Category: 112-63-0

Lokhov, R. E. published the artcile< Kinetics of N-oxidation of compounds of the quinoline series and isomeric benzoquinolines by perbenzoic acid in chloroform and aqueous dioxane>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is oxidation quinoline benzoquinoline peroxybenzoic acid.

Rate constants and activation parameters were determined for the title reactions; a bimol. mechanism was indicated. Annelation of pyridine lowered its oxidation rate. The rate constant for oxidation of 4-amino-2,3-benzoquinoline was nearly an order of magnitude higher in CHCl3 than in aqueous dioxane. Correlations with nucleophilicity parameters and half-wave potentials for the reduction of the azine cations were discussed. The electron d. at N had a small effect; π conjugation between the substituent and the reaction center was an important factor.

Khimiya Geterotsiklicheskikh Soedinenii published new progress about Nucleophilicity. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Alekseyev, Roman S.; Amirova, Sabina R.; Terenin, Vladimir I. published the artcile< Synthesis of 5-chloro-7-azaindoles by Fischer reaction>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is azaindole preparation; hydrazinopyridine polyphosphoric acid Fischer cyclization.

A simple and effective method on the basis of Fischer reaction in polyphosphoric acid is proposed for the synthesis of previously unknown heterocyclic structures that contain the 5-chloro-1H-pyrrolo[2,3-b]pyridine system. This method can be used for the synthesis of 3-substituted and 2,3-disubstituted 5-chloro-7-azaindoles, e.g., I, with alkyl and aryl substituents.

Chemistry of Heterocyclic Compounds (New York, NY, United States) published new progress about Carbonyl compounds (organic) Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Yanyan; Yin, Shaojie; Chen, Xiaolan; Shi, Feifei; Wang, Jing; Yang, Haifeng published the artcile< The inhibitory effect of paeoniflorin on reactive oxygen species alleviates the activation of NF-κB and MAPK signalling pathways in macrophages.>, SDS of cas: 112-63-0, the main research area is MAPK; NF-κB; ROS; inflammation; macrophages; paeoniflorin.

Paeoniflorin (PF) has been proven to possess a protective effect in some inflammatory diseases, but the underlying mechanism remains unclear. Macrophages play central roles in inflammatory responses and LPS-stimulated RAW264.7 macrophage is an ideal model for studying the anti-inflammatory effects and mechanisms of drugs. Thus, it was used to explore the anti-inflammatory mechanism of PF in this study. The results showed that PF markedly attenuated the activation of NF-κB, extracellular signal-regulated kinase (ERK1/2) and p38 mitogen activated protein kinase (p38) signalling pathways induced by LPS exposure. In addition, PF pretreatment dose-dependently suppressed the production of cytokines and the expressions of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). Concomitantly, PF pretreatment dramatically inhibited the accumulation of intracellular reactive oxygen species (ROS) without affecting the phagocytosis of macrophages. Furthermore, it has proved the scavenging effect of PF on ROS was involved in the anti-inflammatory process. This study provides a novel aspect to the understanding of the anti-inflammatory mechanism of PF.

Microbiology (Reading, England) published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhu, Bo; Yan, Lin; Pan, Yuanhang; Lee, Richmond; Liu, Hongjun; Han, Zhiqiang; Huang, Kuo-Wei; Tan, Choon-Hong; Jiang, Zhiyong published the artcile< Lewis base catalyzed enantioselective allylic hydroxylation of Morita-Baylis-Hillman carbonates with water>, Electric Literature of 112-63-0, the main research area is alc enantioselective synthesis; Morita Baylis Hillman carbonate allylic hydroxylation Lewis base catalyst.

A Lewis base catalyzed allylic hydroxylation of Morita-Baylis-Hillman (MBH) carbonates has been developed. Various chiral MBH alcs. can be synthesized in high yields (up to 99%) and excellent enantioselectivities (up to 94% ee). This is the first report using water as a nucleophile in asym. organocatalysis. The nucleophilic role of water has been verified using 18O-labeling experiments

Journal of Organic Chemistry published new progress about Allylic alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Smith, Merry K.; Northrop, Brian H. published the artcile< Vibrational Properties of Boroxine Anhydride and Boronate Ester Materials: Model Systems for the Diagnostic Characterization of Covalent Organic Frameworks>, HPLC of Formula: 112-63-0, the main research area is vibrational spectra boroxine anhydride boronate ester.

The vibrational characteristics of 28 different boronic acid, boroxine anhydride, and boronate ester species have been systematically investigated using a combination of exptl. IR spectroscopy and computational modeling. IR bands characteristic to each boron-containing functionality have been categorized and assigned in conjunction with d. functional theory (B3LYP/6-31G(d)), with the aim of better understanding and distinguishing the vibrational characteristics of covalent organic frameworks (COFs) built from boronic acids. In several cases, vibrational assignments differ from those previously reported in the literature on boronic acid-based COFs. Vibrations commonly regarded as diagnostic for one functionality are found in regions of the IR spectrum where other functionalities also show characteristic peaks. The collective exptl. and computational results reveal that several alternative bands in the IR region can be used to more diagnostically distinguish between boronic acid, boroxine anhydride, and boronate ester species. The results presented herein provide the tools for straightforward characterization of boroxine anhydride and boronate ester species using IR spectroscopy. The results can be applied to addnl. theor. studies of larger COF-like assemblies as well as the anal. of other boronic-acid-based materials.

Chemistry of Materials published new progress about Conformational potential. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dong, Xiaochen; Su, Ching-Yuan; Zhang, Wenjing; Zhao, Jianwen; Ling, Qidan; Huang, Wei; Chen, Peng; Li, Lain-Jong published the artcile< Ultra-large single-layer graphene obtained from solution chemical reduction and its electrical properties>, HPLC of Formula: 112-63-0, the main research area is ultralarge single layer graphene elec property FET.

Graphene is a promising candidate for making next-generation nanoelectronic devices. Developing methods to produce large sized graphene with high yield is the key for graphene applications. Here, we report a simple method for large-scale production of ultra-large single-layer graphene sheet (≤50 μm) reduced from graphene oxides by hydrazine in the presence of aromatic tetrasodium 1,3,6,8-pyrenetetrasulfonic acid (TPA) which efficiently disperse the resulting graphene sheet in aqueous solutions Field-effect transistors can be readily fabricated using such large reduced graphene oxide sheets. The mobility of the reduced graphene oxide increases with the temperature of subsequent thermal reduction and reaches 3.5 cm2 V-1 s-1 after reduction at 1000°. Such solution-processable method is of great potential in printable fabrication of graphene-based devices.

Physical Chemistry Chemical Physics published new progress about Electric current-potential relationship. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Jarugu, Lokesh Babu; Reddy, China Anki; Chikkananjunda, Nanjundaswamy Kanikahalli; Krishnamoorthy, Suresh; Sarvanakumar, Pon; Sankar, Ulaganathan; Arunachalam, Pirama Nayagam; McDonald, Ivar M.; Olson, Richard E.; Rampulla, Richard; Mathur, Arvind; Gupta, Anuradha published the artcile< Process Optimization for the Large-Scale Preparation of (2S,3aR,7aS)-tert-Butyl Hexahydro-2,5-methanopyrrolo[3,2-c]pyridine-1(4H)-carboxylate, an Intermediate for Nicotinic Acetylcholine Receptor Agonists>, Formula: C19H34O2, the main research area is process optimization large scale preparation methanopyrrolopyridinecarboxylate; methanopyrrolopyridinecarboxylate preparation monoiodination Sonogashira coupling; one pot debenzylation ring hydrogenation methanopyrrolopyridinecarboxylate preparation.

An optimized large-scale synthesis of (2S,3aR,7aS)-tert-Bu hexahydro-2,5-methanopyrrolo[3,2-c]pyridine-1(4H)-carboxylate (I), an important intermediate for nicotinic acetylcholine receptor agonists, is described starting from the readily available and inexpensive 4-aminopyridine over in 10 steps in an overall yield of 14%. The key feature of the synthesis involves three transformations in a one-pot process, including debenzylation and ring hydrogenation of two fused bicyclic rings. Multihundred gram quantities of I were prepared

Organic Process Research & Development published new progress about Debenzylation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Borthwick, Alan D.; Foxton, Michael W.; Gray, Brian V.; Gregory, Gordon I.; Seale, Peter W.; Warburton, William K. published the artcile< 2-Nitrothizaoles>, Product Details of C19H34O2, the main research area is nitrothiazole bactericide; thiazole nitro bactericide; oxadiazole nitrothiazolyl bactericide; deamination aminothiazolyloxadiazole nitro Sandmeyer.

2-Nitrothiazole-5-carboxaldehyde oxime (I; R = CH:NOH) with propene oxide and COCl2 gave 60.5% I (R = CN) which with NH2OH gave 69% I [R = C(:NOH)NH2]. The latter with CH(OEt)3 and BF3.Et2O gave 48.5% 3-(2-nitrothiazol-5-yl)-1,2,4-oxadiazole (II; R = NO2, R1 = H). II (R = NH2, R1 = H), prepared in 4 steps from 2-aminothiazole-5-carboxaldehyde, with Cu and HNO2 gave 41% II (R = NO2, R1 = H) and 6% II (R = R1 = H). Similarly II (R = NH2, R1 = Me) gave 25% II (R = NO2, R1 = Me) and 20% II (R = H, R1 = Me). I (R = CHO) with 1,2,4-oxadiazol-3-ylmethyltriphenylphosphonium chloride and its 5-Me derivative gave 58 and 34% oxadizoles (III, R = H, and Me, resp.). The latter 2 compounds and II (R = NO2, R1 = H and Me) showed powerful antibacterial properties.

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about Deamination. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Katagiri, Takayuki; Amao, Yutaka published the artcile< Visible-light-induced enzymatic reactions using an NADH regeneration system of water-soluble zinc porphyrin and homogeneous colloidal rhodium nanoparticles>, COA of Formula: C19H34O2, the main research area is zinc porphyrin rhodium photocatalyst biocatalyst NADH regeneration.

The photo and biocatalyst hybrid system is one of the most ideal artificial photosynthetic systems using solar energy to synthesize various chems. and fuels. This study was devoted to achieving visible-light-driven mol. conversion with various enzymes using the NADH regeneration system consisting of an electron donor such as triethanol amine (TEOA), zinc tetraphenylporphyrin tetrasulfonate (ZnTPPS) as a photosensitizer and colloidal polyvinylpyrrolidone-dispersed rhodium nanoparticles (Rh-PVP) as a catalyst. The irradiation wavelength dependence of NADH regeneration with the system of TEOA, ZnTPPS, Rh-PVP and NAD+ was studied and the quantum efficiency for NADH regeneration at monochromatic 420 nm due to the Soret band of ZnTPPS was estimated to be ca. 0.0012%. This NADH regeneration system was also applied to various enzyme-catalyzed redox reactions. By using this NADH regeneration system in the presence of lactate or D-3-hydroxybutyrate dehydrogenases, various enantioselective mol. conversions by visible-light energy were accomplished. By using this NADH regeneration and malate dehydrogenase (decarboxylating), photo and biocatalytic CO2 fixation to organic mols. based on carbon-carbon bond formation between pyruvate and CO2 has been successfully achieved. The results not only show an example of colloidal metal nanoparticles used as a catalyst for selective NADH regeneration in general artificial photosynthesis but also the selective production of chems./solar fuels directly from CO2 with visible-light energy.

Sustainable Energy & Fuels published new progress about Enzymes Role: BSU (Biological Study, Unclassified), CAT (Catalyst Use), BIOL (Biological Study), USES (Uses). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Kui; Ren, Xiao-Wei; Cui, Jian-Hua; Guo, Jia-Shuang; Xing, Si-Yang; Dou, Hong-Xi; Wang, Meng-Meng published the artcile< Multistimuli Responsive Supramolecular Polymeric Nanoparticles Formed by Calixpyridinium and Chondroitin 4-Sulfate>, HPLC of Formula: 112-63-0, the main research area is calixpyridinium chondroitin sulfate supramol polymeric nanoparticle morphol optical property.

We have successfully constructed multistimuli responsive supramol. polymeric nanoparticles based on the complexation of calixpyridinium with polyanionic chondroitin 4-sulfate. The nanoparticles are disassembled upon increasing pH from 6 to 9, while a pH-responsive morphol. conversion from spherical nanoparticles to nanorods is observed upon decreasing pH from 6 to 2. Adding a competitive guest can also disrupt the assembly, representing the host-guest inclusion response. Interestingly, an unexpected hyaluronidase-responsive morphol. conversion from spherical nanoparticles to wire-like suprastructures rather than disassembly is also observed, as a result of the hyaluronidase-induced cleavage of chondroitin 4-sulfate. The multistimuli responsive morphol. conversion property with various dimensions, along with the facile preparation, will make this supramol. polymeric assembly approach well-suitable for a variety of important material applications.

ChemistrySelect published new progress about Aggregation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics