Bartels, Bjoern’s team published research in Bioorganic & Medicinal Chemistry in 2018-02-15 | 112-63-0

Bioorganic & Medicinal Chemistry published new progress about Alzheimer disease. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Bartels, Bjoern; Cueni, Philipp; Muri, Dieter; Koerner, Matthias published the artcile< Development of a safe and scalable route towards a tau PET tracer precursor>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is diazacarbazole scalable preparation tau PET tracer precursor; Buchwald-Hartwig amination; CH activation; Diazacarbazole; Direct arylation; PET tracer; Stille coupling; Suzuki-Miyaura cross-coupling; Tau.

A scalable 5-step synthesis of the diazacarbazole derivative I used as tau PET tracer precursor is reported. Key features of this synthesis include a Buchwald-Hartwig amination, a Pd catalyzed C-H activation and a Suzuki-Miyaura cross-coupling.

Bioorganic & Medicinal Chemistry published new progress about Alzheimer disease. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics