The competitive rates of reaction of a series of substituted benzyl methyl ethers with N-bromosuccinimide was written by Lovins, R. E.;Andrews, L. J.;Keefer, R. M.. And the article was included in Journal of Organic Chemistry in 1965.Computed Properties of C10H12O3 This article mentions the following:
The relative rates of reaction of a series of nuclear-substituted benzyl methyl ethers (XC6H4CH2OCH3) with N-bromosuccinimide in carbon tetrachloride are not highly sensitive to the influence of ring substituents. The small variations in substituent effects observed for the reaction do not parallel those expected for a transition state involving development of negative charge on the benzylic carbon but rather favor a transition state involving positive polarization of the reaction center. On the basis of the substituent effects observed in the reaction of benzyl methyl ethers with N-bromosuccinimide and the results of a determination of the relative rates of reaction of p-nitro- and p-methoxyethylbenzene (XC6H4CH2CH3) and of p-methoxybenzyl cyanide (p-CH3OC6H4CH2CN) with N-bromosuccinimide, it has been concluded that the magnitude of the effect of a ring substituent X on the benzyl hydrogen abstraction process is controlled primarily by the ability of the group Y to contribute to the intrinsic stability of the radical (XC6H4CHY) being formed in the activation process. In the experiment, the researchers used many compounds, for example, Methyl 2-methoxy-4-methylbenzoate (cas: 81245-24-1Computed Properties of C10H12O3).
Methyl 2-methoxy-4-methylbenzoate (cas: 81245-24-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Computed Properties of C10H12O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics