In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Axial-to-Central Chirality Transfer for Construction of Quaternary Stereocenters via Dearomatization of BINOLs, published in 2019-11-15, which mentions a compound: 415918-91-1, mainly applied to spiro benzochromene naphthalenone asym synthesis; binaphthol dearomatization axial chirality transfer propargyl carbonate enantioselective spirocyclization, Computed Properties of C36H30NO2P.
Herein, an axial-to-central chirality transfer strategy for the synthesis of chiral quaternary stereocenters via dearomatization of (S)-BINOLs is disclosed. The reaction of (S)-BINOL with a wide range of propargyl carbonates I (R = Me, cyclopropyl, Ph, 4-ClC6H4, 1-naphthyl, 2-benzothienyl, etc.) proceeded smoothly to afford chiral spiro compounds II in high yields with excellent enantioselectivities. In addition, the strategy was extended to kinetic resolution of rac-BINOLs albeit with moderate s value.
There is still a lot of research devoted to this compound(SMILES：C[C@@H](N(P1OC2=CC=C3C=CC=CC3=C2C4=C5C=CC=CC5=CC=C4O1)[C@@H](C6=CC=CC=C6)C)C7=CC=CC=C7)Computed Properties of C36H30NO2P, and with the development of science, more effects of this compound(415918-91-1) can be discovered.
Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics