Cordoba, Ruben; Tormo, Nelida Salvador; Medarde, Antonio Fernandez; Plumet, Joaquin published the artcile< Antiangiogenic versus cytotoxic activity in analogues of aeroplysinin-1>, HPLC of Formula: 112-63-0, the main research area is angiogenesis inhibitor cytotoxic preparation aeroplysinin analog structure.
A series of analogs of the potentially angiogenic inhibitor aeroplysinin-1 1 were synthesized and their in vitro antiangiogenic and cytotoxic activities evaluated. In the case of epoxy ketone 6 and azlactone 36 the relationship sprouting inhibition assay/cytotoxicity in BAE cells was enhanced by one order and two orders of magnitude, resp., with respect to the reference These results imply more specific antiangiogenic properties for the synthesized derivatives
Bioorganic & Medicinal Chemistry published new progress about Antiangiogenic agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics