Category: 102-09-0

Germanium Hydride Catalyzed Selective Hydroboration and Cyanosilylation of Ketones was written by Khuntia, Anwesh Prasad;Sarkar, Nabin;Patro, A. Ganesh;Sahoo, Rajata Kumar;Nembenna, Sharanappa. And the article was included in European Journal of Inorganic Chemistry in 2022.Category: esters-buliding-blocks The following contents are mentioned in the article:

Two new examples of β-diketiminate or NacNac analogs, i. e., conjugated bis-guanidinate (CBG) stabilized low valent germanium chloride (1) and germanium hydride (2) complexes, are reported. Deprotonation of LH upon treatment with n-BuLi and an in situ generated LLi further treated with GeCl₂·dioxane afforded LGeCl in 79% yield. Compound 1 reacted with hydride source NaHBEt₃ in toluene, afforded Ge (II) hydride (2) in 76% yield. Both compounds 1 and 2 were characterized by NMR and mass spectroscopic methods. Further, germanium hydride catalyzed hydroboration and cyanosilylation of a wide range of ketones have been investigated. Control reactions suggest hydroboration reactions occurred via insertion and Ge-O/B-H bond metathesis pathways. It is worthy of mentioning that, in the case of hydroboration of ketones, reducible groups such as alkene, alkyne, halide, ester, nitro, and heterocycles were untouched. Furthermore, compound 2 was employed for the reduction of carbonate, formate, and anhydride substrates via the hydroboration technique. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Category: esters-buliding-blocks).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis, Herbicidal Activity, Crop Safety and Soil Degradation of Pyrimidine- and Triazine-Substituted Chlorsulfuron Derivatives was written by Wu, Lei;Gu, Yu-Cheng;Li, Yong-Hong;Zhou, Sha;Wang, Zhong-Wen;Li, Zheng-Ming. And the article was included in Molecules in 2022.HPLC of Formula: 102-09-0 The following contents are mentioned in the article:

In order to obtain sulfonylurea herbicides with good crop safety for both wheat and corn, while maintaining high herbicidal activities, a series of pyrimidine- and triazine-based diethylamino-substituted chlorsulfuron derivatives I [R¹ = Me, MeO, p-tolyl, etc.; R² = CH,N; R³ = H, Me, MeO, Cl] were systematically evaluated. The structures of the synthesized compounds I were confirmed with ¹H NMR, ¹³C NMR and HRMS. The preliminary biol. assay results indicate that the 4,6-disubstituted pyrimidine and triazine derivatives could maintain high herbicidal activity. It was found that the synthesized compounds I could accelerate degradation rates, both in acidic and alk. soil. Especially, in alk. soil, the degradation rate of the target compounds I accelerated more than 22-fold compared to chlorsulfuron. Moreover, most chlorsulfuron analogs I exhibited good crop safety for both wheat and corn at high dosages. This study provided a reference for the further design of new sulfonylurea herbicides I with high herbicidal activity, fast degradation rates and high crop safety. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0HPLC of Formula: 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.HPLC of Formula: 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tyrosine-Reactive Cross-Linker for Probing Protein Three-Dimensional Structures was written by Cui, Lili;Ma, Yongge;Li, Ming;Wei, Zhonglin;Huan, Yanfu;Li, Hongmei;Fei, Qiang;Zheng, Lianyou. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2021.SDS of cas: 102-09-0 The following contents are mentioned in the article:

Crosslinking mass spectrometry (XL-MS) has made significant progress in understanding the structure of protein and elucidating architectures of larger protein complexes. Current XL-MS applications are limited to targeting lysine, glutamic acid, aspartic acid, and cysteine residues. There remains a need for the development of novel cross-linkers enabling selective targeting of other amino acid residues in proteins. Here, a novel simple cross-linker, namely, [4,4′-(disulfanediylbis(ethane-2,1-diyl)) bis(1,2,4-triazolidine-3,5-dione)] (DBB) (I), has been designed, synthesized, and characterized. This cross-linker can react selectively with tyrosine residues in protein through the electrochem. click reaction. The DBB cross-links produced the characteristic peptides before and after electrochem. reduction, thus permitting the simplified data anal. and accurate identification for the cross-linked products. This is the first time a cross-linker is developed for targeting tyrosine residues on protein without using photoirradiation or a metal catalyst. This strategy might potentially be used as a complementary tool for XL-MS to probe protein 3D structures, protein complexes, and protein-protein interaction. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0SDS of cas: 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. SDS of cas: 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Investigation of a new horizon antifungal activity with enhancing the antimicrobial efficacy of ciprofloxacin and its binary mixture via their encapsulation in nanoassemblies: in vitro and in vivo evaluation was written by Abou Taleb, Sally;Darwish, Asmaa Badawy;Abood, Amira;Mohamed, Amany M.. And the article was included in Drug Development Research in 2020.Name: Diphenyl carbonate The following contents are mentioned in the article:

The main goal of this study was to prepare and evaluate nanosponges containing ciprofloxacin (CIP) or its binary mixture with N-acetyl carnosine (NAC). Nanosponges were prepared by ultrasound-assisted synthesis technique using hydroxypropyl βeta-cyclodextrin (HPβ-CD), as the polymer and di-Ph carbonate (DPC) as the crosslinker. Entrapment efficiency (EE%) of CIP or its binary mixture with NAC in nanosponges was deduced spectrophotometrically. Nanosponges were characterized using several methods. EE% of CIP or its binary mixture with NAC inside nanosponges ranged from 98.63 ± 3.1 to 100 ± 0.07%. Particle size of nanosponges ranged from 66.7 to 90.1 nm. Release of drugs from nanosponges was biphasic and the release pattern followed Korsmeyer-Peppas model. Ex vivo and in vivo studies results showed that the antibacterial effect was enhanced with encapsulation of drugs in the nanosponge system. Furthermore, a potent antifungal activity was obtained from all examined formulas against Candida albicans (10231). The study revealed that successful encapsulation of CIP or its binary mixture with NAC in nanosponge formulations has innovated a new promising therapeutic activity for both drugs. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Name: Diphenyl carbonate).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Name: Diphenyl carbonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A paradigm for the efficient synthesis of bio-based polycarbonate with deep eutectic solvents as catalysts by inhibiting the degradation of molecular chains was written by Wang, Weiwei;Yang, Zifeng;Zhang, Yaqin;He, Hongyan;Fang, Wenjuan;Zhang, Zhencai;Xu, Fei. And the article was included in Green Chemistry in 2021.Safety of Diphenyl carbonate The following contents are mentioned in the article:

In this study, an efficient catalytic system composed of deep eutectic solvents (DESs) was developed by adjusting the basicity of hydrogen bond donors (HBDs) to synthesize poly(isosorbide)carbonate (PIC) with high weight average mol. weight (Mw). It was demonstrated that the Mw of PIC prepared by using nearly neutral [EminOH]Cl-2EG was the highest. The results of the transesterification kinetics with different catalysts supported that the transesterification rate was significantly promoted as the basicity of DESs increased but their strong alkalinity inhibited the Mw of PIC. Therefore, the degradation of PIC was investigated to reveal the mechanism of the influence of basicity on the mol. weight of PIC. The strong alkalinity of DESs would cause the depolymerization of the macromol. chains and ultimately limit the mol. weight of the product, proving the exptl. fact that a near-neutral catalyst was more conducive to the Mw of PIC. Finally, a reasonable mechanism of synergistic catalysis was proposed based on 1H NMR spectroscopy, Fourier transform IR spectroscopy (FT-IR) and exptl. results. The metal-free, low-cost, high catalytic activity DES catalyst involved here is a practical candidate for advanced bio-based polycarbonate. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Safety of Diphenyl carbonate).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of Diphenyl carbonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Solubilization and changes of physicochemical properties of baicalin by nano sponge, and toxicity of zebrafish liver was written by Song, Jiawen;Long, Jiaying;Xie, Long;Sun, Qiang;Zhang, Linlin;Chen, Huijuan;Deng, Mao;Li, Xiaofang. And the article was included in Journal of Drug Delivery Science and Technology in 2020.HPLC of Formula: 102-09-0 The following contents are mentioned in the article:

As a new type of drug carrier, nano-sponge (NS) can remarkably improve the solubility of poorly soluble drug components, significantly increase the efficacy of drugs and their bioavailability. Baicalin (BA) has many biol. activities, such as anti-inflammatory, bacteriostatic and , etc. But due to its poor solubility, BA cannot play a role in the clinic. Therefore, it is urgent to find a suitable solubilization technol. to improve the solubility of BA. In this paper, we optimized the preparation process of NS based on β-cyclodextrin (β-CD), and then prepared the baicalin nano-sponges (BA-NS). The successful preparation of BA-NS was verified by modern anal. methods. BA loading capacity and efficiency (BLC and BLE), solubilizing effect, in vitro release rate and liver toxicity were investigated. The results showed that the BLC and BLE were 18.02 ± 0.36% and 86.64 ± 0.86%, solubility in water was 31 times than that of pure BA, and release rate in different media could reach 80%. Zebrafish liver toxicity test showed no obvious toxicity. The above results showed that NS had a significant solubilizing effect on BA and was safe and non-toxic, and proved that NS maybe have broad prospects in the research of poorly soluble drugs. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0HPLC of Formula: 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.HPLC of Formula: 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Reaction kinetics of melt post-polycondensation process for polycarbonate in film state was written by Chen, Mengdi;Bao, Jianna;Zheng, Mingfu;Zhang, Xianming;Chen, Wenxing. And the article was included in Journal of Applied Polymer Science in 2022.Formula: C13H10O3 The following contents are mentioned in the article:

Melt post-polycondensation (MPP) process is one of manufactures industrially that can efficiently increase the mol. weight of polycarbonate (PC). Herein, the MPP experiments of several PC materials using quaternary ammonium hydroxides and alkali metal compounds as the catalyst in the film state are studied. The reaction products are characterized by Ubbelohde viscometer, DSC, ¹H-NMR, UV spectrophotometry, advanced polymer chromatog. and rotational rheometer. It is found that MPP can effectively improve the intrinsic viscosity of PC. After a certain reaction time at a specific temperature, the number average mol. weight (M_n) of PC is raised from 19,000 to 54,600 g/mol. Furthermore, the ¹H-NMR results reveal that Fries rearrangement products are produced during the MPP process. Based on the functional group model, a reaction kinetic model, combining the effects of the main melt polycondensation reaction and the Fries rearrangement reaction, is established for the first time. The reaction rate constants at different temperatures and the reaction activation energies of the two PC materials are obtained. This work provides a new reaction kinetics model to guide the MPP process of PC, which contains Fries rearrangement reaction. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Formula: C13H10O3).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Formula: C13H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Organocatalytic ring-opening polymerization of disulfide functional macrocyclic carbonates: An alternative strategy to enzymatic catalysis was written by Yan, Bingkun;Liang, Bingyu;Hou, Jiaqian;Wei, Chao;Xiao, Yan;Lang, Meidong;Huang, Farong. And the article was included in European Polymer Journal in 2020.Reference of 102-09-0 The following contents are mentioned in the article:

Ring-opening polymerization (ROP) of macrocyclic carbonates (≥12 ring) is still challenging due to the associated low ring-strain. Although organometallic and enzyme based catalysts have been studied, disadvantages such as organometallic residue and enzymic nature limit their applications. After screening com. available organocatalysts, we report the use of organocatalysts for ROP of disulfide-containing macrocyclic carbonates (MSS, 16 ring). It was found that organocatalysts (TBD) presented high active and living ROP of MSS, as evidenced by kinetic studies, yielding main chain disulfide-containing polycarbonates with tailor-made structures and predictable mol. weights with low mol. weight distribution. Copolymerizations with trimethylene carbonate (TMC) generated random copolymers with controlled components, regulating the d. of disulfide functional groups. By comparing with the behaviors of enzyme catalysis in kinetic studies and (co-)polymerization, it is observed that organic catalyzed ROP showed more efficient (∼ ten times faster), milder condition and more controlled behaviors than enzyme catalyzed ROP (N-435). Therefore, we believe this organic catalyzed strategy will provide an alternative to the current enzymic and organometallic catalyst for ROP of macrocyclic carbonates. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Reference of 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Reference of 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Preparation and characterization of novel functional tri-block copolymer for constructing temperature/redox dual-stimuli responsive micelles was written by Liu, Tianyue;Lang, Meidong. And the article was included in Journal of Macromolecular Science in 2022.Electric Literature of C13H10O3 The following contents are mentioned in the article:

Herein, we reported a novel tri-block copolymer synthesized by segmented ring-opening polymerization of temperature-sensitive 5-(pyrrolidine-1-carbonyl) oxepan-2-one monomer (VPyCL) and redox-sensitive macrocyclic disulfide-substituted carbonate monomer (MSS). The structure of the copolymers was confirmed by GPC, 1H NMR and 13C NMR. The obtained tri-block copolymers could self-assemble in aqueous solution to form well-structured micelles, with the mPEG-b-PVPyCL block acting as the hydrophilic coronal and the PSS block acting as the hydrophobic core. Dynamic light scattering (DLS) studies confirmed that micelles formed by these tri-block copolymers with different block ratios could respond to different temperature ranges during the heating/cooling process and respond to reducing agent glutathione (GSH). In addition, transmission electron microscopy (TEM) results further confirmed the polymeric micelles′ dual-stimuli responsiveness. The potential application of this type of dual-stimuli responsive micelles in drug delivery systems was evaluated using doxorubicin (DOX) as the model mol. The stimulus-dependent responsive behaviors of obtained micelles can be applied to the construction of smart materials capable of performing multiple functions under the appropriate conditions. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Electric Literature of C13H10O3).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Electric Literature of C13H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Catalytic hydroboration of carbonyl derivatives by using phosphinimino amide ligated magnesium complexes was written by Li, Min;Liu, Xinli;Cui, Dongmei. And the article was included in Dalton Transactions in 2021.Related Products of 102-09-0 The following contents are mentioned in the article:

Reduction of carbonyl derivatives by using Earth-abundant, cheap, and environmentally benign metal-based catalysts through an atom-efficient method is a challenging task. Herein, authors report the synthesis and characterization of dinuclear magnesium complexes 1–3 chelated by a phosphinimino amide skeleton. In combination with pinacolborane (HBpin) as a reducing agent, complex 1 bearing an ortho-Me substituent on the Ph ring of the ligand showed excellent reduction capability for a broad range of carbonyl derivatives under mild reaction conditions. Aldehydes, ketones, and acrolein substrates were efficiently reduced to the corresponding alkoxy-borane products with a record high TOF. Besides, acrolein derivatives were exclusively reduced to 1,2-regioselective products. Using two equivalent of HBpin, ester substrates were reduced to two kinds of alkoxy-borane products. Carbonate reduction accomplished by using complex 1 and three equivalent of HBpin afforded diols and a methanol precursor, resp. When chiral substrates such as (S)-1,2-propanediol carbonate and L-lactide or polymeric P(L-LA) were employed, the chirality was almost retained in their reductive products. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Related Products of 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Related Products of 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics