Application of 6290-49-9, These common heterocyclic compound, 6290-49-9, name is Methyl 2-methoxyacetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A mixture of methyl methoxyacetate (52 g, 500 mmol), hydrazine hydrate (30 mL) washeated to reflux for 8 h. Excess hydrazine and water were removed under vacuum. The residuewas extracted with n-butanol, dried with NaaSC^. Excess w-butanol was removed to yield 45g ofhydrazide.
The synthetic route of 6290-49-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; AXYS PHARMACEUTICALS; WO2004/108661; (2004); A1;,
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