Category: 112-63-0

Pandiangan, K. D.; Simanjuntak, W.; Alista, D. I.; Ilim, I. published the artcile< The effect of NiO loads on catalytic activity of NiO/ZSM-5 for transesterification of rubber seed oil>, COA of Formula: C19H34O2, the main research area is transesterification rubber seed oil nickel oxide ZSM5.

In this investigation, a series of NiO/ZSM-5 with different NiO loads were produced and applied to catalyze transesterification of rubber seed oil (RSO) with methanol. ZSM-5 was prepared using hydrothermal technique from rice husk silica (RHS) and Al(OH)3 without using a template and then impregnated with Ni(NO3)2 solution of different concentrations followed by 6 h calcination at 600°C. Characterizations were performed with Fourier transform IR (FTIR) spectroscopy, x-ray diffraction (XRD), scanning electron microscope (SEM), and x-ray fluorescence (XRF). The establishment of ZSM-5 was confirmed by XRD and SEM, and NiO/ZSM-5 by XRD, SEM, and XRF. Catalytic activity tests demonstrate a significant enhancement of performance of NiO/ZSM-5 compared to that of ZSM-5 without NiO. Practically complete conversion of RSO into Me esters was achieved with the use of NiO/ZSM-5 catalysts prepared using 5, 10, and 15% nickel solution; however, decreases with the use of 20% nickel solution In this respect, it can be concluded that a 5% nickel solution is sufficient to produce NiO/ZSM-5 enabling complete conversion of RSO into biodiesel, suggesting that NiO/ZSM-5 is a prospective heterogeneous catalyst for biodiesel production

Rasayan Journal of Chemistry published new progress about Biodiesel fuel. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Seidel, F.; Thier, W.; Uber, A.; Dittmer, J. published the artcile< The formation of ""triacetylacetic ester."" II>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is .

It had been reported that in the preparation of Ac2CHCO2Et according to Claissen there is also formed Ac3CCO2Et (I), since the reaction product gave with N2H4 a product (II) assumed to be Et 3,5-dimethylpyrazole-4-acetyl-4-carboxylate (III). v. Auwers (C. A. 27, 62) doubts the existence of I and the correctness of the structure III for II. It has now been found that II changes above its m. p. into β-(5-hydroxy-3-methyl-4-pyrazolyl)crotonolactone (IV), and hence II is not a condensation product of I with N2H4 but Et β-(5-hydroxy-3-methyl-4-pyrazolyl)crotonate (V). The N2H4 first deacetylates the Ac2CHCO2Et in the reaction mixture, forming AcCH2CO2Et and AcNHNH2 (the greater part of the N2H4 thus escaping further reaction), and the unchanged N2H4 condenses with a part of the AcCH2CO2Et to 3-methyl-5-pyrazolone which combines with the rest of the AcCH2CO2Et to form V with loss of water. All attempts to prepare the true III (which is isomeric with IV) were unsuccessful, but they yielded hitherto unknown intermediate products which not only contributed to the knowledge of the reactivity of the pyrazoles and pyrazolones but also helped to establish the structure of V with certainty. Et 3,5-dimethylpyrazolone-4-carboxylate (VI), from Ac2CHCO2Et (reacting in the mono-enolic form, of which the equilibrium mixture contains 91.8%) and N2H4, gives with AcCl the 1-Ac derivative (VII) which, after saponification, is decarboxylated to 1-acetyl-3,5-dimethylpyrazole (VIII). The structure of VIII is established: (1) by condensing Ac2CH2 (76% enol) with N2H4 to 3,5-dimethylpyrazole (IX) and acetylating IX to VIII with AcCl in pyridine; (2) by synthesis of VIII from Ac2CH2 and NH2NHAc. Direct replacement of the 4-H atom on the pyrazole nucleus by acyl is not possible; to obtain 3,5-dimethyl-4-acetylpyrazole (X), CHAc3 (88.3% enol at equilibrium) must be condensed with N2H4. It reacts with AcCl to form the 1,4-di-Ac derivative (XI). It was hoped that IV (or the free acid) might be obtained by saponifying isodehydracetic ester to HO2CCH:CMeC(CO2Et):C(OH)Me and condensing the latter with N2H4, but the product was always only 3-methyl-5-pyrazolone, the isodehydracetic ester evidently breaking down into AcCH2CO2Et under even the mildest conditions. Definite proof that 3-methyl-5-pyrazolone reacts at the 4-position with AcCH2CO2Et to form V was obtained indirectly. Reaction through the NH group is excluded, for 3,4,4-trimethyl-5-pyrazolone does not react with AcCH2CO2Et but 1-phenyl-3-methylpyrazolone does, yielding Et (β-5-hydroxy-1-phenyl-3-methyl-4-pyrazolyl)crotonate (XII), which splits off EtOH at 165° to form the lactone (XIII). Further evidence that the NH group is not involved in the condensation is afforded by the fact that IV forms a Bz derivative V, obtained in 24 g. yield from a charge of 638 g. AcCH2CO2Et, 88.6 g. Na and 600 g. AcCl, m. 188°, is also obtained readily by Wolff’s method (Ber. 38, 3038(1905)); it is stable toward boiling MeOH and alc. NH3 but with PhNHNH2 and concentrated KOH gives 3-methyl-5-pyrazolone. IV, m. 246°. Free acid, from IV and 10% NaOH at 15-20°, m. 154° (decomposition), regenerates IV on heating in vacuo at 15-20° or in hot alc. VII (6.2 g. from 7.0 g. VI), m. 69°; free acid, similarly obtained (6.0 g.) from the free acid (5.0 g.) of VI, m. 164°. VIII, b12 70°, b23 84°. 1-Bz analog, b12 158°. X, needles with 1 H2O, m. 121° (decomposition) and (anhydrous) 128°. XI, m. 50°. XII, m. 88°. XIII, light yellow, m. 132°. 1-Bz derivative of VI, m. 181°.

Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bubenchikova, V. M.; Popova, T. P.; Litvinenko, V. I. published the artcile< The flavonoids of medicinal dandelions>, SDS of cas: 112-63-0, the main research area is dandelion flavonoid luteolin.

Medicinal dandelion contained 1.35% flavonoids, the major compound being luteolin comprising 0.8% of the crude drug.

Farmatsevtichnii Zhurnal (Kiev) published new progress about Flavonoids Role: BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Viswanatha, T.; Bayer, E.; Wilchek, Meir published the artcile< Reversibility of the affinity-labeled biotin transport system in yeast cells>, Formula: C19H34O2, the main research area is biotin transport Saccharomyces.

Transport of biotin by Saccharomyces cerevisiae is inhibited by biotynyl p-nitrophenyl ester. Conversion of the inhibited cells to spheroplasts or simple treatment with thiols results in a total restoration of vitamin transport. Biotinyl p-nitrophenyl ester-induced inhibition is not due to an intracellular accumulation of the vitamin and consequent regulation, but appears to be due to specific labeling of the transport system.

Biochimica et Biophysica Acta, Biomembranes published new progress about Biological transport. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sun, Zhonghe; Wang, Mu; Li, Zhi; Choi, Bonnie; Mulder, Roger J.; Feng, Anchao; Moad, Graeme; Thang, San H. published the artcile< Versatile Approach for Preparing PVC-Based Mikto-Arm Star Additives Based on RAFT Polymerization>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is versatile preparing PVC mikto arm star RAFT polymerization.

A versatile approach to the synthesis of migration-resistant poly(vinyl chloride) (PVC) additives is described and a preliminary assessment of their properties is presented. The process involves the synthesis of AB2 3-mikto-arm stars, star-[PVC-block-(polyB);(polyB)2] or star-[PVC;(polyB)2], that contain a reversible addition-fragmentation chain transfer (RAFT)-synthesized PVC segment, to provide compatibility with PVC and good migration resistance, and multiple RAFT-synthesized segments (polyB), where polyB is based on more activated monomer (a styrene or a methacrylate) that contains the functionality required to impart the desired additive properties. The approach to PVC-based stars comprises three steps: (a) synthesis of a hydroxy-functional PVC [X-PVC(OH)n] by RAFT polymerization mediated by a hydroxy-functional xanthate [X-(OH)n], (b) conversion of the X-PVC(OH)n to the corresponding trithiocarbonate, X-PVC-(CDTPA)n, by the Steglich esterification with 4-cyano-4-[(dodecylsulfanylthiocarbonyl)sulfanyl]pentanoic acid (CDTPA), and (c) formation of star polymer additives by RAFT polymerization mediated by X-PVC-(CDTPA)n. The stars prepared include a plasticizer (B = Bu acrylate), a reactive dispersant for use in forming silica nanocomposites (B = 3-methacryloxypropyltrimethoxysilane), UV stabilizers (B = 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl methacrylate or 2-hydroxy-4-acryloxybenzophenone), and flame retardants (B = 4-vinylbenzyl phosphonate or diethyl(methacryloyloxymethyl)phosphonate). Although much optimization remains to be done, our preliminary study shows that the synthesized mikto-arm star additives can be effective in imparting the anticipated properties to PVC.

Macromolecules (Washington, DC, United States) published new progress about Dispersing agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Martin-Nieves, Virginia; Sanghvi, Yogesh S.; Fernandez, Susana; Ferrero, Miguel published the artcile< Sustainable Protocol for the Synthesis of 2′,3′-Dideoxynucleoside and 2′,3′-Didehydro-2′,3′-dideoxynucleoside Derivatives>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is 2′,3′-didehydro-2′,3′-dideoxynucleosides; 2′,3′-dideoxynucleosides; didanosine (ddI); stavudine (d4T); synthesis; zalcitabine (ddC).

An improved protocol for the transformation of ribonucleosides into 2′,3′-dideoxynucleoside and 2′,3′-didehydro-2′,3′-dideoxynucleoside derivatives, including the anti-HIV drugs stavudine (d4T), zalcitabine (ddC) and didanosine (ddI), was established. The process involves radical deoxygenation of xanthate using environmentally friendly and low-cost reagents. Bromoethane or 3-bromopropanenitrile was the alkylating agent of choice to prepare the ribonucleoside 2′,3′-bisxanthates. In the subsequent radical deoxygenation reaction, tris(trimethylsilyl)silane and 1,1′-azobis(cyclohexanecarbonitrile) were used to replace hazardous Bu3SnH and AIBN, resp. In addition, TBAF was substituted for camphorsulfonic acid in the deprotection step of the 5′-O-silyl ether group, and an enzyme (adenosine deaminase) was used to transform 2′,3′-dideoxyadenosine into 2′,3′-dideoxyinosine (ddI) in excellent yield.

Molecules published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lee, Bum Hoon; Jaung, Jae Yun; Jang, Se Chan; Yi, Sung Chul published the artcile< Synthesis and optical properties of push-pull type tetrapyrazinoporphyrazines>, Category: esters-buliding-blocks, the main research area is pyrazinoporphyrazine copper complex dye preparation fluorescence absorption spectra.

The optical properties of push-pull type tetrapyrazinoporphyrazine copper complexes based on 2,3-dicyanopyrazines were demonstrated. They have an alkoxyphenyl substituent as an electron donor group at the 5-position, and nitrophenyl or octylsulfonylphenyl substituents as an electron acceptor group at the 6-position of the 2,3-dicyanopyrazines. The absorption and fluorescence maxima of nitro-substituted compounds were observed at 427-444 and 453-494 nm, resp. In the case of the sulfonyl-substituted compounds, the hypsochromic shift of absorption and fluorescence maxima were 59-104 and 13-79 nm, resp.

Dyes and Pigments published new progress about Dyes. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Vila, Carlos; Dharmaraj, Nisshanth Raj; Faubel, Antonio; Blay, Gonzalo; Cardona, M. Luz; Munoz, M. Carmen; Pedro, Jose R. published the artcile< Regio-, Diastereo-, and Enantioselective Organocatalytic Addition of 4-Substituted Pyrazolones to Isatin-Derived Nitroalkenes>, Category: esters-buliding-blocks, the main research area is pyrazolone nitroalkene organocatalyst regioselective enantioselective diastereoselective nucleophilic vinylic substitution; chiral alkenylpyrazolone stereoselective preparation; hydroquinine diphenyl pyrimidinediyl diether catalyst.

Hydroquinine 2,5-diphenyl-4,6-pyrimidinediyl diether [(DHQ)2Pyr] catalyzed the regio-, diastereo-, and enantioselective addition of 4-substituted pyrazolones to isatin-derived nitroalkenes, providing a variety of chiral alkenylpyrazolone adducts, e.g., I, containing a tetrasubstituted stereocenter bearing an oxindole moiety with excellent yields, regioselectivity, and diastereoselectivity, as well as a moderate enantioselectivity (up to 98 % yield, > 20:1 E/Z ratio dr and 78 % ee). The reaction harnesses a nitroalkene as an alkenylating agent through a Nucleophilic Vinylic Substitution (SNV) reaction.

European Journal of Organic Chemistry published new progress about Alkenes, nitro Role: RCT (Reactant), RACT (Reactant or Reagent) (isatin-derived). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Das, Krishna Kumar; Jha, Sunil Kumar; Pattanaik, Gurudutta; Sharma, Yangya Prasad Nath; Behera, Santosh Kumar published the artcile< In silico analysis and network pharmacology of the impact of genes associated with multidrug-resistant tuberculosis (MDR-TB)>, Reference of 112-63-0, the main research area is gene network multidrug resistance tuberculosis.

Drug-resistant tuberculosis (DR-TB) continues to be a public health crisis worldwide during 2018. It estimates approx. 5,58,000 cases (range, 4,83,000-s6,39,000) developed TB resistant to rifampicin (RR-TB). The most effective first line drug, and of these, 82% had multidrug-resistant TB (MDR-TB). Three countries accounted for almost half of the world’s cases of MDR/RR-TB: India (24%), China (13%) and the Russian Federation (10%). Ample of studies were performed in India, based on the previously informed mutations, in addition to which several novel mutations were also observed in the genes such as rpoB (rifampicin), katG, the ribosomal binding site of inhA (isoniazid), gyrA and gyrB (ofloxacin), rpsL and rrs (streptomycin). The current investigation was carried out to explore the gene-gene interaction which are supposed to be the master regulators in MDR-TB. A total of 12 genes were mined from 618 publications in MalaCard which are responsible for MDR-TB. STRING network database reported the genes namely IL10, SLC11A1, TNF, DEFA3, DEFA1 at the core region of the network which are supposed to play a key role in TB. These genes may be also responsible for differentially expressed in MDR-TB disease. The Drug association anal. of Web Gestalt has reported 15 drugs interacted with 12 genes. In the current investigation we would like to suggest for further in vivo and in silico anal. of the reported genes for therapeutics of MDR-TB.

World Journal of Pharmaceutical Research published new progress about Animal gene Role: BSU (Biological Study, Unclassified), PRP (Properties), BIOL (Biological Study) (ACVR2A). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Choi, Woonghee; Kang, Yongku; Kim, In-Jung; Seong, Byeong-Gi; Yu, Woong-Ryeol; Kim, Dong Wook published the artcile< Stable Cycling of a 4 V Class Lithium Polymer Battery Enabled by In Situ Cross-Linked Ethylene Oxide/Propylene Oxide Copolymer Electrolytes with Controlled Molecular Structures>, Formula: C19H34O2, the main research area is stable cycling lithium polymer battery ethylene propylene oxide electrolyte; 4 V class lithium polymer batteries; electrochemical stability; ethylene oxide/propylene oxide copolymer; in situ cross-linking; solid polymer electrolytes.

Com. lithium-ion batteries are vulnerable to fire accidents, mainly due to volatile and flammable liquid electrolytes. Although solid polymer electrolytes (SPEs) are considered promising alternatives with antiflammability and processability for roll-to-roll mass production, several requirements have not yet been fulfilled for a viable lithium polymer battery. Such requirements include ionic conductivity, electrochem. stability, and interfacial resistance. In this work, the ionic conductivity of the SPEs is optimized by controlling the mol. weight and structural morphol. of the plasticizers as well as introducing propylene oxide (PO) groups. Electrochem. stability is also enhanced using ethylene oxide (EO)/PO copolymer electrolytes, making the SPEs compatible with high-Ni LiNixCoyMn1-x-yO2 cathodes. The in situ crosslinking method, in which a liquid precursor first wets the electrode and is then solidified by a subsequent thermal treatment, enables the SPEs to soak into the 60μm thick electrode with a high loading d. of more than 8 mg cm-2. Thus, interfacial resistance between the SPE and the electrode is minimized. By using the in situ cross-linked EO/PO copolymer electrolytes, we successfully demonstrate a 4 V class lithium polymer battery, which performs stable cycling with a marginal capacity fading even over 100 cycles.

ACS Applied Materials & Interfaces published new progress about Battery capacity. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics