Category: 10287-53-3

Garcia, Isadora Martini published the artcileMagnetic motion of superparamagnetic iron oxide nanoparticles- loaded dental adhesives: physicochemical/biological properties, and dentin bonding performance studied through the tooth pulpal pressure model, Related Products of esters-buliding-blocks, the publication is Acta Biomaterialia (2021), 337-347, database is CAplus and MEDLINE.

The limited durability of dentin bonding harshly shortens the lifespan of resin composites restorations. The controlled, dynamic movement of materials through non-contacting forces provides exciting opportunities in adhesive dentistry. We, herein, describe comprehensive investigations of a new dental adhesive with superparamagnetic iron oxide nanoparticles (SPIONs) sensitive to magnetic fields for bonding optimization. This contribution outlines a roadmap of (1) designing and tuning of an adhesive formulation containing SPIONs to enhance penetrability into etched dentin guided by magnetic-field; (2) employing a clin. relevant model of simulated hydrostatic pulpal pressure on the microtensile bond to dentin; and (3) investigating a potential antibacterial effect of the formulated adhesives, and their biocompatibility. SPION-concentration-dependency chem. and mech. behavior was shown via the degree of conversion, ultimate tensile strength, and micro shear bond strength to dentin. The effects of SPIONs carried on a dental adhesive on the bonding strength to dentin are studied in depth by combining experiments with in vitro simulated model. The results show that under the guided magnetic field, 0.07 weight% of SPIONs-doped adhesive increased the bond strength that surpasses the reduction caused by hydrostatic pulpal pressure. Using a magnetic guide workflow during the bonding procedures, SPIONs-doped adhesives improved dentin′s adhesion without changing adhesives′ physicochem. properties. This outcome addresses the key challenge of poor resin infiltration of dentin′s conventional total etching during the bonding procedure. The real-time magnetic motion of dental adhesives may open new paths to enhance resin-based restorations′ longevity. In this study, dental adhesives containing superparamagnetic iron oxide nanoparticles (SPIONs) were developed to enhance penetrability into dentin guided by a magnetic field. The adhesives were screened for phys., chem., antibacterial properties, and cytotoxicity. For the first time, simulated pulpal pressure was used concurrently with the magnetic field to simulate a clin. setting. This approach showed that it is feasible to overcome pulpal pressure jeopardization on bond strength when SPIONs and a magnetic field are applied. The magnetic-responsive adhesives had great potential to improve bond strength, opening new paths to enhance resin-based restorations′ longevity without affecting adhesives′ biol. properties. The use of magnetic-responsive particles and magnetically assisted motion is a promising strategy to improve the sealing ability of dental adhesives.

Acta Biomaterialia published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Alhenaki, Aasem M. published the artcileDentin bond integrity of filled and unfilled resin adhesive enhanced with silica nanoparticles-an SEM, EDX, micro-Raman, FTIR and Micro-tensile bond strength study, Application of Ethyl 4-dimethylaminobenzoate, the publication is Polymers (Basel, Switzerland) (2021), 13(7), 1093, database is CAplus and MEDLINE.

The objective of this study was to synthesize and assess unfilled and filled (silica nanoparticles) dentin adhesive polymer. Methods encompassing SEM (SEM)-namely, energy dispersive X-ray spectroscopy (EDX), micro-tensile bond strength (μTBS) test, Fourier transform IR (FTIR), and micro-Raman spectroscopy-were utilized to investigate Si particles’ shape and incorporation, dentin bond toughness, degree of conversion (DC), and adhesive-dentin interaction. The Si particles were incorporated in the exptl. adhesive (EA) at 0, 5, 10, and 15 weight% to yield Si-EA-0% (neg. control group), Si-EA-5%, Si-EA-10%, and Si-EA-15% groups, resp. Teeth were set to form bonded samples using adhesives in four groups for μTBS testing, with and without aging. Si particles were spherical shaped and resin tags having standard penetrations were detected on SEM micrographs. The EDX anal. confirmed the occurrence of Si in the adhesive groups (maximum in the Si-EA-15% group). Micro-Raman spectroscopy revealed the presence of characteristic peaks at 638, 802, and 1300 cm^-1 for the Si particles. The μTBS test revealed the highest mean values for Si-EA-15% followed by Si-EA-10%. The greatest DC was appreciated for the control group trailed by the Si-EA-5% group. The addition of Si particles of 15 and 10 weight% in dentin adhesive showed improved bond strength. The addition of 15 weight% resulted in a bond strength that was superior to all other groups. The Si-EA-15% group demonstrated acceptable DC, suitable dentin interaction, and resin tag formation.

Polymers (Basel, Switzerland) published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Application of Ethyl 4-dimethylaminobenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chen, Gong published the artcileDirhodium-Catalyzed Chemo- and Site-Selective C-H Amidation of N,N-Dialkylanilines, Safety of Ethyl 4-dimethylaminobenzoate, the publication is Synlett (2021), 32(7), 728-732, database is CAplus.

A method for dirhodium-catalyzed C(sp³)-H amidation of N,N-dimethylanilines was developed. Chemoselective C(sp³)^–H amidation of N-Me group proceeded exclusively in the presence of C(sp²)-H bonds of the electron-rich aromatic ring. Site-selective C(sp³)-H amidation proceeded exclusively at the N-Me group of N-methyl-N-alkylaniline derivatives with secondary, tertiary, and benzylic C(sp³)-H bonds α to a nitrogen atom.

Synlett published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Safety of Ethyl 4-dimethylaminobenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Lewis, S. H. published the artcileEffects of systematically varied thiourethane-functionalized filler concentration on polymerization behavior and relevant clinical properties of dental composites, Product Details of C11H15NO2, the publication is Materials & Design (2021), 109249, database is CAplus and MEDLINE.

Introduction of thiourethane (TU) oligomer to resin-based dental restorative materials reduces stress and improves fracture toughness without compromising conversion. Localization of TU at the resin-filler interface via silanization procedures may lead to more substantial stress reduction and clin. property enhancements. The objective of this study was to evaluate composite properties as a function of TU-functionalized filler concentration TU oligomers were synthesized using click-chem. techniques and subsequently silanized to barium glass filler. Resin-based composites were formulated using varying ratios of TU-functionalized filler and conventional methacrylate-silanized barium filler. Material property testing included thermogravimetric anal., real-time polymerization kinetics and depth of cure, polymerization stress, stress relaxation and fracture toughness. Clin. property testing included water sorption/solubility, composite paste viscosity, and gloss and surface roughness measured before and after subjecting the samples to 6 h of continuous tooth brushing in a custom-built apparatus using a toothpaste/water mixture Increasing TU-filler in the composite resulted in as much as a 78% reduction in stress, coupled with an increase in fracture toughness. Conversion was similar for all groups. After simulated tooth brushing, gloss reduction was lower for TU-containing composites and surface roughness was less than or equal to the control.

Materials & Design published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Product Details of C11H15NO2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Catel, Yohann published the artcileHigh refractive index monofunctional monomers as promising diluents for dental composites, COA of Formula: C11H15NO2, the publication is Dental Materials (2021), 37(2), 351-358, database is CAplus and MEDLINE.

To evaluate high refractive index methacrylates as diluents for the formulation of radiopaque esthetic bulk-fill composites.2-(4-Cumylphenoxy)ethyl methacrylate 1, 2-(2-phenylphenoxy)ethyl methacrylate 2 and 2-[2-(2-phenylphenoxy)ethoxy]ethyl methacrylate 3 were synthesized and characterized by ¹H NMR spectroscopy. The reactivity of each monomer was studied using photo-DSC. Bulk-fill composites based on monomers 1-3 were formulated. Translucency (before and after light cure) was measured using a spectrophotometer. The depth of cure and the water sorption of these materials were determined according to ISO 4049. The flexural strength and modulus of elasticity were measured using a three-point bending setup, according to ISO 4049. The shrinkage force was assessed based on a method described by Watts et al. using a universal testing machine.Monomers 1-3 were easily synthesized in two steps. They exhibit a low viscosity and a high refractive index (1.553-1.573). Monofunctional methacrylates 1-3 were found to be more reactive than triethylene glycol dimethacrylate (TEGDMA). Bulk-fill composites based on these monomers were successfully prepared They exhibit a high depth of cure and excellent esthetic properties (low transparency). These composites provide higher flexural modulus as well as lower water sorption than a corresponding material based on TEGDMA. Methacrylates 1 and 3 are particularly interesting as they led to composites showing lower shrinkage force.Methacrylates 1-3 are promising diluents for the formulation of highly esthetic radiopaque bulk-fill composites.

Dental Materials published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, COA of Formula: C11H15NO2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Mitwalli, Heba published the artcileNovel rechargeable calcium fluoride dental nanocomposites, Recommanded Product: Ethyl 4-dimethylaminobenzoate, the publication is Dental Materials (2022), 38(2), 397-408, database is CAplus and MEDLINE.

Composite restorations with calcium fluoride nanoparticles (nCaF2) can remineralize tooth structure through F and Ca ion release. However, the persistence of ion release is limited. The objectives for this study were to achieve long-term remineralization by developing a rechargeable nCaF2 nanocomposite and investigating the F and Ca recharge and re-release capabilities.Three nCaF2 nanocomposites were formulated: (1) BT-nCaF2:Bisphenol A glycidyl dimethacrylate (BisGMA) and triethylene glycol dimethacrylate (TEGDMA); (2) PE-nCaF2:Pyromellitic glycerol dimethacrylate (PMGDM) and ethoxylated bisphenol A dimethacrylate (EBPADMA); (3) BTM-nCaF2:BisGMA, TEGDMA, and Bis[2-(methacryloyloxy)ethyl] phosphate (Bis-MEP). All formulations contained 15% nCaF2 and 55% glass particles. Initial flexural strength and elastic modulus, F and Ca ion release, recharge and re-release were tested and compared to three com. fluoride-containing materials.BT and BTM nCaF2 composites were 3-4 times stronger and had elastic modulus 2 times that of resin-modified glass ionomer controls. PE-nCaF2 had comparable strength to RMGIs. All nCaF2 composites had significant F and Ca ion release and ion rechargeability. In F and Ca recharging cycles, PE-nCaF2 had the highest ion recharging capability among nCaF2 groups, followed by BT-nCaF2 and BTM-nCaF2 (p < 0.05). For all recharge cycles, ion release maintained similar levels, demonstrating long-term ion release was possible. Furthermore, after the final recharge cycle, nCaF2 nanocomposites provided continuous ion release for 42 days without further recharge.Novel nCaF2 rechargeable nanocomposites exhibited significant F and Ca ion release over multiple recharge cycles, demonstrating continuous long-term ion release. These nanocomposites are promising restorations with lasting remineralization potential.

Dental Materials published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Recommanded Product: Ethyl 4-dimethylaminobenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chiari, Marina D. S. published the artcileExperimental dentin adhesives containing calcium orthophosphate particles: Effect on dentin bond strength, micro-permeability and collagen degradation, Application of Ethyl 4-dimethylaminobenzoate, the publication is International Journal of Adhesion and Adhesives (2021), 102828, database is CAplus.

To assess the effect of dicalcium phosphate dihydrate (DCPD) or mineral trioxide aggregate (MTA) particles on the microtensile bond strength (ΜTBS), micro-permeability and enzymic activity at the adhesive-dentin interface of exptl. dental adhesives. An exptl. ethanol-based, two-step etch-and-rinse adhesive system was prepared Four exptl. groups were tested, based on the type of particle added: (1) DCPD functionalized with diethylene glycol dimethacrylate (DCPD_DEGDMA), (2) citric acid (DCPD_CA), (3) calcium silicate (MTA) and (4) unfilled (control). All particles were added at 10 wt%. Human third molars had their occlusal enamel removed and dentin surface polished. After acid etching, the adhesives were applied on the dentin surfaces and the teeth were restored with a com. nanofilled resin composite. The μTBS and micro-permeability were tested after 24 h or 2 mo of storage in simulated body fluid (SBF) at 37°C. Bonded interfaces were observed using scanning electron microcopy (SEM). Gelatinolytic activity at the adhesive interfaces was assessed by in situ zymog. at 24 h and 2 mo in SBF/37°C. The results were described as relative florescent units (RFU). μTBS data were analyzed by ANOVA/Games-Howell test. Data from micro-permeability and in situ zymog. were analyzed by Kruskal-Wallis/Mann-Whitney test (alpha: 5%). Differences in μTBS were found among adhesives (control = MTA > DCPD_CA > DCPD_DEGDMA, p < 0.001), but not between storage times. The control group showed the lowest permeability at both observation periods. Except for DCPD_CA, no significant increases in micro-permeability were observed after 2 mo. All groups presented significant reductions in RFU values between 24 h and 2 mo. DCPD_DEGDMA (at 24 h) and MTA (at 2 mo) presented statistically lower RFU than the control (p < 0.01). Evidence of reduced MMP activity was observed at adhesive interfaces with the use of exptl. adhesives containing calcium-releasing particles. However, after two months, bond strength and micro-permeability results suggest that interfacial stability was not affected by adhesive formulation.

International Journal of Adhesion and Adhesives published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Application of Ethyl 4-dimethylaminobenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics