Category: 103-26-4

Authors Terao, Y; Sugihara, S; Satoh, K; Kamigaito, M in PERGAMON-ELSEVIER SCIENCE LTD published article about ANETHOLE; MONOMERS; POLYMERS in [Terao, Yuya; Sugihara, Shizuka; Satoh, Kotaro; Kamigaito, Masami] Nagoya Univ, Grad Sch Engn, Dept Mol & Macromol Chem, Chikusa Ku, Furo Cho, Nagoya, Aichi 4648603, Japan; [Satoh, Kotaro] Tokyo Inst Technol, Sch Mat & Chem Technol, Dept Chem Sci & Engn, Meguro Ku, 2-12-1 Ookayama, Tokyo 1528550, Japan in 2019.0, Cited 33.0. Application In Synthesis of Methyl 3-phenyl-2-propenoate. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4

Methyl cinnamate (M-1) and maleic anhydride (M-2), which are both non-homopolymerizable 1,2-disubtituted vinyl monomers, were radically copolymerized in toluene to result in 1:1 alternating copolymers. The 1:1 alternating sequence was confirmed by not only the monomer reactivity ratios obtained by using the terminal model fitted by the Kelen-Tiidos method (r(1) = 0.0035, r(2) = 0.069) but also MALDI-TOF-MS analysis of the copolymers with controlled molecular weights and relatively narrow molecular weight distributions (M-w/M-n = 1.20), which were prepared by RAFT copolymerization using 2-cyano-2-propyl ethyl trithiocarbonate (CPETC) as the RAFT agent. The maleic anhydride unit was transformed into two methyl ester groups by hydrolysis followed by methylation. Since the propagation of methyl cinnamate occurred regioselectively via a styrenic radical, the methyl esterified copolymers possessed ABAA sequence-controlled substituted polymethylene structures (A: methyl ester, B: phenyl). The sequence-controlled substituted polymethylene showed good thermal properties (T-d5 = 323 degrees C, T-g >= 192 degrees C) due to the rigid main-chain structures, which possessed a phenyl group on every fourth main-chain carbon in the repeating units in addition to three methyl ester groups on the other main-chain carbons. Block copolymers consisting of the rigid substituted polymethylene and soft poly(methyl acrylate) were also synthesized by RAFT polymerization.

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Terao, Y; Sugihara, S; Satoh, K; Kamigaito, M or concate me.. Application In Synthesis of Methyl 3-phenyl-2-propenoate

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

SDS of cas: 103-26-4. Authors Fischer, O; Heinrich, MR in WILEY-V C H VERLAG GMBH published article about in [Fischer, Oliver; Heinrich, Markus R.] Friedrich Alexander Univ Erlangen Nurnberg, Dept Chem & Pharm, Pharmaceut Chem, Nikolaus Fiebiger Str 10, D-91058 Erlangen, Germany in 2021.0, Cited 87.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4

As a novel Sanger-type reagent, 2-fluoro-5-nitrophenyldiazonium tetrafluoroborate enabled the versatile functionalization of primary and secondary aliphatic alcohols. Based on a mild nucleophilic aromatic substitution of the fluorine atom under unprecedented, base-free conditions, the diazonium unit on the aromatic core of the resulting aryl-alkyl ether could be employed for such diverse transformations as radical C-H activation and cyclization, as well as palladium catalyzed cross-coupling reactions.

SDS of cas: 103-26-4. About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Fischer, O; Heinrich, MR or concate me.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

HPLC of Formula: C10H10O2. I found the field of Chemistry very interesting. Saw the article Scope and Mechanism of the Ruthenium-Catalyzed Dehydrative C-H Coupling of Phenols with alpha,beta-Unsaturated Carbonyl Compounds: Expedient Synthesis of Chromene and Benzoxacyclic Derivatives published in 2019.0, Reprint Addresses Yi, CS (corresponding author), Marquette Univ, Dept Chem, Milwaukee, WI 53233 USA.. The CAS is 103-26-4. Through research, I have a further understanding and discovery of Methyl 3-phenyl-2-propenoate.

Chromene and benzoxacyclic derivatives were efficiently synthesized from the ruthenium-catalyzed dehydrative C-H coupling reaction of phenols with alpha,beta-unsaturated carbonyl compounds. The cationic ruthenium-hydride complex was found to be an effective catalyst for the coupling and annulation of phenols with enals to form chromene products. The coupling of phenols with linear enones afforded 2,4-disubstituted chromene derivatives, whereas the analogous coupling with cyclic enones yielded 9-hydroxybenzoxazole products. The reaction of 3,5-dimethoxyphenol with PhCH=CHCDO resulted in the chromene product with a significant H/D exchange to both benzylic and vinyl positions. The most significant carbon isotope effect from the coupling of 3,5-dimethoxyphenol with 4-methoxycinnamaldehyde was observed on the a-olefinic carbon of the chromene product (C(2) = 1.067). A Hammett plot from the coupling of 3,5-dimethoxyphenol with para-substituted p-X-C6H4CH=CHCHO displayed a linear correlation, with a strong promotional effect by an electron -withdrawing group (rho = +1.5; X = OCH3, CH3, H, F, Cl). Several biologically active chromenone derivatives were synthesized by using the catalytic coupling method. The catalytic method provides an expedient synthetic protocol for the coupling of phenols with alpha,beta-unsaturated carbonyl compounds without employing reactive reagents or forming any wasteful byproducts.

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Mokar, BD; Yi, CS or concate me.. HPLC of Formula: C10H10O2

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Category: esters-buliding-blocks. I found the field of Chemistry very interesting. Saw the article Semireduction of alkynoic acids via a transition metal-free alpha borylation-protodeborylation sequence published in 2019.0, Reprint Addresses Santos, WL (corresponding author), Virginia Tech, Dept Chem, Blacksburg, VA 24061 USA.. The CAS is 103-26-4. Through research, I have a further understanding and discovery of Methyl 3-phenyl-2-propenoate.

A method for the semi-reduction of alkynoic acids through an alpha-borylation and subsequent protodeborylation mechanism has been developed. The transition metal-free protocol is achieved through the activation of bis(pinacolato)diboron by an in situ generated carboxylate moiety yielding aryl acrylic acids. Our studies demonstrate an unprecedented dual role for the carboxylate anion that involves the activation of the diboron reagent and a directing effect in the alpha-borylation. (C) 2019 Elsevier Ltd. All rights reserved.

Category: esters-buliding-blocks. About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Verma, A; Grams, RJ; Rastatter, BP; Santos, WL or concate me.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Planar Chiral [2.2]Paracyclophane-Based Bisoxazoline Ligands and Their Applications in Cu-Mediated N-H Insertion Reaction WOS:000501529700111 published article about ASYMMETRIC CONJUGATE ADDITION; ENANTIOSELECTIVE INSERTION; BONDS; CATALYSTS; DESIGN; IMINES in [Knoll, Daniel M.; Hu, Yuling; Hassan, Zahid; Braese, Stefan] Karlsruhe Inst Technol, IOC, Fritz Haber Weg 6, D-76131 Karlsruhe, Germany; [Nieger, Martin] Univ Helsinki, Dept Chem, POB 55 AI Virtasen Aukio 1, FIN-00014 Helsinki, Finland; [Braese, Stefan] Karlsruhe Inst Technol, ITG, Hermann von Helmholtz Pl 1, D-76344 Eggenstein Leopoldshafen, Germany in 2019.0, Cited 26.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. Product Details of 103-26-4

New catalysts for important C-N bond formation are highly sought after. In this work, we demonstrate the synthesis and viability of a new class of planar chiral [2.2]paracyclophane-based bisoxazoline (BOX) ligands for the copper-catalyzed N-H insertion of alpha -diazocarbonyls into anilines. The reaction features a wide substrate scope and moderate to excellent yields, and delivers the valuable products at ambient conditions.

Product Details of 103-26-4. About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Knoll, DM; Hu, YL; Hassan, Z; Nieger, M; Brase, S or concate me.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Quality Control of Methyl 3-phenyl-2-propenoate. Authors Song, NE; Kim, MK; Lee, KG; Jang, HW in ELSEVIER published article about in [Song, Nho-Eul; Jang, Hae Won] Korea Food Res Inst, 245 Nongsaengmyeong Ro, Wanju Gun 55365, Jeollabuk Do, South Korea; [Kim, Mina K.] Jeonbuk Natl Univ, Dept Food Sci & Human Nutr, 567 Baekjedaero, Jeonju Si 54896, Jeonbuk, South Korea; [Kim, Mina K.] Jeonbuk Natl Univ, Fermented Food Res Ctr, 567 Baekjedaero, Jeonju Si 54896, Jeonbuk, South Korea; [Lee, Kwang-Geun] Dongguk Univ Seoul, Dept Food Sci & Biotechnol, 32 Dongguk Ro, Goyang Si 10326, Gyeonggi Do, South Korea; [Jang, Hae Won] Sungshin Womens Univ, Dept Food Sci & Biotechnol, 55 Dobong Ro 76 Ga Gil, Seoul 01133, South Korea in 2021.0, Cited 45.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4

This study aimed to comparatively analyze the volatile flavor of rooibos tea (Aspalathus linearis) obtained by two commonly used flavor extraction methods, simultaneous distillation-extraction (SDE) and steam distillation under reduced pressure (DRP). The tea obtained by the two extraction methods, were analyzed by gas chromatography-mass spectrometry to identify volatile aroma-related compounds. Descriptive sensory analysis of the extracted rooibos tea flavor was carried out by a trained panel (n = 7). Fifty volatile compounds were identified, including 26 and 25 aroma-active compounds by SDE (45.9 mu g/g) and DRP (37.5 mu g/g), respectively. SDE recovered larger quantities of alcohols, acids, and esters, whereas DRP was useful for analyzing thermally unstable volatile compounds, including various alcohols, aldehydes, and hydrocarbons. Descriptive sensory analysis revealed that ketones and phenolic compounds may be responsible for the sensory attributes woody and grassy green, whereas the aldehydes and acidic compounds may contribute to floral and fruity.

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Song, NE; Kim, MK; Lee, KG; Jang, HW or concate me.. Quality Control of Methyl 3-phenyl-2-propenoate

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2021.0 ECLINICALMEDICINE published article about ACUTE-CARE UTILIZATION; ALCOHOL-CONSUMPTION; RISK; IMPACT; INDIVIDUALS; QUESTIONNAIRE; DEPRESSION; MORTALITY; ADMISSION; INFECTION in [Rein, Sophia M.; Smith, Colette J.; Chaloner, Clinton; Rodger, Alison J.; McDonnell, Jeffrey; Burns, Fiona; Sherr, Lorraine; Speakman, Andrew; Phillips, Andrew N.; Lampe, Fiona C.] UCL, Inst Global Hlth, London, England; [Stafford, Adam; Johnson, Margaret A.; Burns, Fiona; Madge, Sara] Royal Free London NHS Fdn Trust, London, England; [Collins, Simon] HIV I Base, London, England; [Miners, Alec] London Sch Hyg & Trop Med LSHTM, London, England in 2021.0, Cited 38.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. Safety of Methyl 3-phenyl-2-propenoate

Background: Predictors of hospitalisation in people with HIV (PLHIV) in the contemporary treatment era are not well understood. Methods: This ASTRA sub-study used clinic data linkage and record review to determine occurrence of hospitalisations among 798 PLHIV from baseline questionnaire (February to December 2011) until 1 June 2018. Associations of baseline social circumstance, socioeconomic, lifestyle, mental health, demographic and clinical factors with repeated all-cause hospitalisation from longitudinal data were investigated using Prentice-Williams-Peterson models. Associations were also assessed in 461 individuals on antiretroviral therapy (ART) with viral load <= 50 copies/ml and CD4 count >= 500 cells/ mu l. Findings: Rate of hospitalisation was 5.8/100 person-years (95% CI: 5.1-6.5). Adjusted for age, demographic group and time with diagnosed HIV, the following social circumstance, socioeconomic, lifestyle and mental health factors predicted hospitalisation: no stable partner (adjusted hazard ratio (aHR)=1.59; 95% CI=1.16-2.20 vs living with partner); having children (aHR=1.50; 1.08-2.10); non-employment (aHR=1.56; 1.07-2.27 for unemployment; aHR=2.39; 1.70-3.37 for sick/disabled vs employed); rented housing (aHR=1.72; 1.26-2.37 vs homeowner); not enough money for basic needs (aHR=1.82; 1.19-2.78 vs enough); current smoking (aHR=1.39; 1.02-1.91 vs never); recent injection-drug use (aHR=2.11; 1.30-3.43); anxiety symptoms (aHRs=1.39; 1.01-1.91, 2.06; 1.43-2.95 for mild and moderate vs none/minimal); depressive symptoms (aHRs=1.67; 1.17-2.38, 1.91; 1.30-2.78 for moderate and severe vs none/minimal); treated/untreated depression (aHRs=1.65; 1.03-2.64 for treated depression only, 1.87; 1.39-2.52 for depressive symptoms only; 1.53; 1.05-2.24; for treated depression and depressive symptoms, versus neither). Associations were broadly similar in those with controlled HIV and high CD4. Interpretation: Social circumstance, socioeconomic disadvantage, adverse lifestyle factors and poorer mental health are strong predictors of hospitalisation in PLHIV, highlighting the need for targeted interventions and care. (c) 2020 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Rein, SM; Smith, CJ; Chaloner, C; Stafford, A; Rodger, AJ; Johnson, MA; McDonnell, J; Burns, F; Madge, S; Miners, A; Sherr, L; Collins, S; Speakman, A; Phillips, AN; Lampe, FC or concate me.. Safety of Methyl 3-phenyl-2-propenoate

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Formula: C10H10O2. Authors Krizkovska, B; Kumar, R; Rehorova, K; Sykora, D; Dobiasova, S; Kucerova, D; Tan, MC; Linis, V; Oyong, G; Ruml, T; Lipov, J; Viktorova, J in MDPI published article about in [Krizkovska, Bara; Kumar, Rohitesh; Rehorova, Katerina; Dobiasova, Simona; Kucerova, Denisa; Ruml, Tomas; Lipov, Jan; Viktorova, Jitka] Univ Chem & Technol Prague, Dept Biochem & Microbiol, Tech 5, Prague 16628, Czech Republic; [Sykora, David] Univ Chem & Technol Prague, Dept Analyt Chem, Tech 5, Prague 16628, Czech Republic; [Tan, Maria Carmen] De La Salle Univ, Dept Chem, 2401 Taft Ave, Manila 1004, Philippines; [Linis, Virgilio] De La Salle Univ, Dept Biol, 2401 Taft Ave, Manila 1004, Philippines; [Oyong, Glenn] De La Salle Univ, Mol Sci Unit Lab, Ctr Nat Sci & Environm Res, 2401 Taft Ave, Manila 1004, Philippines in 2021.0, Cited 66.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4

Selaginella P. Beauv. is a group of vascular plants in the family Selaginellaceae Willk., found worldwide and numbering more than 700 species, with some used as foods and medicines. The aim of this paper was to compare methanolic (MeOH) and dichloromethane (DCM) extracts of eight Selaginella species on the basis of their composition and biological activities. Six of these Selaginella species are underinvestigated. Using ultra-high performance liquid chromatography-high-resolution mass spectrometry (UHPLC-HRMS) analysis, we identified a total of 193 compounds among the tested Selaginella species, with flavonoids predominating. MeOH extracts recovered more constituents that were detected, including selaginellins, the occurrence of which is only typical for this plant genus. Of all the tested species, Selaginella apoda contained the highest number of identified selaginellins. The majority of the compounds were identified in S. apoda, the fewest compounds in Selaginella cupressina. All the tested species demonstrated antioxidant activity using oxygen radical absorption capacity (ORAC) assay, which showed that MeOH extracts had higher antioxidant capacity, with the half maximal effective concentration (EC50) ranging from 12 +/- 1 (Selaginella myosuroides) to 124 +/- 2 (Selaginella cupressina) mg/L. The antioxidant capacity was presumed to be correlated with the content of flavonoids, (neo)lignans, and selaginellins. Inhibition of acetylcholinesterase (AChE) was mostly discerned in DCM extracts and was only exhibited in S. myosuroides, S. cupressina, Selaginella biformis, and S. apoda extracts with the half maximal inhibitory concentration (IC50) in the range of 19 +/- 3 to 62 +/- 1 mg/L. Substantial cytotoxicity against cancer cell lines was demonstrated by the MeOH extract of S. apoda, where the ratio of the IC50 HEK (human embryonic kidney) to IC50 HepG2 (hepatocellular carcinoma) was 7.9 +/- 0.2. MeOH extracts inhibited the production of nitrate oxide and cytokines in a dose-dependent manner. Notably, S. biformis halved the production of NO, tumor necrosis factor (TNF)-alpha, and interleukin (IL)-6 at the following concentrations: 105 +/- 9, 11 +/- 1, and 10 +/- 1 mg/L, respectively. Our data confirmed that extracts from Selaginella species exhibited cytotoxicity against cancer cell lines and AChE inhibition. The activity observed in S. apoda was the most promising and is worth further exploration.

Formula: C10H10O2. About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Krizkovska, B; Kumar, R; Rehorova, K; Sykora, D; Dobiasova, S; Kucerova, D; Tan, MC; Linis, V; Oyong, G; Ruml, T; Lipov, J; Viktorova, J or concate me.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2019.0 INT J MOL SCI published article about FATTY LIVER-DISEASE; HEPATIC CYTOCHROME-P450 1A1; MESSENGER-RNA EXPRESSION; POTENTIAL ANKYRIN 1; ANDROGEN RECEPTOR; DANHONG INJECTION; OXIDATIVE STRESS; GENE-EXPRESSION; CYP 1A1; PLATELET-AGGREGATION in [Chen, Zhao; Cao, Yanfeng; Zhang, Yanling; Qiao, Yanjiang] Beijing Univ Chinese Med, Sch Chinese Mat Med, Beijing 102488, Peoples R China; [Chen, Zhao; Cao, Yanfeng; Zhang, Yanling; Qiao, Yanjiang] State Adm Tradit Chinese Med, Res Ctr TCM Informat Engn, Beijing 102488, Peoples R China in 2019.0, Cited 179.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. Quality Control of Methyl 3-phenyl-2-propenoate

Pungent traditional Chinese medicines (TCMs) play a vital role in the clinical treatment of hepatobiliary disease, gastrointestinal diseases, cardiovascular diseases, diabetes, skin diseases and so on. Pungent TCMs have a vastness of pungent flavored (with pungent taste or smell) compounds. To elucidate the molecular mechanism of pungent flavored compounds in treating cardiovascular diseases (CVDs) and liver diseases, five pungent TCMs with the action of blood-activating and stasis-resolving (BASR) were selected. Here, an integrated systems pharmacology approach is presented for illustrating the molecular correlations between pungent flavored compounds and their holistic efficacy at the special organ level. First, we identified target proteins that are associated with pungent flavored compounds and found that these targets were functionally related to CVDs and liver diseases. Then, based on the phenotype that directly links human genes to the body parts they affect, we clustered target modules associated with pungent flavored compounds into liver and heart organs. We applied systems-based analysis to introduce a pungent flavored compound-target-pathway-organ network that clarifies mechanisms of pungent substances treating cardiovascular diseases and liver diseases by acting on the heart/liver organ. The systems pharmacology also suggests a novel systematic strategy for rational drug development from pungent TCMs in treating cardiovascular disease and associated liver diseases.

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Chen, Z; Cao, YF; Zhang, YL; Qiao, YJ or concate me.. Quality Control of Methyl 3-phenyl-2-propenoate

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Safety of Methyl 3-phenyl-2-propenoate. Recently I am researching about NF-KAPPA-B; ANTI-INFLAMMATION; CYTOTOXIC CONSTITUENTS; ANTIOXIDANT; EXPRESSION; SUBAMOLIDE; APOPTOSIS; PATHWAYS; LEAVES; CELLS, Saw an article supported by the Hubei Provincial Outstanding Young and Middle-Aged Science and Technology Innovation Team Project [T201813]; Young Scientist Innovation Team Project of Hubei Colleges [T201510]; Hubei Province Health and Family Planning Scientific Research Project [WJ2017Z023]. Published in HINDAWI LTD in LONDON ,Authors: Hao, XC; Sun, WG; Ke, CB; Wang, FQ; Xue, YB; Luo, ZW; Wang, XB; Zhang, JW; Zhang, YH. The CAS is 103-26-4. Through research, I have a further understanding and discovery of Methyl 3-phenyl-2-propenoate

The study determined the chemical constituents and anti-inflammatory effects of leaf oil from Cinnamomum subavenium (CS-LO) that has been used in folk medicine to treat various symptoms including inflammation. The anti-inflammatory effects of the oil were evaluated by LPS-stimulated RAW264.7 cells and the Carr-induced hind mouse paw edema model, respectively. In vitro, nitric oxide (NO), prostaglandin E2 (PGE(2)), TNF-, IL-6, and IL-1 were significantly decreased by CS-LO, and the expression of nuclear factor-B (NF-B) protein was blocked as well. In in vivo, the malondialdehyde (MDA) and paw edema levels were decreased by CS-LO, and the same result came up on the NO and tumor necrosis factor (TNF-a) of serum at the 5th h after Carr injection. In addition, iNOS and COX-2 immunoreactive cells of the paw tissue were decreased significantly by CS-LO (200 mg/kg) in histological examination. The present findings indicated that CS-LO have anti-inflammatory properties, and the effects might be caused through inhibiting iNOS, COX-2, TNF-, IL-1, and IL-6 expression via affecting NF-B pathway, which will provide a power scientific basis for CS-LO to be used as the treatment of inflammatory diseases.

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Hao, XC; Sun, WG; Ke, CB; Wang, FQ; Xue, YB; Luo, ZW; Wang, XB; Zhang, JW; Zhang, YH or concate me.. Safety of Methyl 3-phenyl-2-propenoate

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics