Category: 112-63-0

Cutler, C. A.; Burrell, A. K.; Officer, D. L.; Too, C. O.; Wallace, G. G. published the artcile< Effect of electron withdrawing or donating substituents on the photovoltaic performance of polythiophenes>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is thiophene nitrophenyl cyanophenyl dimethylaminophenyl substituent preparation galvanostatic polymerization; bithiophene styrylthiophene copolymer preparation redox state conductivity; photovoltaic response bithiophene styrylthiophene copolymer substituent effect.

Bithiophene copolymers with p-(E)-3-styrylthiophenes were prepared by electrochem. polymerization and characterized by cyclic voltammetry, UV-VIS spectrophotometry, elemental anal., and four point probe conductivity measurements. The monomers 1-(4”-Nitrophenyl)-2-(3′-thienyl)ethene, 1-(4”-cyanophenyl)-2-(3′-thienyl)ethene, and 1-(4”-Dimethylaminophenyl)-2-(3′-thienyl)ethene were first prepared, then the copolymers were prepared under galvanostatic conditions. The ratio of bithiophene to substituted thiophene units was as high as 8:1. The effects of electron withdrawing groups (-NO2 and -CN) and the electron donating group -NMe2 on. The homopolymer and copolymers had low conductivity, yet the UV-VIS spectra still showed the expected differences in absorbance between fully oxidized (conducting) and fully reduced (semiconducting) states. Spectral differences were also observed when the polythiophenes were partially oxidized. Fully oxidized polymers showed negligible photovoltaic response. Partially oxidized copolymers with -CN and -NMe2 substituted thiophene groups showed photovoltaic response at 500 V. The polymers were evaluated in terms of photovoltaic output using a photoelectrochem. test cell structure with liquid electrolyte and ITO working electrodes. The copolymers with electron-withdrawing NO2 groups showed better response than that of copolymers containing electron-donating NMe2 groups.

Synthetic Metals published new progress about Electric conductivity. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Nan; Zhang, Yao; Jiang, Huan-Huan; Du, Guo-Wei; Pan, Qiang; Xiong, Ren-Gen; Zhang, Han-Yue published the artcile< Enantiomeric Hydrogen-bonded Chains Driving Ferroelectric and Nonlinear Optical Behavior>, Category: esters-buliding-blocks, the main research area is ferroelec enantiomer homochirality ferroelasticity crystal structure.

Organic multiferroic materials have been widely investigated due to their novel phys. properties and broad applications. However, the discovery of organic small-mol. multiferroic compounds is still rare. Herein, based on the chem. design strategy of introducing homochirality, we present a pair of enantiomeric organic small-mol. compounds [HDABCO (1,4-diazabicyclo[2.2.2]octonium)][L- and D-MA (malic acid)], which displays high Curie temperatures (Tc) of 409/412 K, superior optoelectronic performance, and unique ferroelec. and ferroelastic nature. In comparison with the reported ferroelecs. with the [HDABCO]+ cation chain structure, the enantiomers show a neutral one-dimensional chain, where hydrogen bonds connect [HDABCO]+ cations and [MA]- anions. Strikingly, [HDABCO][L- and D-MA] exhibit a large second harmonic generation (SHG) intensity of about 2.46 and 2.53 times that of KH2PO4 (KDP), exceeding those of all the organic ferroelecs. (about 0.2-1 x KDP). With excellent SHG signal and ferroic properties, as well as the merit of low acoustic impedance z0 matching that of the body and easy processing, [HDABCO][L- and D-MA] are potential candidates for future biocompatible electronic devices with multi-functionality.

Chemistry of Materials published new progress about Acoustic impedance. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Schoss, Katja; Kocevar Glavac, Nina; Dolenc Koce, Jasna; Anzlovar, Sabina published the artcile< Supercritical CO2 Plant Extracts Show Antifungal Activities against Crop-Borne Fungi>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is supercritical carbon dioxide plant extract fungus antifungal activity; Botrytis cinerea; Chamomilla recutita; antifungal activity; growth inhibition; plant extract; supercritical CO2 extraction.

Fungal infections of cultivated food crops result in extensive losses of crops at the global level, while resistance to antifungal agents continues to grow. Supercritical fluid extraction using CO2 (SFE-CO2) has gained attention as an environmentally well-accepted extraction method, as CO2 is a non-toxic, inert and available solvent, and the extracts obtained are, chem., of greater or different complexities compared to those of conventional extracts The SFE-CO2 extracts of Achillea millefolium, Calendula officinalis, Chamomilla recutita, Helichrysum arenarium, Humulus lupulus, Taraxacum officinale, Juniperus communis, Hypericum perforatum, Nepeta cataria, Crataegus sp. and Sambucus nigra were studied in terms of their compositions and antifungal activities against the wheat- and buckwheat-borne fungi Alternaria alternata, Epicoccum nigrum, Botrytis cinerea, Fusarium oxysporum and Fusarium poae. The C. recutita and H. arenarium extracts were the most efficacious, and these inhibited the growth of most of the fungi by 80% to 100%. Among the fungal species, B. cinerea was the most susceptible to the treatments with the SFE-CO2 extracts, while Fusarium spp. were the least. This study shows that some of these SFE-CO2 extracts have promising potential for use as antifungal agents for selected crop-borne fungi.

Molecules published new progress about Achillea millefolium. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Romanov-Michailidis, Fedor; Besnard, Celine; Alexakis, Alexandre published the artcile< N-Heterocyclic Carbene-Catalyzed Annulation of α-Cyano-1,4-diketones with Ynals>, Reference of 112-63-0, the main research area is heterocyclic carbene catalyst cyclization cyano diketone ynal; furopyranone stereoselective preparation.

In this paper, the first stereoselective annulation reaction between α-cyano-1,4-diketones and ynals, mediated by catalytic amounts of a triazolium salt precatalyst and cocatalytic amounts of a weak carboxylate base, is disclosed. The title transformation proceeds smoothly under mild reaction conditions and generates three contiguous stereogenic centers, one of which is a quaternary acetal carbon. This reaction tolerates a wide variety of electronically distinct substituents on both reaction partners and affords privileged bicyclic scaffolds, e.g. I, in 61-90% isolated yields and with up to 20:1 diastereomeric preference.

Organic Letters published new progress about Alkynals Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Petrenko, Daria; Chubarev, Vladimir; Syzrantsev, Nikita; Ismail, Nafeeza; Merkulov, Vadim; Sologova, Susanna; Grigorevskikh, Ekaterina; Smolyarchuk, Elena; Alyautdin, Renad published the artcile< Temozolomide Efficacy and Metabolism: The Implicit Relevance of Nanoscale Delivery Systems †>, Product Details of C19H34O2, the main research area is MTIC; drug delivery systems; glioblastoma; nanocarriers; nanoparticles (NP); temozolomide (TMZ).

The most common primary malignant brain tumors in adults are gliomas. Glioblastoma is the most prevalent and aggressive tumor subtype of glioma. Current standards for the treatment of glioblastoma include a combination of surgical, radiation, and drug therapy methods. The drug therapy currently includes temozolomide (TMZ), an alkylating agent, and bevacizumab, a recombinant monoclonal IgG1 antibody that selectively binds to and inhibits the biol. activity of vascular endothelial growth factor. Supplementation of glioblastoma radiation therapy with TMZ increased patient survival from 12.1 to 14.6 mo. The specificity of TMZ effect on brain tumors is largely determined by special aspects of its pharmacokinetics. TMZ is an orally bioavailable prodrug, which is well absorbed from the gastrointestinal tract and is converted to its active alkylating metabolite 5-(3-Me triazen-1-yl)imidazole-4-carbozamide (MTIC) spontaneously in physiol. condition that does not require hepatic involvement. MTIC produced in the plasma is not able to cross the BBB and is formed locally in the brain. A promising way to increase the effectiveness of TMZ chemotherapy for glioblastoma is to prevent its hydrolysis in peripheral tissues and thereby increase the drug concentration in the brain that nanoscale delivery systems can provide. The review discusses possible ways to increase the efficacy of TMZ using nanocarriers.

Molecules published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Farag, Mohamed A.; Fahmy, Sherifa; Choucry, Mouchira A.; Wahdan, Mariam O.; Elsebai, Mahmoud Fahmi published the artcile< Metabolites profiling reveals for antimicrobial compositional differences and action mechanism in the toothbrushing stick ""miswak"" Salvadora persica>, Reference of 112-63-0, the main research area is metabolite profile antimicrobial toothbrush miswak Salvadora benzyl isothiocyanate; Antimicrobial activity; Benzyl isothiocyanate; GC–MS; Metabolomics; S. persica; Solid phase microextraction.

Among many plant species suitable for preparing toothbrushing sticks, miswak (Salvadora persica, family Salvadoraceae) is found the most effective tool for oral hygiene. S. persica possesses antibacterial, antiviral and antifungal effects against oral microbes, mostly due to its benzyl isothiocyanate content. To provide insight into S. persica chem. composition, volatile constituents from roots and stems of S. persica grown in Egypt and Saudi Arabia were profiled using solid-phase microextraction (SPME) coupled to gas chromatog.-mass spectrometry (GC-MS). A total of 21 volatiles were identified with sulfur compounds amounting for the major volatile class. Orthogonal projection to latent structures-discriminant anal. (OPLS-DA) revealed for benzyl isothiocyanate (BITC) enrichment in roots vs. stems. Primary metabolites contributing to S. persica taste viz. sugars and organic acids were profiled using GC-MS with silylation. Polyols (sugars) viz. arabitol, meso-erythritol, and mannitol were found to predominate sugars composition in S. persica stems being most enriched in meso-erythritol. The impact of saliva on S. persica aroma profile was further assessed and revealing for no enhancement in BITC production with salivation, and further not being detected in toothpaste preparation claimed to contain S. persica extract This study provides the most complete profile of volatiles, sugars, and organic acids in S. persica organs and more rationalizing its use as a toothbrush.

Journal of Pharmaceutical and Biomedical Analysis published new progress about Antibacterial agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Petropolis, Nicholas P.; Petropolis, Harrison M.; MacNeil, Nicole E.; Doucet, Taylor M.; Marangoni, D. Gerrard published the artcile< The Interaction of Glymes with Surfactant Micelles>, Application In Synthesis of 112-63-0, the main research area is glyme surfactant micelle interaction.

The critical micelle concentrations (CMC) values and counterion dissociation (α values) have been determined for a number of mixed micellar systems consisting of two typical ionic surfactants and glycol ethers (glymes) as cosurfactants, namely diethylene glycol di-Me ether, diethylene glycol di-Et ether, triethylene glycol di-Me ether, and tetraethylene glycol di-Me ether. Conductance experiments were used to determine the CMC and α values of the mixed micelles as a function of glyme concentration in the aqueous mixed solvent. Favorable interactions between sodium dodecyl sulfate micelles and glyme cosurfactants were deduced from the decreases in the CMC values and the large increase in the α values of these systems as a function of increasing glyme concentration in the mixed solvents. In contrast to the anionic surfactant/glyme systems, in general, there appeared to be little favorable interactions between the surfactant and glymes when micelles of the cationic surfactant dodecyltrimethylammonium bromide were formed in water/glyme solvent systems containing an increasing amount of the glymes. The interaction of glymes with the surfactant micelles was examined closely via 13C NMR (NMR) chem. shifts for both surfactant and glyme carbons; these chem. shifts changes were interpreted in terms of the distribution and the localization of the glymes in the aggregates. Finally, partition constants, determined from two-dimensional diffusion-oriented spectroscopy (2D-DOSY) experiments, were used to calculate thermodn. quantities of transfer of the glymes between the bulk phase and the self-assembled aggregates. All these results are interpreted in terms of the key contributions that both the glyme ethoxylated groups and alkyl endgroups make to the hydrophobic interactions.

Journal of Surfactants and Detergents published new progress about Aggregates. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Feng, Yaqing; Zhang, Xiaodong; Zhang, Weihong published the artcile< Synthesis of spiro-thiazole-imidazole compound>, Synthetic Route of 112-63-0, the main research area is spiroimidazobenzothiazolecyclohexane preparation.

2-Amino-4,5-dihydrospiro[benzo[d]thiazole-6(7H),1′-cyclohexane] was prepared by the reaction of spiro[5.5]undecane-3-one with thiourea in the presence of iodine, and was condensed with p-chlorophenacyl bromide in benzene to give, after cyclization, 2-(p-chlorophenyl)-5,8-dihydrospiro[imidazo[2,1-b]benzo[d]thiazole-7(6H),1′-cyclohexane] (I). Crystal structure of I was determined

Hecheng Huaxue published new progress about Crystal structure. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Han, Guangdian; Wen, Hongyan published the artcile< A new method for aromatization of Δ5(10)-steroidal C3-dimethyl ketals>, COA of Formula: C19H34O2, the main research area is aromatization steroid dimethyl ketal.

The aromatization of Δ5(10)-steroidal C3-dimethyl ketals I (R = Et, XY = O; R = Et, X = OH, OAc, Y = H; R = Et, X = OH, Y = CCH; R = Me, X = OH, OAc, Y = H) by pyridinium hydrobromide perbromide gave aromatic steroids II in yields of 90-95%.

Chinese Chemical Letters published new progress about 19-Norsteroids Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Heaysman, Clare L.; Phillips, Gary J.; Lloyd, Andrew W.; Lewis, Andrew L. published the artcile< Synthesis and characterization of cationic quaternary ammonium-modified polyvinyl alcohol hydrogel beads as a drug delivery embolization system>, COA of Formula: C19H34O2, the main research area is cationic quaternary ammonium polyvinyl alc hydrogel bead drug delivery.

To extend the platform of clin. utilized chemoembolic agents based on ion-exchange systems to support the delivery of anionic drugs, a series of PVA-based beads was produced with different levels of (3-acrylamidopropyl)trimethylammonium chloride (APTA) in their formulation. The beads were characterized to confirm composition and the effect of formulation variation on phys. properties was assessed. Suspension polymerization was shown to successfully produce uniformly spherical copolymer beads with APTA content up to 60%. Equilibrium water content and resistance to compression both increased with increasing APTA content in the formulation. Confocal laser scanning microscopy was used with model drugs to demonstrate that by increasing APTA content, compounds between the mol. weight range 70-250 kDa could permeate the microsphere structures. Interaction with anionic drugs was modelled using multivalent dyes. Dyes with multi-binding sites had increased interaction with the polymer, slowing the release and also demonstrating a reduced rate of elution from beads with higher charge d. The model drug release studies demonstrate that these systems can be engineered for different potential anionic drugs for local therapeutic delivery in the clinic.

Journal of Materials Science: Materials in Medicine published new progress about Electric charge. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics