Category: 112-63-0

Tishinov, Kiril; Schmidt, Kristina; Haeussinger, Daniel; Gillingham, Dennis G. published the artcile< Structure-Selective Catalytic Alkylation of DNA and RNA>, Related Products of 112-63-0, the main research area is structure selectivity catalytic alkylation DNA RNA.

The authors established that rhodium-catalyzed carbene transfer is a viable means of achieving the selective alkylation of a variety of NAs. Moreover its predictable selectivity profile allows the strategic targeting of unpaired nucleobases such as those present in single strands, bulge regions, and overhangs. Key features of the present process are its simplicity and directness: the catalyst is com. available, the diazo compounds are readily prepared, and native NAs are viable substrates. Challenges for future development include further refining the base specificity and achieving efficient alkylation at high dilution Given the enormous excess of water present, the preference for N-H insertion observed here, as well as by others in the protein-labeling field, is intriguing. The new catalytic alkylation process offers a powerful strategy in the labeling and modification of NA derivatives, a strategy which may be applied to the tailoring of DNA architectures and in the labeling of NAs for biol. study or therapeutic applications.

Angewandte Chemie, International Edition published new progress about Alkylation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Toudert, Nadia; Zakkad, Farida; Dadda, Noureddine; Djilani, Abdelouaheb; Dicko, Amadou; Djilani, Salah Eddine published the artcile< Phytochemical analysis of bioactive extracts and seed oil of three euphorbia species from Algerian flora by LC-MS and GC-MS>, Application In Synthesis of 112-63-0, the main research area is euphorbia species seed oil bioactive extract phytochem analysis; phytochem analysis LC GC MS.

Euphorbia species possess pharmacol. properties that have been widely used for medical purposes worldwide. In this paper, three plants belonging to the Euphorbia genus growing in North-East of Algeria were studied. The phenolic contents were identified using LC-MS, while the fatty acid composition of their fixed oils was determined with GC-MS. The quantification of the total condensed tannins and the leaves’ entire anthocyanin content were performed using photometric methods. The main constituents of the polyphenolic compounds identified by LC-MS were ascorbic, chlorogenic, and ellagic acids. The oil yield of the seeds of E. terracina, E. biumbellata, and E. dendroides was 17.48%, 18.5%, and 20.05%, resp. Quant. analyses of these oils using GC-MS showed variations in the species’ fatty acid constituents’ concentrations and compositions Besides, the phytochem. screening results showed that E. terracina possessed a high amount of tannin and anthocyanin content compared with other studied plants.

Indonesian Journal of Chemistry published new progress about Anthocyanins Role: ANT (Analyte), BSU (Biological Study, Unclassified), ANST (Analytical Study), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Yaxin; Yang, Le; Liu, Shuai; Huang, Lixia; Liu, Zhong-Quan published the artcile< Surgical Cleavage of Unstrained C(sp3)-C(sp3) Bonds in General Alcohols for Heteroaryl C-H Alkylation and Acylation>, Synthetic Route of 112-63-0, the main research area is alc azaarene iodine promotor photochem Minisci reaction; alkyl azaarene preparation green chem regioselective.

A predictable and surgical cleavage of carbon-carbon bond in alcs. A wide range of 1°, 2° and 3° alcs. including sugars and steroids without ring strain or steric hindrance were all compatible with this system. Also it offered a green and practical strategy for generation of alkyl/acyl radicals using alcs. as the sources. Besides, the features of visible-light-initiation, catalyst and metal free, excellent selectivity and mild conditions made it valuable and attractive.

Advanced Synthesis & Catalysis published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yang, Bo; Yang, Wu; Guo, Yonghong; You, Lijun; He, Chuan published the artcile< Enantioselective Silylation of Aliphatic C-H Bonds for the Synthesis of Silicon-Stereogenic Dihydrobenzosiloles>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is rhodium catalyzed enantioselective silylation cyclization styrene derivative arylsilane; silicon stereogenic dihydrobenzosilole containing dehydrocholesterol preparation crystal structure; mol structure silicon stereogenic dihydrobenzosilole containing dehydrocholesterol; C(sp3)−H silylation; asymmetric catalysis; dihydrobenzosiloles; hydrosilylation; silanes.

A Rh(I)-catalyzed enantioselective silylation of aliphatic C-H bonds for the synthesis of Si-stereogenic dihydrobenzosiloles is demonstrated. This reaction involves a highly enantioselective intramol. C(sp3)-H silylation of dihydrosilanes, followed by a stereospecific intermol. alkene hydrosilylation leading to the asym. tetrasubstituted silanes. A wide range of dihydrosilanes and alkenes displaying various functional groups are compatible with this process, giving access to a variety of highly functionalized Si-stereogenic dihydrobenzosiloles in good to excellent yields and enantioselectivities.

Angewandte Chemie, International Edition published new progress about Crystal structure. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Jin, Ming-Yu; Kim, Sun-Min; Han, Hog-Yu; Ryu, Do-Hyun; Yang, Jung-Woon published the artcile< Switching Regioselectivity in Crossed Acyloin Condensations between Aromatic Aldehydes and Acetaldehyde by Altering N-Heterocyclic Carbene Catalysts>, Reference of 112-63-0, the main research area is asym crossed acyloin condensation chiral catalyst; regioselectivity acyloin condensation aromatic aldehyde acetaldehyde heterocyclic carbene catalyst.

An unprecedented high level of regioselectivities (up to 96%) in the intermol. crossed acyloin condensations of various aromatic aldehydes with acetaldehyde was realized by an appropriate choice of N-heterocyclic carbene catalysts.

Organic Letters published new progress about Acyloin condensation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

He, Linhua; Mei, Yukui; Peng, Zhulun published the artcile< Synthesis of diclazuril>, Quality Control of 112-63-0, the main research area is diclazuril preparation protozoacide.

The protozoacide Diclazuril was synthesized by substituting 3,4,5-trichloronitrobenzene with 4-chlorophenylacetonitrile in the presence of NaOH, reducing with Fe/NH4Cl, diazotizing with NaNO2/HCl and adding with Et cyanoacetylcarbamate to obtain Et [2-[4-(4-chlorophenylcyanomethyl)-3,5-dichlorophenylhydrazo]-2-cyanoacetyl]carbamate, cyclizing intramolecularly in acetic acid in the presence of KOAc under refluxing for 2 h, and hydrolyzing and decarboxylating with 36% HCl and mercaptoacetic acid under refluxing for 8 h, etc.

Zhongguo Yiyao Gongye Zazhi published new progress about Protozoacides. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Feng, Wei-Xu; van der Lee, Arie; Legrand, Yves-Marie; Petit, Eddy; Dan, Dumitrescu; Su, Cheng-Yong; Barboiu, Mihail published the artcile< Adaptive Encapsulation of ω-Amino Acids and Their Guanidinium-Amide Congeners>, Category: esters-buliding-blocks, the main research area is omega amino acid guanidinium amide adaptive encapsulation.

The binding and the encapsulation of the 6-aminohexanoic acid (1) and 11-aminoundecanoic acid (2) are achieved in aqueous solution and in crystalline Pyrene-box cages. Unexpectedly, the amino-guanidinium AG+ and the amino acids 1 or 2 are reacting in aqueous solution in the absence and in the presence of Pyrene-box cages. The formation of an amide bond between a carboxylic acid and the amino-guanidine unit under mild acidic conditions in water without the use a coupling reagent is extremely interesting and unexpected. The resulted adducts AG1 and AG2 show adaptive binding behaviors and compressions.

Organic Letters published new progress about Amidation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mini, R.; Prabhu, V.; Vimaladevi, K.; Sowmiya, J.; Sibi, G. published the artcile< GC-MS analysis, phytochemical screening and biological activity of Bauhinia tomentosa (Linn.)>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is Bauhinia tomentosa phytochem screening GCMS analysis.

Present study aimed to evaluate the chem. composition and biol. activity for methanolic extract of Bauhinia tomentosa (Linn.) leaves grown in Western Ghats region of South India. The preliminary phytochem. screening tests revealed the presence of steroids, alkaloids, terpenoids, flavonoids, glycosides and phenolic compounds in the leaf extract A total of 19 compounds were identified through gas chromatog.-mass spectroscopy (GC-MS) anal. of methanolic extract of B. tomentosa. The major compounds identified were phytol (23.96%), n-hexadecanoic acid (11.62%), squalene (8.85%) and the minor compounds are trans-bis(2-methylpropyl)-4,6-dioxane(0.13%), dihydro-cis-α-copaene-8-ol (0.14%), tetradecanoic acid (0.81%), resp. Antibacterial activity of the extract showed the zone of inhibition 18 mm at 200 μg/mL against S. aureus, followed by 15 and 16 mm against S. anginosus, K. pneumoniae at 200 μg/mL, resp. Antioxidant activity of methanolic extract of B. tomentosa leaves showed the maximum IC50 value with 75.07% of scavenging activity at the concentration of 5 μg/mL.

Asian Journal of Chemistry published new progress about Acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

McCreath, S.; Boinard, P.; Boinard, E.; Gritter, P.; Liggat, J. J. published the artcile< High clarity polyurethane laminating adhesives based on poly(propylene glycol). Effect of hard segment on microphase morphology, haze and adhesion>, Application of C19H34O2, the main research area is polypropylene glycol diisocyanate polyurethane laminating adhesive haze adhesion morphol.

A series of polyurethanes were prepared, with poly(propylene glycol) used as soft-phase due to the high clarity of this polyol and absence of carbonyl functionality, which allows for hard-phase architecture to be resolved with greater resolution In total, eight adhesives were synthesized, each contained a different chain-extender formulation to gauge what influence hard-phase architecture had on laminate haze and peel strength. This was investigated using either 4,4-methylene di-Ph diisocyanate or isophorone diisocyanate as hard-phase with trimethylolpropane as the only chain-extender or by including one of the following sterically hindered diols: 2,2-diethyl-1,3-propane diol, 1,3-butane diol or 1,2-propane diol. DSC anal. showed that microphase morphol. was strongly influenced by the diisocyanate present, as shown by the degree of phase mixing being greater in methylene di-Ph diisocyanate based formulations when compared with isophorone diisocyanate based. This resulted in higher haze values being encountered for both polycarbonate and ethanolamine surface-treated polycarbonate laminates which contained methylene di-Ph diisocyanate based formulations when compared to isophorone diisocyanate based formulations, where all values were <1.5%. International Journal of Adhesion and Adhesives published new progress about Adhesion, physical. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dargo, Gyula; Nagy, Sandor; Kis, David; Bagi, Peter; Matravolgyi, Bela; Toth, Blanka; Huszthy, Peter; Drahos, Laszlo; Kupai, Jozsef published the artcile< Application of Proline-Derived (Thio)squaramide Organocatalysts in Asymmetric Diels-Alder and Conjugate Addition Reactions>, Related Products of 112-63-0, the main research area is hydroxyethyl nitro phenyl tetracyclic compound preparation enantioselective; anthracenyl acetaldehyde nitrostyrene Diels Alder reaction proline squaramide organocatalyst; hydroxynaphthoquinonyl keto ester preparation enantioselective; lawsone unsaturated keto ester conjugate addition proline squaramide organocatalyst.

The synthesis of chiral proline-derived squaramide and thiosquaramide organocatalysts I [X = O or S], which are capable of the dual activation in asym. reactions is reported. The (thio)squaramide moiety can form hydrogen bonds to activate the substrates and to stereocontrol the reaction, while the pyrrolidine unit can form enamines to activate carbonyl compounds via aminocatalysis. Comparing the performance of thiosquaramide to squaramide, the Diels-Alder reaction of (anthracen-9-yl)acetaldehyde and trans-beta-nitrostyrene (E)-RC6H4CH=CHNO2 [R = H, Br, OMe] was examined, which has been investigated in the literature using quantum chem. calculations Both squaramide and thiosquaramide gave excellent yields (up to 99%) and enantiomeric excess values (up to 98%). Moreover, their catalytic performance was compared in conjugate addition of lawsone to 2-oxo-4-phenyl-but-3-enoic acid Et ester.

Synthesis published new progress about Conjugate addition reaction catalysts, stereoselective. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics