Biocatalysed reduction of carboxylic acids to primary alcohols in aqueous medium: A novel synthetic capability of the zygomycete fungus Syncephalastrum racemosum was written by Brenna, Elisabetta;Cannavale, Flavia;Crotti, Michele;Parmeggiani, Fabio;Romagnolo, Alice;Spina, Federica;Varese, Giovanna Cristina. And the article was included in Journal of Molecular Catalysis B: Enzymatic in 2015.COA of Formula: C7H8O2S This article mentions the following:
The zygomycete fungus Syncephalastrum racemosum shows the remarkable capability of reducing carboxylic acids to primary alcs. in water medium, at ambient temperature and pressure. The reaction does not require mol. hydrogen, and in most cases affords quant. transformations. The results herein reported highlight the basic mol. scaffold that can be accepted by the fungus, the effects due to substituents, and also the possibility that carboxylic acids can be generated in the reaction medium by enzymic hydrolysis of the corresponding Me esters. This biocatalyzed reduction implements the scarcely supplied enzymic toolbox for the conversion of carboxylic groups into primary alcs., which can be exploited for the optimization of sustainable synthetic procedures. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9COA of Formula: C7H8O2S).
Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.COA of Formula: C7H8O2S
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics