Category: 10287-53-3

Vervliet, Philippe published the artcileIdentification of chemicals leaching from dental resin-based materials after in vitro chemical and salivary degradation, Synthetic Route of 10287-53-3, the publication is Dental Materials (2022), 38(1), 19-32, database is CAplus and MEDLINE.

Only little is known about degradation of methacrylate monomers. Therefore, using in vitro chem. and saliva degradation this study aimed to identify the degradation products of organic compounds present in resin-based dental materials. Ten dental monomers and nine polymerized dental resin-based materials were immersed for 24 h in chem. media (0.1 M HCl, 0.1 M NaOH) and human pooled saliva in order to identify leached monomers and degradation products from chem. and saliva degradation Samples were analyzed using liquid chromatog. coupled to high-resolution mass spectrometry to identify previously unknown degradation products. During in vitro chem. degradation, uncured monomers were rapidly hydrolyzed into mono- and demethacrylated degradation products. During chem. degradation in alk. conditions of polymerized materials, considered the worst-case scenario, only degradation products could be detected. In acidic conditions, monomers and their degradation products were detected. In addition, different additives such as EDMAB, DMPA and HMBP were present in acidic degradation samples. Degradation in human pooled saliva for 24 h to mimic the in vivo situation, resulted in the identification of both monomers and their degradation products. Using state-of-the-art high-resolution mass spectrometry previously unknown degradation products of commonly used monomers were identified for the first time. Patients may be exposed to monomers and their degradation products in the first 24 h after restorative procedures. The results provide a base for further research on the degradation of resin-based dental composites in order to assess their safety using elution and toxicity studies.

Dental Materials published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C3H6O2, Synthetic Route of 10287-53-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Perez-Mondragon, Alma Antonia published the artcileAdhesive resins with high shelf-life stability based on tetra unsaturated monomers with tertiary amines moieties, Product Details of C11H15NO2, the publication is Polymers (Basel, Switzerland) (2021), 13(12), 1944, database is CAplus and MEDLINE.

This work reports the use of two monomers with two tertiary amines and four methacrylic (TTME) or acrylic (TTAC) terminal groups as co-initiators in the formulation of exptl. resin adhesive systems. Both monomers were characterized by FT-IR and ¹H NMR spectroscopies. The control adhesive was formulated with BisGMA, TEGDMA, HEMA, and the binary system CQ-EDAB as a photo-initiator system. For the exptl. adhesives, the EDAB was completely replaced for the TTME or the TTAC monomers. The adhesives formulated with TTME or TTAC monomers achieved double bond conversion values close to 75%. Regarding the polymerization rate, materials formulated with TTME or TTAC achieved lower values than the material formulated with EDAB, giving them high shelf-life stability. The degree of conversion after shelf simulation was only reduced for the EDAB material. Ultimate tensile strength, translucency parameter, and micro-tensile bond strength to dentin were similar for control and exptl. adhesive resins. Due to their characteristics, TTME and TTAC monomers are potentially useful in the formulation of photopolymerizable resins for dental use with high shelf-life stability.

Polymers (Basel, Switzerland) published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Product Details of C11H15NO2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Pereira, Leonardo Duarte Eiras published the artcileInfluence of resin matrix on the rheology, translucency, and curing potential of experimental flowable composites for bulk-fill applications, Synthetic Route of 10287-53-3, the publication is Dental Materials (2021), 37(6), 1046-1053, database is CAplus and MEDLINE.

To propose monomer formulations that show an optimal degree of conversion as a function of depth for bulk-fill applications.Four resin blends were formulated with methacrylate-based monomers: BisGMA + TEGDMA (control); BisEMA + BisGMA + TEGDMA (BisEMA-based); UDMA + BisGMA + TEGDMA (UDMA-based) and BisEMA + UDMA + BisGMA + TEGDMA (BisEMA + UDMA-based). For each material, a photoinitiating system and silanized filler particles were added. The rheol. analyses were performed with a rotational rheometer using the cone/plate geometry. CIELab coordinates were assessed over black and white backgrounds using a bench spectrophotometer (SP60, X-Rite) to calculate the translucency parameter (TP) for samples with 0.5, 4, and 6 mm thickness. The degree of C = C conversion (DC) was determined by IR spectroscopy (FTIR/ATR) at 0.05 mm (top), 4, and 6 mm depths (bottom), and the bottom-to-top ratio was considered. A broad spectrum-based LED was used for light activation. Anal. of variance and Tukey′s test (95%) were performed on the results.The materials tested showed pseudoplastic and thixotropic behavior and a predominance of viscous effects over elastics. The control resin yielded the lowest viscosity for the entire shear rate investigated, followed by the BisEMA-based, BisEMA + UDMA-based, and UDMA-based group, which had the highest viscosity. The UDMA-based material showed the lowest TP as a function of thickness. Both the materials′ formulations and depths significantly influenced the DC. The UDMA-based group promoted the highest DC on the top (71 ± 1%) and 4 mm depth (68 ± 1%) but exhibited lower bottom-to-top DC ratio. The BisEMA + UDMA-based material promoted the highest bottom-to-top DC ratio at 4 mm (99%) and 6 mm (97%). The resin matrix interferes in the rheol. behavior, translucency parameter, and polymerization capacity as a function of depth. The material formulated with the addition of UDMA and BisEMA demonstrated the highest curing potential as a function of depth and can be useful for bulk-fill applications.

Dental Materials published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Synthetic Route of 10287-53-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Fugolin, A. P. P. published the artcileProbing stress relaxation behavior in glassy methacrylate networks containing thio-carbamate additives, Product Details of C11H15NO2, the publication is Journal of Materials Chemistry B: Materials for Biology and Medicine (2021), 9(13), 3015-3024, database is CAplus and MEDLINE.

The incorporation of thiourethane prepolymer (TU) into either the organic phase or as a surface treatment for filler particles in composites reduces polymerization stress and improves fracture toughness. The aim of this study was to gain insight into the influence of the inclusion of thiourethanes on the resulting network of methacrylate-based materials polymerized via free-radical mechanisms. Dynamic mech. anal. was used to elucidate network parameters and potential stress relaxation behavior of these networks. TU oligomers were synthesized using a combination of trimethylol-tris-3-mercaptopropionate and dicyclohexylmethane 4,4′-diisocyanate and added into composite formulations at 20 wt% replacing part of the organic matrix and/or as TU-silanes used to functionalize filler particles (TU-matrix, TU-Sil or TU-matrix/sil). Materials not containing any form of TU were used as the control (in those cases, 3-(trimethoxysilyl)propyl methacrylate was used as the silane agent). Filler was added at 50 wt%. Degree of conversion was evaluated by near-IR spectroscopy, mech. properties by 3-point bending and rotational rheometry. Dynamic mech. anal. was used to obtain network parameters (glass transition temperature (T_g), storage modulus, crosslink d., and breadth of tan delta a proxy for network homogeneity – temperature sweep experiments) and to evaluate the potential for network relaxation (stress relaxation). TU-containing formulations showed 10% higher DC than the control. The time to reach storage/loss modulus crossover in the rheometer experiments was significantly longer for TU-matrix and TU-matrix/sil in comparison with the control (21.6, 27.9, and 5.1 s, resp.). TU-matrix and TU-matrix/sil presented significant lower T_g than the control (151.5, 153.8, and 161.3°C, resp.). There were no statistical differences among the groups in terms of shear modulus, crosslink d., breadth of tan delta, flexural strength/modulus, and toughness. For at least one group (TU-matrix/sil), the relaxation time was four times faster than for the control at 105°C. The addition of TU additives into dental polymers resulted in a stark reduction in the stress relaxation time. This behavior, in tandem with the network characterization and mech. properties seems to indicate the TU networks undergo a variety of reversible associative and dissociative chem. reactions which facilitate enhanced stress relief.

Journal of Materials Chemistry B: Materials for Biology and Medicine published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Product Details of C11H15NO2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chen, Hongyan published the artcileSize-controllable synthesis of dendritic porous silica as reinforcing fillers for dental composites, Recommanded Product: Ethyl 4-dimethylaminobenzoate, the publication is Dental Materials (2021), 37(6), 961-971, database is CAplus and MEDLINE.

Porous materials, especially porous silica particles are of great interest in different areas, and have applied in dental composites as inorganic fillers, due to their potential in constructing micromech. interlocking at the filler-resin matrix interfaces. However, the facile and precise synthesis of hierarchical porous silica with graded sizes is still a great challenge.Here, we synthesized dendritic porous silica (DPS) with center-radial hierarchical pores and controllable size ranging from 75 to 1000 nm by varying simultaneously the amounts of silica precursor and template in the microemulsion. A plausible nucleation-growth mechanism for the structural formation and the size tunability of the DPS particles was further put forward. These DPS particles were then formulated with Bis-GMA/TEGDMA resin.The particle size and morphol. influenced the mech. properties of dental composites. Particularly, DPS-500 particles (average size: 500 nm) exhibited the superior reinforcing effect, giving large improvements of 32.0, 96.7, 51.9, and 225.6% for flexural strength (SF), flexural modulus (EY), compressive strength (SC), and work of fracture (WOF), resp., over the DPS-75 filled composite. All DPS filler sized exhibited similar degree of conversions and curing depths. Furthermore, the DPS-500 filled composite presented better cytocompatibility than com. Z250 XT.The facile synthesis of DPS particles developed here and the understanding of the influence of the filler size and morphol. on the composite properties provide a shortcut to design porous silica with precise size control and dental composites with superior performance. These DPS particles could also have promising applications in biomedicine, catalysis, adsorption, and cancer therapy.

Dental Materials published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Recommanded Product: Ethyl 4-dimethylaminobenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chen, Zhi-Feng published the artcileComparison of the ability of UV-Vis and UPLC-Q-TOF-MS combined with chemometrics to discriminate recycled and virgin polyethylene, Recommanded Product: Ethyl 4-dimethylaminobenzoate, the publication is Journal of Hazardous Materials (2022), 423(Part_B), 127165, database is CAplus and MEDLINE.

A growing attention is attracted to the use of recycled plastics as food contact materials, and its chem. safety research and discrimination approach are indispensable. In current study, UV-visible spectrometry (UV-Vis) and ultra-performance liquid chromatog. quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) were used to provide spectral and mass fingerprinting for polyethylene (PE). Coupling with chemometrics, two methods were developed to discriminate recycled and virgin PE. UV-Vis combined with chemometrics could be a more accessible, simpler and faster approach. 237-331 nm in UV spectrum was regarded as marker region selected by orthogonal partial least-squares discrimination anal. (OPLS-DA) and the accuracy of both calibration and validation set could reach 100% in linear discrimination anal. (LDA) based on this region. Besides, 2314 ions were detected by UPLC-Q-TOF-MS and processed by MS-DIAL. 48 candidate chems. were identified, including ketone, esters, carboxylic acid, alcs. and phenols, amine, nitriles, aldehydes and others. Possible origins of these compounds could be classified as plastic, food, drug, cosmetics and pesticide related. Many of these compounds are highly toxic, especially pesticide related, indicating that recycling in closed loop or sorting by the recycled plastic articles is very necessary if the recycled PE is going to be used as food contact material.

Journal of Hazardous Materials published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Recommanded Product: Ethyl 4-dimethylaminobenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wang, Rong published the artcileMethacrylate-functionalized proanthocyanidins as novel polymerizable collagen crosslinkers – Part 2: Effects on polymerization, microhardness and leaching of adhesives, Category: esters-buliding-blocks, the publication is Dental Materials (2021), 37(7), 1193-1201, database is CAplus and MEDLINE.

The aim of the study was to investigate the effects of a novel polymerizable collagen crosslinker methacrylate-functionalized proanthocyanidins (MAPA) on the polymerization, microhardness and leaching of a HEMA-based exptl. dental adhesive system.Three MAPAs were synthesized using different methacrylate (MA) to proanthocyanidins (PA) feeding ratios of 1:2, 1:1, and 2:1 to obtain MAPA-1, MAPA-2, and MAPA-3, resp. The resulting three MAPAs and PA were added to an exptl. adhesive formulated with HEMA and a tri-component photoinitiator system (0.5 wt% CQ/EDMAB/DPIHP) at 1%, 5% and 10% MAPA or PA concentrations (wt%). The adhesive polymerization kinetics was measured continuously in real-time for 10 min using a Fourier-transform IR spectroscopy (FTIR) with an attenuated total reflectance (ATR) accessory. Degree of conversion (DC) and Vickers microhardness (MH) of cured adhesives were measured at 72 h post-cure. The leaching of cured adhesives in DI water was monitored using UV-vis spectrophotometer. Statistical anal. was performed using one-way and two-way ANOVA, Tukey’s (p < 0.05).The adhesive formulations with 1%, 5% and 10% MAPAs-1, -2, -3 all generated higher rate of polymerization and 10-min DC than the formulations with PA at the same concentrations At 72 h post-cure, the adhesive formulation with 5% MAPA-2 exhibited significantly higher DC (99.40%) and more than doubled MH (18.93) values than the formulation with 5% PA (DC = 89.47%, MH = 8.41) and the control (DC = 95.46%, MH = 9.33). Moreover, the cured adhesive with 5% MAPA-2 demonstrated significantly reduced PA leaching in comparison with cured adhesive with 5% PA.Synthesized MAPA is a novel class of polymerizable collagen crosslinker that not only stabilizes dentin collagen via its PA component, but also improves polymerization, mech. properties and stability of HEMA-based adhesives via its MA component. By inheriting the benefit while overcoming the drawback of PA, MAPA offers a revolutionary solution for improved bond-strength and longevity of dental restorations.

Dental Materials published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C14H14, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wu, YinPing published the artcileStudy on bifunctional acyldiphenylphosphine oxides photoinitiator for free radical polymerization, Synthetic Route of 10287-53-3, the publication is European Polymer Journal (2022), 111093, database is CAplus.

Three novel bifunctional acylphosphineoxide compounds containing diallyl amino group were designed and synthesized as photoinitiators for free radical photopolymerization (FRP) of acrylates. Firstly, the photoinitiation properties of DABPOs (DABPO-1, DABPO-2 and DABPO-3), including their UV-vis spectra, the migration after curing and the solubility in monomers, have been studied and compared with com. photoinitiator 2,4,6-trimethyl(phenyl)diphenyl oxide (TPO). The results show that DABPOs have the red-shift absorption wavelength, higher molar absorption coefficient, lower migration and higher solubility comparing with TPO, and they have higher double bond conversion (DC) in TMPTA monomer than TPO under the exposure of 420 nm. Secondly, DABPOs have been successfully used as co-initiator in H-extraction photocuring system. The results show that diallyl amino acylphosphine oxides are effective bifunctional photoinitiators for photopolymerization under LED irradiation

European Polymer Journal published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C19H18O2, Synthetic Route of 10287-53-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

de Oliveira, Naiara Araujo published the artcile1,3,5-triacryloylhexahydro-1,3,5-triazine improves antibacterial and physicochemical properties of an experimental resin-based cement, Computed Properties of 10287-53-3, the publication is International Journal of Adhesion and Adhesives (2022), 117(Part_A), 103157, database is CAplus.

Stable antibacterial cement could contribute to reducing the biofilm formation for a healthy marginal sealing in high-risk areas in indirect restorations. This study aimed to incorporate 1,3,5-triacryloylhexahydro-1,3,5-triazine (TAT) on exptl. resin-based cements and evaluate its antibacterial and physicochem. properties. An exptl. resin-based cement was formulated with 50 wt% Bisphenol A-Glycidyl Methacrylate (BisGMA), 30 wt% Urethane Dimethacrylate (UDMA), 20 wt% Triethylene Glycol Dimethacrylate (TEGDMA), and initiators. Barium silicate glass was used as a filler (45 wt%) and two different groups were tested: CTAT with 15 wt% TAT addition and CCONTROL with no TAT addition The developed cements were evaluated by their degree of conversion, film thickness, flow, flexural strength, softening solvent, cytotoxicity, and antibacterial activity. Microshear bond strength (μSBS) was evaluated regarding dental tissues, glass-ceramics, and polycrystalline ceramics. CTAT showed a higher degree of conversion, lower cytotoxicity, lower softening solvent, and an increased film thickness when compared to CCONTROL. No statistical difference was found between the groups for flow, flexural strength, planktonic antibacterial anal., and cytotoxicity. Reduced biofilm formation was observed in the CTAT group. CTAT improved the μ SBS values for a polycrystalline ceramic substrate. The addition of 1,3,5-triacryloylhexahydro-1,3,5-triazine showed anti-biofilm activity, increased degree of conversion, decreased cytotoxicity, and increased bond strength for IPS-YTZP substrate tested.

International Journal of Adhesion and Adhesives published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Computed Properties of 10287-53-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Lin, Jui-Teng published the artcileEfficacy modeling of new multi-functional benzophenone-based system for free-radical/cationic hybrid-photopolymerization using 405 nm LED, Synthetic Route of 10287-53-3, the publication is Journal of Polymer Research (2022), 29(3), 100, database is CAplus.

This article presents, for the first time, the kinetics and the general conversion features of a 3-component system, benzophenone-triphenylamine(BT)/iodonium/Amine, based on proposed mechanism of Liu et al., for both free radical polymerization (FRP) of acrylates and the free radical promoted cationic polymerization (CP) of epoxides using the new multi-functional initiator of BT. The additives, iodonium and amine, Et 4-(dimethylamino)benzoate (EDB), have the dual function of (i) regeneration BT and (ii) produce of extra radicals for improved FRP and CP. Analytic formulas are developed to explore the new features including: (i) the conversion efficacy (CE) of FRP is an increasing function of the light intensity, the effective absorption coefficient, and the concentration sum of each of the components, BT, Iod, amine, for transient state. However, CE at steady-state is independent to the light intensity; (ii) the trifunctional hybrid structures of BT3 leads to larger light absorption than other types of BT; it also provides more active sites for the H-abstraction in the presence of EDB, leading to high CE; (iii) the efficacy of FRP is an increasing function of the amine (EDB) concentration, in contrast to that of CP having an opposite dependence; (iv) the consumption rate of BT3 in the BT3/Iod/EDB system is slower than that of the BT3/Iod system due to photoredox catalytic cycle, and the larger initiator regeneration (RGE)in the three-component system.

Journal of Polymer Research published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Synthetic Route of 10287-53-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics