Category: 112-63-0

Pliss, E. M.; Soloviev, M. E.; Loshadkin, D. V.; Molodochkina, S. V.; Kasaikina, O. T. published the artcile< Kinetic model of polyunsaturated fatty acids oxidation in micelles>, Related Products of 112-63-0, the main research area is fatty acid micelle oxidation kinetics mechanism; Kinetic modeling; Micelles; Oxidation of PUFAs; Radical intermediates.

A kinetic model of polyunsaturated fatty acids (PUFAs) radical chain oxidation in micelles is presented, taking into account the diffusion of active intermediates between aqueous and organic phases, and its effect on the detailed mechanism of the process. The model made it possible to indirectly involve the structural changes of micelles and their kinetic characteristics by varying the actual values of the reactions rate constants The modeling results are in good agreement with exptl. data for the oxidation of Me linoleate and linoleic acid.

Chemistry and Physics of Lipids published new progress about Chain reaction mechanism (oxidation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bezkrovnaya, O. N.; Pritula, I. M.; Puzikov, V. M.; Maslov, V. V.; Kolybaeva, M. I.; Gurkalenko, Yu. A.; Vovk, O. M.; Lopin, A. V.; Plaksii, A. G. published the artcile< SiO2 based active media with incorporated molecules of rhodamines and pyrenetetrasulfonic acid>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is rhodamine pyrenetetrasulfonic acid tetrasodium salt silica medium optical property.

SiO2-matrixes with incorporated mols. of fluorescent dyes are synthesized by a sol-gel method. Transparency of the samples depends on the molar ratio of water and formamide. The influence of silica gel matrix on the appearance of excimer fluorescence of 1, 3, 6, 8-pyrenetetrasulfonic acid tetra-sodium salt is studied. The lasing-action threshold of SiO2-matrix with rhodamine 6G is determined The lasing peak of rhodamine 6G in SiO2-matrix is 575.7 nm; the half-width equals 2.2 nm.

Nanosistemi, Nanomateriali, Nanotekhnologii published new progress about Annealing. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kourakis, Stephanie; Timpani, Cara A.; de Haan, Judy B.; Gueven, Nuri; Fischer, Dirk; Rybalka, Emma published the artcile< Dimethyl fumarate and its esters: a drug with broad clinical utility?>, Quality Control of 112-63-0, the main research area is review dimethyl fumarate ester antioxidative antiinflammatory inflammation oxidative stress; Nrf2; clinical application; dimethyl fumarate; disease; fumaric acid esters; inflammation; oxidative stress.

A review. Fumaric acid esters (FAEs) are small mols. with anti-oxidative, anti-inflammatory and immune-modulating effects. Di-Me fumarate (DMF) is the best characterized FAE and is approved and registered for the treatment of psoriasis and Relapsing-Remitting Multiple Sclerosis (RRMS). Psoriasis and RRMS share an immune-mediated etiol., driven by severe inflammation and oxidative stress. DMF, as well as monomethyl fumarate and diroximel fumarate, are commonly prescribed first-line agents with favorable safety and efficacy profiles. The potential benefits of FAEs against other diseases that appear pathogenically different but share the pathologies of oxidative stress and inflammation are currently investigated.

Pharmaceuticals published new progress about Anti-inflammatory agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Voelter, Wolfgang; Kuhfittig, Gisela; Schneider, Gottfried; Bayer, Ernst published the artcile< Conformational analysis of aldoses by means of circular dichroism>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is circular dichroism spectra sugar conformation; sugar conformation CD spectra; spectra CD sugar conformation; conformation sugar CD spectra; Cotton effect sugar conformation.

Molybdate complexes of sugars with their first 3 C atoms in axial/equatorial/axial cis position showed 3 or 4 Cotton effects between 350-220 nm. When the OH groups at C-2 and C-3 were trans, only 2 Cotton effects of opposite signs were found in the same region. Molybdate complexes of D-altrose, 6-O-methyl-D-glucose, D-allose, D-gulose, and D-talose showed the expected CD bands.

Justus Liebigs Annalen der Chemie published new progress about Conformation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ma, Xiantao; Xu, Qing; Li, Huan; Su, Chenliang; Yu, Lei; Zhang, Xu; Cao, Hongen; Han, Li-Biao published the artcile< Alcohol-based Michaelis-Arbuzov reaction: an efficient and environmentally-benign method for C-P(O) bond formation>, Electric Literature of 112-63-0, the main research area is Michaelis Arbuzov green alc carbon phosphorus bond formation; phosphonate phosphinate phosphine oxide preparation.

The famous Michaelis-Arbuzov reaction is extensively used both in the laboratory and industry to manufacture tons of widely-used organophosphoryl compounds every year. However, this method and the modified Michaelis-Arbuzov reactions developed recently still have some limitations. We now report a new alc.-version of the Michaelis-Arbuzov reaction that can provide an efficient and environmentally-benign method to address the problems of the known Michaelis-Arbuzov reactions. That is, a wide range of alcs. can readily react with phosphites, phosphonites, and phosphinites to give all the three kinds of phosphoryl compounds (phosphonates, phosphinates, and phosphine oxides) using an n-Bu4NI-catalyzed efficient C-P(O) bond formation reaction. This general method can also be easily scaled up and used for further synthetic transformations in one pot.

Green Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tan, Zhangbin; Jiang, Xiaoli; Zhou, Wenyi; Deng, Bo; Cai, Min; Deng, Suihui; Xu, Youcai; Ding, Wenjun; Chen, Guanghong; Chen, Ruixue; Zhang, Shuangwei; Zhou, Yingchun; Liu, Bin; Zhang, Jingzhi published the artcile< Taohong siwu decoction attenuates myocardial fibrosis by inhibiting fibrosis proliferation and collagen deposition via TGFBR1 signaling pathway>, Reference of 112-63-0, the main research area is myocardial fibrosis proliferation TGFBR1 signaling pathway; Cell proliferation; Collagen deposition; Myocardial fibrosis after myocardial infarction; TGFBR1; Taohong siwu decoction.

The purpose of current study was to explore the potential mechanism action and anti-myocardial fibrosis effects of treatment with THSWD in vivo and in vitro. Mouse underwent ligation of coronary artery to induce MI and divided equally into the sham group, model group and THSWD treatment groups. After 4 wk, the effects of THSWD treatment on cardiac function were estimated by echocardiog. HE staining was used to detect the pathol. changes and Masson trichrome staining was used to estimate tissue fibrosis. To further explore the regulatory mol. mechanisms of THSWD, transcriptome anal. was performed. Treatment with THSWD significantly decreased myocardial fibrosis and recovered cardiac function in the post-MI mouse. The transcriptomics data imply that the TGF-β pathway might be a target in the anti-fibrosis effect of THSWD. THSWD inhibits TGF-β1-induced proliferation of primary cardiac fibroblasts. THSWD decreased collagen expression and TGFBR1 and Smad2/3 phosphorylation. Moreover, the inhibitory effect of THSWD on CFs proliferation and collagen deposition, as well as TGFBR1 signaling pathway-associated proteins expression was partially abrogated by overexpression of TGFBR1. Collectively, the results implicate that THSWD attenuates myocardial fibrosis by inhibiting fibrosis proliferation and collagen deposition via inhibiting TGFBR1, and might be a potential therapeutic agent for treatment of myocardial fibrosis post-MI.

Journal of Ethnopharmacology published new progress about Adenoviral vectors. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Na Rungsi, Artita; Truong, Thuong Hai; Thunyaratchatanon, Chachchaya; Luengnaruemitchai, Apanee; Chollacoop, Nuwong; Chen, Shih-Yuan; Mochizuki, Takehisa; Takagi, Hideyuki; Yoshimura, Yuji published the artcile< Tuning the porosity of sulfur-resistant Pd-Pt/MCM-41 bimetallic catalysts for partial hydrogenation of soybean oil-derived biodiesel>, Electric Literature of 112-63-0, the main research area is sulfur palladium platinum MCM41 soybean oil partial hydrogenation catalyst.

Partial hydrogenation of soybean oil-derived fatty acid Me esters was studied using MCM-41 mesoporous silica-supported Pd-Pt bimetallic catalysts with tunable porosity under mild reaction conditions (100°C, 0.4 MPa H2, 4 h). This process produced partially hydrogenated fatty acid Me esters (H-FAME) as a new type of high-quality biodiesel fuel enriched in monounsaturated fatty acid Me esters (mono-FAME), which is a potential source for formulating high blends of biodiesel fuel with petrodiesel. MCM-41 supports with various structural properties and morphologies were synthesized by self-assembly with different amounts of ammonia solution as a mineralizing agent. Bimetallic Pd-Pt nanoparticles with a Pd/Pt at. ratio of 4 were stepwise impregnated on three MCM-41 supports, resulting in a series of Pd-Pt/MCM-41 bimetallic catalysts with tunable porosity (0.89-1.79 cm3 g-1), average pore size (3.2-8.5 nm), and particle size (0.12-0.62μm). The Pd-Pt/MCM-41 catalyst prepared with the least amount of ammonia produced the best partial hydrogenation conversion of polyunsaturated FAME into mono-FAME, ascribed to nano-aggregation resulting in a dual-pore system containing large pores for fast mol. diffusion; a high turnover frequency (1920 h-1), larger k1 rate constant (0.60 gcat-1h-1), and smaller k2 rate constant (0.37 gcat-1h-1) were obtained. Furthermore, this Pd-Pt/MCM-41 catalyst exhibited excellent sulfur resistance in the synthesis of H-FAME, even though the feedstocks contained approx. 5 ppm of sulfur contaminates. These results demonstrate that the sulfur-resistant Pd-Pt/MCM-41 bimetallic catalysts with stable and dual pore system are beneficial for obtaining higher quality BDF to reduce our reliance on fossil fuels.

Fuel published new progress about Biodiesel fuel. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Timelthaler, Daniel; Topf, Christoph published the artcile< Heterogeneous Hydrogenation of Quinoline Derivatives Effected by a Granular Cobalt Catalyst>, HPLC of Formula: 112-63-0, the main research area is tetrahydroquinoline preparation green chem; quinoline hydrogenation cobalt catalyst.

A convenient method for the pressure hydrogenation of quinolines I (R1 = 6-F, 5-Cl, 6-Br, etc.; R2 = 2-Me, 3-Me, 3-OMe, 2-Me, 2-phenyl) in aqueous solution by using a particulate cobalt-based catalyst that is prepared in situ from simple Co(OAc)2·4H2O through reduction with abundant zinc powder has been described. This catalytic protocol permits a brisk and atom-efficient access to a variety of 1,2,3,4-tetrahydroquinolines II thereby relying solely on easy-to-handle reagents that are all readily obtained from com. sources. Both the reaction setup assembly and the autoclave charging procedure are conducted on the bench outside an inert-gas-operated containment system, thus rendering the overall synthesis time-saving and operationally very simple.

Synthesis published new progress about Green chemistry. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tiwari, Gargi; Sharma, Dipendra; Singh, N. B. published the artcile< Electronic structure and molecular docking studies of an anti-HIV drug: stavudine>, HPLC of Formula: 112-63-0, the main research area is stavudine anti HIV electronic structure mol docking.

For anti HIV activity, Stavudine (or D4T or Zerit) is an important nucleoside reverse transcriptase inhibitor (NRTI). Mol. geometry of this compound has been optimized by DFT B3LYP/6-31G (d,p) method using Gaussian 03 software package. In order to examine global reactivity descriptors of the drug mol., Frontier orbital anal. has been carried out. Using mol. docking inhibition activity of the drug against HIV-1 reverse transcriptase (6AN2) has been investigated. Attempts have been made to elucidate the chem. and biol. properties of the drug.

Journal of Scientific & Industrial Research published new progress about Anti-HIV agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ma, Jun-An; Cahard, Dominique published the artcile< Screening of chiral catalysts for enantioselective electrophilic fluorination of β-keto esters>, Category: esters-buliding-blocks, the main research area is stereoselective fluorination keto ester chiral ligand.

A variety of oxygen- and nitrogen-containing chiral ligands in combination with various metals have been screened in the enantioselective electrophilic fluorination of tert.-Bu 2-oxocyclopentanecarboxylate. This study involved the use of readily available substrate, chiral ligands and electrophilic fluorinating agents. In particular, heterobimetallic Al-Li-BINOL complex led to enantiomerically enriched α-fluoro-β-keto ester in high yields and enantioselectivities ≤ 67% ee. A comparison with previously reported chiral ligands is provided.

Journal of Fluorine Chemistry published new progress about Chiral ligands Role: CAT (Catalyst Use), USES (Uses). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics