Category: 112-63-0

Kim, Soyoun; Liu, Nan; Shestopalov, Alexander A. published the artcile< Contact Printing of Multilayered Thin Films with Shape Memory Polymers>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is shape memory polymer multilayer thin film transfer printing; adhesion modulation; donor substrate; shape memory polymer; thin-film printing; transfer printing.

This study describes a method for transfer printing microarrays of multilayered organic-inorganic thin films using shape memory printing stamps and microstructured donor substrates. By applying the films on the microstructured donor substrates during phys. vapor deposition and modulating the interfacial adhesion using a shape memory elastomer during printing, this method achieves (1) high lateral and feature-edge resolution and (2) high transfer efficiency from the donor to the receiver substrate. For demonstration, polyurethane-acrylate stamps and silicon/silicon oxide donor substrates were used in the large-area transfer printing of organic-inorganic thin-film stacks with micrometer lateral dimensions and sub-200 nm thickness.

ACS Nano published new progress about Adhesion, physical, interfacial. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Andersons, J.; Kirpluks, M.; Cabulis, P.; Kalnins, K.; Cabulis, U. published the artcile< Bio-based rigid high-density polyurethane foams as a structural thermal break material>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is polyurethane foam thermal break material.

Sustainable development of building industry implies increasing usage of green materials. With this aim and for the intended application as a structural thermal break material, rigid high-d. polyurethane foams have been manufactured using polyols derived from renewable resources – tall oil fatty acids. Thermal conductivity, compressive strength and stiffness of the foams of d. ranging from ca. 100 to 680 kg/m3 have been determined Comparison of the bio-based foams with reference foams derived from petrochem. resources demonstrated similar performance characteristics thus suggesting that bio-based foams can also serve as structural thermal break materials. Anal. models are shown to enable estimation of d. dependence of the thermal and mech. properties of foams using the resp. exptl. determined characteristics of the monolithic polyurethane polymer.

Construction and Building Materials published new progress about Compressive modulus. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Baudoux, Jerome; Cahard, Dominique published the artcile< Electrophilic fluorination with N-F reagents>, COA of Formula: C19H34O2, the main research area is review.

A review. The preparation and use of electrophilic fluorinating agents containing the N-F moiety to give a C-f bond is reviewed.

Organic Reactions (Hoboken, NJ, United States) published new progress about Organic synthesis. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mamedov, Shamkhal; Gadzhiev, F. R.; Rzaev, A. S. published the artcile< Ethers of glycols and their derivatives. LXVII. Synthesis of alkoxymethyl ethers of ο- and p-ethylbenzyl alc>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is .

By the alk. method there were synthesized several new alkoxy derivatives of the Me ether of ο- and p-ethylbenzyl alc. and the ο- and p-monoethylbenzyl ether of ethylene glycol. To a mixture of ο- and p-ethylbenzyl alc. (16.3 g.), 21.78 g. PhNMe2, and 50 ml. dry Et2O, 24.5 g. α-chloromethyl isoamyl ether was added dropwise, and the mixture stirred and heated 4.5 hrs. at 30-40° and worked up to give 19.32 g. mixture of isopentoxymethyl ethers of ο- and p-ethylbenzyl alc. b5 141-2°, n20D 1.4828, d20 0.9392. Similarly, 9 new alkoxy ether mixtures of general formula ο- and p-EtC6H4CH2OCH2OR were obtained (R, % yield, b.p., n20D, and d20 given): Me, 58.7, b19 127-8°, 1.4972, 0.9877; Et, 60.0, b5 106-7°, 1.4920, 0.9721; iso-Pr, 52.0, b5 113-14°, 1.4857, 0.9523; Pr, 50.0, b5 123-4°, 1.4872, 0.9568; iso-Bu, 59.0, b5 129-30°, 1.4820, 0.9455; Bu, 65.6 b5 135-6°, 1.4840, 0.9483; Am, 60, b5 146-7°, 1.4833, 0.9420; n-C6H13, 66.6, b5 157-8°, 1.4806, 0.9312; and n-C7H15, 59.8, b5 167-8°, 1.4800, 0.9279. To a mixture of 34 g. ethylbenzyl alc., 50 g. acrylonitrile, and 150 ml. dry C6H6 1.5 g. MeONa was added, and the mixture stirred 5 hrs. at 40-50° and worked up to yield 94% mixture (I) of β-cyanoethyl ethers of ο- and p-ethylbenzyl alc., b1 137-8°, n20D 1.5080, d20 1.0108. To 90 g. MeOH saturated with 18 g. HCl 19 g. I was added, and the mixture heated 2 hrs. and worked up to give 48% mixture of β-carbomethoxyethyl ethers of ο- and p-ethylbenzyl alc. (II), b. 133-4°, n20D 1.4970, d20 1.0397. A mixture of 250 ml. MeOH, 13 g. NaOH, 13 ml. H2O, 15 ml. Et2O, and 15.54 g. II was kept 24 hrs., CO2 passed in, and the precipitate worked up to give 67.4% mixture of β-(ο- and p-ethylbenzoxy)propionic acids, b3 178-80°, n20D 1.5185, d20 1.0815. Ethylbenzyl alc. (50 g.) was saturated with gaseous HCHO, dry HCl passed in at 5-10°, and the mixture worked up to give 57% mixture (III) of chloromethyl ο- and p-ethylbenzyl ethers, b2 97-8°, n20D 1.5210, d20 1.0803. To PhONa from 26.5 g. PhOH and 4.6 g. Na, 18.5 g. III was added dropwise, and the mixture stirred and heated 4 hrs. at 50-60° and worked up to give 53% mixture of phenoxymethyl ethers of ο-and p-ethylbenzyl alc., b1 153-5°, n20D 1.5502, d20 1.0530. A mixture of 23.2 g. ethylbenzyl chloride, 37 g. BuOH, and 20 g. powd. NaOH was heated 8 hrs. at 80-90° and worked up to give 76.4% mixture of Bu ο- and p-ethylbenzyl ethers, b. 102-3°, n20D 1.4830, d20 0.9078. Similarly the following ethers of the general formula ο- and p-EtC6H4CH2OR were obtained (R, % yield, b.p., n20D, and d20 given): Pr, 82, b4 92-3°, 1.4910, 0.9178; iso-Bu, 60.0, b4 96-7°, 1.4862, 0.9088; iso-Am, 79.0, b4 108-9°, 1.4834, 0.8998. Am, 80.9, b4 113-14°, 1.4860, 0.9028; n-C6H13, 69.7, b4 128-9°, 1.4855, 0.9008; and n-C7H15, 73.4, b4 141-2°, 1.4850, 0.8981. A mixture of 250 g. ethylene glycol and powdered 100 g. NaOH was heated until the NaOH was dissolved, 154.5 g. ethylbenzyl chloride added dropwise, and the mixture heated with stirring 5 hrs. at 120-30° and worked up to give 52% mixture (IV) of mono ο- and p-ethylbenzyl ethers of ethylene glycol, b2 151-3°, n20D 1.5150, d20 1.0280. A mixture of 18 g. IV, 80.4 g. Ac2O, 50 ml. dry C6H6, and 2 drops H2SO4 was stirred and heated 4 hrs. at 30-40° and worked up to give 65% IV acetate, b2 126-8°, n20D 1.4985, d20 1.0391. To a mixture of 18 g. IV, 18.15 g. PhNMe2, and 50 ml. dry Et2O 18.4 g. chloromethyl Bu ether was added dropwise and the mixture stirred and heated 3 hrs. at 30-40° and worked up to give 51% mixture of ο- and p-ethylbenzyl butoxymethyl ethers of ethylene glycol, b3 157-8°, n20D 1.4809, d20 0.9684. Similarly the following ο- and p-EtC6H4CH2OCH2CH2OCH2OR were obtained (R, % yield, b.p., n20D, and d20 given): Me, 58, b12 156-7°, 1.4912, 1.0105; Et, 54.6, b3 137-9°, 1.4906, 0.9967; iso-Pr, 62.6, b3 147-8°, 1.4827, 0.9772; Pr, 55.5, b3 153-5°, 1.4847, 0.9842. Bu, 71.0, b3 162-3°, 1.4831, 0.9698; iso-Am, 62.8, b3 169-70°, 1.4812, 0.9629, Am, 62.5, b3 175-6°, 1.4821, 0.9659; n-C6H13, 67.7, b3 185-6°, 1.4807, 0.9539; and n-C7H15, 54.0, b3 192-3°, 1.4805, 0.9530.

Azerbaidzhanskii Khimicheskii Zhurnal published new progress about Ethers. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Poole, Joshua; Jasbi, Paniz; Pascual, Agnes S.; North, Sean; Kwatra, Neha; Weissig, Volkmar; Gu, Haiwei; Bottiglieri, Teodoro; Jadavji, Nafisa M. published the artcile< Ischemic Stroke and Dietary Vitamin B12 Deficiency in Old-Aged Females: Impaired Motor Function, Increased Ischemic Damage Size, and Changed Metabolite Profiles in Brain and Cecum Tissue>, Synthetic Route of 112-63-0, the main research area is human ischemic stroke vitamin B12 deficiency brain cecum metabolite; aging; female; ischemic stroke; motor function; vitamin B12.

A vitamin B12 deficiency (vit. B12 def.) is common in the elderly, because of changes in metabolism Clin. studies have reported that a vit. B12 def. results in worse outcome after stroke, and the mechanisms through which a vit. B12 def. changes the brain requires further investigation. This study investigated the role of vit. B12 def. on stroke outcome and mechanisms using aged female mice. Eighteen-month-old females were put on a control or vit. B12 def. diet for 4 wk, after which an ischemic stroke was induced in the sensorimotor cortex. After damage, motor function was measured, the animals were euthanized, and tissues were collected for anal. Vit. B12 def. animals had increased levels of total homocysteine in plasma and liver, and choline levels were also increased in the liver. Vit. B12 def. animals had larger damage volume in brain tissue and more apoptosis. The cecum tissue pathway anal. showed dysfunction in B12 transport. The anal. of mitochondrial metabolomics in brain tissue showed reduced levels of metabolites involved in the TCA cycle in Vit. B12 def. animals. Motor function after stroke was impaired in vit. B12 def. animals. A dietary Vit. B12 def. impairs motor function through increased apoptosis and changes in mitochondrial metabolism in brain tissue.

Nutrients published new progress about Apoptosis. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Han, Fangbin; Lin, Songwen; Liu, Peng; Tao, Jing; Yi, Chongqin; Xu, Heng published the artcile< Synthesis and structure-activity relationships of PI3K/mTOR dual inhibitors from a series of 2-amino-4-methylpyrido[2,3-d]pyrimidine derivatives>, Application of C19H34O2, the main research area is pyridopyrimidine pyridine pyrimidine preparation anticancer antitumor agent; Anti-tumor activity; Dual inhibitor; Mammalian target of rapamycin; Phosphoinositide 3-kinase.

Inhibition of phosphoinositide 3-kinase (PI3K, phosphatidylinositol 3-kinase)/AKT/mammalian target of rapamycin (mTOR) signaling pathway by PI3K/mTOR dual inhibitors provides a promising new approach to the treatment of cancers. Target of rapamycin complex 1 (mTORC1) is a protein complex composed of TOR kinase/FRAP protein and proteins such as Raptor, GGβL, PRAS40 and Deptor (this complex is not associated with CREB-regulated transcription coactivator 1). Target of rapamycin complex 2 (mTORC2) is a protein complex composed of TOR kinase/FRAP protein and proteins such as Rictor, GβL and MAPKAP1 (this complex is not associated with CREB-regulated transcription coactivator 2). In this Letter, the authors have identified structurally novel and potent PI3K/mTOR dual inhibitors from a series of 2-amino-4-methylpyrido[2,3-d]pyrimidine derivatives Their synthesis and structure-activity relationships are reported. The synthesis of the target compounds was achieved by a coupling reaction of 6-bromo-4-methylpyrido[2,3-d]pyrimidin-2-amine with boronic acid reactants and/or aryl bromides. The title compounds thus formed included N-[5-(2-amino-4-methylpyrido[2,3-d]pyrimidin-6-yl)-2-methoxy-3-pyridinyl]-2,4-difluorobenzenesulfonamide and related substances.

Bioorganic & Medicinal Chemistry Letters published new progress about Amides Role: PAC (Pharmacological Activity), SPN (Synthetic Preparation), THU (Therapeutic Use), BIOL (Biological Study), PREP (Preparation), USES (Uses) (pyrido[2,3-d]pyrimidine derivatives). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fan, Xiaohui; Lin, Heng; Zhao, Jinjin; Mao, Yican; Zhang, Jiaxing; Zhang, Hui published the artcile< Activation of peroxymonosulfate by sewage sludge biochar-based catalyst for efficient removal of bisphenol A: Performance and mechanism>, HPLC of Formula: 112-63-0, the main research area is bisphenol peroxymonosulfate sewage sludge biochar catalytic oxidation wastewater treatment.

Activation of peroxymonosulfate (PMS) for organic-contaminated water remediation is a promising strategy. In this study, a sludge-derived biochar (SBC) was prepared as an efficient and low-cost metal-free catalyst to activate PMS for the abatement of bisphenol A (BPA) in water. The results demonstrate that BPA could be rapidly oxidized by the combination of SBC and PMS. Compared with the slight adsorption (8.1%) by SBC alone and limited direct oxidation (2.4%) by sole PMS, the removal efficiency of BPA was boosted to 94.5% within 60 min in the presence of both SBC and PMS. Active species participating in the rapid elimination of BPA were investigated via both chem. quenching experiment and ESR (EPR) technique. The results indicate that non-radical rather than radical process plays an important role in BPA abatement in the SBC/PMS system. The electron-transfer non-radical process was further verified by the open circuit potential test. It is proposed that PMS is bound to SBC to form a surface reactive complex (SBC-PMS*), which would abstract the electrons from the adsorbed BPA through the conductive carbon tunnel. The present work provides an alternative of controlling waste by waste.

Separation and Purification Technology published new progress about Binding energy. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Crotti, Simone; Di Iorio, Nicola; Artusi, Chiara; Mazzanti, Andrea; Righi, Paolo; Bencivenni, Giorgio published the artcile< Direct Access to Alkylideneoxindoles via Axially Enantioselective Knoevenagel Condensation>, Synthetic Route of 112-63-0, the main research area is cyclohexanone oxindole cinchona alkaloid amine catalyst enantioselective Knoevenagel condensation; cyclohexylidene oxindole stereoselective preparation.

The organocatalytic axially enantioselective Knoevenagel condensation between prochiral cyclohexanones and oxindoles is presented. The reaction, promoted by a primary amine, proceeded smoothly and furnished unprecedented examples of novel cyclohexylidene oxindoles displaying axial chirality, e.g., I.

Organic Letters published new progress about Cyclohexanones Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Subramanian, Yuvaraj; Oh, Woong; Choi, Woosung; Lee, Hayeon; Jeong, Mihee; Thangavel, Ranjith; Yoon, Won-Sub published the artcile< Optimizing high voltage Na3V2(PO4)2F3 cathode for achieving high rate sodium-ion batteries with long cycle life>, HPLC of Formula: 112-63-0, the main research area is graphene oxide sodium lithium ion battery soluble gel process.

Sodium-ion batteries have gained an intense attention as a promising alternate for Li-ion batteries due to their low cost, and abundant availability. To meet high energy d. requirements, developing a high voltage cathode with ultra-long cycle life is of great importance. Na3V2(PO4)2F3 (NVPF) features a high working voltage, fast sodium-ion diffusion channels, and small volume change during the cycling process. However, the practical performance of NVPF cathode is currently hindered by poor Na+ ion diffusion at high voltage, low cycle life, and limited rate behavior. Herein, we evaluate the effect of synthesis conditions in sol-gel technique, binders (PVDF, PAI and CMC), and electrolytes (ether, and ester based solvents) to overcome the diffusion limitation in high voltage NVPF cathode. Benefiting from the synergistic effect of CMC binder, and DEGME electrolyte, and reduced graphene oxide composite, NVPF effectively overcome the potential barrier during Na+ ion insertion/extraction at high voltage. NVPF with CMC binder and DEGDME electrolyte displayed a high Na+ ion diffusion kinetics, low cell resistance, and delivered an excellent electrochem. performance. The current study provides new insights for overcoming the kinetic barrier during sodium ion storage in high voltage cathode that could direct the research development towards high energy sodium-ion batteries.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Activation energy. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kyosiimire-Lugemwa, Jacqueline; Anywaine, Zacchaeus; Abaasa, Andrew; Levin, Jonathan; Gombe, Ben; Musinguzi, Kenneth; Kaleebu, Pontiano; Grosskurth, Heiner; Munderi, Paula; Pala, Pietro published the artcile< Effect of stopping cotrimoxazole preventive thrapy on microbial translocation and inflmmatory markers among human immunodefiiency virus-infected ugandan adults on antiretroviral thrapy: th COSTOP trial immunology substudy>, HPLC of Formula: 112-63-0, the main research area is cotrimoxazole lamivudine antibiotic antiretroviral agent adult inflammation HIV infection; ART; HIV-1; cotrimoxazole preventive therapy; immune activation; inflammation; microbial translocation.

Background. Cotrimoxazole preventive therapy (CPT) in human immunodeficiency virus (HIV) infection is a World Health Organization-recommended standard of care in resource-limited settings, but the mechanism of CPT’s beneficial effects is unclear. The COSTOP trial (ISRCTN44723643) evaluated the noninferiority of discontinuing CPT in stabilized patients on antiretroviral therapy. The COSTOP immunol. substudy was conducted on a subset of COSTOP participants randomized to continue CPT (n = 86) or discontinue CPT (placebo, n = 86) as daily treatment for 1 yr. Methods. We evaluated whether CPT reduces microbial translocation, indicated by the presence of bacterial lipopolysaccharide (LPS) and LPS control factors such as soluble CD14 (sCD14) and endotoxin core antibody (EndoCAb IgM [IgM]) in plasma. Intestinal barrier damage as indicated by plasma intestinal fatty acid binding protein (IFABP), T-cell activation, and the inflammatory markers C-reactive protein (CRP), interleukin 6 (IL-6), and tumor necrosis factor a (TNF-α) were also evaluated. Results. We found no significant change in markers of microbial translocation (LPS, IFABP, sCD14, and T-cell activation), with decreased EndoCAb IgM. There was significant increase in inflammation markers (CRP and IL-6) aftr stopping CPT compared to those who continued CPT. Conclusions. These results add to the evidence of immunol. benefits of CPT among HIV-infected populations in resourcelimited settings. However, no evidence of reducing microbial translocation was observed

Journal of Infectious Diseases published new progress about Adult, mammalian. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics