Category: 112-63-0

Da Silva, Marcio Jose; Chaves, Diego Morais; Teixeira, Milena Galdino; Oliveira Bruziquesi, Carlos Giovani published the artcile< Esterification of levulinic acid over Sn(II) exchanged Keggin heteropolyacid salts: An efficient route to obtain bioadditives>, Formula: C19H34O2, the main research area is esterification levulinate tin exchanged Keggin heteropolyacid bioadditive.

In this paper, we describe a process to add value to the biomass derivatives (i.e., levulinic acid), converting it to bioadditives over solid Sn(II) exchanged Keggin heteropolyacid salts. These solid catalysts are an attractive alternative to the traditional soluble and corrosive Bronsted acid catalysts. Among Sn(II) heteropoly salts, the Sn1.5PW12O40 was the most active and selective catalyst, achieving high conversions (ca. 90%) and selectivity (90-97%) for alkyl esters and angelica lactone, the main reaction products. The impacts of the main reaction parameters (i.e., catalyst load, temperature, and the molar ratio of alc. to acid) were investigated. The use of renewable raw material, and an efficient and recyclable catalyst are the main pos. features of this process. The Sn1.5PW12O40 catalyst was easily recovered and reused without loss activity.

Molecular Catalysis published new progress about Esterification. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rauter, Michael T.; Augustin, Matthias; Spitthoff, Lena; Svensson, Ann Mari published the artcile< Product formation during discharge: a combined modelling and experimental study for Li-O2 cathodes in LiTFSI/DMSO and LiTFSI/ TEGDME electrolytes>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is lithium bistrifluoromethanesulfonylimide dimethylsulfoxide tetraethylene glycol dimethyl ether electrolyte cathode.

Li-air or Li-O2 batteries are a promising energy storage technol. due to the potentially high energy d. However, significant challenges related to reversible charge/discharge of these cells need to be solved. The discharge reaction is generally agreed to proceed via two main routes, which may occur simultaneously. These are the surface mechanism, leading to Li2O2 product formation as surface films, or the solution mechanism, with solid particles formed in the pore structure of the cathode. A detailed understanding of the reaction mechanisms and the dynamic performance of the electrodes is key to further improvements. Here, we present a math. model for the discharge process, based on porous electrode theory, including effects of reactant transport and kinetic limitations, as well as the continuous change of properties due to the formation of reaction products via the solution mechanism and the surface mechanism. The model describes the dynamic change in the ratio of the surface and solution mechanism as a function of growth of film thickness, in line with recent findings. The model is able to predict the differences in exptl. obtained discharge curves between DMSO and tetra ethylene glycol di-Me ether solvents with 1M LiTFSI, with a min. of free parameters. The model parameters are based on phys. characterization of the materials and the electrodes, or determined by fitting to impedance spectra recorded during the discharge. The developed model and the methodol. will provide a powerful tool for optimization of such electrodes.

Journal of Applied Electrochemistry published new progress about Battery cathodes. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zheng, Liyou; Guo, Hongyan; Xie, Liangliang; Korma, Sameh A.; Jin, Jun; Jin, Qingzhe; Cacciotti, Ilaria published the artcile< Kinetic and thermodynamic studies of tocored thermal degradation in lipid systems with various degrees of unsaturation>, Reference of 112-63-0, the main research area is tocored thermal degradation lipid thermodn kinetics degree of unsaturation.

γ-Tocopherol-5,6-quinone (tocored) is a crucial minor component of edible oils. It has been certified to endow oils with an orange-red color and antioxidant activity. The tocored performance in lipid systems when exposed to heat should be investigated. Thus, the kinetics and thermodn. of tocored degradation in lipid systems with various degrees of unsaturation (Me palmitate, MP; Me oleate, MO; and Me linoleate, ML) were studied over a temperature range of 90-120°C. Tocored degradation probably followed zero-order kinetics, where the rate constant (3.22-24.59 and 23.18-299.2 mg kg-1 h-1 for MO and ML, resp.) significantly increased with increasing temperature (p < 0.05). The activation energy (Ea) values for the tocored degradation in MO and ML were 74.50 and 99.16 kJ mol-1, resp. Considering the thermodn. parameters (ΔH++>0, ΔS++<0, and ΔG++>0), the process both in MO and ML was endothermic and nonspontaneous. Above all, the kinetics and thermodn. data extend the knowledge on the tocored stability in oily systems, which is of vital importance for further oil industrial processing.

LWT–Food Science and Technology published new progress about Activation energy. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Melfi, Diego Trevisan; Carvalho dos Santos, Kallynca; Ramos, Luiz Pereira; Corazza, Marcos Lucio published the artcile< Supercritical CO2 as solvent for fatty acids esterification with ethanol catalyzed by Amberlyst-15>, SDS of cas: 112-63-0, the main research area is carbon dioxide Amberlyst esterification catalyst fatty acid ethanol.

This work reports on the esterification of fatty acids with ethanol using Amberlyst-15 in a scCO2-assisted system. A factorial design was carried out for the following process variables: temperature (70°C-110°C), ethanol to acid molar ratio (3:1 to 9:1) and catalyst to acid concentration (5-20 wt%), with a fixed amount of CO2 added to the reactor (28.62 g). The best reaction condition led to an 87% conversion at 110°C, 9:1, and 20 wt% in 15 min of reaction time. An exploratory kinetic study illustrates the effect of catalyst amount and molar ratio in isothermal kinetic curves. Also, a catalyst reuse study was performed. Addnl., different carboxylic acids and methanol, instead of ethanol, were evaluated as reagents. At all proposed systems, the addition of scCO2 increased the reaction conversion.

Journal of Supercritical Fluids published new progress about Esterification. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hamada, Taiji; Akahane, Toshiaki; Yokoyama, Seiya; Higa, Nayuta; Kirishima, Mari; Matsuo, Kei; Shimokawa, Michiko; Yoshimoto, Koji; Tanimoto, Akihide published the artcile< Oncogenic splice variant of PDGFRalpha in adult glioblastoma as therapeutic target for selective CDK4/6 inhibitors>, HPLC of Formula: 112-63-0, the main research area is CDK4 CDK6 inhibitor PDGFRalpha therapeutic target glioblastoma.

Understanding human genome alterations is necessary to optimize genome-based cancer therapeutics. However, some newly discovered mutations remain as variants of unknown significance (VUS). Here, the mutation c.1403A > G in exon 10 of the platelet-derived growth factor receptor-alpha (PDGFRA) gene, a VUS found in adult glioblastoma multiforme (GBM), was introduced in human embryonal kidney 293 T (HEK293T) cells using genome editing to investigate its potential oncogenic functions. Genome editing was performed using CRISPR/Cas9; the proliferation, drug sensitivity, and carcinogenic potential of genome-edited cells were investigated. We also investigated the mechanism underlying the observed phenotypes. Three GBM patients carrying the c.1403A > G mutation were studied to validate the in vitro results. The c.1403A > G mutation led to a splice variant (p.K455_N468delinsN) because of the generation of a 3′-acceptor splice site in exon 10. PDGFRA-mutated HEK293T cells exhibited a higher proliferative activity via PDGFRα and the cyclin-dependent kinase (CDK)4/CDK6-cyclin D1 signaling pathway in a ligand-independent manner. They showed higher sensitivity to multi-kinase, receptor tyrosine kinase, and CDK4/CDK6 inhibitors. Of the three GBM patients studied, two harbored the p.K455_N468delinsN splice variant. The splicing mutation c.1403A > G in PDGFRA is oncogenic in nature. Kinase inhibitors targeting PDGFRα and CDK4/CDK6 signaling should be evaluated for treating GBM patients harboring this mutation.

Scientific Reports published new progress about Cell morphology. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Prathap, K. Jagadeesh; Himaja, M.; Mali, Sunil V. published the artcile< 5-Amino-1-(5-chloropyridin-2-yl)-1H-pyrazole-4-carboxylamino acids as potent insecticidal agents>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is chlorohydrazinopyridine cyclocondensation ethoxymethylene cyanoacetate; pyridyl aminopyrazole acid preparation coupling amino acid ester; amino chloropyridinyl pyrazole carboxylamino acid preparation insecticidal antibacterial activity.

A new series of 5-amino-1-(5-chloropyridin-2-yl)-1H-pyrazole-4-carboxy amino acid derivatives were synthesized by using benzotriazol-1-yloxytris(dimethylamino) phosphonium hexafluorophosphate (BOP) as coupling reagent. The key intermediate 5-amino-1-(5-chloropyridin-2-yl)-1H-pyrazole-4-carboxylic acid was synthesized by condensation of 5-chloro-2-hydrazinopyridine with Et (ethoxymethylene)cyanoacetate followed by basic hydrolysis. The structures of the newly synthesized compounds were confirmed by IR, 1H NMR and Mass spectral anal. and were evaluated for their antimicrobial and insecticidal activities. Some of the synthesized compounds showed potent insecticidal activity and moderate antibacterial activity with respect to the standard drug.

Indian Journal of Heterocyclic Chemistry published new progress about Amino acid esters Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sui, Zhuyin; Chang, Zhaosen; Xu, Xiufeng; Li, Yulin; Zhu, Xiaoming; Zhao, Chen; Chen, Qi published the artcile< Direct growth of MnO2 on highly porous nitrogen-doped carbon nanowires for asymmetric supercapacitors>, Category: esters-buliding-blocks, the main research area is nitrogen dopant manganese dioxide carbon nanowire supercapacitor.

In this work, we present an effective route to develop composite electrodes consisting of highly porous nitrogen-doped carbon nanowires (PNCW) and manganese dioxide (MnO2), toward supercapacitor applications. The PNCW with hierarchically porous structure, prepared from polypyrrole nanowires, is used as a supporting substrate to deposit MnO2 based on a redox reaction between carbon and KMnO4. The morphol. of the deposited MnO2 can be tuned by simply changing solution pH. The as-prepared PNCW/MnO2 composites possess a porous macrostructure, which is beneficial for the transport and diffusion of ions and electrons. An aqueous asym. supercapacitor device has been assembled using PNCW and PNCW/MnO2 as electrodes, which presents a satisfied energy d. of 23.7 Wh kg-1 at 2000 W kg-1. The exptl. data prove the feasibility of using PNCW as a porous carbon substrate for the preparation of composite electrodes in the asym. supercapacitor.

Diamond and Related Materials published new progress about Density. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lopez, Rosana; Giorgi, M. Eugenia; Melgarejo, Linda Toro; Ducrey, Ivana; Balouz, Virginia; Gonzalez-Salas, Diego; Camara, Maria de los Milagros; Buscaglia, Carlos A.; de Lederkremer, Rosa M.; Marino, Carla published the artcile< Synthesis and characterization of α-D-Galp-(1→3)-β-D-Galp epitope-containing neoglycoconjugates for chagas disease serodiagnosis>, Reference of 112-63-0, the main research area is galactooligosaccharide epitope neoglycoconjugate preparation chagas disease serodiagnosis; Anti α-Gal; Neoglycoconjugate; Squarate conjugation method; Trypanosoma cruzi.

The immunodominant epitope α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-GlcNAc, expressed in the mucins of the infective trypomastigote stage of Trypanosoma cruzi has been proposed for multiple clin. applications, from serodiagnosis of protozoan caused diseases to xenotransplantation or cancer vaccinol. It was previously shown that the analog trisaccharide, with glucose in the reducing end instead of GlcNAc, was as efficient as the natural trisaccharide for recognition of chagasic antibodies. Here we describe the synthesis of α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-Glcp functionalized as the 6-aminohexyl glycoside and its conjugation to BSA using the squarate method. The conjugate of 6-aminohexyl α-D-Galp-(1→3)-β-D-Galp was also prepared Both neoglycoconjugates were recognized by serum samples of Trypanosoma cruzi-infected individuals and thus, are promising tools for the improvement of Chagas disease diagnostic applications.

Carbohydrate Research published new progress about Antibodies and Immunoglobulins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study) (chagasic). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pellegrino, Anna L.; Mezzalira, Claudia; Mazzer, Francesco; Cadi Tazi, Lila; Caneschi, Andrea; Gatteschi, Dante; Fragala, Ignazio L.; Speghini, Adolfo; Sorace, Lorenzo; Malandrino, Graziella published the artcile< Multifunctional ""Dy(hfa)3•glyme"" adducts: Synthesis and magnetic/luminescent behaviour>, Synthetic Route of 112-63-0, the main research area is multifunctional dysprosium hexafluoroacetylacetone glyme adduct preparation magnetic behavior luminescence.

Dysprosium β-diketonate compounds have recently gained a lot of attention due to their intriguing multifunctional properties. In this paper, a series of “”Dy(hfa)3•glyme”” adducts have been prepared through a one-pot reaction, in dichloromethane, from dysprosium(III) acetate monohydrate, hexafluoroacetylacetone and glyme [Hhfa = 1,1,1,5,5,5-hexafluoroacetylacetone, glyme = bis-(2-methoxyethyl)ether, 2,5,8,11-tetraoxadodecane, 2,5,8,11,14-pentaoxapentadecane]. Based on the length of the polyether, various coordination frameworks have been obtained going from a mononuclear [Dy(hfa)3•diglyme] adduct, to a polymeric chain system for the [Dy(hfa)3•2H2O•triglyme], and an ionic structure for the [Dy(hfa)2•tetraglyme]+[Dy(hfa)4]-. The relationship between the coordination framework in the “”Dy(hfa)3•glyme”” series and the magnetic and luminescent properties has been deeply investigated.

Inorganica Chimica Acta published new progress about Luminescence. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Huang, Muhua; Wu, Jinfeng; Dong, Jingcheng published the artcile< Modified BuShenYiQi formula alleviates experimental allergic asthma in mice by negative regulation of type 2 innate lymphoid cells and CD4+ type 9 helper T cells and the VIP-VPAC2 signalling pathway>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is BuShenYiQi formula ILC2 Th9 VIP VPAC2 signalling allergic asthma; Chinese medicine; airway inflammation; neuro-immune communication; type 2 immune response.

Modified BuShenYiQi formula (M-BYF) is derived from BuShenYiQi formula, used for the treatment of allergic asthma. The exact effect and mechanism of M-BYF on the improvement of asthma remain unclear. We investigated the mechanism underlying the therapeutic effect of M-BYF on allergic asthma. The asthma model was established in female BALB/c mice that were sensitized and challenged with ovalbumin (OVA). Mice in the treated groups were orally treated once a day with M-BYF (7, 14 and 28 g/kg/d) or dexamethasone before OVA challenge. Control and Model group received saline. Pathophysiol. abnormalities and percentages of lung type 2 innate lymphoid cells (ILC2s) and Th9 cells were measured. Expression levels of type 2 cytokines and transcription factors required for these cells function and differentiation were analyzed. Expression of vasoactive intestinal polypeptide (VIP)-VPAC2 signalling pathway-related proteins, and percentages of VIP expressing (VIP+) cells and VPAC2, CD90 co-expressing (VPAC2+CD90+) cells were detected. M-BYF alleviated airway hyperresponsiveness, inflammation, mucus hypersecretion and collagen deposition in asthmatic mice. M-BYF down-regulated percentages of ILC2s and Th9 cells with lower expression of GATA3, PU.1 and IRF4, reduced IL-5, IL-13, IL-9 and VIP production The decrease in the expression of VIP-VPAC2 signalling pathway and percentages of VIP+ cells, VPAC2+CD90+ cells were observed after M-BYF treatment. The LD50 value of M-BYF was higher than 90 g/kg. M-BYF alleviated exptl. asthma by neg. regulating ILC2s and Th9 cells and the VIP-VPAC2 signalling pathway. These findings provide the theor. basis for future research of M-BYF in asthma patient population.

Pharmaceutical Biology (Abingdon, United Kingdom) published new progress about Allergens Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics