Category: 112-63-0

Zhao, Yaohong; Qian, Yihua; Su, Wei; Chen, Xi published the artcile< Application of molecular probe to investigate surface structure of metal passivator on copper>, Formula: C19H34O2, the main research area is copper sulfide surface structure metal passivator investigative.

Copper sulfide (Cu2S) contaminant is semi-conductive. Its formation and migration to insulating paper and oil caused insulation breakdown. Addition of benzotriazole derivatives as metal passivator slows down the corrosion process, as the metal passivator produces a protective layer on the copper surface, which prevents the reaction between corrosive sulfur and copper. But the surface structure of this impermeable film is still unknown. Herein we reported our investigation on the orientation of metal-passivator complex on copper surface by means of mol. probe. Ageing exptl. study with different steric and electronic groups in benzotriazole skeleton indicated that the second position of the mol. was sensitive to steric effect, suggesting end-on orientation preferable. Subsequently, SEM-EDX revealed the relative amount of copper sulfide on copper surface. Moreover, FTIR represented the characteristic wavenumber of C=O, C=N moiety and benzene skeleton of passivator-copper complex. XPS anal. delivered the organic elemental composition of the protective layer.

IEEE Transactions on Dielectrics and Electrical Insulation published new progress about Corrosion. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zaleskaya, Marta; Dobrzycki, Lukasz; Romanski, Jan published the artcile< Highly efficient, tripodal ion-pair receptors for switching selectivity between acetates and sulfates using solid-liquid and liquid-liquid extractions>, Computed Properties of 112-63-0, the main research area is tripodal ion pair receptor acetate sulfate solid liquid extraction; anion recognition; cation recognition; crown ether; host-guest interactions; ion pair receptors; squaramide.

A tripodal, squaramide-based ion-pair receptor 1 was synthesized in a modular fashion, and 1H NMR and UV-vis studies revealed its ability to interact more efficiently with anions with the assistance of cations. The reference tripodal anion receptor 2, lacking a crown ether unit, was found to lose the enhancement in anion binding induced by presence of cations. Besides the ability to bind anions in enhanced manner by the “”single armed”” ion-pair receptor 3, the lack of multiple and prearranged binding sites resulted in its much lower affinity towards anions than in the case of tripodal receptors. Unlike with receptors 2 or 3, the high affinity of 1 towards salts opens up the possibility of extracting extremely hydrophilic sulfate anions from aqueous to organic phase. The disparity in receptor 1 binding modes towards monovalent anions and divalent sulfates assures its selectivity towards sulfates over other lipophilic salts upon liquid-liquid extraction (LLE) and enables the Hofmeister bias to be overcome. By changing the extraction conditions from LLE to SLE (solid-liquid extraction), a switch of selectivity from sulfates to acetates was achieved. X-ray measurements support the ability of anion binding by cooperation of the arms of receptor 1 together with simultaneous binding of cations.

International Journal of Molecular Sciences published new progress about Anions. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Computed Properties of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yamaguchi, Akihiro; Okazaki, Mitsuo published the artcile< Preparation of p-nitrostilbene derivatives by the modified Wittig reaction>, Application of C19H34O2, the main research area is Wittig reaction nitro stilbenes; stilbenes nitro Wittig reaction; nitro stilbenes Wittig reaction; trialkyl phosphite benzyl halide; phosphite trialkyl benzyl halide; benzyl halide trialkyl phosphite.

PhCH2Cl (70 g) and 100 g (EtO)3P (I) heated at 150-70° for 18 hr gave 107 g PhCH2PO(OEt)2 (II), b25 171-5°. Treating 46.0 g II with a mixture of 75 ml HNO3 (d. = 1.38) and 75 ml H2SO4 at -3 to 0° gave 0.58:1 o-O2NC6H4CH2P(OEt)2 (III)-p-NO2 isomer (IV). Nitration of I with fuming HNO3 yielded 0.2:98.2 III-IV. Treating p-O2NC6H4CH2Br and o-O2NC6H4CH2Br with I gave pure IV, b3 199-201°, n20D 1.5212, and III, b1 167-8°, n20D 1.5082, resp. III (2.7 g) treated with 0.35 g Na in 20 ml EtOH and then with p-O2NC6H4CHO gave 95.2% p-O2NC6H4CH:CHC6H4NO2-p, m. 295-6°. Similarly the following p-O2NC6H4CH:CHC6H4R-p were prepared (R, % yield, and m.p. given): CN, 96.8, 255-6°; CO2H, 65.5, 333-4°; Cl, 92.3, 186-7°; Br, 93.1, 201-1.5; H, 94.2, 156.5-7.5°; Me, 80.8, 150-50.5°; MeO, 92.5, 131-2°; Me2N, 85.5, 252°; AcNH, 90.4, 256-7°. Similarly p-O2NC6H4CH:CHC6H3(NO2)2-2,4, m. 142.5-43°, was prepared in 80.3% yield.

Nippon Kagaku Zasshi published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Qin; Rao, Nian; Liu, Li; Le, Yi; Yan, Longjia published the artcile< Development of 5-trifluoromethylpyrimidine derivatives as dual inhibitors of EGFR and SRC for cancer therapy>, Electric Literature of 112-63-0, the main research area is trifluoromethylpyrimidine derivative EGFR inhibitor antitumor mol docking.

In this paper, we reported a new series of 5-trifluoromethylpyrimidine derivatives (I [R = 4-methoxyphenyl, 2-fluorophenyl, 3-fluorophenyl, etc.], II [R = Pr, iso-Pr, hexyl, etc.]) for cancer therapy. They were tested for antitumor activity in vitro on four human cancer cell lines including A549, K562, HepG2, MCF-7 and two kinase including wild type epidermal growth factor receptor tyrosine kinase (EGFRwt-TK) and c-Src. The results suggested that some of the compounds (I [ R = 4-methoxyphenyl, 2-fluorophenyl, 3-fluorophenyl, 3,4-difluorophenyl], II [R = hexyl, Et acetate, iso-Pr, cyclopentyl, cyclohexyl, tetrahydropyran] 6b, 6d, 6e, 6f, 6g, 6h) performed well activities. Especially 2-((2-((4-((2-(Cyclohexylamino)-3,4-dioxocyclobut-1-en-1-yl)amino)phenyl)amino)-5-(trifluoro- methyl)pyrimidin-4-yl)amino)-N-methylbenzamide (6g) showed high antitumor activities against four cancer cell lines with 1.08 μM, 2.06 μM, 1.24 μM and 2.57 μM, resp. Furthermore, compound 2-((2-((4-((2-(cyclohexylamino)-3,4-dioxocyclobut-1-en-1-yl)amino)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N-methylbenzamide inhibited EGFRwt and Src at the values of 0.75 μM and 0.15 μM.

Heterocycles published new progress about Antitumor agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Takagi, Toru; Itabashi, Yutaka; Tsuda, Takao published the artcile< High-performance liquid chromatographic separation of 2-hydroxy fatty acid enantiomers on a chiral slurry-packed capillary column>, Related Products of 112-63-0, the main research area is hydroxy fatty acid resolution HPLC; liquid chromatog resolution hydroxy fatty acid; nitrophenylurethane derivatization hydroxy fatty acid resolution.

Complete enantiomer separations of racemic 2-hydroxy fatty acids of C5-C16 as their 3,5-dinitrophenylurethane and Me ester derivatives were achieved by high-performance liquid chromatog. with a slurry-packed fused-silica capillary column (40 cm × 0.32 mm) inside diameter with a chiral phase, N-(S)-2-(4-chlorophenyl)isovaleroyl-p-phenylglycine ionically bonded to 5-μm silica gel. The anal. was optimized by using a ternary mobile phase, n-hexane-1,2-dichloroethane-ethanol, and UV detection at 226 nm.

Journal of Chromatographic Science published new progress about Chromatographic chiral resolution. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sun, Lei; Hu, Hua-Ping; Chen, Xiao-Xiao; Xu, Guo-Yong; Liu, Jin-Song; Hu, Jiang-Miao; Wu, De-Ling; Xu, Feng-Qing published the artcile< Two new acetoisovanillone glycosides from the water-soluble fraction of Paeonia ostii>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is Paeonia acetoisovanillone glycoside; Paeonia ostii T. Hong et J. X. Zhang; acetoisovanillone glycoside; water-soluble extraction.

The cortex root of Paeonia ostii, is used as a traditional Chinese medicine for treating female diseases. Phytochem. investigation of the water-soluble fraction of the plant led to the isolation of two new acetoisovanillone glycosides: acetoisovanillone-3-O-β-D-glucopyranoside (I) and 2-hydroxy-acetoisovanillone-3-O-β-D-glucopyranoside (II). Their structures were elucidated by extensive spectroscopic methods.

Natural Product Research published new progress about Bark (root). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dumitrescu, Dan; Dumitru, Florina; Legrand, Yves-Marie; Petit, Eddy; van der Lee, Arie; Barboiu, Mihail published the artcile< New ""Pyrene Box"" Cages for Adaptive Guest Conformations>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is Pyrene box cage adaptive guest conformation crystallog.

The possibility of controlling the compression extent and the coiling shape of the 1,12-diammoniumdodecane guest is shown by changing the dimensions of the internal space of the host guanidinium 1,3,5,8 pyrene-tetrasulfonate PTS4- crystalline capsules by using guanidinium (G+), amino-guanidinium (AG+), and diaminoguanidinium (A2G+) cations.

Organic Letters published new progress about Amines Role: PEP (Physical, Engineering or Chemical Process), RCT (Reactant), PROC (Process), RACT (Reactant or Reagent) (conjugate acids). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sorribes, Ivan; Wienhoefer, Gerrit; Vicent, Cristian; Junge, Kathrin; Llusar, Rosa; Beller, Matthias published the artcile< Chemoselective Transfer Hydrogenation to Nitroarenes Mediated by Cubane-Type Mo3S4 Cluster Catalysts>, Electric Literature of 112-63-0, the main research area is molybdenum sulfur cluster catalyst transfer hydrogenation nitro arene heteroarene; aromatic amine preparation.

Cubane-type Mo3S4 cluster compounds catalyzed transfer hydrogenation to nitro arenes or nitro heteroarenes to give aromatic amines. E.g., in presence of formic acid and NEt3 as the reducing agent, [Mo3S4H3(dmpe)2]BPh4 catalyzed the transfer hydrogenation of 4-O2NC6H4NH2 to give 90% p-phenylenediamine.

Angewandte Chemie, International Edition published new progress about Aromatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Wenchao; Li, Fashe; Wang, Hua published the artcile< Study of light wavelength on the oxidative stability of Jatropha biodiesel>, Quality Control of 112-63-0, the main research area is Jatropha biodiesel oxidative stability light wavelength.

The oxidative stability of Jatropha biodiesel after exposure to different wavelengths of visible light was studied and kinetic anal. of the oxidation process was carried out. The results showed that the induction period of Jatropha biodiesel was 5.12 h and visible light at different wavelengths affected the oxidation of biodiesel differently. Effect of oxidation was the strongest in the purple, where the induction period was reduced to 2.65 h. The red had the weakest effect on biodiesel oxidation, and the induction period was reduced to 4.61 h. Acid value detection, component anal. and UV characterization of biodiesel oxidized by visible light at different wavelengths. The results showed that with the decrease of light wavelength, the acid value of the biodiesel increased from 0.2577 mg KOH/g to 0.3438 mg KOH/g and the content of Me linoleate containing two carbon-carbon double bonds decreases. UV characterization results showed that the absorption peak absorbance of conjugated double bond of Jatropha biodiesel oxidized by purple light was 5.282, while the absorption peak absorbance of conjugated double bond of Jatropha biodiesel oxidized by red light was only 2.877, and purple light was helpful to stimulate the generation of conjugate double bond. The kinetic anal. results showed that the different wavelengths had different rates of biodiesel degradation Purple light has the fastest oxidation rate. The oxidation rate constant k1 was 0.06011, the reaction order was n = 1, and the min. activation energy of the oxidation reaction process was 19.79 kJ·mol-1.

Fuel published new progress about Activation energy. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Aziz, Nur Atiqah Mohamad; Hamid, Hamidah Abd; Yunus, Robiah; Abbas, Zulkifly; Omar, Rozita; Rashid, Umer; Syam, Azhari Muhammad published the artcile< Kinetics and thermodynamics of synthesis of palm oil-based trimethylolpropane triester using microwave irradiation>, Application In Synthesis of 112-63-0, the main research area is palm oil trimethylolpropane triester microwave irradiation.

Enhancement of reaction performance utilizing microwave irradiation has drawn so much interest due to its shorter reaction time and low catalyst loading. These advantages are particularly significant from kinetics and thermodn. perspectives. This study aimed to investigate the kinetics and thermodn. of microwave-assisted transesterification of palm oil-based Me ester into biolubricant. The transesterification reaction of palm oil Me ester (PME) and trimethylolpropane (TMP) was conducted at 110-130 °C for 90 min under vacuum condition. Sodium methoxide was employed as the catalyst at 0.6 wt% of reactants fixed at molar ratio of 4:1 (PME: TMP). The exptl. data were fitted with the second-order reversible reaction kinetics mechanisms. The data were solved via Runge-Kutta 4,5 order using MATLAB software. Anal. on the data revealed that the reaction rate constants at temperatures of 110-140 °C were in the range of 0.01-0.63 [(weight/weight)(min)]-1, with standard errors of 0.0026-0.0228 within 99.99% prediction interval. Microwave-assisted reaction obtained 17.0 kcal/mol of activation energy. This method reduced activation energy by 49% as compared to the conventional heating. Activation energy and time-periodic energy assessment showed that the reaction was endothermic. The reaction at 130 °C is the easiest to activate. The pos. Gibbs free energy (ΔG > 0) found using Eyring-Polanyi equation indicated that the transesterification was non-spontaneous and endergonic.

Journal of Saudi Chemical Society published new progress about Activation energy. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics