Category: 10472-24-9

On September 8, 2022, Yee, Ka Yee; Leung, Man Pan; Tse, Man Ho; Choy, Pui Ying; Kwong, Fuk Yee published an article.Recommanded Product: 10472-24-9 The title of the article was Palladium-Catalyzed Direct C-H Olefination of Polyfluoroarenes with Alkenyl Tosylates. And the article contained the following:

The first general examples of palladium-catalyzed direct C-H olefination of polyfluoroarenes e.g., 1,2,3,4,5-pentafluorobenzene using alkenyl tosylates e.g., I as electrophilic coupling partners are presented. By employing the Pd/L1 catalyst system (L1 = N-methyl-2-(2′,4′-dimethoxyphenyl)-3-dicyclohexylphosphinoindole), the olefinated polyfluoroarenes e.g., II can be obtained in good-to-excellent yields. Good structural and functional compatibility are also exhibited. In particular, the steric demanding and heterocyclic alkenyl tosylates react smoothly under this catalyst system. This reaction can be practicably performed on a gram-scale without significantly loss of product yields. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Recommanded Product: 10472-24-9

The Article related to alkenyl polyfluoroarene preparation, polyfluoroarene alkenyl tosylate olefination palladium catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Recommanded Product: 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On August 20, 2021, He, Tianyu; Chen, Dengfeng; Qian, Shencheng; Zheng, Yu; Huang, Shenlin published an article.Application of 10472-24-9 The title of the article was Selective C-C Bond Cleavage of Cycloalkanones by NaNO2/HCl. And the article contained the following:

A novel selective fragmentation of cycloalkanones by NaNO2/HCl has been established. The C-C bond cleavage reaction proceeds smoothly under mild conditions, selectively affording versatile keto acids or oxime acids. The methodol. can streamline the synthesis of valuable chiral mols. and isocoumarins from readily available feedstocks. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Application of 10472-24-9

The Article related to keto oxime acid preparation, cycloalkanone selective bond cleavage, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.Application of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On February 15, 2020, Ye, Zhaolian; Zhuang, Yu; Chen, Yantong; Zhao, Zhuzi; Ma, Shuaishuai; Huang, Hongying; Chen, Yanfang; Ge, Xinlei published an article.Name: Methyl 2-cyclopentanonecarboxylate The title of the article was Aqueous-phase oxidation of three phenolic compounds by hydroxyl radical: Insight into secondary organic aerosol formation yields, mechanisms, products and optical properties. And the article contained the following:

This work performed a systematic investigation on the aqueous hydroxyl radical (OH) – induced photochem. oxidation of three modestly-soluble precursors from biomass combustion including 4-methylsyringol (DMP), eugenol (Eug), and 2,4,6-trimethylphenol (TRMP) under both simulated sunlight and UV light irradiations. An Aerodyne soot particle aerosol mass spectrometer (SP-AMS) was used to monitor the bulk chem. and elemental compositions of aqueous secondary organic aerosol (aqSOA) formed. AqSOA mass yields varied in ranges of 80-190% and 0-200% under sunlight and UV light conditions, resp. AqSOA oxygen-to-carbon (O/C) ratio and carbon oxidation state increased steadily under sunlight + OH condition, but increased then decreased under UV + OH condition. Organic acids including malic acid, glycolic acid, formic acid and oxalic acid were formed, and their total accounted for ∼12% of SOA mass. The UV-vis spectral change suggested formation of light-absorbing organics Reaction pathways were proposed by combining gas chromatog.-mass spectrometry (GC-MS) and SP-AMS results. Under sunlight + OH condition, oligomerization, functionalization, and fragmentation processes all involved in aqSOA evolution, with more contribution from functionalization via hydroxylation and oxygenation reactions. Reaction mechanism of UV + OH oxidation was initially dominated by functionalization then by fragmentation, indicating by the decrease of total organic carbon (TOC) contents, formation of small organic acids and low-mol.-weight products. Our work highlights that combination of SP-AMS with GC-MS is a powerful method for laboratory investigation of aqueous-phase reactions. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Name: Methyl 2-cyclopentanonecarboxylate

The Article related to phenolic compound oxidation hydroxyl radical secondary organic aerosol, Radiation Chemistry, Photochemistry, and Photographic and Other Reprographic Processes: Radiation Chemistry and Photochemistry and other aspects.Name: Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 31, 2021, Wang, Yakun; Wang, Shuaifei; Zhang, Conghui; Zhao, Ting; Hu, Yanqin; Zhang, Mingwei; Chen, Pengli; Fu, Yang published an article.Computed Properties of 10472-24-9 The title of the article was Highly Selective Difluoromethylations of β-Keto Amides with TMSCF2Br under Mild Conditions. And the article contained the following:

Without employing any transition metal and other additives, efficient methods for selective difluoromethylations of β-keto amides with TMSCF2Br reagent were developed under mild conditions. This protocol allowed a convenient access to various α-difluoromethyl β-keto amides with excellent yields (up to 93%) and high carbon/oxygen (C/O) regioselectivities (up to 99:1). The C/O selectivity of β-keto amides was easily reversed and controlled by simply changing the base. This protocol was easily scaled-up and the C-difluoromethylation product was reduced into CF2H-containing amino alc. derivatives Moreover, the first enantioselective electrophilic difluoromethylation of β-keto amides was achieved by phase-transfer catalysis. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Computed Properties of 10472-24-9

The Article related to keto amide bromodifluoromethyl trimethylsilane regioselective chemoselective difluoromethylation, difluoromethyl keto amide preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Computed Properties of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 6, 2020, Li, Ping; Sheng, Rong; Zhou, Zhiqiang; Hu, Guiwen; Zhang, Xiaoxiang published an article.Recommanded Product: Methyl 2-cyclopentanonecarboxylate The title of the article was Synthesis of N-Fused Seven-Membered Indoline-3-ones via a Palladium-Catalyzed One-Pot Insertion Reaction from 2-Alkynyl Arylazides and Cyclic β-Diketones. And the article contained the following:

A novel strategy to synthesize N-fused seven-membered multifunctional polycyclic indoline-3-one derivatives via insertion of cyclic C-acylimines into cyclic β-diketones was described. The reaction proceeded well under mild reaction conditions via a one-pot, three-steps method, which showed good tolerance of various functional groups. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Recommanded Product: Methyl 2-cyclopentanonecarboxylate

The Article related to indolineone nitrogen fused preparation palladium catalyst, alkynyl arylazide cyclic beta diketone insertion, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Recommanded Product: Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Nassar, Youssef; Piva, Olivier published an article in 2020, the title of the article was A short route to access oxaspiro[n,3,3]propellanes.Reference of Methyl 2-cyclopentanonecarboxylate And the article contains the following content:

Novel access to oxaspiro[n,3,3]propellanes was developed from bicyclic lactones directly prepared by a photochem. hydroxymethylation or alternatively by a three-step sequence. The presence of addnl. hydroxy- and propargylic groups, a second cyclization catalyzed by silver or bismuth salts, led to the propellane structure which was finally transformed into spiranic derivatives by a Simmons-Smith reaction or condensation with α-ketoesters. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Reference of Methyl 2-cyclopentanonecarboxylate

The Article related to oxo propynyl cyclohexane carboxylate silver bismuth catalyzed cyclization, oxaspirocyclopropane propellane preparation, oxaspiro lactone propellane preparation, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Reference of Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Miura, Tomoya; Moritani, Shunsuke; Shiratori, Yota; Murakami, Masahiro published an article in 2022, the title of the article was 1,2-Acyl migration with α-imino rhodium carbenoids leading to substituted 1-naphthols.Electric Literature of 10472-24-9 And the article contains the following content:

A unique method for the synthesis of substituted 1-naphthols I (R = Ts, Ms, R1 = 6-F, 6-Cl, 7-Me, etc., R2 = Me, CO2Me) by rhodium(II)-catalyzed ring-expansion reaction of 2-triazolyl-1-indanone derivatives II (R3 = 5-F, 5-Cl, 6-Me, etc.) is reported. 1,2-Acyl migration occurs with an intermediate α-imino rhodium carbenoid generated from the triazolyl moiety. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Electric Literature of 10472-24-9

The Article related to naphthol preparation, triazolyl indanone ring expansion acyl migration rhodium catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Electric Literature of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 31, 2021, Veverkova, Eva; Molnosiova, Pavlina; Sebesta, Radovan published an article.Recommanded Product: 10472-24-9 The title of the article was Asymmetric Sequential Michael Addition and Cyclization Reactions of 2-(2-Nitrovinyl)phenols Catalyzed by Bifunctional Amino-Squaramides. And the article contained the following:

In this work, authors describe the Michael addition-cyclization reaction of 2-(2-nitrovinyl)phenol with two different reactive Michael donors, which lead to chiral benzopyran derivatives Specifically, bifunctional amino-squaramides with one or two chiral units in the side chains were evaluated as catalysts in these transformations. Furthermore, the utility of selected green solvents as reaction media for these processes was also tested. The best result was achieved with methyl-cyclopentanone-2-carboxylate as the Michael donor in Et (-)- L-lactate with quinine-based amino-squaramide as catalyst (yield 72%, dr >99:1, ee 99%). The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Recommanded Product: 10472-24-9

The Article related to chiral benzopyran preparation, nitrovinylphenol michael addition cyclization reaction, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Recommanded Product: 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 1, 2020, Wang, Shuai; Ma, Xu-Bin; Yuan, Xiao-Han; Yu, Bin; Xu, Yi-Chao; Liu, Hong-Min published an article.Product Details of 10472-24-9 The title of the article was Discovery of new [1,2,4] Triazolo[1,5-a]Pyrimidine derivatives that Kill gastric cancer cells via the mitochondria pathway. And the article contained the following:

A novel series of [1,2,4]triazolo[1,5-a]pyrimidine-based compoundsI [R1 = benzyl, 4-fluorobenzyl, 4-chlorobenzyl, etc.; R2 = Me, Et, Ph; R3 = H, Me] and II [R4 = Ph, (4-(3-(6-bromo-2-pyridyl)prop-2-enoyl)phenyl), (4-(3-(5-bromo-2-pyridyl)prop-2-enoyl)phenyl), etc.] were synthesized and tested their anti-proliferation efficacy against gastric cancer cell line MGC-803. Among them, compounds II [R4 = (4-(3-(6-bromo-2-pyridyl)prop-2-enoyl)phenyl), (4-(3-(5-bromo-2-pyridyl)prop-2-enoyl)phenyl)] inhibited gastric cancer cells at micromolar level. Compound II [R4 = (4-(3-(6-bromo-2-pyridyl)prop-2-enoyl)phenyl)] caused G2/M arrest and induced mitochondria-dependent apoptosis in MGC-803 and SGC-7901. However, inhibiting apoptosis pathway cannot prevent the inhibitory activity of compound II [R4 = (4-(3-(6-bromo-2-pyridyl)prop-2-enoyl)phenyl)] against gastric cancer cell. To our surprising, ROS level was increased by compound II [R4 = (4-(3-(6-bromo-2-pyridyl)prop-2-enoyl)phenyl)] and elevation of ROS could be rescued by NAC. In accordance with that, NAC absolutely prevented the anti-proliferation efficacy of compound 4o. We further found that autophagy inhibitor CQ rather than 3-MA partially reversed inhibitory activity of compound II [R4 = (4-(3-(6-bromo-2-pyridyl)prop-2-enoyl)phenyl)] in MGC-803 cells. Taken together, compound II [R4 = (4-(3-(6-bromo-2-pyridyl)prop-2-enoyl)phenyl)] exhibited its anti-proliferative activity via increasing ROS level and inducing autophagy, thus leading to apoptosis of gastric cancer cells. Therefore, compound II [R4 = (4-(3-(6-bromo-2-pyridyl)prop-2-enoyl)phenyl)] may support further development of lead compounds for gastric cancer therapy via mitochondria pathway. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Product Details of 10472-24-9

The Article related to triazolopyrimidinylamino diarylpropenone preparation antitumor activity sar, 1,2,4]triazolo[1,5-a]pyrimidines, apoptosis, autophagy, gastric cancer, mitochondrial pathway and other aspects.Product Details of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On September 1, 2021, Matsumoto, Akira; Shiozaki, Yoko; Sakurai, Shunya; Maruoka, Keiji published an article.Computed Properties of 10472-24-9 The title of the article was Synthesis of Functionalized Aliphatic Acid Esters via the Generation of Alkyl Radicals from Silylperoxyacetals. And the article contained the following:

We describe a catalytic method for the synthesis of a variety of functionalized aliphatic acid esters using silylperoxyacetals, which are versatile alkyl radical precursors with a terminal ester moiety. In the presence of an appropriate transition-metal catalyst, the in situ generation of alkyl radicals and the subsequent bond-forming process proceeds smoothly to afford synthetically valuable aliphatic acid derivatives [e.g., silylperoxyacetal I + PhCONH2 → II (83%) in presence of CuI/1,10-phenanthroline]. The present method can be applied to the efficient synthesis of a pharmaceutically important 1,1-diarylalkane motif. In addition, a novel strategy for the synthesis of structurally diverse hydroxy acid derivatives via a C-O bond formation process that utilizes TEMPO has been developed. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Computed Properties of 10472-24-9

The Article related to aliphatic acid ester synthesis silylperoxy acetal alkyl radical generation, c−c bond cleavage, alkyl radicals, hydroxy acids, iron-catalysis, silylperoxyacetals, β-scission and other aspects.Computed Properties of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics