Category: 102-09-0

Depolymerization of End-of-Life Poly(bisphenol A carbonate) via 4-Dimethylaminopyridine-Catalyzed Methanolysis was written by Alberti, Christoph;Enthaler, Stephan. And the article was included in Waste and Biomass Valorization in 2020.Application In Synthesis of Diphenyl carbonate The following contents are mentioned in the article:

The chem. recycling, a sequence of depolymerization and polymerization reactions, of end-of-life plastics/polymers can contribute to a sustainable, resource-conserving and environmental-benign society. In this regard, we have set up a protocol for the depolymerization of end-of-life poly(bisphenol A carbonate). In more detail, applying a combination of methanol and catalytic amounts of 4-dimethylaminopyridine (DMAP) end-of-life poly(bisphenol A carbonate) was depolymerized to bisphenol A and di-Me carbonate. With the aid of microwave heating an excellent rate of depolymerization ( > 99%) within short reaction times (5 min) and turnover frequencies up to 1164 h^-1 were achieved. Moreover, it was demonstrated that phenolysis can be applied under optimized reaction conditions resulting in the formation of the mixture bisphenol A and di-Ph carbonate, which can be used for the synthesis of new poly(bisphenol A carbonate). In consequence a closed cycle for poly(bisphenol A carbonate) is feasible. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Application In Synthesis of Diphenyl carbonate).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of Diphenyl carbonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Degree of crosslinking in β-cyclodextrin-based nanosponges and their effect on piperine encapsulation was written by Guineo-Alvarado, Juan;Quilaqueo, Marcela;Hermosilla, Jeyson;Gonzalez, Sofia;Medina, Camila;Rolleri, Aldo;Lim, Loong-Tak;Rubilar, Monica. And the article was included in Food Chemistry in 2021.COA of Formula: C13H10O3 The following contents are mentioned in the article:

Piperine (PIP) is an alkaloid which is potent as a therapeutic agent. However, its applications are restricted by its poor water solubility Nanosponges (NS) derived from polymers are versatile carriers for poor water-soluble substances. The aim of this work was to synthesize β-cyclodextrin NS, by microwave-assisted fusion, for the encapsulation of PIP. Different formulations of NS were synthesized by varying the molar ratio of β-cyclodextrin:diphenyl carbonate (β-CD:DPC; 1:2, 1:6 and 1:10). NS specimens derived from 1:2, 1:6 and 1:10 β-CD:DPC molar ratios exhibited degree of substitution values of 0.345, 0.629 and 0.878, resp. The crystallinity of NS was enhanced by increasing di-Ph carbonate concentration A high degree of crosslinking in the NS increased the loading efficiency due to increased surface area available for bioactive inclusion. This study demonstrated the feasibility of synthesizing NS derived from β-cyclodextrin of high crystallinity for the encapsulation of PIP at high loading capacity. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0COA of Formula: C13H10O3).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.COA of Formula: C13H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cyclodextrin nanosponges inclusion compounds associated with gold nanoparticles for potential application in the photothermal release of melphalan and cytoxan was written by Salazar, Sebastian;Yutronic, Nicolas;Kogan, Marcelo J.;Jara, Paul. And the article was included in International Journal of Molecular Sciences in 2021.Safety of Diphenyl carbonate The following contents are mentioned in the article:

This article describes the synthesis and characterization of β -cyclodextrin-based nanosponges (NS) inclusion compounds (IC) with the anti-tumor drugs melphalan (MPH) and cytoxan (CYT), and the addition of gold nanoparticles (AuNPs) onto both systems, for the potential release of the drugs by means of laser irradiation The NS-MPH and NS-CYT inclusion compounds were characterized using SEM (SEM), X-ray powder diffraction (XRPD), energy dispersive spectroscopy (EDS), thermogravimetric anal. (TGA), UV-Vis, and proton NMR (1H-NMR). Thus, the inclusion of MPH and CYT inside the cavities of NSs was confirmed. The association of AuNPs with the ICs was confirmed by SEM, EDS, TEM, and UV-Vis. Drug release studies using NSs synthesized with different molar ratios of β -cyclodextrin and diphenylcarbonate (1:4 and 1:8) demonstrated that the ability of NSs to entrap and release the drug mols. depends on the crosslinking between the cyclodextrin monomers. Finally, irradiation assays using a continuous laser of 532 nm showed that photothermal drug release of both MPH and CYT from the cavities of NSs via plasmonic heating of AuNPs is possible. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Safety of Diphenyl carbonate).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Safety of Diphenyl carbonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Energy harvesting by vitrimer-based moist-electric generators was written by Feng, Zihao;Zhao, Wei;Yang, Zhengxin;Deng, Yi;Yang, Tong;Ni, Yonghao. And the article was included in Journal of Materials Chemistry A in 2022.Computed Properties of C13H10O3 The following contents are mentioned in the article:

Exploitation and utilization of green energy are urgent for the sustainable development of human civilization. In this study, we report a series of novel moist-elec. generators (MEGs) based on a polyhydroxyurethane (PHU) vitrimer for the first time. In sharp contrast to traditional polymer MEGs, vitrimer moist-elec. generators (VMEGs) can provide high and sustained voltage outputs under high temperature and high moisture conditions without structural collapse and decomposition Furthermore, after doping with Ti₃C₂, the resultant VMEG can simultaneously convert energy from both water and the sun to elec. energy, providing continuous power for electronic devices, such as timers, under a natural environment. It is noteworthy that the preparation of VMEGs can be easily scaled up by using PHU/cellulose paper composites. The resultant paper-based VMEGs exhibit high elec. output, while possessing excellent mech. properties, good self-healing ability, and high flexibility and transparency. This study provides a novel strategy to fabricate advanced MEGs, and at the same time opens a novel application for vitrimer materials. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Computed Properties of C13H10O3).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C13H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hydrolytic degradation of isosorbide-based polycarbonates: Effects of terminal groups, additives, and residue catalysts was written by Yan, Shengdi;Wu, Guozhang. And the article was included in Polymer Degradation and Stability in 2021.SDS of cas: 102-09-0 The following contents are mentioned in the article:

The hydrolysis degradation of bisphenol-A polycarbonate (BPA-PC), isosorbide (ISB)-co-1,4-cyclohexanedimethanol (CHDM) polycarbonate (IcC-PC), and BPA-PC/IcC-PC reactive blends were systematically investigated. The terminal hydroxyl groups of BPA-PC, thermally derived chem. structure on IcC-PC chains, and derivatives from phosphite antioxidants trigger severe hydrolysis degradation 1H-NMR anal. shows that carbonate groups connected to the BPA unit are most susceptible to hydrolysis, followed by ISB and CHDM units, demonstrating that the acidity of monomers plays a key role in the hydrolysis degradation of polycarbonates. Residual catalysts may cause significant hydrolysis in BPA-PC/IcC-PC reactive blends. Hydrolysis prefers to occur on the exo position of ISB unit with a low steric hindrance rather than on the endo position with a high electrophilicity, indicating that the residual catalyst acts as a Lewis acid and likely promotes hydrolysis through coordination mechanism. The hydrolysis resistance of BPA-PC/IcC-PC blends with a Na-based catalyst is lower than that of blends with K- and Cs-based catalysts because of the strong coordination ability. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0SDS of cas: 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.SDS of cas: 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Amphiphilic methoxy poly(ethylene glycol)-b-poly(carbonate-selenide) with enhanced ROS responsiveness: Facile synthesis and oxidation process was written by Li, Siqi;Song, Fangqin;Sun, Chuanhao;Hu, Jieni;Zhang, Yan. And the article was included in European Polymer Journal in 2021.Electric Literature of C13H10O3 The following contents are mentioned in the article:

The synthesis of ROS-responsive polymers has attracted much attentions in recent years. Herein, we report a series of amphiphilic methoxy poly(ethylene glycol)-b-poly(carbonate-selenide)s (mPEG₄₅-b-poly(MSe)_m, m = 12, 24, 36, 48, 60) by introducing selenide groups onto the backbone via one-pot lipase-catalyzed ring-opening polymerization (ROP), the synthesized amphiphilic polymers with enhanced ROS-responsiveness can self-assemble to form nanoparticles. NMR, Gel Permeation Chromatog. and Fourier Transform IR are employed to confirm the structure of the polymers. Besides, the oxidation process of mPEG₄₅-b-poly(MSe)_m nanoparticles is also clarified. UV-visible Spectrophotometer, Dynamic Light Scattering and Transmission Electron Microscopy are further utilized to demonstrate the turbidity, morphol. and size changes under oxidization, proving that the selenide groups endow the mPEG₄₅-b-poly(MSe)_m nanoparticles with enhanced ROS-response properties. Therefore, the above studies highlight the synthesized ROS-responsive polymers and provided a potential material for further applications. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Electric Literature of C13H10O3).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Electric Literature of C13H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Evaluation of EDTA Dianhydride Versus Diphenyl Carbonate Nanosponges for Curcumin was written by Mashaqbeh, Hadeia;Obaidat, Rana;Al-shar’i, Nizar A.. And the article was included in AAPS PharmSciTech in 2022.SDS of cas: 102-09-0 The following contents are mentioned in the article:

Cyclodextrin-based nanosponges are widely investigated for several applications and are considered potential drug carriers. The method of nanosponges preparation involves the use of chem. crosslinking agents where the properties of Nanosponges can be affected. This study compared the resulting differences in the final nanosponges’ properties using carbonate and dianhydride crosslinkers. Di-Ph carbonate and EDTA dianhydride were used for the synthesis of nanosponges. Both types of nanosponges were loaded with curcumin as a model drug. Physicochem. characterizations, including PXRD, DSC, FTIR, SEM, AFM, particle size, zeta potential, and surface area anal., were carried out for the prepared nanosponges. Curcumin release and drug content were also evaluated. Nanosponges prepared by Di-Ph carbonate crosslinker resulted in an amorphous form compared to crystalline EDTA-nanosponges. This study reported the successful inclusion and complexation of curcumin inside carbonate cross-linked cyclodextrin-based nanosponges and suggested the phys. entrapment of crystalline curcumin in EDTA dianhydride. These findings were further investigated and supported by computational modeling. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0SDS of cas: 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.SDS of cas: 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Enhancement of atazanavir solubility using β-cyclodextrin based nanosponges was written by Venkatesh, D. N.. And the article was included in Special Publication – Royal Society of Chemistry in 2020.Product Details of 102-09-0 The following contents are mentioned in the article:

Cyclodextrins are capable in forming inclusion complexation with various mols. resulting in increased solubility of drugs. Recently nanosponges have gained considerable attention, owing to their biocompatibility, nanoporous in nature, capable of forming supra mol. inclusion complexes with both hydrophilic and lipophilic drugs. Nanosponges are nanostructured carriers prepared by reacting cyclodextrin with suitable cross linkers such as carbonyl diimidazole, hexamethylene and di-Ph carbonate. In the present study, Atazanavir (ATZ) was selected as it is BCS Il drug having low solubility (0.11 mg/I) with a log P value of 5.6.4. It is used in the treatment of Human Immunodeficiency Virus (HIV) infection with better potency, but low oral bioavailability. Atazanavir-β-cyclodextrin based nanosponges were prepared with varying concentration of 1,1 carbonyl diimidazole (CDI) as cross linker. The prepared nanosponges were characterized for FTIR spectroscopy study, SEM and in vitro dissolution study. A remarkable increase in the solubility and dissolution rate was observed However, in vivo studies are required to establish the potential effect of this formulation is necessary. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Product Details of 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Product Details of 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Design, Synthesis, and Biological Evaluation of 2-Formyl Tetrahydronaphthyridine Urea Derivatives as New Selective Covalently Reversible FGFR4 Inhibitors was written by Zhang, Zhen;Li, Jie;Chen, Hao;Huang, Jing;Song, Xiaojuan;Tu, Zheng-Chao;Zhang, Zhang;Peng, Lijie;Zhou, Yang;Ding, Ke. And the article was included in Journal of Medicinal Chemistry in 2022.HPLC of Formula: 102-09-0 The following contents are mentioned in the article:

Aberrant FGF19/FGFR4 signaling is an oncogenic driver force for the development of human hepatocellular carcinoma (HCC). A series of 2-formyl tetrahydronaphthyridine urea derivatives I (R = 2-phenylethynyl, 2-(pyridin-2-yl)ethynyl, 2-(3-methoxyphenyl)ethyl, etc.; R¹ = F, propan-2-yloxidanyl, cyclopentylaminyl, etc.) and II was designed and synthesized as new covalently reversible inhibitors of FGFR4. The representative compound II (R = 2-(pyridin-3-yl)ethynyl) (III) exhibited an IC₅₀ value of 5.4 nM against FGFR4 and demonstrated extraordinary kinome selectivity. Compound III also exhibited good oral pharmacokinetic properties with an AUC_(0-t) value of 38 950.06 h*ng/mL, a T_1/2 value of 3.06 h, and an oral bioavailability of 50.97%, at an oral dose of 25 mg/kg in Sprague-Dawley (SD) rats. Furthermore, compound III induced significant tumor regressions in a xenograft mouse model of Hep3B2.1-7 HCC cancer cells without an obvious sign of toxicity upon 30 mg/kg oral administration. Compound III may serve as a promising lead compound for further anticancer drug development. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0HPLC of Formula: 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ring opening copolymerization of e-caprolactone and diselenic macrolide carbonate for well-defined poly(ester-co-carbonate): kinetic evaluation and ROS/GSH responsiveness was written by Wang, Jiahao;Sun, Chuanhao;Hu, Jieni;Huang, Yanling;Lu, Yunxiang;Zhang, Yan. And the article was included in Polymer Chemistry in 2020.Application In Synthesis of Diphenyl carbonate The following contents are mentioned in the article:

A resurgence of interest has recently propelled poly(e-caprolactone) (PCL) back into the biomaterials arena. Herein, we reported a new poly(ester-co-carbonate) via the copolymerization of e-CL and a diselenic macrolide carbonate monomer (M_SeSe). The structure of the copolymer was confirmed by NMR, FTIR and GPC. The kinetic exptl. studies showed that the monomer reactivity ratios of e-CL (r₁) and M_SeSe (r₂) were different and the final sequence distribution of the copolymer was random, which agreed well with the theor. results based on d. functional theory (DFT) calculations The results of DSC and XRD consistently indicated that the copolymers were inclined to be amorphous with the increase in the M_SeSe fraction. UV, DLS and TEM techniques were employed to demonstrate the variation of transmittance, size and the morphol. of copolymer micelles subjected to the GSH and ROS environments, and the mechanism was clarified by FTIR and GPC, which demonstrated that the copolymers had rich environment responsiveness. Therefore, poly(ester-co-carbonate) with higher ROS and GSH sensitivity has great potential in the biomaterials field. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Application In Synthesis of Diphenyl carbonate).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of Diphenyl carbonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics