Syntheses and reactions of thiacyclanone-1,1-dioxides with diazoalkanes was written by Eistert, Bernd;Kueffner, Peter;Arackal, Thommen J.. And the article was included in Chemische Berichte in 1977.Category: esters-buliding-blocks This article mentions the following:
Thiacyclanone oxides I (m = 1, n = 1-5; m = n = 2, 3; m = 2, n = 3) reacted with RCH:N2 (R = H, Me) to give enol ethers II (R = H, Me, n = 1-5), epoxides III (R = H, Me, m = 1, n = 3; R = H: m = n = 2, 3; m = 2, n = 3), β-oxo sulfones IV (R = H, n = 3, 4; R = Me, n = 5) and ring-enlarged oxo sulfones V (R = Me: m = 1, n = 3, 4; m = n = 2; m = 2, n = 3; m = 3, n = 1, 2; R = H, m = n = 3), and VI, depending on the size of the ring and the positions of the CO and SO2 relative to each other. The enol ethers were easily hydrolyzed with mineral acids to form β-oxo sulfones I (m = 1, n = 1-5). In the presence of Lewis acids, N2:CHCO2Et gave II (R = CO2Et, n = 1, 2) and ring enlarged oxo esters V (R = CO2Et: m = 1, n = 1-5; m = 2, 3, n = 3; m = 3, 4, n = 1; m = 3, n =2). Only the γ-oxo sulfone I (m = n = 2) reacted with N2:CHCO2Et to give V (R = CO2Et, m = n = 2) as well as glycidic ester III (R = CO2Et, m = n = 2). The β-oxo esters were hydrolyzed and decarboxylated to give good yields of the oxo sulfones. In the ring expansion of oxo sulfones with RCH:N2 (R = Me, CO2Et), the diazo compound was preferably inserted between C-3 and C-4. In the experiment, the researchers used many compounds, for example, Methyl 2-(methylsulfonyl)acetate (cas: 62020-09-1Category: esters-buliding-blocks).
Methyl 2-(methylsulfonyl)acetate (cas: 62020-09-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics