Category: 103-25-3

COA of Formula: C10H12O2. Recently I am researching about POSITRON-EMISSION-TOMOGRAPHY; CARBOXYLIC-ACIDS; MERGING PHOTOREDOX; H BONDS; FLUORINE; NICKEL; DEOXYFLUORINATION; CARBOFLUORINATION; CATALYSIS; DERIVATIVES, Saw an article supported by the National University of Singapore President’s Assistant Professorship start-up grant [R-143-000-A50-133]; NSFNational Science Foundation (NSF) [CAREER 1751568]; University of Maryland College Park; XSEDE [CHE160082, CHE160053]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Wang, HY; Liu, CF; Song, ZH; Yuan, MB; Ho, YA; Gutierrez, O; Koh, MJ. The CAS is 103-25-3. Through research, I have a further understanding and discovery of Methyl 3-phenylpropionate

Fluorine-containing organic molecules, particularly those that bear (sp(3))C-F bonds, are rapidly gaining prominence in modern chemical synthesis. Although extensive studies have been devoted to the preparation of secondary and tertiary fluorides, crucial shortcomings remain: for example, lengthy substrate synthesis, contrived installation of difficult-to-remove directing/activating units, excessive waste generation and/or limited functional group compatibility. Here, we show that readily accessible alpha-onofluoro carboxylic acids, which are conventionally difficult substrates for cross-coupling, undergo direct decarboxylative crosscoupling with sp(2-) and sp(3-)hybridized organohalides to afford a wide assortment of fluorinated products. Reactions are typically promoted by a combination of 1 mol % of an Ir-based photocatalyst and 2-15 mol % of a bipyridine-Ni complex, delivering products in up to 86% yield under blue LED light irradiation. Concise synthesis of key therapeutic candidates underscores utility, complementarity, and distinct advantages compared with existing methods. DFT calculations are used to rationalize the distinct reactivity of alpha-fluoro carboxylic acid substrates (vs nonfluorinated parent acids) under decarboxylation conditions.

COA of Formula: C10H12O2. About Methyl 3-phenylpropionate, If you have any questions, you can contact Wang, HY; Liu, CF; Song, ZH; Yuan, MB; Ho, YA; Gutierrez, O; Koh, MJ or concate me.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Name: Methyl 3-phenylpropionate. I found the field of Chemistry very interesting. Saw the article Aldehyde effect and ligand discovery in Ru-catalyzed dehydrogenative cross-coupling of alcohols to esters published in 2019.0, Reprint Addresses Zhao, DM (corresponding author), Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China.; Li, YH (corresponding author), Chinese Acad Sci, State Key Lab Oxo Synth & Select Oxidat, Lanzhou Inst Chem Phys, Suzhou Res Inst LICP, Lanzhou 730000, Peoples R China.. The CAS is 103-25-3. Through research, I have a further understanding and discovery of Methyl 3-phenylpropionate.

The presence of different aldehydes is found to have a significant influence on the catalytic performance when using PN(H)P type ligands for dehydrogenation of alcohols. Accordingly, hybrid multi-dentate ligands were discovered based on an oxygen-transfer alkylation of PNP ligands by aldehydes. The relevant Ru-PNN(PO) system provided the desired unsymmetrical esters in good yields via acceptorless dehydrogenation of alcohols. Hydrogen bonding interactions between the phosphine oxide moieties and alcohol substrates likely assisted the observed high chemoselectivity.

Name: Methyl 3-phenylpropionate. Welcome to talk about 103-25-3, If you have any questions, you can contact Jiang, XL; Zhang, JH; Zhao, DM; Li, YH or send Email.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Nickel-Catalyzed Selective Reduction of Carboxylic Acids to Aldehydes WOS:000489200100026 published article about DIRECT HYDROGENATION; DIRECT CONVERSION; ALKYL-HALIDES; HYDROSILYLATION; HYDRIDE; KETONES; ANHYDRIDES; BASE; MILD; DISCOVERY in [Iosub, Andrei, V; Moravcik, Stefan; Bergman, Joakim] AstraZeneca, BioPharmaceut R&D, Med Chem Res & Early Dev Cardiovasc, Renal & Metab, Gothenburg, Sweden; [Wallentin, Carl-Johan] Gothenburg Univ, Dept Chem & Mol Biol, Gothenburg, Sweden in 2019.0, Cited 66.0. Name: Methyl 3-phenylpropionate. The Name is Methyl 3-phenylpropionate. Through research, I have a further understanding and discovery of 103-25-3

The direct reduction of carboxylic acids to aldehydes is a fundamental transformation in organic synthesis. The combination of an air-stable Ni precatalyst, dimethyl dicarbonate as an activator, and silane reductant effects this reduction for a wide variety of substrates, including pharmaceutically relevant structures, in good yields and with no overreduction to alcohols. Moreover, this methodology is scalable, allows access to deuterated aldehydes, and is also compatible with one-pot utilization of the aldehyde products.

Welcome to talk about 103-25-3, If you have any questions, you can contact Iosub, AV; Moravcik, S; Wallentin, CJ; Bergman, J or send Email.. Name: Methyl 3-phenylpropionate

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2020.0 EUR J ORG CHEM published article about HIGHLY SELECTIVE FORMATION; REGIOSELECTIVE CATALYSTS; METHANOL CARBONYLATION; UNSATURATED ESTERS; ALLYLIC ALCOHOLS; COMPLEXES; ALKYNES; HYDROFORMYLATION; ALKENES; METHOXYCARBONYLATION in [Schneider, Carolin; Jackstell, Ralf; Beller, Matthias] Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany; [Maes, Bert U. W.] Univ Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, Belgium in 2020.0, Cited 52.0. The Name is Methyl 3-phenylpropionate. Through research, I have a further understanding and discovery of 103-25-3. Formula: C10H12O2

Herein, we report the palladium-catalyzed synthesis of 3-arylpropionate esters starting from secondary benzylic ethers. With this investigation it could be shown that ethers are suitable starting materials in addition to the established carbonylation reactions of olefins, alcohols, or aryl halides.

Welcome to talk about 103-25-3, If you have any questions, you can contact Schneider, C; Jackstell, R; Maes, BUW; Beller, M or send Email.. Formula: C10H12O2

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

COA of Formula: C10H12O2. In 2020.0 EUR J ORG CHEM published article about HIGHLY SELECTIVE FORMATION; REGIOSELECTIVE CATALYSTS; METHANOL CARBONYLATION; UNSATURATED ESTERS; ALLYLIC ALCOHOLS; COMPLEXES; ALKYNES; HYDROFORMYLATION; ALKENES; METHOXYCARBONYLATION in [Schneider, Carolin; Jackstell, Ralf; Beller, Matthias] Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany; [Maes, Bert U. W.] Univ Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, Belgium in 2020.0, Cited 52.0. The Name is Methyl 3-phenylpropionate. Through research, I have a further understanding and discovery of 103-25-3.

Herein, we report the palladium-catalyzed synthesis of 3-arylpropionate esters starting from secondary benzylic ethers. With this investigation it could be shown that ethers are suitable starting materials in addition to the established carbonylation reactions of olefins, alcohols, or aryl halides.

COA of Formula: C10H12O2. Welcome to talk about 103-25-3, If you have any questions, you can contact Schneider, C; Jackstell, R; Maes, BUW; Beller, M or send Email.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Vicinal Diboration of Alkyl Bromides via Tandem Catalysis published in 2019.0. Recommanded Product: Methyl 3-phenylpropionate, Reprint Addresses Lu, X; Fuo, Y (corresponding author), Univ Sci & Technol China, iChEM, Anhui Prov Key Lab Biomass Clean Energy, Hefei Natl Lab Phys Sci Microscale,CAS Key Lab Ur, Hefei 230026, Anhui, Peoples R China.. The CAS is 103-25-3. Through research, I have a further understanding and discovery of Methyl 3-phenylpropionate

Vicinal diboration of alkyl bromides via tandem catalysis is reported. The reported reaction exhibits a broad substrate scope, good functional group compatibility, and regioselectivity. Moreover, it shows good practicality due to the easy accessibility of alkyl bromides in combination with diverse transformations of diboronates. Mechanism study indicates that terminal alkenes are generated selectively through nickel-catalyzed dehydrohalogenation of alkyl bromides followed by base/MeOH promoted diboration process to provide 1,2-diboration products.

Recommanded Product: Methyl 3-phenylpropionate. Welcome to talk about 103-25-3, If you have any questions, you can contact Wang, XX; Li, L; Gong, TJ; Xiao, B; Lu, X; Fuo, Y or send Email.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Aldehyde effect and ligand discovery in Ru-catalyzed dehydrogenative cross-coupling of alcohols to esters WOS:000460683700012 published article about ACCEPTORLESS DEHYDROGENATION; ALIPHATIC-ALCOHOLS; COMPLEXES; OXIDATION; ESTERIFICATION in [Jiang, Xiaolin; Zhao, Dongmei] Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China; [Jiang, Xiaolin; Zhang, Jiahui; Li, Yuehui] Chinese Acad Sci, State Key Lab Oxo Synth & Select Oxidat, Lanzhou Inst Chem Phys, Suzhou Res Inst LICP, Lanzhou 730000, Peoples R China; [Zhang, Jiahui] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450001, Henan, Peoples R China in 2019.0, Cited 25.0. Category: esters-buliding-blocks. The Name is Methyl 3-phenylpropionate. Through research, I have a further understanding and discovery of 103-25-3

The presence of different aldehydes is found to have a significant influence on the catalytic performance when using PN(H)P type ligands for dehydrogenation of alcohols. Accordingly, hybrid multi-dentate ligands were discovered based on an oxygen-transfer alkylation of PNP ligands by aldehydes. The relevant Ru-PNN(PO) system provided the desired unsymmetrical esters in good yields via acceptorless dehydrogenation of alcohols. Hydrogen bonding interactions between the phosphine oxide moieties and alcohol substrates likely assisted the observed high chemoselectivity.

Category: esters-buliding-blocks. Bye, fridends, I hope you can learn more about C10H12O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2020.0 CHEM COMMUN published article about CROSS-COUPLING REACTIONS; SELECTIVE SYNTHESIS; ALKENYL; EFFICIENT; ALKYNES; ROBUST in [Wei, Yi-Ming; Ma, Xiao-Di; Wang, Lei; Duan, Xin-Fang] Beijing Normal Univ, Coll Chem, Beijing 100875, Peoples R China in 2020.0, Cited 56.0. The Name is Methyl 3-phenylpropionate. Through research, I have a further understanding and discovery of 103-25-3. Category: esters-buliding-blocks

The stereospecific Fe-catalyzed arylation of enol tosylates was reported. Various tri- or tetrasubstituted Z or E-enol tosylates of beta-keto esters were arylated using common and Knochel-type Grignard reagents with complete stereofidelity. The precursors for Z/E-zimelidine, tamoxifen and other bioactive compounds were facilely prepared without precious and toxic transition metals.

Category: esters-buliding-blocks. About Methyl 3-phenylpropionate, If you have any questions, you can contact Wei, YM; Ma, XD; Wang, L; Duan, XF or concate me.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Category: esters-buliding-blocks. I found the field of Chemistry very interesting. Saw the article Metal-Free Synthesis of Polysubstituted Imidazolinone Through Cyclization of Amidines with 2-Substituted Acrylates published in 2020.0, Reprint Addresses Shi, M (corresponding author), East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Meilong Rd 130, Shanghai 200237, Peoples R China.; Shi, M (corresponding author), East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Meilong Rd 130, Shanghai 200237, Peoples R China.; Shi, M (corresponding author), Univ Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Chinese Acad Sci,Ctr Excellence Mol Synth, 345 Lingling Rd, Shanghai 200032, Peoples R China.. The CAS is 103-25-3. Through research, I have a further understanding and discovery of Methyl 3-phenylpropionate.

Polysubstituted imidazolinones were synthesized in a facile metal-free cascade nucleophilic cyclization of easily available amidines and 2-substituted acrylates. This protocol is distinguished by simple, mild, and catalyst-free reaction conditions with a broad substrate scope, affording the desired products in moderate to good yields and providing an efficient strategy for synthesis of polysubstituted imidazolinone.

Category: esters-buliding-blocks. Welcome to talk about 103-25-3, If you have any questions, you can contact Liu, Z; Zhang, YS; Wei, Y; Shi, M or send Email.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Ni-catalyzed direct alcoholysis of N-acylpyrrole-type tertiary amides under mild conditions WOS:000516508500001 published article about CROSS-COUPLINGS; ENANTIOSELECTIVE ADDITION; ESTERIFICATION; ACTIVATION; CONVERSION; REAGENTS; ALKENES in [Chen, Hang; Chen, Dong-Huang; Huang, Pei-Qiang] Xiamen Univ, Coll Chem & Chem Engn, Collaborat Innovat Ctr Chem Ene Mat, Dept Chem,Fujian Prov Key Lab Chem Biol, Xiamen 361005, Peoples R China in 2020.0, Cited 50.0. Recommanded Product: 103-25-3. The Name is Methyl 3-phenylpropionate. Through research, I have a further understanding and discovery of 103-25-3

N-Acylpyrrole-type amides are a class of versatile building blocks in asymmetric synthesis. We report that by employing Ni(COD)(2)/2,2 ‘-bipyridine (5 mol%) catalytic system, the direct, catalytic alcoholysis of N-acylpyrrole-type aromatic and aliphatic amides with both primary and secondary alcohols can be achieved efficiently under very mild conditions (rt, 1 h) even at gram scale. By increasing the catalyst loading to 10 mol%, prolonging reaction time (18 h), and/or elevating reaction temperature to 50 degrees C/80 degrees C, the reaction could be extended to both complex and hindered N-acylpyrroles as well as to N-acylpyrazoles, Nacylindoles, and to other (functionalized) primary and secondary alcohols. In all cases, only 1.5 equiv. of alcohol were used. The value of the method has been demonstrated by the racemization-free, catalytic alcoholysis of chiral amides yielded from other asymmetric methodologies.

About Methyl 3-phenylpropionate, If you have any questions, you can contact Chen, H; Chen, DH; Huang, PQ or concate me.. Recommanded Product: 103-25-3

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics