Novel complex N-heterocycles via intramolecular 1,5-electrocyclizations: octahydropyrido[4”,3”:2′,3′]cyclobuta[1′,2′:4,5]pyrrolo[2,3-b]pyridines was written by Walter, Harald;Sundermann, Carsten. And the article was included in Heterocycles in 1998.SDS of cas: 14667-47-1 This article mentions the following:
2-Amino-3-isoprenylpyridine (I) and 2-amino-5-chloro-3-isoprenylpyridine (II) are prepared The toluenesulfonic acid catalyzed reaction of I and II with 1-benzyl-, 1-benzoyl-, and 1-methylpiperidin-4-one lead to novel pyrrolo[2,3-b]pyridines (III; R1 = H, Cl; R2 = Me, benzyl, benzoyl) in good to excellent yields in diastereoisomerically pure form. An intramol. 1,5-electrocyclization of a dipolar reactive intermediate as a key step is proposed for the formation of III. In the experiment, the researchers used many compounds, for example, Methyl 2-aminonicotinate (cas: 14667-47-1SDS of cas: 14667-47-1).
Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.SDS of cas: 14667-47-1
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics