Category: 112-63-0

Zhong, Liuyue; Hao, Yanxin; Zhang, Junheng; Wei, Fang; Li, Tingcheng; Miao, Menghe; Zhang, Daohong published the artcile< Closed-Loop Recyclable Fully Bio-Based Epoxy Vitrimers from Ferulic Acid-Derived Hyperbranched Epoxy Resin>, Quality Control of 112-63-0, the main research area is recyclable epoxy vitrimer ferulate hyperbranched resin.

Epoxy vitrimers with dynamic covalent networks enable reprocessing and recycling of epoxy thermosets. However, achieving high mech. performance remains a challenge. In this work, ferulic acid-based hyperbranched epoxy resin (FEHBP) was synthesized to produce closed-loop recyclable and catalyst-free epoxy vitrimers without compromising its thermal and mech. properties. The incorporation of FEHBP with a hyperbranched topol. structure improved the tensile strength, modulus, and toughness of epoxy vitrimers through an in situ reinforcing and toughening mechanism. The hydroxyls of FEHBP catalyzed the dynamic transesterification and accelerated the reprocessing of epoxy vitrimers. Thus, the obtained epoxy vitrimers demonstrated excellent weldability, malleability, and programmability. Epoxy vitrimers with 10 phr FEHBP exhibited high tensile strength (126.4 MPa), usable Tg (94°C), fast stress relaxation (a relaxation time of 45 s at 140°C) and a retention of tensile strength (above 88.3%) upon recycling. The degradation products were reused to produce new epoxy vitrimers under mild conditions with similar mech. properties and thermal stability as the original epoxy vitrimers, leading to closed-loop recyclable, fully bio-based epoxy vitrimers with potential for industrial applications.

Macromolecules (Washington, DC, United States) published new progress about Complex modulus, tan δ. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yuan, Tie-Jun; Xu, Xue-Han; Zhou, Nan; Yan, Ge; Gu, Ting-Wei; Peng, Li-Hua published the artcile< Phytochemicals as new therapeutic candidates simultaneously stimulate proliferation and counteract senescence of stem cells>, HPLC of Formula: 112-63-0, the main research area is phytochem antioxidant Wntbeta catenin signaling stem cell senescence; Molecular mechanism; Phytochemicals; Proliferation; Senescence; Stem cells.

Mesenchymal stem cells (MSCs) are promising candidates for regenerative therapy. However, the research and clin. application of MSCs are greatly hindered by the limited cells proliferation and replicative senescence. Therapeutic agents that can both enhance the proliferative ability and decrease the replicative senescence of MSCs are greatly needed, however, not been reported yet. Herein, for the first time, we identified 11 natural compounds from medicinal plants with both excellent proliferative and anti-senescence abilities in MSCs. The qPCR anal. indicated underlying mechanisms associated with fibroblast growth factor, transforming growth factor, Wnt/beta-catenin and leukemia-induced factor in proliferation; the reactive oxygen species production, mitochondrial dysfunction autophagy and proteostasis are involved in cells senescence-related mechanism. Phytochems. are demonstrated as novel therapeutic candidates with promising effects in both stimulating proliferation and retarding replicative senescence of stem cells with high safety.

Biomedicine & Pharmacotherapy published new progress about AMP-activated protein kinase activators. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

McDaid, Paul; Chen, Yonggang; Deng, Li published the artcile< A highly enantioselective and general conjugate addition of thiols to cyclic enones with an organic catalyst>, Category: esters-buliding-blocks, the main research area is asym conjugate addition thiol cycloalkenone bisdihydroquinidinylpyrimidine; cinchona alkaloid modified asym addition thiol cycloalkenone.

A bis(dihydroquinidinyl)pyrimidine derivative was used to catalyze the title reactions of benzenethiols, 2-naphthalenethiol, and PhCH2SH with cycloalkenones having 5- to 9-membered rings.

Angewandte Chemie, International Edition published new progress about Conjugate addition reaction catalysts, stereoselective. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Yingchun; Wu, Xiaoyi; Wang, Xinhui; Zeng, Yue; Liao, Yixuan; Zhang, Ruizhi; Zhai, Fuqiang; Zeng, Zhongliang published the artcile< Grey relational analysis combined with network pharmacology to identify antioxidant components and uncover its mechanism from Moutan Cortex>, COA of Formula: C19H34O2, the main research area is antioxidant gray relational analysis network pharmacol paeonol paeonia suffruticosa; antioxidant; grey relational analysis; network pharmacology; paeonia suffruticosa andr; paeonol.

The present study determines the potential antioxidants in Moutan Cortex (MC) and predicts its targets of anti-oxidative activities. The quant. anal. and the free radical scavenging assays were conducted to detect the main components in MC and assess its anti-oxidant activities. The gray relational anal. and the network pharmacol. approach were employed to predict its key components and targets of anti-oxidant activities. Six main constitutes in MCs were quantified by high performance liquid chromatog. (HPLC) and its anti-oxidant activities were evaluated by DPPH and ABTS free radical scavenging methods. Then gray relational anal. was employed to predict the key components acting on anti-oxidative activity based on the chem-bio results. The predicted components and its mechanisms on anti-oxidation were uncovered by network pharmacol. approach and cell test, resp. The content of paeonol and paeoniflorin accounts for more than 80% the whole content of detected components. However, the two main ingredients showed a great variety among MCs. The antioxidant capacities of MCs also showed a great discrepancy based on DPPH and ABTS methods. The key components acting on anti-oxidation were identified to be paeonol, gallic acid and benzoylpaeoniflorin, and their potential therapeutic targets were predicted and verified, resp. The present results reveal that MC has a significant antioxidant activity and the compounds of paeonol, gallic acid and benzoylpaeoniflorin could be considered as the promising antioxidant candidates with the property of suppressing oxidative stress and apoptosis.

Frontiers in Pharmacology published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fazal, M. A.; Rubaiee, Saeed; Al-Zahrani, A.; Ghazali, Sami published the artcile< Biodiesel degradation mechanism upon exposure of metal surfaces: A study on biodiesel sustainability>, Reference of 112-63-0, the main research area is copper biodiesel sustainability degradation.

The increased demand and price of petroleum diesel along with its limited reservation and emitted harmful substances have made the world confronted. Biodiesel as an alternative to petroleum diesel offers immediate potential to meet these concerns. It provides several tech. benefits over diesel such as reduced emission, high flash point, and improved cetane number However, the oxidative nature of biodiesel is found to be one of the major problems which limits its com. usage and sustainability. Mol. reactions in biodiesel and their susceptibility to oxidation are important to understand but only limited information is available in this regard. The present study aims to investigate the biodiesel mol. changes upon exposure of metal surface. The tests were conducted by immersing copper coupons in palm biodiesel at ambient temperature (25-27°C) for various immersion time, viz., 200 h, 600 h, 1200 h, 2880 h. D., total acid number and composition of biodiesel before and after immersion tests were determined by d. meter, TAN analyzer and gas chromatog. mass spectroscopy anal. Date obtained from different tests are analyzed and compared to explore the possible degradation mechanism of biodiesel mols. Results show that the key components of biodiesel include Me stearate (9.94%), palmitate (38.64%), oleate (34.29%) and linoleate (6.92%). Upon exposure of copper for 2880 h, the concentrations of these mols. are changed to 10.14%, 33.78%, 31.34% and 1.09% resp. Such changes in composition cause alteration in fuel properties and thus, hinders its sustainability. The possible reaction mechanisms have been discussed in detail with the help of obtained data and relevant literatures.

Fuel published new progress about Biodiesel fuel. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cruz, Luis M.; Basilio, Nuno M.; de Freitas, Victor A.; Lima, Joao C.; Pina, Fernando J. published the artcile< Extending the Study of the 6,8 Rearrangement in Flavylium Compounds to Higher pH Values with Interconversion between 6-Bromo and 8-Bromo-apigeninidin>, Category: esters-buliding-blocks, the main research area is rearrangement flavylium ompound Bromo apigeninidin hemiketal; 6,8 flavylium rearrangement; 6-bromo-apigeninidin; 8-bromo-apigeninidin; UV/Vis; anthocyanins.

The rearrangement between isomers 6- and 8-bromo-apigeninidin (6 and 8) was studied by pH jumps using stopped flow, UV/Vis, NMR, and HPLC anal. The system constitutes a pH-dependent network of chem. reactions involving up to 18 different species. The dynamic network is equivalent to a single diprotic acid exhibiting two pKas, 2.55 and 5.4. Similar to other flavylium derivatives, the mole fraction of the species hemiketal and cis-chalcone in both multistate isomers are negligible at the equilibrium At pH 1, the pure isomers are slowly converted in a mixture containing about 50 % of isomers 6 and 8, while at pH 4, the system evolves to mixture of 10 % trans-chalcone and 90 % of quinoidal bases. A series of pH jumps from pure isomer 6 at pH 1 to pH 6 and back to pH 1 leads to the same initial absorption spectra of the pure isomer 6. The same occurs for pure isomer 8, showing the lack of communication between the cis-chalcones, at least in the time scale of few minutes. A pH jump from the equilibrated mixture of the isomers at pH 1.0 to 5.8 permits to follow a very slow isomerization.

ChemistryOpen published new progress about Absorption. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Jiarong; Guo, Mingyu published the artcile< Thermo-responsive, mechanically robust and 3D printable supramolecular hydrogels>, Reference of 112-63-0, the main research area is three dimensional supramol hydrogel.

In this work, poly(N-isopropylacrylamide) (PNIPAm) grafted and multi-urea linkage segmented linear polyurethane-urea (PUU) copolymers were synthesized using α-dihydroxyl terminated PNIPAm as a chain extender and water as an indirect chain extender, resp. A series of PUU supramol. hydrogels were then easily obtained by solution casting and then water swelling of these PUU copolymers. These PUU supramol. hydrogels show not only thermo-responsive surface wettability, but also robust mech. performance with tensile strength and elongation at break of 0.2-2.9 MPa and 1100-3000%, resp., at 37°C. In addition, temperature responsive and mech. strong 3D hydrogel scaffolds were also developed by a direct-write 3D printing technique using a methanol solution of the PUU copolymer as the ink. These supramol. hydrogels are expected to be used as functional biomaterials, especially as elastic substrates for cell sheet cultures under dynamic mech. stimulation.

Polymer Chemistry published new progress about Contact angle. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Marfat, Anthony; Carta, Michael P. published the artcile< Oxidation of indoles with pyridinium bromide perbromide. A simple and efficient synthesis of 7-azaoxindoles>, Quality Control of 112-63-0, the main research area is indole oxidation pyridinium bromide perbromide; azaindole oxidation pyridinium bromide perbromide; oxindole dibromo; azaoxindole.

Oxidation of indoles I (X = CH, R = H, Cl, NO2, F, cyano; X = N, R = H) by pyridinium bromide perbromide gave 20-88% dibromooxindoles II (R1 = Br), which on reduction gave oxindoles II (R1 = H).

Tetrahedron Letters published new progress about Oxidation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Zhi-wen; Pan, Rui-long; Wu, Jie-ying published the artcile< Synthesis and optical properties of a novel quinoline derivative>, COA of Formula: C19H34O2, the main research area is optical property quinoline derivative synthesis.

A novel quinoline derivative, 8-[N-{4-[4-(di-Ph amine) styryl] phenyl}] acetyl amino oxyl quinoline (1), was synthesized from triphenylamine and 8-hydroxylquinoline by formylation, Wittig-hornor reaction, substitution reaction and so on. The structure was characterized by 1H NMR, 13C NMR, IR and ESI-MS. The optical properties of 1 were investigated by UV-Vis and fluorescence spectroscopies. The results showed that λmax of 1 is 300 nm and 375 nm. The maximum peak of 1 was at 450 nm under excitation wavelengths of 375 nm in EtOH.

Hecheng Huaxue published new progress about Crystallinity. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Hongling; Wang, Yuhuang; Chen, Xingkuan; Mou, Chengli; Yu, Shuyan; Chai, Huifang; Jin, Zhichao; Chi, Yonggui Robin published the artcile< Chiral Nitroarenes as Enantioselective Single-Electron-Transfer Oxidants for Carbene-Catalyzed Radical Reactions>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is carbene catalyzed radical hydroxylation enal; chiral nitroarene enantioselective single electron transfer oxidant.

A new class of chiral oxidants is developed. These readily accessible oxidants contain a nitro group for oxidation and a chiral sulfonamide moiety for stereoselectivity control. The chiral information from the oxidants can effectively transfer to the substrates in carbene-catalyzed β-hydroxylation of enals via single-electron-transfer radical processes. We expect these oxidants to find unique applications in other asym. oxidations and oxygen-atom-transferring reactions.

Organic Letters published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics