made from different feedstocks and relate these effects with the corresponding exhaust characteristics. Primary airway epithelial cells were exposed to diluted exhaust from an engine running on conventional diesel and biodiesel made from Soy, Canola, Waste Cooking Oil, Tallow, Palm and Cottonseed. Exhaust properties and cellular viability and mediator release were analyzed post exposure. The exhaust physico-chem. of Tallow biodiesel was the most different to diesel as well as the most toxic, with exposure resulting in significantly decreased cellular viability (95.8 ± 6.5%) and increased release of several immune mediators including IL-6 (+223.11 ± 368.83 pg/mL) and IL-8 (+1516.17 ± 2908.79 pg/mL) above Air controls. In contrast Canola biodiesel was the least toxic with exposure only increasing TNF-α (4.91 ± 8.61). This study, which investigated the toxic effects for the largest range of biodiesels, shows that exposure to different exhausts results in a spectrum of toxic effects in vitro when combusted under identical conditions.

Journal of Hazardous Materials published new progress about Biodiesel fuel. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Rui; Liu, Tingting; Chen, Jiayu; Zhang, Dianbao published the artcile< Paradol Induces Cell Cycle Arrest and Apoptosis in Glioblastoma Cells>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is paradol anticancer agent cell cycle arrest apoptosis.

Despite being the most common primary malignant tumor of the central nervous system, the prognosis of glioblastoma (GBM) is still remarkably poor. Paradol is a flavor phenolic constituent found in pepper and ginger, with anti-tumor, anti-inflammatory, and antioxidant activities. However, the effects of paradol on GBM cells remain unknown. In this study, we investigated the cytotoxicity of paradol on U-87 and U-251 GBM cells. Cell viability and Transwell assays revealed that paradol treatment markedly inhibited the viability and migration of GBM cells. Flow cytometry anal. showed G0/G1 cell cycle arrest, which was verified by the downregulation of CCNA and CCNB expression using western blotting. Paradol-induced cell apoptosis was confirmed by annexin V-FITC/PI staining and nuclear morphol. Furthermore, the phosphorylation of extracellular signal-regulated kinase (ERK) and p38 mitogen-activated protein kinase (MAPK) was determined by western blotting. Collectively, our data revealed that paradol inhibited cell viability and migration of GBM cells by inducing G0/G1 phase arrest and apoptosis, and activating ERK and p38 MAPK signaling.

Nutrition and Cancer published new progress about Antitumor agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Hai-Jun; Chen, Longrui; Oderinde, Martins S.; Edwards, Jacob T.; Kawamata, Yu; Baran, Phil S. published the artcile< Chemoselective, Scalable Nickel-Electrocatalytic O-Arylation of Alcohols>, COA of Formula: C19H34O2, the main research area is ether preparation chemoselective; alc aryl bromide arylation nickel electrocatalyst; O-Arylation; chemoselectivity; coupling; electrochemistry; nickel catalysis.

Herein a Ni-catalyzed electrochem. driven protocol to afford aryl-alkyl ether bonds through O-arylation of alcs. was depicted. This electrochem. method did not require strong base, exogenous expensive transition metal catalysts (e.g., Ir, Ru), and could easily be scaled up in either a batch or flow setting. Interestingly, e-etherification exhibited an enhanced substrate scope over the mechanistically related photochem. variant as it tolerated tertiary amine functional groups in the alc. nucleophile. with a broad substrate scope in an operationally simple way.

Angewandte Chemie, International Edition published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ennis, B. C.; Holan, George; Samuel, Eva L. published the artcile< 2-Trihalomethylbenzazoles. III. Reactions of 2-(trichloromethyl)benzimidazole with nucleophiles>, Electric Literature of 112-63-0, the main research area is BENZAZOLES; BENZIMIDAZOLES; IMIDAZOLES BENZ.

Nucleophilic displacements of Cl from 2-(trichloromethyl)benzimidazole (I) by water, alcs., phenols, and their S analogs are described. The special reactivity of the trichloromethyl group in this compound is compared with that of the trichloromethyl group in non-activated positions. The Friedel-Crafts reaction of 2-(trichloromethyl)benzimidazole with benzene is reported.

Journal of the Chemical Society [Section] C: Organic published new progress about Nucleophiles. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wu, Xiaohong; Wang, Xiaotong; Li, Zhengang; Chen, Libin; Zhou, Shiyuan; Zhang, Haitang; Qiao, Yu; Yue, Hongjun; Huang, Ling; Sun, Shi-Gang published the artcile< Stabilizing Li-O2 Batteries with Multifunctional Fluorinated Graphene>, Product Details of C19H34O2, the main research area is lithium oxygen battery electrolyte fluorinated graphene lithium metal anode; Li-metal anode; Li−O2 batteries; ORR; fluorinated graphene; superoxide.

As a full cell system with attractive theor. energy d., challenges faced by Li-O2 batteries (LOBs) are not only the deficient actual capacity and superoxide-derived parasitic reactions on the cathode side but also the stability of Li-metal anode. To solve simultaneously intrinsic issues, multifunctional fluorinated graphene (CFx, x = 1, F-Gr) was introduced into the ether-based electrolyte of LOBs. F-Gr can accelerate O2- transformation and O2–participated oxygen reduction reaction (ORR) process, resulting in enhanced discharge capacity and restrained O2–derived side reactions of LOBs, resp. Moreover, F-Gr induced the F-rich and O-depleted solid electrolyte interphase (SEI) film formation, which have improved Li-metal stability. Therefore, energy storage capacity, efficiency, and cyclability of LOBs have been markedly enhanced. More importantly, the method developed in this work to disperse F-Gr into an ether-based electrolyte for improving LOBs’ performances is convenient and significant from both scientific and engineering aspects.

Nano Letters published new progress about Battery anodes. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics