Author: Jessica.F

Safety of Ethyl tetradecanoateIn 2022, Zou, Yuke;Zhong, Yixin;Huang, Lihui;Xu, Wei;Wu, Yanping;Gao, Jia;Zhong, Kai;Gao, Hong published 《Effects of brown sugar addition and fermentation time on metabolites and microbial communities of Yibin Yacai》. 《LWT–Food Science and Technology》published the findings. The article contains the following contents:

Yibin Yacai is one of the most popular pickled vegetables in Sichuan made from special local stem mustard via spontaneous fermentation The final quality of the Yibin Yacai product depends on every manufacturing process that affects the microbial communities during fermentation In this study, the effects of brown sugar addition and fermentation time on physicochem. quality, flavor, and microbial communities of Yibin Yacai under five different fermentation conditions were investigated. The brown sugar addition can effectively increase the activities of microorganisms such as Lactobacillus and Debaryomyces, resulting in an increase in lactic acid content, sweet amino acids and umami amino acids. Furthermore, fermentation time plays a critical role in determining their physicochem. quality and flavor. The Yibin Yacai samples fermented for 5 years present the highest content of reducing sugar, amino acid nitrogen, esters, aldehydes, and olefins, while having the lowest salinity. These results indicate that the brown sugar addition and fermentation time could significantly influence the physicochem. and flavor qualities of the Yibin Yacai by tuning microbial communities during fermentation These findings reveal the importance of controlling manufacturing processes for traditionally fermented Yibin Yacai and provide a new perspective on the technol. innovation of fermented Yibin Yacai. And Ethyl tetradecanoate (cas: 124-06-1) was used in the research process.

Ethyl tetradecanoate(cas: 124-06-1) is a labeled component from essential oil of natural hawthorn perfume. Also frequently used in cosmetics, soaps, and flavorings.Safety of Ethyl tetradecanoateEthyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

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Stupak, Michal;Goodall, Ian;Tomaniova, Monika;Pulkrabova, Jana;Hajslova, Jana published 《A novel approach to assess the quality and authenticity of Scotch Whisky based on gas chromatography coupled to high resolution mass spectrometry》 in 2018. The article was appeared in 《Analytica Chimica Acta》. They have made some progress in their research.COA of Formula: C10H12O2 The article mentions the following:

Whisky is one of the most popular spirit drinks in the world. Unfortunately, this highly valued commodity is vulnerable to fraud. To detect fraudulent practices and document quality parameters, a number of laboratory tests based on various principles including chromatog. and spectroscopy have been developed. In most cases, the anal. methods are based on targeted screening strategies. Non-targeted screening (metabolomics fingerprinting) of (semi)volatile substances was used in our study. Following the pre-concentration of these compounds, either by solid phase microextraction (SPME) or by Et acetate extraction, gas chromatog. (GC) coupled to tandem mass spectrometry (Q-TOF mass analyzer) was employed. Unsupervised principal component anal. (PCA) and supervised partial least squares discriminant anal. (PLS-DA) were used for evaluation of data obtained by anal. of a unique set of 171 authentic whisky samples provided by the Scotch Whisky Research Institute. Very good separation of malt whiskies according to the type of cask in which they were matured (bourbon vs. bourbon and wine) was achieved, and significant ‘markers’ for bourbon and wine cask maturation, such as N-(3-methylbutyl) acetamide and 5-oxooxolane-2-carboxylic acid, were identified. Subsequently, the unique sample set was used to construct a statistical model for distinguishing malt and blended whiskies. In the final phase, 20 fake samples were analyzed and the data processed in the same way. Some differences could be observed in the (semi)volatile profiles of authentic and fake samples. Employing the statistical model developed by PLS-DA for this purpose, marker compounds that pos. distinguish fake samples were identified. To complete the study, the researchers used 1-Phenylethyl acetate (cas: 93-92-5) .

1-Phenylethyl acetate(cas:93-92-5) is a carboxylic ester. COA of Formula: C10H12O2 It may be prepared by acetylation of methyl phenyl carbinol; from 1-bromoethylbenzene and silver acetate in acetic acid; from benzaldehyde by reacting with magnesium methyl bromide and subsequent acetylation.

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HPLC of Formula: 106-02-5《Synthesis of 23-, 25-, 27-, and 29-Membered (Z)-Selective Unsaturated and Saturated Macrocyclic Lactones from 16- and 17-Membered Macrocyclic Lactones and Bromoalcohols by Wittig Reaction, Yamaguchi Macrolactonization, and Photoinduced Decarboxylative Radical Macrolactonization》 was published in 2019. The authors were Iwasaki, Tomoya;Tajimi, Yuka;Kameda, Kenta;Kingwell, Callum;Wcislo, William;Osaka, Kazuyuki;Yamawaki, Mugen;Morita, Toshio;Yoshimi, Yasuharu, and the article was included in《Journal of Organic Chemistry》. The author mentioned the following in the article:

A new strategy for the synthesis of 23-, 25-, 27-, and 29-membered (Z)-selective unsaturated and saturated macrocyclic lactones from com. available 16- and 17-membered macrocyclic lactones and bromoalcs. by Wittig reaction, Yamaguchi macrolactonization, and photoinduced decarboxylative radical macrolactonization is described. The position of the unsaturated part in the macrocyclic lactones can be controlled by changing the number of carbons in the starting materials. This protocol can provide facile access to the desired large-ring (Z)-selective unsaturated and saturated macrocyclic lactones from simple starting materials.Oxacyclohexadecan-2-one (cas: 106-02-5) were involved in the experimental procedure.

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.HPLC of Formula: 106-02-5 It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

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Yao, Di;Ma, Lixue;Wu, Mengna;Wang, Xiaoyu;Xu, Lei;Yu, Qiaoru;Wang, Changyuan published 《Effect of microbial communities on the quality characteristics of northeast soybean paste: Correlation between microorganisms and metabolites》 in 2022. The article was appeared in 《LWT–Food Science and Technology》. They have made some progress in their research.HPLC of Formula: 124-06-1 The article mentions the following:

To systematically explore the impact of microbial community composition on the quality characteristics of northeast soybean paste, the microbial community structure was determined by high-throughput sequencing technol. and the flavor substance, free amino acid (FAA) and biogenic amine (BA) contents were determined by HS-SPME-GC-MS and HPLC. Furthermore, the correlation between microorganisms and metabolites was investigated. The results indicated that the core bacteria mainly included Tetragenococcus, Bacillus and Lactobacillus; Candida_f__norank, Wickerhamomyces and Aspergillus were the dominant fungi. A total of 139 flavor compounds were detected in all samples, and decamethylcyclopentasiloxane, isoamyl phenylacetate and octamethylcyclotetrasiloxane accounted for the highest proportion. A total of 24 FAAs were detected in the soybean paste. Pantoea, Kroppenstedtia and Kocuria were significantly pos. correlated with most FAAs (p < 0.05). Addnl. 5 BAs were detected in the soybean paste, and the contents of BAs in Y4 were highest, which was affected by different microbes. This study provided relevant information for the microbial community composition and metabolites of northeast soybean paste, which was of great significance for understanding the characteristics and safety of soybean paste.Ethyl tetradecanoate (cas: 124-06-1) were involved in the experimental procedure.

Ethyl tetradecanoate(cas: 124-06-1) is a natural product found in Psidium guajava, Litchi chinensis, and other organisms.HPLC of Formula: 124-06-1Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

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Oettl, Sarah K.;Hubert, Jane;Nuzillard, Jean-Marc;Stuppner, Hermann;Renault, Jean-Hugues;Rollinger, Judith M. published 《Dereplication of depsides from the lichen Pseudevernia furfuracea by centrifugal partition chromatography combined to ¹³C nuclear magnetic resonance pattern recognition》 in 2014. The article was appeared in 《Analytica Chimica Acta》. They have made some progress in their research.Computed Properties of C10H12O4 The article mentions the following:

Lichens produce a diversity of secondary metabolites, among them depsides comprised of two or more hydroxybenzoic acid units linked by ester, ether, or C-C-bonds. During classic solid support-based purification processes, depsides are often hydrolyzed and in many cases time, consuming procedures result only in the isolation of decomposition products. In an attempt to avoid extensive purification steps while maintaining metabolite structure integrity, we propose an alternative method to identify the major depsides of a lichen crude extract (Pseudevernia furfuracea var. ceratea (Ach.) D.Hawksw., Parmeliaceae) directly within mixturesExploiting the acidic character of depsides and differences in polarity, the extract was fractionated by centrifugal partition chromatog. in the pH-zone refining mode resulting in twelve simplified mixtures of depsides. After ¹³C NMR anal. of the produced fractions, the major mol. structures were directly identified within the fraction series by using a recently developed pattern recognition method, which combines spectral data alignment and hierarchical clustering anal. The obtained clusters of ¹³C chem. shifts were assigned to their corresponding mol. structures with the help of an inhouse ¹³C NMR chem. shift database, resulting in six unambiguously identified compounds, namely Me β-orcinolcarboxylate (1), atranorin (2), 5-chloroatranorin (3), olivetol carboxylic acid (4), olivetoric acid (5), and olivetonide (6). And Methyl 2,4-dihydroxy-3,6-dimethylbenzoate (cas: 4707-47-5) was used in the research process.

Methyl 2,4-dihydroxy-3,6-dimethylbenzoate(4707-47-5) is used in biological study as role of androgens in inducing distinct response of epithelial-mesenchymal transition factors in human prostate cancer cells.Computed Properties of C10H12O4

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HPLC of Formula: 99-36-5《Cerium(III) triflate-catalyzed cycloaddition reaction in aqueous conditions to substituted naphthotriazolediones》 was published in 2022. The authors were Li, Ya-Syuan;Liang, Chien-Fu, and the article was included in《Journal of the Chinese Chemical Society (Weinheim, Germany)》. The author mentioned the following in the article:

In this study, the cerium(III) trifluoromethanesulfonate-catalyzed cycloaddition of 1,4-naphthoquinone with functionalized azides in aqueous solutions was used to synthesize naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives Moreover, this method boasts scalability and completes the synthesis of two key biol. compounds This method’s advantages are environmentally friendly reaction conditions, easy applicability in large-scale operations, broad structurally diverse products produced in high yields and the recyclability of catalysts. To complete the study, the researchers used Methyl 3-methylbenzoate (cas: 99-36-5) .

Methyl 3-methylbenzoate (cas: 99-36-5) is a common ester. Esters are widespread in nature and are widely used in industry. Several billion kilograms of polyesters are produced industrially annually, important products being polyethylene terephthalate, acrylate esters, and cellulose acetate.HPLC of Formula: 99-36-5

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Li, Chao;Liu, Xiuming;Qin, Yunhua;Wang, Jiajun;Zhang, Chengming;Li, Exian;Xu, Yong;Wu, Yiqin;Jiang, Ciqing published 《Quality trend analysis on cigarette cut filler based on characteristic volatile components in cut filler》. The research results were published in《Yancao Keji》 in 2017.Application of 93-92-5 The article conveys some information:

To investigate the variations in quality trend of cigarette cut fillers, HS-GC/MS was used to determine the contents of 50 volatile characteristic components in cut fillers of cigarettes of different batches and brands. By combining PCA-MD (Principal component anal.-Mahalanobis distance) statistical methods, the determined data were processed to analyze the variation trend of quality of cut filler. The results showed that the cut fillers of cigarettes of five batches of brand C could be classified into five groups. The contents of characteristic components differed greatly between the samples produced in 2015 and 2016. From July to Oct. in 2016, the contents of 50 volatile characteristic components in the cut fillers were basically consistent except that there was slight fluctuation in August, which could be attributed to the tobacco blend adjustment. For the samples produced in 2015, there were large differences in the contents of characteristic components in the cut fillers of brands C and D, indicating that PCA could be used to qual. describe the quality characteristics of the different brands. The MD of cut fillers differed greatly between brands C and D, and the MD of cut filler of brand D was 5 to 10 times as that of brand C, indicating that MD could be used to quant. characterize the quality variation of the cut filler. The research results can be applied to the quality consistency evaluation of the final cigarettes. And 1-Phenylethyl acetate (cas: 93-92-5) was used in the research process.

1-Phenylethyl acetate(cas:93-92-5) is a carboxylic ester. Application of 93-92-5 It may be prepared by acetylation of methyl phenyl carbinol; from 1-bromoethylbenzene and silver acetate in acetic acid; from benzaldehyde by reacting with magnesium methyl bromide and subsequent acetylation.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Reddy, R. Gajendra;Veeraval, Lenin;Maitra, Swati;Chollet-Krugler, Marylene;Tomasi, Sophie;Devehat, Francoise Lohezic-Le;Boustie, Joel;Chakravarty, Sumana published 《Lichen-derived compounds show potential for central nervous system therapeutics》 in 2016. The article was appeared in 《Phytomedicine》. They have made some progress in their research.Reference of Methyl 2,4-dihydroxy-3,6-dimethylbenzoate The article mentions the following:

Natural products from lichens are widely investigated for their biol. properties, yet their potential as central nervous system (CNS) therapeutic agents is less explored. The present study investigated the neuroactive properties of selected lichen compounds (atranorin, perlatolic acid, physodic acid and usnic acid), for their neurotrophic, neurogenic and acetylcholine esterase (AChE) activities. Neurotrophic activity (neurite outgrowth) was determined using murine neuroblastoma Neuro2A cells. A MTT assay was performed to assess the cytotoxicity of compounds at optimum neurotrophic activity. Neuro2A cells treated with neurotrophic lichen compounds were used for RT-PCR to evaluate the induction of genes that code for the neurotrophic markers BDNF and NGF. Immunoblotting was used to assess acetyl H3 and H4 levels, the epigenetic markers associated with neurotrophic and/or neurogenic activity. The neurogenic property of the compounds was determined using murine hippocampal primary cultures. AChE inhibition activity was performed using a modified Ellman’s esterase method. Lichen compounds atranorin, perlatolic acid, physodic acid and (+)-usnic acid showed neurotrophic activity in a preliminary cell-based screening based on Neuro2A neurite outgrowth. Except for usnic acid, no cytotoxic effects were observed for the two depsides (atranorin and perlatolic acid) and the alkyl depsidone (physodic acid). Perlatolic acid appears to be promising, as it also exhibited AChE inhibition activity and potent proneurogenic activity. The neurotrophic lichen compounds (atranorin, perlatolic acid, physodic acid) modulated the gene expression of BDNF and NGF. In addition, perlatolic acid showed increased protein levels of acetyl H3 and H4 in Neuro2A cells. These lichen depsides and depsidones showed neuroactive properties in vitro (Neuro2A cells) and ex vivo (primary neural stem or progenitor cells), suggesting their potential to treat CNS disorders. To complete the study, the researchers used Methyl 2,4-dihydroxy-3,6-dimethylbenzoate (cas: 4707-47-5) .

Methyl 2,4-dihydroxy-3,6-dimethylbenzoate(4707-47-5) is used in biological study as role of androgens in inducing distinct response of epithelial-mesenchymal transition factors in human prostate cancer cells.Reference of Methyl 2,4-dihydroxy-3,6-dimethylbenzoate

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